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Volumn 3, Issue 3, 1997, Pages 341-345

Azodicarbonamide inhibits HIV-1 replication by targeting the nucleocapsid protein

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; AZOFORMAMIDE; NUCLEOCAPSID PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 16944362355     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0397-341     Document Type: Article
Times cited : (109)

References (20)
  • 1
    • 0019786215 scopus 로고
    • Primary structure of the low molecular weight nucleic acid-binding proteins of murine leukemia viruses
    • Henderson, L.E., Copeland,T.D., Sowder, R.C., Smythers, G.W. & Oroszlan, S. Primary structure of the low molecular weight nucleic acid-binding proteins of murine leukemia viruses. J. Biol. Chem. 256, 8400-8406 (1981).
    • (1981) J. Biol. Chem. , vol.256 , pp. 8400-8406
    • Henderson, L.E.1    Copeland, T.D.2    Sowder, R.C.3    Smythers, G.W.4    Oroszlan, S.5
  • 2
    • 0022695021 scopus 로고
    • Potential metal-binding domains in nucleic acid binding proteins
    • Berg, J.M. Potential metal-binding domains in nucleic acid binding proteins. Science 232, 485-487 (1986).
    • (1986) Science , vol.232 , pp. 485-487
    • Berg, J.M.1
  • 3
    • 0025142952 scopus 로고
    • The nucleocapsid protein isolated from HIV-1 particles binds zinc and forms retroviral-type zinc fingers
    • South, T.L. et al. The nucleocapsid protein isolated from HIV-1 particles binds zinc and forms retroviral-type zinc fingers. Biochem. 29, 7786-7789 (1990).
    • (1990) Biochem. , vol.29 , pp. 7786-7789
    • South, T.L.1
  • 5
    • 0027367521 scopus 로고
    • Trans-activation of the 5′ to 3′ viral DNA strand transfer by nucleocapsid protein during reverse transcription of HIV-1 RNA. C
    • Darlix, J.-L., Vincent, A., Gabus, C., De Rocquigny, H. & Roques, B. Trans-activation of the 5′ to 3′ viral DNA strand transfer by nucleocapsid protein during reverse transcription of HIV-1 RNA. C. R. Acad. Sci. III 316, 763-771 (1993).
    • (1993) R. Acad. Sci. III , vol.316 , pp. 763-771
    • Darlix, J.-L.1    Vincent, A.2    Gabus, C.3    De Rocquigny, H.4    Roques, B.5
  • 6
    • 0028113905 scopus 로고
    • Human immunodeficiency virus nucleocapsid protein accelerates strand transfer of the terminally redundant sequences involved in reverse transcription
    • You, J.C. & McHenery, C.S. Human immunodeficiency virus nucleocapsid protein accelerates strand transfer of the terminally redundant sequences involved in reverse transcription. J. Biol. Chem. 269, 31491-31495 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 31491-31495
    • You, J.C.1    McHenery, C.S.2
  • 7
    • 0025266663 scopus 로고
    • Mutations of RNA and protein sequences involved in human immunodeficiency virus type 1 packaging result in production of non infectious virus
    • Aldovini, A. & Young, R.A. Mutations of RNA and protein sequences involved in human immunodeficiency virus type 1 packaging result in production of non infectious virus. J. Virol. 64, 1920-1926 (1990).
    • (1990) J. Virol. , vol.64 , pp. 1920-1926
    • Aldovini, A.1    Young, R.A.2
  • 8
    • 0029986494 scopus 로고    scopus 로고
    • Genetic analysis of the zinc finger in the Moloney murine leukemia virus nucleocapsid domain: Replacement of zinc-coordinating residues with other zinc-coordinating residues yields noninfectious particles containing genomic RNA
    • Gorelick, R.J. et al. Genetic analysis of the zinc finger in the Moloney murine leukemia virus nucleocapsid domain: Replacement of zinc-coordinating residues with other zinc-coordinating residues yields noninfectious particles containing genomic RNA. J. Virol. 70, 2593-2597 (1996).
    • (1996) J. Virol. , vol.70 , pp. 2593-2597
    • Gorelick, R.J.1
  • 9
    • 0027523471 scopus 로고
    • Inhibition of HIV-1 infectivity by zinc-ejecting aromatic C-nitroso compounds
    • Rice, W.G. et al. Inhibition of HIV-1 infectivity by zinc-ejecting aromatic C-nitroso compounds. Nature 361, 473-475 (1993).
    • (1993) Nature , vol.361 , pp. 473-475
    • Rice, W.G.1
  • 10
    • 0027365825 scopus 로고
    • The site of action of 3-nitrosobenzamide on the infectivity process of human immunodeficiency virus in human lymphocytes
    • Rice, W.G. et al. The site of action of 3-nitrosobenzamide on the infectivity process of human immunodeficiency virus in human lymphocytes. Proc. Natl. Acad. Sci. USA 90, 9721-9724 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9721-9724
    • Rice, W.G.1
  • 11
    • 0028875771 scopus 로고
    • Inhibitors of HIV nucleocapsid protein zinc fingers as candidates for the treatment of AIDS
    • Rice, W.G. et al. Inhibitors of HIV nucleocapsid protein zinc fingers as candidates for the treatment of AIDS. Science 270, 1194-1197 (1995).
    • (1995) Science , vol.270 , pp. 1194-1197
    • Rice, W.G.1
  • 12
    • 0029954581 scopus 로고    scopus 로고
    • Virus-encoded zinc fingers as targets for antiviral chemotherapy
    • Rice, W.G. & Turpin, J.A. Virus-encoded zinc fingers as targets for antiviral chemotherapy. Reviews Med. Virol. 6, 187-199 (1996).
    • (1996) Reviews Med. Virol. , vol.6 , pp. 187-199
    • Rice, W.G.1    Turpin, J.A.2
  • 13
    • 0031050622 scopus 로고    scopus 로고
    • Inhibition of multiple phases of HIV-1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins
    • Rice, W.G. et al. Inhibition of multiple phases of HIV-1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins. Antimicrob. Agents.Chemother. 41, 419-426 (1997).
    • (1997) Antimicrob. Agents.Chemother. , vol.41 , pp. 419-426
    • Rice, W.G.1
  • 14
    • 9544252936 scopus 로고    scopus 로고
    • Evaluation of selected chemotypes in coupled cellular and molecular target-based screens identifies novel HIV-1 zinc finger inhibitors
    • Rice, W.G. et al. Evaluation of selected chemotypes in coupled cellular and molecular target-based screens identifies novel HIV-1 zinc finger inhibitors. J. Med. Chem. 39, 3606-3616 (1996).
    • (1996) J. Med. Chem. , vol.39 , pp. 3606-3616
    • Rice, W.G.1
  • 15
    • 0031024735 scopus 로고    scopus 로고
    • Reverse transcription of human immunodeficiency virus type 1 is blocked by retroviral zinc finger inhibitors
    • Turpin, J.A. et al. Reverse transcription of human immunodeficiency virus type 1 is blocked by retroviral zinc finger inhibitors. Antiviral. Chem. Chemother. 8, 60-69 (1997).
    • (1997) Antiviral. Chem. Chemother. , vol.8 , pp. 60-69
    • Turpin, J.A.1
  • 16
    • 0029791790 scopus 로고    scopus 로고
    • Inhibitors of HIV-1 zinc fingers prevent normal processing of Gag precursors and result in the release of noninfectious virus particles
    • Turpin, J.A. et al. Inhibitors of HIV-1 zinc fingers prevent normal processing of Gag precursors and result in the release of noninfectious virus particles. J. Virol. 70, 6180-6189 (1996).
    • (1996) J. Virol. , vol.70 , pp. 6180-6189
    • Turpin, J.A.1
  • 17
    • 0030010446 scopus 로고    scopus 로고
    • ADA, a potential anti-HIV drug
    • Vandevelde, M. et al. ADA, a potential anti-HIV drug. AIDS Res. Hum. Retro. 12, 567-568 (1996).
    • (1996) AIDS Res. Hum. Retro. , vol.12 , pp. 567-568
    • Vandevelde, M.1
  • 18
    • 0024543258 scopus 로고
    • 113Cd NMR studies of a 1:1 Cd adduct with an 18-residue zinc finger peptide from HIV-1 nucleic acid binding protein, p7
    • 113Cd NMR studies of a 1:1 Cd adduct with an 18-residue zinc finger peptide from HIV-1 nucleic acid binding protein, p7. J. Am. Chem. Soc. 111, 395-397 (1989).
    • (1989) J. Am. Chem. Soc. , vol.111 , pp. 395-397
    • South, T.L.1    Kim, B.2    Summers, M.F.3
  • 19
    • 0029798563 scopus 로고    scopus 로고
    • Docking enzyme-inhibitor complexes using a preference based free-energy surface
    • Wallqvist, A. & Covell, D.G. Docking enzyme-inhibitor complexes using a preference based free-energy surface. Proteins 25, 403-419 (1996).
    • (1996) Proteins , vol.25 , pp. 403-419
    • Wallqvist, A.1    Covell, D.G.2
  • 20
    • 0026034790 scopus 로고
    • Activities of human immunodeficiency virus (HIV) integration protein in vitro: Specific cleavage and integration of HIV DNA
    • Bushman, F.D. & Craigie, R. Activities of human immunodeficiency virus (HIV) integration protein in vitro: Specific cleavage and integration of HIV DNA. Proc. Natl. Acad. Sci. USA 88, 1339-1343 (1991).
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 1339-1343
    • Bushman, F.D.1    Craigie, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.