Modification of endoplasmic reticulum Ca2+ stores by select oxidants produces changes reminiscent of those in cells from patients with Alzheimer disease

Free Radical Biology and Medicine

Volumn 39, Issue 8, 2005, Pages 979-989

  Huang, Hsueh Meei ^a   Chen, Huan Lian ^a   Xu, Hui ^a   Gibson, Gary E ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Alzheimer's disease; Endoplasmic reticulum Ca2+ stores; Fibroblasts; Free radicals; Oxidants; Oxidative stress; Presenilin 1; Reactive oxygen species

Indexed keywords

4 AMINO 5 METHYLAMINO 2',7' DIFLUOROFLUORESCEIN DIACETATE; 6 CARBOXY 2',7' DICHLORODIHYDROFLUORESCEIN DIACETATE BIS(ACETOXYMETHYL ESTER); BOMBESIN; CALCIUM ION; FLUORESCEIN DERIVATIVE; FLUORESCENT DYE; LINSIDOMINE; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; OXIDIZING AGENT; PRESENILIN 1; REACTIVE OXYGEN METABOLITE; TERT BUTYL HYDROPEROXIDE; UNCLASSIFIED DRUG; XANTHINE OXIDASE;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM METABOLISM; CELL FUNCTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FEMALE; FIBROBLAST CULTURE; GENE MUTATION; HUMAN; HUMAN CELL; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL;

ALZHEIMER DISEASE; BOMBESIN; CALCIUM; CELLS, CULTURED; ENDOPLASMIC RETICULUM; FIBROBLASTS; FLUORESCEINS; HUMANS; NITRIC OXIDE; OXIDANTS; REACTIVE OXYGEN SPECIES; TERT-BUTYLHYDROPEROXIDE;

MUS MUSCULUS;

EID: 25144495076     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2005.05.017     Document Type: Article

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