Denervation impairs healing of the rabbit medial collateral ligament

Journal of Orthopaedic Research

Volumn 20, Issue 5, 2002, Pages 990-995

  Ivie, T J ^a   Bray, R C ^a   Salo, P T ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Biomechanics; Joint innervation; Laser Doppler perfusion imaging; Ligament injury; Neurogenic inflammation

Indexed keywords

BLOOD VESSELS; BONE; LIGAMENTS; NEUROLOGY; SKIN;

LIGAMENT HEALING;

FRACTURE FIXATION;

CARMINIC ACID; GELATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTONOMIC INNERVATION; BIOMECHANICS; BLOOD VOLUME; BONE BLOOD FLOW; CONTROLLED STUDY; DENERVATION; DENSITY; FEMALE; FEMORAL NERVE; HEALING; HYPOTHESIS; IN VIVO STUDY; INFUSION; KNEE LIGAMENT INJURY; LASER DOPPLER FLOWMETRY; NERVE TRANSECTION; NEUROGENIC INFLAMMATION; NONHUMAN; OUTCOMES RESEARCH; PRIORITY JOURNAL; RABBIT; REST; SAPHENOUS NERVE; SENSORY NERVE; STRESS STRAIN RELATIONSHIP; TISSUE REPAIR; VASCULARIZATION; WOUND HEALING IMPAIRMENT;

ANIMALS; BIOMECHANICS; DENERVATION; FEMALE; FEMORAL NERVE; MEDIAL COLLATERAL LIGAMENT, KNEE; MICROCIRCULATION; RABBITS; REGIONAL BLOOD FLOW; WOUND HEALING;

EID: 0036375284     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0736-0266(02)00026-8     Document Type: Article

References (43)

1. Effect of nerve injury on fracture healing
2. Healing of experimental fractures in the denervated limb of the rat
3. Development of nonunions in the rat fibula after removal of periosteal neural mechanoreceptors
4. Enhanced tendon healing with GDF 5 and 6
5. Bone morphogenetic proteins and tendon repair
6. Effects of neuropeptides on growth of cultivated rat molar pulp fibroblasts
7. Immobilization increases the vulnerability of rabbit medial collateral ligament autografts to creep
8. Sensory neuropeptides: Their role in inflammation and wound healing
9. Evaluation of laser Doppler imaging to measure blood flow in knee ligaments of adult rabbits
10. Coloured inicrosphere assessment of blood flow to knee ligaments in adult rabbits: Effects of injury
11. The early effects of joint immobilization on medial collateral ligament healing in an ACL-deficient knee: A gross anatomic and biomechanical investigation in the adult rabbit model
12. Calcitonin gene-related peptide promotes Schwann cell proliferation
13. Water content alters viscoelastic behaviour of the normal adolescent rabbit medial collateral ligament
14. Tachykinin regulation of basal synovial blood flow
15. Spatial heterogeneity of the effects of calcitonin gene-related peptide (CGRP) on the microvasculature of ligaments in the rabbit knee joint
16. Changes in synovial PO2 and blood flow in the rabbit knee joint due to stimulating the posterior articular nerve
17. OP-1 has more effect than mechanical signals in the control of tissue differentiation in healing rat tendons
18. Abnormality of the contralateral ligament after injuries of the medial collateral ligament. An experimental study in the rabbit
19. Injury location affects ligament healing. A morphologic and mechanical study of the healing rabbit medial collateral ligament
20. Topical application of nerve growth factor improves fracture healing in rats
21. Calcitonin gene-related peptide stimulates proliferation of human endothelial cells
22. Effects of neuropeptides on human lung fibroblast proliferation and chemotaxis
23. Local effector functions of capsaicin-sensitive sensory nerve endings: Involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides
24. Calcitonin gene-related peptide acts as a mitogen for human Gin-1 gingival fibroblasts by activating the MAP kinase signalling pathway
25. Sensory peptides as neuromodulators of wound heating in aged rats
26. The sympathomimetic agent, 6-hydroxydopamine, accelerates cutaneous wound healing
27. Original articles: Sympathetic denervation impairs epidermal healing in cutaneous wounds
28. The effects of temperature on the viscoelastic properties of the rabbit medial collateral ligament
29. Compressive compared with tensile loading of medial collateral ligament scar in vitro uniquely influences mRNA levels for aggrecan, collagen type II, and collagenase
30. Vascular volume determination of articular tissues in normal and anterior cruciate ligament-deficient rabbit knees
31. Morphological and immunohistochemical examination of nerves in normal and injured collateral ligaments of rat, rabbit, and human knee joints
32. Spatial variation in sympathetic influences on the vasculature of the synovium and medial collateral ligament of the rabbit knee joint
33. Neurogenic origin of articular hyperemia in early degenerative joint disease
34. Modulation of synovial blood flow by the calcitonin gene-related peptide (CGRP) receptor antagonist. CGRP(8-37)
35. Calcitonin gene related peptide enhances bone colony development in vitro
36. Neurogenic substance P stimulates osteogenesis in vitro
37. A new method of measuring the cross-sectional area of connective tissue structures
38. Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism
39. Nerve dependency in scarless fetal wound healing
40. Early medial collateral ligament scars have inferior creep behaviour
41. Knee immobilization inhibits biomechanical maturation of the rabbit medial collateral ligament
42. The effects of nerve injury on ligament healing in a rat model
43. Neuropeptide Y: A novel angiogenic factor from the sympathetic nerves and endothelium