-
1
-
-
0033233243
-
2 homeostasis by hypoxia-inducible factor 1
-
2 homeostasis by hypoxia-inducible factor 1. Annu. Rev. Cell Dev. Biol. 15, 551-578 (1999).
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 551-578
-
-
Semenza, G.L.1
-
2
-
-
15444342958
-
2 homeostasis by hypoxia-inducible factor 1α
-
2 homeostasis by hypoxia-inducible factor 1α. Genes Dev. 12, 149-162 (1998).
-
(1998)
Genes Dev.
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
-
3
-
-
0034901463
-
Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology
-
Semenza, G.L. Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology. Trends Mol. Med. 7, 345-350 (2001).
-
(2001)
Trends Mol. Med.
, vol.7
, pp. 345-350
-
-
Semenza, G.L.1
-
4
-
-
0034529914
-
Suppression of tumor growth through disruption of hypoxia-inducible transcription
-
Kung, A.L., Wang, S., Kico, J.M., Kaelin, W.G. & Livingston, D.M. Suppression of tumor growth through disruption of hypoxia-inducible transcription. Nat. Med. 6, 1335-1340 (2000).
-
(2000)
Nat. Med.
, vol.6
, pp. 1335-1340
-
-
Kung, A.L.1
Wang, S.2
Kico, J.M.3
Kaelin, W.G.4
Livingston, D.M.5
-
6
-
-
0029753008
-
Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit
-
Huang, L.E., Arany, Z., Livingston, D.M. & Bunn, H.F. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit. J. Biol. Chem. 271, 32253-32259 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32253-32259
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
Bunn, H.F.4
-
7
-
-
0029944965
-
Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1
-
Jiang, B.H., Rue, E., Wang, G.L., Roe, R. & Semenza, G.L. Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1. J. Biol. Chem. 271, 17771-17778 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17771-17778
-
-
Jiang, B.H.1
Rue, E.2
Wang, G.L.3
Roe, R.4
Semenza, G.L.5
-
8
-
-
0037015019
-
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP
-
Semenza, G.L. Physiology meets biophysics: visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP. Proc. Natl. Acad. Sci. USA 99, 11570-11572 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 11570-11572
-
-
Semenza, G.L.1
-
9
-
-
0036469146
-
Transcription. Oxygen sensing gets a second wind
-
Bruick, R.K. & McKnight, S.L. Transcription. Oxygen sensing gets a second wind. Science 295, 807-808 (2002).
-
(2002)
Science
, vol.295
, pp. 807-808
-
-
Bruick, R.K.1
McKnight, S.L.2
-
10
-
-
0036469038
-
Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch
-
Lando, D., Peet, D.J., Whelan, D.A., Gorman, J.J. & Whitelaw, M.L. Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch. Science 295, 858-861 (2002).
-
(2002)
Science
, vol.295
, pp. 858-861
-
-
Lando, D.1
Peet, D.J.2
Whelan, D.A.3
Gorman, J.J.4
Whitelaw, M.L.5
-
11
-
-
0035887011
-
FIH-1: A novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
-
Mahon, P.C., Hirota, K. & Semenza, G.L. FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev. 15, 2675-2686 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 2675-2686
-
-
Mahon, P.C.1
Hirota, K.2
Semenza, G.L.3
-
12
-
-
0037097861
-
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
-
Lando, D. et al. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev. 16, 1466-1471 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 1466-1471
-
-
Lando, D.1
-
13
-
-
18544386401
-
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family
-
Hewitson, K.S. et al. Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family. J. Biol. Chem. 277, 26351-26355 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 26351-26355
-
-
Hewitson, K.S.1
-
14
-
-
0036846033
-
Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the β-carbon of asparagine-803
-
McNeill, L.A. et al. Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the β-carbon of asparagine-803. Biochem. J. 367, 571-575 (2002).
-
(2002)
Biochem. J.
, vol.367
, pp. 571-575
-
-
McNeill, L.A.1
-
15
-
-
0037117479
-
Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1α
-
Freedman, S.J. et al. Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1α. Proc. Natl. Acad. Sci. USA 99, 5367-5372 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5367-5372
-
-
Freedman, S.J.1
-
16
-
-
0037117486
-
Structural basis for Hif-1 α/CBP recognition in the cellular hypoxic response
-
Dames, S.A., Martinez-Yamout, M., De Guzman, R.N., Dyson, H.J. & Wright, P.E. Structural basis for Hif-1 α/CBP recognition in the cellular hypoxic response. Proc. Natl. Acad. Sci. USA 99, 5271-5276 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5271-5276
-
-
Dames, S.A.1
Martinez-Yamout, M.2
De Guzman, R.N.3
Dyson, H.J.4
Wright, P.E.5
-
17
-
-
85081424372
-
Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and VHL
-
Lee, C., Kim, S.J., Jeong, D.G., Lee, S.M. & Ryu, S.E. Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and VHL. J. Biol. Chem. (2002).
-
(2002)
J. Biol. Chem.
, vol.1
-
-
Lee, C.1
Kim, S.J.2
Jeong, D.G.3
Lee, S.M.4
Ryu, S.E.5
-
18
-
-
0037035851
-
Structure of an HIF-1α-pVHL complex: Hydroxyproline recognition in signaling
-
Min, J.H. et al. Structure of an HIF-1α-pVHL complex: hydroxyproline recognition in signaling. Science 296, 1886-1889 (2002).
-
(2002)
Science
, vol.296
, pp. 1886-1889
-
-
Min, J.H.1
-
19
-
-
18444368709
-
Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
-
Hon, W.C. et al. Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL. Nature 417, 975-978 (2002).
-
(2002)
Nature
, vol.417
, pp. 975-978
-
-
Hon, W.C.1
-
20
-
-
0037180452
-
Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway
-
Dann, C.E. 3rd, Bruick, R.K. & Deisenhofer, J. Structure of factor-inhibiting hypoxia-inducible factor 1: an asparaginyl hydroxylase involved in the hypoxic response pathway. Proc. Natl. Acad. Sci. USA 99, 15351-15356 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 15351-15356
-
-
Dann C.E. III1
Bruick, R.K.2
Deisenhofer, J.3
-
21
-
-
0037449811
-
Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1α
-
Elkins, J.M. et al. Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1α. J. Biol. Chem. 278, 1802-1806 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1802-1806
-
-
Elkins, J.M.1
-
22
-
-
0037040942
-
Human CREB-binding protein/p300-interacting transactivator with ED-rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2
-
Braganca, J. et al. Human CREB-binding protein/p300-interacting transactivator with ED-rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2. J. Biol. Chem. 277, 8559-8565 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8559-8565
-
-
Braganca, J.1
-
23
-
-
0032736054
-
Molecular cloning and chromosomal localization of the human CITED2 gene encoding p36srj/Mrg1
-
Leung, M.K., Jones, T., Michels, C.L., Livingston, D.M. & Bhattacharya, S. Molecular cloning and chromosomal localization of the human CITED2 gene encoding p36srj/Mrg1. Genomics 61, 307-313 (1999).
-
(1999)
Genomics
, vol.61
, pp. 307-313
-
-
Leung, M.K.1
Jones, T.2
Michels, C.L.3
Livingston, D.M.4
Bhattacharya, S.5
-
24
-
-
0029861328
-
msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation
-
Shioda, T., Fenner, M.H. & Isselbacher, K.J. msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation. Proc. Natl Acad. Sci. USA 93, 12298-12303 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 12298-12303
-
-
Shioda, T.1
Fenner, M.H.2
Isselbacher, K.J.3
-
25
-
-
0001190221
-
MRG1, the product of a melanocyte-specific gene-related gene, is a cytokine-inducible transcription factor with transformation activity
-
Sun, H.B., Zhu, Y.X., Yin, T., Sledge, G. & Yang, Y.C. MRG1, the product of a melanocyte-specific gene-related gene, is a cytokine-inducible transcription factor with transformation activity. Proc. Natl. Acad. Sci. USA 95, 13555-13560 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13555-13560
-
-
Sun, H.B.1
Zhu, Y.X.2
Yin, T.3
Sledge, G.4
Yang, Y.C.5
-
26
-
-
0034708737
-
The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors
-
Yahata, T. et al. The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors. J. Biol. Chem. 275, 8825-8834 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8825-8834
-
-
Yahata, T.1
-
27
-
-
0035477480
-
Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein
-
Yahata, T. et al. Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein. Genes Dev. 15, 2598-2612 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 2598-2612
-
-
Yahata, T.1
-
28
-
-
0032900610
-
Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1
-
Bhattacharya, S. et al. Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1. Genes. Dev. 13, 64-75 (1999).
-
(1999)
Genes. Dev.
, vol.13
, pp. 64-75
-
-
Bhattacharya, S.1
-
29
-
-
0036679122
-
The essential role of Cited2, a negative regulator for HIF-1α, in heart development and neurulation
-
Yin, Z. et al. The essential role of Cited2, a negative regulator for HIF-1α, in heart development and neurulation. Proc. Natl. Acad. Sci. USA 99, 10488-10493 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10488-10493
-
-
Yin, Z.1
-
30
-
-
18344389337
-
Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator
-
Bamforth, S.D. et al. Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. Nat. Genet. 29, 469-474 (2001).
-
(2001)
Nat. Genet.
, vol.29
, pp. 469-474
-
-
Bamforth, S.D.1
-
31
-
-
0035957953
-
CREB-binding protein and p300 in transcriptional regulation
-
Vo, N. & Goodman, R.H. CREB-binding protein and p300 in transcriptional regulation. J. Biol. Chem. 276, 13505-13508 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 13505-13508
-
-
Vo, N.1
Goodman, R.H.2
-
32
-
-
0003187567
-
The atomic structure of protein-protein recognition sites
-
Lo Conte, L., Chothia, C. & Janin, J. The atomic structure of protein-protein recognition sites. J. Mol. Biol. 285, 2177-2198 (1999).
-
(1999)
J. Mol. Biol.
, vol.285
, pp. 2177-2198
-
-
Lo Conte, L.1
Chothia, C.2
Janin, J.3
-
33
-
-
0034692876
-
Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP
-
De Guzman, R.N., Liu, H.Y., Martinez-Yamout, M., Dyson, H.J. & Wright, P.E. Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP. J. Mol. Biol. 303, 243-253 (2000).
-
(2000)
J. Mol. Biol.
, vol.303
, pp. 243-253
-
-
De Guzman, R.N.1
Liu, H.Y.2
Martinez-Yamout, M.3
Dyson, H.J.4
Wright, P.E.5
-
34
-
-
0035793584
-
Molecular mechanism of hypoxia-inducible factor 1α-p300 interaction. A leucine-rich interface regulated by a single cysteine
-
Gu, J., Milligan, J. & Huang, L.E. Molecular mechanism of hypoxia-inducible factor 1α-p300 interaction. A leucine-rich interface regulated by a single cysteine. J. Biol. Chem. 276, 3550-3554 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3550-3554
-
-
Gu, J.1
Milligan, J.2
Huang, L.E.3
-
35
-
-
0035499603
-
β-catenin: Molecular plasticity and drug design
-
Daniels, D.L., Eklof Spink, K. & Weis, W.I. β-catenin: molecular plasticity and drug design. Trends Biochem. Sci. 26, 672-678 (2001).
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 672-678
-
-
Daniels, D.L.1
Eklof Spink, K.2
Weis, W.I.3
-
36
-
-
0036468397
-
Coupling of folding and binding for unstructured proteins
-
Dyson, H.J. & Wright, P.E. Coupling of folding and binding for unstructured proteins. Curr. Opin. Struct. Biol. 12, 54-60 (2002).
-
(2002)
Curr. Opin. Struct. Biol.
, vol.12
, pp. 54-60
-
-
Dyson, H.J.1
Wright, P.E.2
-
38
-
-
0030826444
-
Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein
-
Matsuo, H. et al. Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein. Nat. Struct. Biol. 4, 717-724 (1997).
-
(1997)
Nat. Struct. Biol.
, vol.4
, pp. 717-724
-
-
Matsuo, H.1
-
39
-
-
0000088628
-
Processing of multi-dimensional NMR data with the new software PROSA
-
Guntert, P., Dotsch, V., Wider, G. & Wuthrich, K. Processing of multi-dimensional NMR data with the new software PROSA. J. Biomol. NMR 2, 619-629 (1992).
-
(1992)
J. Biomol. NMR
, vol.2
, pp. 619-629
-
-
Guntert, P.1
Dotsch, V.2
Wider, G.3
Wuthrich, K.4
-
40
-
-
0343459675
-
The program XEASY for computer-supported NMR spectral analysis of biological macromolecules
-
Bartels, C., Xia, T.-H., Billeter, M., Guntert, P. & Wuthrich, K. The program XEASY for computer-supported NMR spectral analysis of biological macromolecules. J. Biomol. NMR 5, 1-10 (1995).
-
(1995)
J. Biomol. NMR
, vol.5
, pp. 1-10
-
-
Bartels, C.1
Xia, T.-H.2
Billeter, M.3
Guntert, P.4
Wuthrich, K.5
-
41
-
-
0033003335
-
Protein backbone angle restraints from searching a database for chemical shift and sequence homology
-
Cornilescu, G., Delaglio, F. & Bax, A. Protein backbone angle restraints from searching a database for chemical shift and sequence homology. J. Biomol. NMR 13, 289-302 (1999).
-
(1999)
J. Biomol. NMR
, vol.13
, pp. 289-302
-
-
Cornilescu, G.1
Delaglio, F.2
Bax, A.3
-
42
-
-
0031576336
-
Torsion angle dynamics for NMR structure calculation with the new program DYANA
-
Guntert, P., Mumenthaler, C. & Wuthrich, K. Torsion angle dynamics for NMR structure calculation with the new program DYANA. J. Mol. Biol. 273, 283-298 (1997).
-
(1997)
J. Mol. Biol.
, vol.273
, pp. 283-298
-
-
Guntert, P.1
Mumenthaler, C.2
Wuthrich, K.3
-
43
-
-
0023732144
-
Determination of three-dimensional structures of proteins from interproton distance data by dynamical simulated annealing from a random array of atoms. Circumventing problems associated with folding
-
Nilges, M., Clore, G.M. & Gronenborn, A.M. Determination of three-dimensional structures of proteins from interproton distance data by dynamical simulated annealing from a random array of atoms. Circumventing problems associated with folding. FEBS Lett. 239, 129-136 (1988).
-
(1988)
FEBS Lett.
, vol.239
, pp. 129-136
-
-
Nilges, M.1
Clore, G.M.2
Gronenborn, A.M.3
-
45
-
-
0030339738
-
AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR
-
Laskowski, R.A., Rullmann, J.A., MacArthur, M.W., Kaptein, R. & Thornton, J.M. AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR. J. Biomol. NMR 8, 477-486 (1996).
-
(1996)
J. Biomol. NMR
, vol.8
, pp. 477-486
-
-
Laskowski, R.A.1
Rullmann, J.A.2
MacArthur, M.W.3
Kaptein, R.4
Thornton, J.M.5
-
46
-
-
0029881007
-
MolMol: A program for display and analysis of macromolecular structures
-
Koradi, R., Billeter, M. & Wuthrich, K. MolMol: a program for display and analysis of macromolecular structures. J. Mol. Graph. 14, 51-55, 29-32 (1996).
-
(1996)
J. Mol. Graph.
, vol.14
, pp. 51-55
-
-
Koradi, R.1
Billeter, M.2
Wuthrich, K.3
-
47
-
-
0027241860
-
Structures of DNA-binding mutant zinc finger domains: Implications for DNA binding
-
Hoffman, R.C., Horvath, S.J. & Klevit, R.E. Structures of DNA-binding mutant zinc finger domains: implications for DNA binding. Protein Sci. 2, 951-965 (1993).
-
(1993)
Protein Sci.
, vol.2
, pp. 951-965
-
-
Hoffman, R.C.1
Horvath, S.J.2
Klevit, R.E.3
|