-
2
-
-
0033051828
-
The von Hippel-Lindau tumour suppressor protein: New perspectives
-
Ohh M, Kaelin WG Jr. The von Hippel-Lindau tumour suppressor protein: new perspectives. Mol Med Today. 1999;5(6):257-263.
-
(1999)
Mol Med Today
, vol.5
, Issue.6
, pp. 257-263
-
-
Ohh, M.1
Kaelin Jr., W.G.2
-
3
-
-
0031862350
-
Molecular genetic analysis of von Hippel-Lindau disease
-
Richards FM, Webster AR, McMahon R, Woodward ER, Rose S, Maher ER. Molecular genetic analysis of von Hippel-Lindau disease. J Intern Med. 1998;243(6):527-533.
-
(1998)
J Intern Med
, vol.243
, Issue.6
, pp. 527-533
-
-
Richards, F.M.1
Webster, A.R.2
McMahon, R.3
Woodward, E.R.4
Rose, S.5
Maher, E.R.6
-
4
-
-
0011153988
-
Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma
-
Kovacs G, Erlandsson R, Boldog F, et al. Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma. Proc Natl Acad Sci USA. 1988;85(5):1571-1575.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, Issue.5
, pp. 1571-1575
-
-
Kovacs, G.1
Erlandsson, R.2
Boldog, F.3
-
5
-
-
0023181644
-
Loss of alleles of loci on the short arm of chromosome 3 in renal cell carcinoma
-
Zbar B, Brauch H, Talmadge C, Linehan M. Loss of alleles of loci on the short arm of chromosome 3 in renal cell carcinoma. Nature. 1987;327(6124):721- 724.
-
(1987)
Nature
, vol.327
, Issue.6124
, pp. 721-724
-
-
Zbar, B.1
Brauch, H.2
Talmadge, C.3
Linehan, M.4
-
6
-
-
0018736628
-
Hereditary renal-cell carcinoma associated with a chromosomal translocation
-
Cohen AJ, Li FP, Berg S, et al. Hereditary renal-cell carcinoma associated with a chromosomal translocation. N Engl J Med. 1979;301(11):592-595.
-
(1979)
N Engl J Med
, vol.301
, Issue.11
, pp. 592-595
-
-
Cohen, A.J.1
Li, F.P.2
Berg, S.3
-
7
-
-
0024517466
-
Tissue-specific expression of a constitutional 3;6 translocation: Development of multiple bilateral renal-cell carcinomas
-
Kovacs G, Brusa P, De Riese W. Tissue-specific expression of a constitutional 3;6 translocation: development of multiple bilateral renal-cell carcinomas. Int J Cancer. 1989;43(3):422-127.
-
(1989)
Int J Cancer
, vol.43
, Issue.3
, pp. 422-1127
-
-
Kovacs, G.1
Brusa, P.2
De Riese, W.3
-
8
-
-
0019998262
-
Familial renal cell carcinoma with a 3;11 chromosome translocation limited to tumor cells
-
Pathak S, Strong LC, Ferrell RE, Trindade A. Familial renal cell carcinoma with a 3;11 chromosome translocation limited to tumor cells. Science. 1982;217(4563):939-941.
-
(1982)
Science
, vol.217
, Issue.4563
, pp. 939-941
-
-
Pathak, S.1
Strong, L.C.2
Ferrell, R.E.3
Trindade, A.4
-
9
-
-
0023865666
-
Von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma
-
Seizinger BR, Rouleau GA, Ozelius LJ, et al. von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma. Nature. 1988;332(6161):268-269.
-
(1988)
Nature
, vol.332
, Issue.6161
, pp. 268-269
-
-
Seizinger, B.R.1
Rouleau, G.A.2
Ozelius, L.J.3
-
10
-
-
0027457130
-
Detailed genetic mapping of the von Hippel-Lindau disease tumour suppressor gene
-
Richards FM, Maher ER, Latif F, et al. Detailed genetic mapping of the von Hippel-Lindau disease tumour suppressor gene. J Med Genet. 1993;30(2):104-107.
-
(1993)
J Med Genet
, vol.30
, Issue.2
, pp. 104-107
-
-
Richards, F.M.1
Maher, E.R.2
Latif, F.3
-
11
-
-
0027371521
-
Von Hippel-Lindau disease: Identification of deletion mutations by pulsed-field gel electrophoresis
-
Yao M, Latif F, Orcutt ML, et al. von Hippel-Lindau disease: identification of deletion mutations by pulsed-field gel electrophoresis. Hum Genet. 1993;92(6):605-614.
-
(1993)
Hum Genet
, vol.92
, Issue.6
, pp. 605-614
-
-
Yao, M.1
Latif, F.2
Orcutt, M.L.3
-
12
-
-
0027240519
-
Identification of the von Hippel-Lindau disease tumor suppressor gene
-
Latif F, Tory K, Gnarra J, et al. Identification of the von Hippel-Lindau disease tumor suppressor gene. Science. 1993;260(5112):1317-1320.
-
(1993)
Science
, vol.260
, Issue.5112
, pp. 1317-1320
-
-
Latif, F.1
Tory, K.2
Gnarra, J.3
-
13
-
-
0028981766
-
Germline mutations in the von Hippel-Lindau disease tumor suppressor gene: Correlations with phenotype
-
Chen F, Kishida T, Yao M, et al. Germline mutations in the von Hippel-Lindau disease tumor suppressor gene: correlations with phenotype. Hum Mutat. 1995;5(1):66-75.
-
(1995)
Hum Mutat
, vol.5
, Issue.1
, pp. 66-75
-
-
Chen, F.1
Kishida, T.2
Yao, M.3
-
14
-
-
0035253381
-
The von Hippel-Lindau tumor suppressor protein
-
Ivan M, Kaelin WG Jr. The von Hippel-Lindau tumor suppressor protein. Curr Opin Genet Dev. 2001;11(1):27-34.
-
(2001)
Curr Opin Genet Dev
, vol.11
, Issue.1
, pp. 27-34
-
-
Ivan, M.1
Kaelin Jr., W.G.2
-
15
-
-
0033574737
-
Structure of the VHL-ElonginC-ElonginB complex: Implications for VHL tumor suppressor function
-
Stebbins CE, Kaelin WG Jr, Pavletich NP. Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function. Science. 1999;284(5413):455-461.
-
(1999)
Science
, vol.284
, Issue.5413
, pp. 455-461
-
-
Stebbins, C.E.1
Kaelin Jr., W.G.2
Pavletich, N.P.3
-
16
-
-
0035852668
-
Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor
-
Haase VH, Glickman JN, Socolovsky M, Jaenisch R. Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor. Proc Natl Acad Sci USA. 2001;98(4):1583-1588.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.4
, pp. 1583-1588
-
-
Haase, V.H.1
Glickman, J.N.2
Socolovsky, M.3
Jaenisch, R.4
-
17
-
-
0030847165
-
Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice
-
Gnarra JR, Ward JM, Porter FD, et al. Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice. Proc Natl Acad Sci USA. 1997;94(17):9102-9107.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.17
, pp. 9102-9107
-
-
Gnarra, J.R.1
Ward, J.M.2
Porter, F.D.3
-
18
-
-
0033529656
-
Perspectives on oxygen sensing
-
Semenza GL. Perspectives on oxygen sensing. Cell 1999;98(3):281-284.
-
(1999)
Cell
, vol.98
, Issue.3
, pp. 281-284
-
-
Semenza, G.L.1
-
19
-
-
0035812772
-
HIF-1, O(2), and the 3 PHDs: How animal cells signal hypoxia to the nucleus
-
Semenza GL. HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus. Cell. 2001;107(1):1-3.
-
(2001)
Cell
, vol.107
, Issue.1
, pp. 1-3
-
-
Semenza, G.L.1
-
20
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell PH, Wiesener MS, Chang GW, et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature. 1999;399(6733):271-275.
-
(1999)
Nature
, vol.399
, Issue.6733
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
-
21
-
-
0034682783
-
Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
-
Cockman ME, Masson N, Mole DR, et al. Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein. J Biol Chem. 2000;275(33):25733-25741.
-
(2000)
J Biol Chem
, vol.275
, Issue.33
, pp. 25733-25741
-
-
Cockman, M.E.1
Masson, N.2
Mole, D.R.3
-
22
-
-
0033776536
-
Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein
-
Ohh M, Park CW, Ivan M, et al. Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. Nat Cell Biol. 2000;2(7):423-427.
-
(2000)
Nat Cell Biol
, vol.2
, Issue.7
, pp. 423-427
-
-
Ohh, M.1
Park, C.W.2
Ivan, M.3
-
23
-
-
0034663894
-
Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein
-
Tanimoto K, Makino Y, Pereira T, Poellinger L. Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein. EMBO J. 2000;19(16):4298-4309.
-
(2000)
EMBO J
, vol.19
, Issue.16
, pp. 4298-4309
-
-
Tanimoto, K.1
Makino, Y.2
Pereira, T.3
Poellinger, L.4
-
24
-
-
0035917313
-
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: Implications for O2 sensing
-
Ivan M, Kondo K, Yang H, et al. HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science. 2001;292(5516):464-468.
-
(2001)
Science
, vol.292
, Issue.5516
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
-
25
-
-
0035917808
-
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
-
Jaakkola P, Mole DR, Tian YM, et al. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science. 2001;292(5516):468-472.
-
(2001)
Science
, vol.292
, Issue.5516
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
-
26
-
-
0035903468
-
Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
-
Masson N, Willam C, Maxwell PH, Pugh CW, Ratcliffe PJ. Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation. EMBO J. 2001;20(18):5197-5206.
-
(2001)
EMBO J
, vol.20
, Issue.18
, pp. 5197-5206
-
-
Masson, N.1
Willam, C.2
Maxwell, P.H.3
Pugh, C.W.4
Ratcliffe, P.J.5
-
27
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
Epstein AC, Gleadle JM, McNeill LA, et al. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell. 2001;107(1):43-54.
-
(2001)
Cell
, vol.107
, Issue.1
, pp. 43-54
-
-
Epstein, A.C.1
Gleadle, J.M.2
McNeill, L.A.3
-
28
-
-
0035834409
-
A conserved family of prolyl-4-hydroxylases that modify HIF
-
Bruick RK, McKnight SL. A conserved family of prolyl-4-hydroxylases that modify HIF. Science. 2001;294(5545):1337-1340.
-
(2001)
Science
, vol.294
, Issue.5545
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
29
-
-
0034253588
-
Evolution and function of ubiquitin-like protein-conjugation systems
-
Hochstrasser M. Evolution and function of ubiquitin-like protein-conjugation systems. Nat Cell Biol. 2000;2(8):E153-E157.
-
(2000)
Nat Cell Biol
, vol.2
, Issue.8
-
-
Hochstrasser, M.1
-
30
-
-
0034065822
-
Ubiquitin-mediated proteolysis: Biological regulation via destruction
-
Ciechanover A, Orian A, Schwartz AL. Ubiquitin-mediated proteolysis: biological regulation via destruction. Bioessays. 2000;22(5):442-451.
-
(2000)
Bioessays
, vol.22
, Issue.5
, pp. 442-451
-
-
Ciechanover, A.1
Orian, A.2
Schwartz, A.L.3
-
31
-
-
0033279836
-
SCF and Cullin/Ring H2-based ubiquitin ligases
-
Deshaies RJ. SCF and Cullin/Ring H2-based ubiquitin ligases. Annu Rev Cell Dev Biol. 1999;15:435-467.
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 435-467
-
-
Deshaies, R.J.1
-
32
-
-
0033597126
-
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
-
Gong L, Yeh ET. Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway. J Biol Chem. 1999;274(17):12036-12042.
-
(1999)
J Biol Chem
, vol.274
, Issue.17
, pp. 12036-12042
-
-
Gong, L.1
Yeh, E.T.2
-
33
-
-
0032522382
-
A novel protein modification pathway related to the ubiquitin system
-
Liakopoulos D, Doenges G, Matuschewski K, Jentsch S. A novel protein modification pathway related to the ubiquitin system. EMBO J. 1998;17(8):2208-2214.
-
(1998)
EMBO J
, vol.17
, Issue.8
, pp. 2208-2214
-
-
Liakopoulos, D.1
Doenges, G.2
Matuschewski, K.3
Jentsch, S.4
-
34
-
-
0036195134
-
An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells
-
Ohh M, Kim WY, Moslehi JJ, et al. An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells. EMBO Rep. 2002;3(2):177-182.
-
(2002)
EMBO Rep
, vol.3
, Issue.2
, pp. 177-182
-
-
Ohh, M.1
Kim, W.Y.2
Moslehi, J.J.3
-
35
-
-
0034712842
-
A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination
-
Podust VN, Brownell JE, Gladysheva TB, et al. A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination. Proc Natl Acad Sci USA. 2000;97(9):4579-4584.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.9
, pp. 4579-4584
-
-
Podust, V.N.1
Brownell, J.E.2
Gladysheva, T.B.3
-
37
-
-
17844411190
-
NEDD8 recruits E2-ubiquitin to SCF E3 ligase
-
Kawakami T, Chiba T, Suzuki T, et al. NEDD8 recruits E2-ubiquitin to SCF E3 ligase. EMBO J. 2001;20(15):4003-4012.
-
(2001)
EMBO J
, vol.20
, Issue.15
, pp. 4003-4012
-
-
Kawakami, T.1
Chiba, T.2
Suzuki, T.3
-
38
-
-
0034663989
-
HIF-I and human disease: One highly involved factor
-
Semenza GL. HIF-I and human disease: one highly involved factor. Genes Dev. 2000;14(16):1983-1991.
-
(2000)
Genes Dev
, vol.14
, Issue.16
, pp. 1983-1991
-
-
Semenza, G.L.1
|