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Volumn 130, Issue 2, 2000, Pages 289-298

Glucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor-dependent, transcription-independent mechanism

Author keywords

A549 cells; Annexin 1; Epidermal growth factor; Epidermal growth factor receptors; Glucocorticoids; Grb2; Lipocortin 1; Mitogen activated protein kinase

Indexed keywords

ARACHIDONIC ACID; DACTINOMYCIN; DEXAMETHASONE; EPIDERMAL GROWTH FACTOR RECEPTOR; GLUCOCORTICOID; GROWTH FACTOR RECEPTOR; MIFEPRISTONE; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDE; PHOSPHOLIPASE A2; PHOSPHOPROTEIN; PROTEIN P21; PROTEIN TYROSINE KINASE; RAF PROTEIN; SERINE;

EID: 0034059188     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703272     Document Type: Article
Times cited : (281)

References (42)
  • 1
    • 0025832605 scopus 로고
    • Multiple components in an epidermal growth factor-stimulated protein kinase cascade
    • AHN, N.G., SEGER, R., BRATLIEN, R.L., DILTZ, C.D., TONKS, N.K. & E.G. KREBS. (1991). Multiple components in an epidermal growth factor-stimulated protein kinase cascade. J. Biol. Chem., 266, 4220-4227.
    • (1991) J. Biol. Chem. , vol.266 , pp. 4220-4227
    • Ahn, N.G.1    Seger, R.2    Bratlien, R.L.3    Diltz, C.D.4    Tonks, N.K.5    Krebs, E.G.6
  • 2
    • 0030026713 scopus 로고    scopus 로고
    • Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids
    • BAMBERGER, C.M., SCHULTE, H.M. & CHROUSOS, G.P. (1996). Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids. Endocrin. Rev., 17, 245-261.
    • (1996) Endocrin. Rev. , vol.17 , pp. 245-261
    • Bamberger, C.M.1    Schulte, H.M.2    Chrousos, G.P.3
  • 3
    • 0031453248 scopus 로고    scopus 로고
    • The Jun kinase/stress-activated protein kinase pathway is required for epidermal growth factor stimulation of growth of human A549 lung carcinoma cells
    • BOST, F., MCKAY, R., DEAN, N. & MERCOLA, D. (1997). The JUN kinase/stress-activated protein kinase pathway is required for epidermal growth factor stimulation of growth of human A549 lung carcinoma cells. J. Biol. Chem., 272, 33422-33429.
    • (1997) J. Biol. Chem. , vol.272 , pp. 33422-33429
    • Bost, F.1    McKay, R.2    Dean, N.3    Mercola, D.4
  • 4
    • 0029875326 scopus 로고    scopus 로고
    • Stress and the neuroendocrine-immune axis: The pivotal role of glucocorticoids and lipocortin 1
    • BUCKINGHAM, J.C. (1996). Stress and the neuroendocrine-immune axis: the pivotal role of glucocorticoids and lipocortin 1. Br. J. Pharmacol., 118, 1-19.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 1-19
    • Buckingham, J.C.1
  • 5
    • 0028245832 scopus 로고
    • A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in ras activation in T cells
    • BUDAY, L., EGAN, S.E., VICIANA, P.R., CANTRELL, D.A. & DOWNWARD, J. (1994). A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in Ras activation in T cells. J. Biol. Chem., 269, 9019-9023.
    • (1994) J. Biol. Chem. , vol.269 , pp. 9019-9023
    • Buday, L.1    Egan, S.E.2    Viciana, P.R.3    Cantrell, D.A.4    Downward, J.5
  • 6
    • 0031455626 scopus 로고    scopus 로고
    • Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway
    • CAELLES, C., GONZALEZ-SANCHO, J. & MUNOZ, A. (1997). Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway. Genes Dev., 11, 3351-3364.
    • (1997) Genes Dev. , vol.11 , pp. 3351-3364
    • Caelles, C.1    Gonzalez-Sancho, J.2    Munoz, A.3
  • 7
    • 0031907233 scopus 로고    scopus 로고
    • Inhibitory effect of peptides derived from the N-terminus of lipocortin 1 on arachidonic acid release and proliferation in the A549 cell line: Identification of E-Q-E-Y-V as a crucial component
    • CROXTALL, J.D., CHOUDHURY, Q. & FLOWER, R.J. (1998). Inhibitory effect of peptides derived from the N-terminus of lipocortin 1 on arachidonic acid release and proliferation in the A549 cell line: identification of E-Q-E-Y-V as a crucial component. Br. J. Pharmacol., 123, 975-983.
    • (1998) Br. J. Pharmacol. , vol.123 , pp. 975-983
    • Croxtall, J.D.1    Choudhury, Q.2    Flower, R.J.3
  • 9
    • 0029113114 scopus 로고
    • Lipocortin 1 and the control of arachidonic acid release in cell signalling
    • CROXTALL, J.D., CHOUDHURY, Q., TOKUMOTO, H. & FLOWER, R.J. (1995). Lipocortin 1 and the control of arachidonic acid release in cell signalling. Biochem. Pharmacol., 50, 465-474.
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 465-474
    • Croxtall, J.D.1    Choudhury, Q.2    Tokumoto, H.3    Flower, R.J.4
  • 10
    • 0026607559 scopus 로고
    • Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line
    • CROXTALL, J.D. & FLOWER, R.J. (1992). Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line. Proc. Natl. Acad. Sci. U.S.A., 89, 3571-3575.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 3571-3575
    • Croxtall, J.D.1    Flower, R.J.2
  • 11
    • 0028037199 scopus 로고
    • Antisense oligonucleotides to human lipocortin-1 inhibit glucocorticoid-induced inhibition of A549 cell growth and eicosanoid release
    • CROXTALL, J.D. & FLOWER, R.J. (1994). Antisense oligonucleotides to human lipocortin-1 inhibit glucocorticoid-induced inhibition of A549 cell growth and eicosanoid release. Biochem. Pharmacol., 48, 1729-1734.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 1729-1734
    • Croxtall, J.D.1    Flower, R.J.2
  • 12
    • 0027299768 scopus 로고
    • N-terminal peptide fragments of lipocortin-1 inhibit A549 cell growth and block EGF-induced stimulation of proliferation
    • CROXTALL, J.D., WAHEED, S., CHOUDHURY, Q., ANAND, R. & FLOWER, R.J. (1993). N-terminal peptide fragments of lipocortin-1 inhibit A549 cell growth and block EGF-induced stimulation of proliferation. Int. J. Cancer, 54, 153-158.
    • (1993) Int. J. Cancer , vol.54 , pp. 153-158
    • Croxtall, J.D.1    Waheed, S.2    Choudhury, Q.3    Anand, R.4    Flower, R.J.5
  • 13
    • 0025849158 scopus 로고
    • Localization of the 90 kDa heat shock protein binding site within the hormone binding domain of the glucocorticoid receptor by peptide competition
    • DALMAN, F.C., SCHERRER, L.C., TAYLOR, L.P., AKIL, H. & PRATT, W.B. (1991). Localization of the 90 kDa heat shock protein binding site within the hormone binding domain of the glucocorticoid receptor by peptide competition. J. Biol. Chem., 266, 3482-3490.
    • (1991) J. Biol. Chem. , vol.266 , pp. 3482-3490
    • Dalman, F.C.1    Scherrer, L.C.2    Taylor, L.P.3    Akil, H.4    Pratt, W.B.5
  • 16
  • 17
    • 0031757167 scopus 로고    scopus 로고
    • Heat shock protein90-dependent (geldanamycin-inhibited) movement of the glucocorticoid receptor through the cytoplasm to the nucleus requires intact cytoskeleton
    • GALIGNIANA, M.D., SCRUGGS, J.L., HERRINGTON, J., WELSH, M.J., CARTER-SU, C., HOUSLEY, P.R. & PRATT, W.B. (1998). Heat shock protein90-dependent (geldanamycin-inhibited) movement of the glucocorticoid receptor through the cytoplasm to the nucleus requires intact cytoskeleton. Mol. Endocrinol., 12, 1903-1913.
    • (1998) Mol. Endocrinol. , vol.12 , pp. 1903-1913
    • Galigniana, M.D.1    Scruggs, J.L.2    Herrington, J.3    Welsh, M.J.4    Carter-Su, C.5    Housley, P.R.6    Pratt, W.B.7
  • 18
    • 0030013412 scopus 로고    scopus 로고
    • Evidence for specific annexin I-binding proteins on human monocytes
    • GOULDING, N.J., PAN, L., K. WARDWELL, K., GUYRE, V.C. & GUYRE, P.M. (1996). Evidence for specific annexin I-binding proteins on human monocytes. Biochem. J., 316, 593-597.
    • (1996) Biochem. J. , vol.316 , pp. 593-597
    • Goulding, N.J.1    Pan, L.2    K Wardwell, K.3    Guyre, V.C.4    Guyre, P.M.5
  • 19
    • 0030029143 scopus 로고    scopus 로고
    • Discovery of a novel, potent, and src-family-selective tyrosine kinase inhibitor: Study of Lck- and Fyn-dependent T cell activation
    • HANKE, J.H., GARDNER, J.P., DOW, R.L., CHANGELIAN, P.S., BRISSETTE, W.H., WERINGER, E.J., POLLOK, B.A. & CONNELLY, P.A. (1996). Discovery of a novel, potent, and src-family-selective tyrosine kinase inhibitor: study of Lck-and Fyn-dependent T cell activation. J. Biol. Chem., 271, 695-701.
    • (1996) J. Biol. Chem. , vol.271 , pp. 695-701
    • Hanke, J.H.1    Gardner, J.P.2    Dow, R.L.3    Changelian, P.S.4    Brissette, W.H.5    Weringer, E.J.6    Pollok, B.A.7    Connelly, P.A.8
  • 20
    • 0027934108 scopus 로고
    • A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1
    • HECK, S., KULLMANN, M., GAST, A., PONTA, H., RAHMSDORF, H.J., HERRLICH, P. & CATO, A.C.B. (1994). A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1. EMBO J., 13, 4087-4095.
    • (1994) EMBO J. , vol.13 , pp. 4087-4095
    • Heck, S.1    Kullmann, M.2    Gast, A.3    Ponta, H.4    Rahmsdorf, H.J.5    Herrlich, P.6    Cato, A.C.B.7
  • 23
    • 0023708269 scopus 로고
    • Lipocortins 1 and 2 as substrates for the insulin receptor kinase in rat liver
    • KARASIK, A., PEPINSKY, R.B., SHOELSON, S.E. & KAHN, C.R. (1988). Lipocortins 1 and 2 as substrates for the insulin receptor kinase in rat liver. J. Biol. Chem., 263, 11862-11867.
    • (1988) J. Biol. Chem. , vol.263 , pp. 11862-11867
    • Karasik, A.1    Pepinsky, R.B.2    Shoelson, S.E.3    Kahn, C.R.4
  • 24
    • 0032488810 scopus 로고    scopus 로고
    • Dexamethasone rapidly induces a novel ras superfamily member-related gene in AtT-20 cells
    • KEMPPANIEN, R.J. & BEHREND, E.N. (1998). Dexamethasone rapidly induces a novel ras superfamily member-related gene in AtT-20 cells. J. Biol. Chem., 273, 3129-3131.
    • (1998) J. Biol. Chem. , vol.273 , pp. 3129-3131
    • Kemppanien, R.J.1    Behrend, E.N.2
  • 29
    • 0030783255 scopus 로고    scopus 로고
    • The 66-kDa She isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway
    • OKADA, S., KAO, A.W., CERESA, B.P., BLAIKIE, P., MARGOLIS, B. & PESSIN, J.E. (1997). The 66-kDa She isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway. J. Biol. Chem., 272, 28042-28049.
    • (1997) J. Biol. Chem. , vol.272 , pp. 28042-28049
    • Okada, S.1    Kao, A.W.2    Ceresa, B.P.3    Blaikie, P.4    Margolis, B.5    Pessin, J.E.6
  • 30
    • 0022527616 scopus 로고
    • Epidermal growth factor-dependent phosphorylation of lipocortin
    • PEPINSKY, R.B. & SINCLAIR, L.K. (1986). Epidermal growth factor-dependent phosphorylation of lipocortin. Nature, 321, 81-85.
    • (1986) Nature , vol.321 , pp. 81-85
    • Pepinsky, R.B.1    Sinclair, L.K.2
  • 31
    • 0031895351 scopus 로고    scopus 로고
    • The hsp90-based chaperone system: Involvement in signal transduction from a variety of hormone and growth factor receptors
    • PRATT, W.B. (1998). The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors. Proc. Soc. Exp. Biol. Med., 217, 420-434.
    • (1998) Proc. Soc. Exp. Biol. Med. , vol.217 , pp. 420-434
    • Pratt, W.B.1
  • 32
    • 0018673506 scopus 로고
    • Transformation by Rous sarcoma virus: Effect of src gene expression on the synthesis and phosphorylation of cellular polypeptides
    • RADKE, K. & MARTIN, G.S. (1979). Transformation by Rous sarcoma virus: effect of src gene expression on the synthesis and phosphorylation of cellular polypeptides. Proc. Natl. Acad. Sci. U.S.A., 76, 5212-5216.
    • (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.76 , pp. 5212-5216
    • Radke, K.1    Martin, G.S.2
  • 34
    • 0023654670 scopus 로고
    • 2+-dependent phospholipid binding and phosphorylation of lipocortin 1
    • 2+-dependent phospholipid binding and phosphorylation of lipocortin 1. J. Biol. Chem., 262, 6931-6937.
    • (1987) J. Biol. Chem. , vol.262 , pp. 6931-6937
    • Schlaepfer, D.D.1    Haigler, H.T.2
  • 35
    • 0023951842 scopus 로고
    • In vitro protein kinase C phosphorylation sites of placental lipocortin
    • SCHLAEPFER, D.D. & HAIGLER, H.T. (1988). In vitro protein kinase C phosphorylation sites of placental lipocortin. Biochemistry, 27, 4253-4258.
    • (1988) Biochemistry , vol.27 , pp. 4253-4258
    • Schlaepfer, D.D.1    Haigler, H.T.2
  • 36
    • 0029861906 scopus 로고    scopus 로고
    • The hepatocyte growth factor receptor kinase-mediated phosphorylation of lipocortin-1 transduces the proliferating signal of the hepatocyte growth factor
    • SKOUTERIS, G.G. & SCHRODER, C.H. (1996). The hepatocyte growth factor receptor kinase-mediated phosphorylation of lipocortin-1 transduces the proliferating signal of the hepatocyte growth factor. J. Biol. Chem., 271, 27266-27273.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27266-27273
    • Skouteris, G.G.1    Schroder, C.H.2
  • 37
    • 0028895156 scopus 로고
    • SH2 and SH3 domains: Potential targets for anti-cancer drug design
    • SMITHGALL, T.E. (1995). SH2 and SH3 domains: potential targets for anti-cancer drug design. J. Pharmacol. Toxicol. Methods, 34, 125-132.
    • (1995) J. Pharmacol. Toxicol. Methods , vol.34 , pp. 125-132
    • Smithgall, T.E.1
  • 39
    • 0021956465 scopus 로고
    • Phosphorylation of a chromaffin granule-binding protein by protein kinase C
    • SUMMERS, T.A. & CREUTZ, C.E. (1985). Phosphorylation of a chromaffin granule-binding protein by protein kinase C. J. Biol. Chem., 260, 2437-2443.
    • (1985) J. Biol. Chem. , vol.260 , pp. 2437-2443
    • Summers, T.A.1    Creutz, C.E.2
  • 40
    • 0030999877 scopus 로고    scopus 로고
    • Aldosterone and dexamethasone stimulate calcineurin activity through a transcription-independent mechanism involving steroid receptor-associated heat shock proteins
    • TUMLIN, J.A., LEA, J.P., SWANSON, C.E., SMITH, C.L., EDGE, S.S. & SOMEREN, J.S. (1997). Aldosterone and dexamethasone stimulate calcineurin activity through a transcription-independent mechanism involving steroid receptor-associated heat shock proteins. J. Clin. Invest., 99, 1217-1223.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1217-1223
    • Tumlin, J.A.1    Lea, J.P.2    Swanson, C.E.3    Smith, C.L.4    Edge, S.S.5    Someren, J.S.6
  • 41
    • 0026520936 scopus 로고
    • Adrenalectomy decreases lipocortin-1 messenger ribonucleic acid and tissue protein content in rats
    • VISHWANATH, B.S., FREY, F.J., BRADBURY, M.J., DALLMAN, M.F. & FREY, B.M. (1992). Adrenalectomy decreases lipocortin-1 messenger ribonucleic acid and tissue protein content in rats. Endocrinology, 130, 585-591.
    • (1992) Endocrinology , vol.130 , pp. 585-591
    • Vishwanath, B.S.1    Frey, F.J.2    Bradbury, M.J.3    Dallman, M.F.4    Frey, B.M.5
  • 42
    • 0029973294 scopus 로고    scopus 로고
    • Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells
    • WHITESELL, L. & COOK, P. (1996). Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells. Mol. Endocrinol., 10, 705-712.
    • (1996) Mol. Endocrinol. , vol.10 , pp. 705-712
    • Whitesell, L.1    Cook, P.2


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