The healing rabbit medial collateral ligament of the knee responds to systemically administered glucocorticoids differently than the uninjured tissues of the same joint or the uninjured MCL: A paradoxical shift in impact on specific mRNA levels and MMP-13 protein expression in injured tissues

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1741, Issue 3, 2005, Pages 289-299

  Kydd, Alison S ^a   Achari, Yamini ^a   Lu, Ting ^a   Sciore, Paul ^a   Rattner, J B ^a   Hart, David A ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Glucocorticoid; Injury; Medial collateral ligament; MMP 13; Rabbit; Scar

Indexed keywords

BIGLYCAN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGENASE 3; CYCLOOXYGENASE 2 INHIBITOR; DECORIN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; LUCIFERASE; MESSENGER RNA; METHYLPREDNISOLONE ACETATE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; EXPERIMENTAL MODEL; FEMALE; GENE CONSTRUCT; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GRANULATION TISSUE; HORMONE RESPONSE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KNEE LIGAMENT INJURY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RABBIT; SCAR; SYNOVIOCYTE; TRANSCRIPTION REGULATION; WOUND HEALING;

ANALYSIS OF VARIANCE; ANIMALS; CELL LINE; CICATRIX; COLLAGEN; COLLAGENASES; CYCLOOXYGENASE 2; DNA PRIMERS; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; IMMUNOHISTOCHEMISTRY; LUCIFERASES; MATRIX METALLOPROTEINASE 13; MEDIAL COLLATERAL LIGAMENT, KNEE; MEMBRANE PROTEINS; PROMOTER REGIONS (GENETICS); PROTEOGLYCANS; RABBITS; RECEPTORS, GLUCOCORTICOID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

ORYCTOLAGUS CUNICULUS;

EID: 25144506138     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2005.05.001     Document Type: Article

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