Glucocorticoid signalling - Multiple variations of a common theme

Molecular and Cellular Endocrinology

Volumn 146, Issue 1-2, 1998, Pages 1-6

  Reichardt, Holger M ^a   Schütz, Günther ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

DNA binding; Glucocorticoid receptor; HPA axis; Transcription

Indexed keywords

CELL DNA; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; TRANSCRIPTION FACTOR;

ENHANCER REGION; FEEDBACK SYSTEM; HORMONAL REGULATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; STEROID METABOLISM; TRANSCRIPTION REGULATION;

EID: 0032567143     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(98)00208-1     Document Type: Article

References (38)

1. Arriza J.L., Weinberger C., Cerelli G., Glaser T.M., Handelin B.L., Housman D.E., Evans R.M. Cloning of human mineralocorticoid receptor complementary DNA: structural and functional relationship with the glucocorticoid receptor. Science. 237:1987;268-275.
2. Auphan N., DiDonato J.A., Rosette C., Helmberg A., Karin M. Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science. 270:1995;286-290.
3. Beato M., Chalepakis G., Schauer M., Slater E.P. DNA regulatory elements for steroid hormones. J. Steroid Biochem. 32:1989;737-747.
4. Beato M., Herrlich P., Schütz G. Steroid hormone receptors: many actors in search of a plot. Cell. 83:1995;851-857.
5. Caelles C., Gonzalez Sancho J.M., Munoz A. Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway. Genes Dev. 11:1997;3351-3364.
6. Caldenhoven E., Liden J., Wissink S., Van de Stolpe A., Raaijmakers J., Koenderman L., Okret S., Gustafsson J.A., Van der Saag P.T. Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids. Mol. Endocrinol. 9:1995;401-412.
7. Chang T.J., Scher B.M., Waxman S., Scher W. Inhibition of mouse GATA-1 function by the glucocorticoid receptor: possible mechanism of steroid inhibition of erythroleukemia cell differentiation. Mol. Endocrinol. 7:1993;528-542.
8. Chapman M.S., Askew D.J., Kuscuoglu U., Miesfeld R.L. Transcriptional control of steroid-regulated apoptosis in murine thymoma cells. Mol. Endocrinol. 10:1996;967-978.
9. Cole T.J., Blendy J.A., Monaghan A.P., Krieglstein K., Schmid W., Aguzzi A., Fantuzzi G., Hummler E., Unsicker K., Schütz G. Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev. 9:1995;1608-1621.
10. Dahlman-Wright K., Wright A., Gustafsson J.A., Carlstedt Duke J. Interaction of the glucocorticoid receptor DNA-binding domain with DNA as a dimer is mediated by a short segment of five amino acids. J. Biol. Chem. 266:1991;3107-3112.
11. Drouin J., Sun Y.L., Chamberland M., Gauthier Y., De L.A., Nemer M., Schmidt T.J. Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene. Embo J. 12:1993;145-156.
12. Fink, G., 1997. Mechanism of negative and positive feedback of steroids in the hypothalamic-pituitary system. In: Bittar, E.E., Bittar, N. (Eds.), Principles of Medical Biology. JAI Press, pp. 29-100.
13. Funder J.W., Pearce P.T., Smith R., Smith A.I. Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science. 242:1988;583-585.
14. Heck S., Bender K., Kullmann M., Göttlicher M., Herrlich P., Cato A.C.B. IκBα independent downregulation of NF-κB activity by glucocorticoid receptor. Embo J. 16:1997;4698-4707.
15. Heck S., Kullmann M., Gast A., Ponta H., Rahmsdorf H.J., Herrlich P., Cato A.C. A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1. Embo J. 13:1994;4087-4095.
16. Helmberg A., Auphan N., Caelles C., Karin M. Glucocorticoid-induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor. Embo J. 14:1995;452-460.
17. Hollenberg S.M., Weinberger C., Ong E.S., Cerelli G., Oro A., Lebo R., Thompson E.B., Rosenfeld M. G., Evans R.M. Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature. 318:1985;635-641.
18. Imai E., Miner J.N., Mitchell J.A., Yamamoto K.R., Granner D.K. Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids. J. Biol. Chem. 268:1993;5353-5356.
19. Jonat C., Rahmsdorf H.J., Park K.K., Cato A.C., Gebel S., Ponta H., Herrlich P. Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell. 62:1990;1189-1204.
20. Kamei Y., Xu L., Heinzel T., Torchia J., Kurokawa R., Gloss B., Lin S.C., Heyman R.A., Rose D.W., Glass C.K., Rosenfeld M.G. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell. 85:1996;403-414.
21. Liu W., Wang J., Sauter N.K., Pearce D. Steroid receptor heterodimerization demonstrated in vitro and in vivo. Proc. Natl. Acad. Sci. USA. 92:1995;12480-12484.
22. Luisi B.F., Xu W.X., Otwinowski Z., Freedman L. P., Yamamoto K.R., Sigler P.B. Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA. Nature. 352:1991;497-505.
23. Mader S., Kumar V., de Verneuil H., Chambon P. Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element. Nature. 338:1989;271-274.
24. Miller, W.L., Blake Tyrrel, J., 1995. The adrenal cortex. In: Felig, P., Baxter, J.D., Frohman, L.A. (Eds.), Endocrinology and Metabolism. McGraw-Hill, New York, pp. 555-711.
25. Murphy E.P., Conneely O.M. Neuroendocrine regulation of the hypothalamic pituitary adrenal axis by the nurr1/nur77 subfamily of nuclear receptors. Mol. Endocrinol. 11:1997;39-47.
26. Reichardt H.M., Kaestner K.H., Tuckermann J., Kretz O., Gass P., Schmid W., Herrlich P., Angel P., Schütz G. DNA binding of the glucocorticoid receptor is not essential for survival. Cell. 93:1998;531-541.
27. Reichardt H.M., Schütz G. Feedback control of glucocorticoid production is established during fetal development. Mol. Med. 2:1996;735-744.
28. Ruppert S., Boshart M., Bosch F.X., Schmid W., Fournier R.E., Schütz G. Two genetically defined trans-acting loci coordinately regulate overlapping sets of liver-specific genes. Cell. 61:1990;895-904.
29. Sakai D.D., Helms S., Carlstedt Duke J., Gustafsson J.A., Rottman F.M., Yamamoto K.R. Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene. Genes Dev. 2:1988;1144-1154.
30. Scheinman R.I., Cogswell P.C., Lofquist A.K., Baldwin A.S. Jr. Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science. 270:1995;283-286.
31. Schüle R., Rangarajan P., Kliewer S., Ransone L.J., Bolado J., Yang N., Verma I.M., Evans R.M. Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell. 62:1990;1217-1226.
32. Seasholtz A.F., Thompson R.C., Douglass J.O. Identification of a cyclic adenosine monophosphate-responsive element in the rat corticotropin-releasing hormone gene. Mol. Endocrinol. 2:1988;1311-1319.
33. Stöcklin E., Wissler M., Gouilleux F., Groner B. Functional interactions between Stat5 and the glucocorticoid receptor. Nature. 383:1996;726-728.
34. Strähle U., Klock G., Schütz G. A DNA sequence of 15 base pairs is sufficient to mediate both glucocorticoid and progesterone induction of gene expression. Proc. Natl. Acad. Sci. USA. 84:1987;7871-7875.
35. Stromstedt P.E., Poellinger L., Gustafsson J.A., Carlstedt Duke J. The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: a potential mechanism for negative regulation. Mol. Cell. Biol. 11:1991;3379-3383.
36. Trapp T., Rupprecht R., Castren M., Reul J.M., Holsboer F. Heterodimerization between mineralocorticoid and glucocorticoid receptor: a new principle of glucocorticoid action in the CNS. Neuron. 13:1994;1457-1462.
37. Wessely O., Deiner E., Beug H., von Lindern M. The glucocorticoid receptor is a key regulator of the decision between self-renewal and differentiation in erythroid progenitors. Embo J. 16:1997;267-280.
38. Yang Yen H.F., Chambard J.C., Sun Y.L., Smeal T., Schmidt T.J., Drouin J., Karin M. Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell. 62:1990;1205-1215.