Expression of heat shock protein 47(Hsp47) mRNA levels in rabbit connective tissues during the response to injury and in pregnancy

Biochemistry and Cell Biology

Volumn 78, Issue 4, 2000, Pages 511-518

  Hart, D A ^a   Reno, C ^a   Le Graverand, M P H ^a   Hoffman, L ^a   Kulyk, W ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Hsp47 and ligament injury; Hsp47 and meniscal injury; Hsp47 and mRNA levels; Hsp47 expression and pregnancy

Indexed keywords

COLLAGEN; HEAT SHOCK PROTEIN 47; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; CELL DAMAGE; CONNECTIVE TISSUE; CONTROLLED STUDY; FEMALE; KNEE LIGAMENT; MALE; NONHUMAN; PREGNANCY; PROTEIN EXPRESSION; RABBIT; SURGICAL STRESS;

EID: 0033830826     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o00-064     Document Type: Article

References (36)

1. Altered levels of extracellular matrix molecule mRNA in healing rabbit ligaments
2. Induction of heat shock protein protects mesangial cells against oxidative injury
3. Intracellular interaction of Hsp47 and type I collagen in corneal endothelial cells
4. Complex alterations in gene expression in knee ligaments of the skeletally mature multiparous rabbit during pregnancy
5. Pregnancy induces complex changes in the pattern of gene expression in knee ligaments of the adolescent rabbit
6. Molecular chaperones in cellular protein folding
7. Alterations in mRNA levels in articular cartilage during pregnancy in the rabbit
8. Molecular, matrix and cellular alterations in lapine menisci during the early stages of osteoarthritis development
9. Increased expression of heat-shock protein 47 is associated with overproduction of type I procollagen in systemic sclerosis skin fibroblasts
10. Hsp47 and Hsp70 gene expression is differentially regulated in a stress- and tissue-specific manner in zebrafish embryos
11. Hsp and chaperone distribution during endochondral bone development in mouse embryo
12. Coexpression of the collagen-binding stress protein Hsp47 gene and the alpha 1(I) and alpha 1(III) collagen genes in carbon tetrachloride-induced rat liver fibrosis
13. Expression and localization of collagen-binding stress protein Hsp47 in mouse embryo development: Comparison with types I and II collagen
14. Expression of Hsp70 in healing wounds of diabetic and nondibetic mice
15. Distribution of the collagen binding heat-shock protein in chicken tissues
16. The heat-shock response: Regulation and function of heat-shock proteins and molecular chaperones
17. Plasminogen activators and plasminogen activator inhibitors in connective tissues and connective tissue cells: Influence of the neuropeptide substance P on expression
18. Influence of exogenous growth factors on the synthesis and secretion of collagen types I and III by explants of normal and healing rabbit ligaments
19. Hsp47: A collagen-specific molecular chaperone
20. Regulation and function of collagen-specific molecular chaperone, Hsp47
21. Involvement of the stress protein Hsp47 in procollagen processing in the endoplasmic reticulum
22. Interactions between collagen-binding stress protein Hsp47 and collagen. Analysis of kinetic parameters by surface plasmon resonance biosensor
23. Cloning and characterization of a cDNA encoding the collagen-binding stress protein Hsp47 in zebrafish
24. Coexpression of collagens and collagen-binding heat shock protein 47 in human diabetic nephropathy and IgA nephropathy
25. Immunolocalization of collagen and collagen-binding heat shock protein 47 in fibrotic lung diseases
26. Rapid isolation of total RNA from small samples of hypocellular, dense connective tissues
27. Intracellular interaction of collagen-specific stress protein Hsp47 with newly synthesized procollagen
28. Semiquantitative reverse transcription-polymerase chain reaction analysis of mRNA for growth factors and growth factor receptors from normal and healing rabbit medial collateral ligament tissue
29. Hsp47 is localized to regions of type I collagen production in developing murine femurs and molars
30. Antisense oligonucleotides against collagen-binding stress protein Hsp47 suppress collagen accumulation in experimental glomerulonephritis
31. Alternative 5' splice site selection induced by heat shock
32. Histologic cartilage changes in a rabbit model of osteoarthritis
33. Molecular and cell biology of skin wound healing in a pig model
34. Transcriptional activation of the mouse Hsp47 gene in mouse osteoblast MC3T3-E1 cells by TGF-β1
35. Characterization of a model of osteoarthritis in the rabbit knee