메뉴 건너뛰기




Volumn 6, Issue 6, 2005, Pages 585-601

Sarcomas and pharmacogenetics

Author keywords

Anthracyclines; Cisplatin; ET 743; Imatinib; Methotrexate; Pharmacogenetics; Sarcoma

Indexed keywords

ALKYLATING AGENT; ANTHRACYCLINE DERIVATIVE; BLEOMYCIN; CARRIER PROTEIN; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOCHROME P450; CYTOCHROME P450 2C9; DACARBAZINE; DACTINOMYCIN; DIHYDROFOLATE REDUCTASE; DOXORUBICIN; EPIRUBICIN; FOLIC ACID; GEMCITABINE; GLUTATHIONE TRANSFERASE; GLYCOPROTEIN P; IFOSFAMIDE; IMATINIB; MESNA; METHOTREXATE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); PACLITAXEL; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; STEM CELL FACTOR; TEMOZOLOMIDE; THYMIDYLATE SYNTHASE; TROFOSFAMIDE; UNINDEXED DRUG; VINCRISTINE;

EID: 25144454121     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/14622416.6.6.585     Document Type: Review
Times cited : (6)

References (104)
  • 1
    • 0036270843 scopus 로고    scopus 로고
    • ET-743: The US experience in sarcomas of soft tissues
    • Demetri GD: ET-743: the US experience in sarcomas of soft tissues. Anticancer Drugs 13(Suppl. 1), S7-S9 (2002).
    • (2002) Anticancer Drugs , vol.13 , Issue.SUPPL. 1
    • Demetri, G.D.1
  • 2
    • 0027280571 scopus 로고
    • An intergroup Phase III randomized study of doxorubicin and dacarbazine with or without ifosfamide and mesna in advanced soft tissue and bone sarcomas
    • Antman K, Crowley J, Balcerzak SP et al.: An intergroup Phase III randomized study of doxorubicin and dacarbazine with or without ifosfamide and mesna in advanced soft tissue and bone sarcomas. J. Clin. Oncol. 11(7), 1276-1285 (1993).
    • (1993) J. Clin. Oncol. , vol.11 , Issue.7 , pp. 1276-1285
    • Antman, K.1    Crowley, J.2    Balcerzak, S.P.3
  • 3
    • 0023142209 scopus 로고
    • Cyclophosphamide versus ifosfamide: Final report of a randomized Phase II trial in adult soft tissue sarcomas
    • Bramwell VH, Mouridsen HT, Santoro A et al.: Cyclophosphamide versus ifosfamide: final report of a randomized Phase II trial in adult soft tissue sarcomas. Eur. J. Cancer Clin. Oncol. 23(3), 311-321 (1987).
    • (1987) Eur. J. Cancer Clin. Oncol. , vol.23 , Issue.3 , pp. 311-321
    • Bramwell, V.H.1    Mouridsen, H.T.2    Santoro, A.3
  • 4
    • 0027256397 scopus 로고
    • Randomized comparison of doxorubicin alone versus ifosfamide plus doxorubicin or mitomycin, doxorubicin, and cisplatin against advanced soft tissue sarcomas
    • Edmonson JH, Ryan LM, Blum RH et al.: Randomized comparison of doxorubicin alone versus ifosfamide plus doxorubicin or mitomycin, doxorubicin, and cisplatin against advanced soft tissue sarcomas. J. Clin. Oncol. 11 (7), 1269-1275 (1993).
    • (1993) J. Clin. Oncol. , vol.11 , Issue.7 , pp. 1269-1275
    • Edmonson, J.H.1    Ryan, L.M.2    Blum, R.H.3
  • 5
    • 0017704418 scopus 로고
    • Dose response evaluation of adriamycin in human neoplasia
    • O'Bryan RM, Baker LH, Gottlieb JE et al.: Dose response evaluation of adriamycin in human neoplasia. Cancer 39(5), 1940-1948 (1977).
    • (1977) Cancer , vol.39 , Issue.5 , pp. 1940-1948
    • O'Bryan, R.M.1    Baker, L.H.2    Gottlieb, J.E.3
  • 6
    • 0018880740 scopus 로고
    • Cyclophosphamide, vincristine, adriamycin, and DTIC (CYVADIC) combination chemotherapy for the treatment of advanced sarcomas
    • Yap BS, Baker LH, Sinkovics JG et al.: Cyclophosphamide, vincristine, adriamycin, and DTIC (CYVADIC) combination chemotherapy for the treatment of advanced sarcomas. Cancer Treat. Rep. 64(1), 93-98 (1980).
    • (1980) Cancer Treat. Rep. , vol.64 , Issue.1 , pp. 93-98
    • Yap, B.S.1    Baker, L.H.2    Sinkovics, J.G.3
  • 7
    • 0035003544 scopus 로고    scopus 로고
    • A randomised Phase II study on neo-adjuvant chemotherapy for 'high-risk' adult soft-tissue sarcoma
    • Gortzak F, Azzarelli A, Buesa J et al.: A randomised Phase II study on neo-adjuvant chemotherapy for 'high-risk' adult soft-tissue sarcoma. Eur. J. Cancer 37(9), 1096-1103 (2001).
    • (2001) Eur. J. Cancer , vol.37 , Issue.9 , pp. 1096-1103
    • Gortzak, F.1    Azzarelli, A.2    Buesa, J.3
  • 8
    • 0030912403 scopus 로고    scopus 로고
    • High-dose ifosfamide in bone and soft tissue sarcomas: Results of Phase II and pilot studies - Dose-response and schedule dependence
    • Patel SR, Vadhan-Raj S, Papadopolous N C et al.: High-dose ifosfamide in bone and soft tissue sarcomas: results of Phase II and pilot studies - dose-response and schedule dependence. J. Clin. Oncol. 15(6), 2378-2384 (1997).
    • (1997) J. Clin. Oncol. , vol.15 , Issue.6 , pp. 2378-2384
    • Patel, S.R.1    Vadhan-Raj, S.2    Papadopolous, N.C.3
  • 9
    • 0031022801 scopus 로고    scopus 로고
    • Treatment of nonmecastatic osteosarcoma of the extremity with preoperative and postoperative chemotherapy: A report from the Children's Cancer Group
    • Provisor AJ, Ettinger LJ, Nachman JB et al.: Treatment of nonmecastatic osteosarcoma of the extremity with preoperative and postoperative chemotherapy: a report from the Children's Cancer Group. J. Clin. Oncol. 15(1), 76-84 (1997).
    • (1997) J. Clin. Oncol. , vol.15 , Issue.1 , pp. 76-84
    • Provisor, A.J.1    Ettinger, L.J.2    Nachman, J.B.3
  • 10
    • 10744233986 scopus 로고    scopus 로고
    • Adjuvant therapy of osteosarcoma - A Phase II trial: Southwest Oncology Group study 9139
    • Zalupski MM, Rankin C, Ryan JR et al.: Adjuvant therapy of osteosarcoma - a Phase II trial: Southwest Oncology Group study 9139. Cancer 100(4), 818-825 (2004).
    • (2004) Cancer , vol.100 , Issue.4 , pp. 818-825
    • Zalupski, M.M.1    Rankin, C.2    Ryan, J.R.3
  • 11
    • 13444253743 scopus 로고    scopus 로고
    • High-dose ifosfamide in relapsed pediatric osteosarcoma: Therapeutic effects and renal toxicity
    • Berrak SG, Pearson M, Berberoglu S, Ilhan IE, Jaffe N: High-dose ifosfamide in relapsed pediatric osteosarcoma: therapeutic effects and renal toxicity. Pediatr. Blood Cancer 44(3), 215-219 (2005).
    • (2005) Pediatr. Blood Cancer , vol.44 , Issue.3 , pp. 215-219
    • Berrak, S.G.1    Pearson, M.2    Berberoglu, S.3    Ilhan, I.E.4    Jaffe, N.5
  • 12
    • 14644406812 scopus 로고    scopus 로고
    • Ifosfamide, carboplatin, and etoposide (ICE) reinduction chemotherapy in a large cohort of children and adolescents with recurrent/refractory sarcoma: The Children's Cancer Group (CCG) experience
    • Van Winkle P, Angiolillo A, Krailo M et al.: Ifosfamide, carboplatin, and etoposide (ICE) reinduction chemotherapy in a large cohort of children and adolescents with recurrent/refractory sarcoma: the Children's Cancer Group (CCG) experience. Pediatr. Blood Cancer 44(4), 338-347 (2005).
    • (2005) Pediatr. Blood Cancer , vol.44 , Issue.4 , pp. 338-347
    • Van Winkle, P.1    Angiolillo, A.2    Krailo, M.3
  • 13
    • 0035282058 scopus 로고    scopus 로고
    • Adjuvant chemotherapy for adult soft tissue sarcomas of the extremities and girdles: Results of the Italian randomized cooperative trial
    • Frustaci S, Gherlinzoni F, De Paoli A et al.: Adjuvant chemotherapy for adult soft tissue sarcomas of the extremities and girdles: results of the Italian randomized cooperative trial. J. Clin. Oncol. 19(5), 1238-1247 (2001).
    • (2001) J. Clin. Oncol. , vol.19 , Issue.5 , pp. 1238-1247
    • Frustaci, S.1    Gherlinzoni, F.2    De Paoli, A.3
  • 14
    • 2342461682 scopus 로고    scopus 로고
    • Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy
    • Garcia-Carbonero R, Supko JG, Manola J et al.: Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy. J. Clin. Oncol. 22(8), 1480-1490 (2004).
    • (2004) J. Clin. Oncol. , vol.22 , Issue.8 , pp. 1480-1490
    • Garcia-Carbonero, R.1    Supko, J.G.2    Manola, J.3
  • 15
    • 4544227216 scopus 로고    scopus 로고
    • Dose effect of imatinib (IM) in patients (pts) with metastatic GIST - A Phase III sarcoma group study S0033
    • Proceedings of the Annual Meeting of
    • Rankin C, von Mehren M: Dose effect of imatinib (IM) in patients (pts) with metastatic GIST - a Phase III sarcoma group study S0033. Proceedings of the Annual Meeting of Am. Soc. Clin. Oncol. (2004).
    • (2004) Am. Soc. Clin. Oncol.
    • Rankin, C.1    von Mehren, M.2
  • 16
    • 0142121411 scopus 로고    scopus 로고
    • Imatinib mesylate (STI-571 Glivec, Gleevec) is an active agent for gastrointestinal stromal tumours, but does not yield responses in other soft-tissue sarcomas that are unselected for a molecular target. Results from an EORTC Soft Tissue and Bone Sarcoma Group phase II study
    • Verweij J, van Oosterom A, Blay JY et al.: Imatinib mesylate (STI-571 Glivec, Gleevec) is an active agent for gastrointestinal stromal tumours, but does not yield responses in other soft-tissue sarcomas that are unselected for a molecular target. Results from an EORTC Soft Tissue and Bone Sarcoma Group phase II study. Eur. J. Cancer 39(14), 2006-2011 (2003).
    • (2003) Eur. J. Cancer , vol.39 , Issue.14 , pp. 2006-2011
    • Verweij, J.1    van Oosterom, A.2    Blay, J.Y.3
  • 17
    • 0003222972 scopus 로고    scopus 로고
    • High incidence of durable responses induced by imatinib mesylate (Gleevec) in patients with unresectable and metastatic gastrointestinal stromal tumors (GISTs)
    • Proceedings of the Annual Meeting of
    • von Mehren M: High incidence of durable responses induced by imatinib mesylate (Gleevec) in patients with unresectable and metastatic gastrointestinal stromal tumors (GISTs). Proceedings of the Annual Meeting of Am. Soc. Clin. Oncol. (2002).
    • (2002) Am. Soc. Clin. Oncol.
    • von Mehren, M.1
  • 18
    • 2942619994 scopus 로고    scopus 로고
    • Indications for imatinib mesylate therapy and clinical management
    • Guilhot F: Indications for imatinib mesylate therapy and clinical management. Oncologist 9(3), 271-281 (2004).
    • (2004) Oncologist , vol.9 , Issue.3 , pp. 271-281
    • Guilhot, F.1
  • 19
    • 20844433223 scopus 로고    scopus 로고
    • Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: Randomised trial
    • Verweij J, Casali PG, Zalcberg J JY et al.: Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial. Lancet 364(9440), 1127-1134 (2004).
    • (2004) Lancet , vol.364 , Issue.9440 , pp. 1127-1134
    • Verweij, J.1    Casali, P.G.2    Zalcberg, J.J.Y.3
  • 20
    • 17644374218 scopus 로고    scopus 로고
    • Warfarin: A case history in pharmacogenetics
    • Hall AM, Wilkins MR: Warfarin: a case history in pharmacogenetics. Heart 91(5), 563-564 (2005).
    • (2005) Heart , vol.91 , Issue.5 , pp. 563-564
    • Hall, A.M.1    Wilkins, M.R.2
  • 21
    • 2342459714 scopus 로고    scopus 로고
    • Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan
    • Innocenti F, Undevia SD, Iyer L et al.: Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. J. Clin. Oncol. 22(8), 1382-1388 (2004).
    • (2004) J. Clin. Oncol. , vol.22 , Issue.8 , pp. 1382-1388
    • Innocenti, F.1    Undevia, S.D.2    Iyer, L.3
  • 22
    • 0037421590 scopus 로고    scopus 로고
    • Pharmacogenomics - Drug disposition, drug targets, and side effects
    • Evans WE, McLeod HL: Pharmacogenomics - drug disposition, drug targets, and side effects. N. Engl. J. Med. 348(6), 538-549 (2003).
    • (2003) N. Engl. J. Med. , vol.348 , Issue.6 , pp. 538-549
    • Evans, W.E.1    McLeod, H.L.2
  • 24
    • 0742321734 scopus 로고    scopus 로고
    • Human drug metabolising cytochrome P450 enzymes: Properties and polymorphisms
    • Ingelman-Sundberg M: Human drug metabolising cytochrome P450 enzymes: properties and polymorphisms. Naunyn Schmiedebergs Arch. Pharmacol. 369(1), 89-104 (2004).
    • (2004) Naunyn Schmiedebergs Arch. Pharmacol. , vol.369 , Issue.1 , pp. 89-104
    • Ingelman-Sundberg, M.1
  • 25
    • 0033951849 scopus 로고    scopus 로고
    • Role of human liver microsomal CYP3A4 and CYP2B6 in catalyzing N-dechloroethylation of cyclophosphamide and ifosfamide
    • Huang Z, Roy P, Waxman DJ: Role of human liver microsomal CYP3A4 and CYP2B6 in catalyzing N-dechloroethylation of cyclophosphamide and ifosfamide. Biochem. Pharmacol. 59(8), 961-972 (2000).
    • (2000) Biochem. Pharmacol. , vol.59 , Issue.8 , pp. 961-972
    • Huang, Z.1    Roy, P.2    Waxman, D.J.3
  • 26
    • 0033051029 scopus 로고    scopus 로고
    • Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles
    • Roy P, Yu LJ, Crespi CL, Waxman DJ: Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles. Drug Metab. Dispos. 27(6), 655-666 (1999).
    • (1999) Drug Metab. Dispos. , vol.27 , Issue.6 , pp. 655-666
    • Roy, P.1    Yu, L.J.2    Crespi, C.L.3    Waxman, D.J.4
  • 27
    • 0034948077 scopus 로고    scopus 로고
    • Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver
    • Lang T, Klein K, Fischer J et al.: Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver. Pharmacogenetics 11(5), 399-415 (2001).
    • (2001) Pharmacogenetics , vol.11 , Issue.5 , pp. 399-415
    • Lang, T.1    Klein, K.2    Fischer, J.3
  • 28
    • 0037252660 scopus 로고    scopus 로고
    • Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation
    • Xie HJ, Yasar U, Lundgren S et al.: Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation. Pharmacogenomics J. 3(1), 53-61 (2003).
    • (2003) Pharmacogenomics J. , vol.3 , Issue.1 , pp. 53-61
    • Xie, H.J.1    Yasar, U.2    Lundgren, S.3
  • 29
    • 0034815451 scopus 로고    scopus 로고
    • A single nucleotide polymorphism of CYP2B6 found in Japanese enhances catalytic activity by autoactivation
    • Ariyoshi N, Miyazaki M, Toide K, Sawamura Y, Kamataki T: A single nucleotide polymorphism of CYP2B6 found in Japanese enhances catalytic activity by autoactivation. Biochem. Biophys. Res. Commun. 281(5), 1256-1260 (2001).
    • (2001) Biochem. Biophys. Res. Commun. , vol.281 , Issue.5 , pp. 1256-1260
    • Ariyoshi, N.1    Miyazaki, M.2    Toide, K.3    Sawamura, Y.4    Kamataki, T.5
  • 30
    • 21244500925 scopus 로고    scopus 로고
    • Directed evolution of mammalian cytochrome P450 2B1: Mutations outside of the active site enhance the metabolism of several substrates, including the anticancer prodrugs cyclophosphamide and ifosfamide
    • Kumar S, Chen CS, Waxman DJ, Halpert JR: Directed evolution of mammalian cytochrome P450 2B1: mutations outside of the active site enhance the metabolism of several substrates, including the anticancer prodrugs cyclophosphamide and ifosfamide. J. Biol. Chem. 280(20), 19569-19575 (2005).
    • (2005) J. Biol. Chem. , vol.280 , Issue.20 , pp. 19569-19575
    • Kumar, S.1    Chen, C.S.2    Waxman, D.J.3    Halpert, J.R.4
  • 31
    • 0038729519 scopus 로고    scopus 로고
    • Bioactivation of cyclophosphamide: The role of polymorphic CYP2C enzymes
    • Griskevicius L, Yasar U, Sandberg M et al.: Bioactivation of cyclophosphamide: the role of polymorphic CYP2C enzymes. Eur. J. Clin. Pharmacol. 59(2), 103-109 (2003).
    • (2003) Eur. J. Clin. Pharmacol. , vol.59 , Issue.2 , pp. 103-109
    • Griskevicius, L.1    Yasar, U.2    Sandberg, M.3
  • 32
    • 0037131892 scopus 로고    scopus 로고
    • CYP2C9 allelic variants: Ethnic distribution and functional significance
    • Xie HG, Prasad HC, Kim RB, Stein CM: CYP2C9 allelic variants: ethnic distribution and functional significance. Adv. Drug Deliv. Rev. 54(10), 1257-1270 (2002).
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , Issue.10 , pp. 1257-1270
    • Xie, H.G.1    Prasad, H.C.2    Kim, R.B.3    Stein, C.M.4
  • 33
    • 12244261584 scopus 로고    scopus 로고
    • Identification and functional characterization of new potentially defective alleles of human CYP2C19
    • Blaisdell J, Mohrenweiser H, Jackson J et al.: Identification and functional characterization of new potentially defective alleles of human CYP2C19. Pharmacogenetics 12(9), 703-711 (2002).
    • (2002) Pharmacogenetics , vol.12 , Issue.9 , pp. 703-711
    • Blaisdell, J.1    Mohrenweiser, H.2    Jackson, J.3
  • 35
    • 15444340367 scopus 로고    scopus 로고
    • A new genetic defect in human CYP2C19: Mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin
    • Ferguson RJ, de Morais SM, Benhamou S et al.: A new genetic defect in human CYP2C19: mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin. J. Pharmacol. Exp. Ther. 284(1), 356-361 (1998).
    • (1998) J. Pharmacol. Exp. Ther. , vol.284 , Issue.1 , pp. 356-361
    • Ferguson, R.J.1    de Morais, S.M.2    Benhamou, S.3
  • 36
    • 0034792584 scopus 로고    scopus 로고
    • Clinical relevance of generic polymorphisms in the human CYP2C subfamily
    • Goldstein JA: Clinical relevance of generic polymorphisms in the human CYP2C subfamily. Br. J. Clin. Pharmacol. 52(4), 349-355 (2001).
    • (2001) Br. J. Clin. Pharmacol. , vol.52 , Issue.4 , pp. 349-355
    • Goldstein, J.A.1
  • 37
    • 0030799414 scopus 로고    scopus 로고
    • Oxidation of cyclophosphamide to 4-hydroxycyclophosphamide and deschloroethylcyclophosphamide in human liver microsomes
    • Ren S, Yang JS, Kalhorn TF, Slattery JT: Oxidation of cyclophosphamide to 4-hydroxycyclophosphamide and deschloroethylcyclophosphamide in human liver microsomes. Cancer Res. 57(19), 4229-4235 (1997).
    • (1997) Cancer Res. , vol.57 , Issue.19 , pp. 4229-4235
    • Ren, S.1    Yang, J.S.2    Kalhorn, T.F.3    Slattery, J.T.4
  • 38
    • 0034959461 scopus 로고    scopus 로고
    • Identification and functional characterization of eight CYP3A4 protein variants
    • Eiselt R, Domanski TL, Zibat A et al.: Identification and functional characterization of eight CYP3A4 protein variants. Pharmacogenetics 11(5), 447-458 (2001).
    • (2001) Pharmacogenetics , vol.11 , Issue.5 , pp. 447-458
    • Eiselt, R.1    Domanski, T.L.2    Zibat, A.3
  • 39
    • 0345643389 scopus 로고    scopus 로고
    • Interindividual differences in hepatic expression of CYP3A4: Relationship to genetic polymorphism in the 5′-upstream regulatory region
    • Westlind A, Lofberg L, Tindberg N, Andersson TB, Ingelman-Sundberg M: Interindividual differences in hepatic expression of CYP3A4: relationship to genetic polymorphism in the 5′-upstream regulatory region. Biochem. Biophys. Res. Commun. 259(1), 201-205 (1999).
    • (1999) Biochem. Biophys. Res. Commun. , vol.259 , Issue.1 , pp. 201-205
    • Westlind, A.1    Lofberg, L.2    Tindberg, N.3    Andersson, T.B.4    Ingelman-Sundberg, M.5
  • 40
    • 0032825907 scopus 로고    scopus 로고
    • Population distribution and effects on drug metabolism of a generic variant in the 5′ promoter region of CYP3A4
    • Ball SE, Scatina J, Kao J et al.: Population distribution and effects on drug metabolism of a generic variant in the 5′ promoter region of CYP3A4. Clin. Pharmacol. Ther. 66(3), 288-294 (1999).
    • (1999) Clin. Pharmacol. Ther. , vol.66 , Issue.3 , pp. 288-294
    • Ball, S.E.1    Scatina, J.2    Kao, J.3
  • 41
    • 22344456708 scopus 로고    scopus 로고
    • Contribution of CYP3A5 to hepatic and renal ifosfamide N-dechloroethylation
    • McCune JS, Risler LJ, Phillips BR et al.: Contribution of CYP3A5 to hepatic and renal ifosfamide N-dechloroethylation. Drug Metab. Dispos. (2005).
    • (2005) Drug Metab. Dispos.
    • McCune, J.S.1    Risler, L.J.2    Phillips, B.R.3
  • 42
    • 0035071598 scopus 로고    scopus 로고
    • Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
    • Kuehl P, Zhang J, Lin Y et al.: Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nature Genet. 27(4), 383-391 (2001).
    • (2001) Nature Genet. , vol.27 , Issue.4 , pp. 383-391
    • Kuehl, P.1    Zhang, J.2    Lin, Y.3
  • 43
    • 18644380835 scopus 로고    scopus 로고
    • Role of cytochrome P450 activity in the fate of anticancer agents and in drug resistance: Focus on tamoxifen, paclitaxel and imatinib metabolism
    • Rochat B: Role of cytochrome P450 activity in the fate of anticancer agents and in drug resistance: focus on tamoxifen, paclitaxel and imatinib metabolism. Clin. Pharmacokinet. 44(4), 349-366 (2005).
    • (2005) Clin. Pharmacokinet. , vol.44 , Issue.4 , pp. 349-366
    • Rochat, B.1
  • 44
    • 0034791777 scopus 로고    scopus 로고
    • Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid
    • Dai D, Zeldin DC, Blaisdell JA et al.: Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid. Pharmacogenetics 11(7), 597-607 (2001).
    • (2001) Pharmacogenetics , vol.11 , Issue.7 , pp. 597-607
    • Dai, D.1    Zeldin, D.C.2    Blaisdell, J.A.3
  • 46
    • 0037350198 scopus 로고    scopus 로고
    • Association between a glutathione S-transferase A1 promoter polymorphism and survival after breast cancer treatment
    • Sweeney C, Ambrosone CB, Joseph L et al.: Association between a glutathione S-transferase A1 promoter polymorphism and survival after breast cancer treatment. Int. J. Cancer 103(6), 810-814 (2003).
    • (2003) Int. J. Cancer , vol.103 , Issue.6 , pp. 810-814
    • Sweeney, C.1    Ambrosone, C.B.2    Joseph, L.3
  • 47
    • 0036497118 scopus 로고    scopus 로고
    • Effect of glutathione S-transferases on the survival of patients with acute myeloid leukaemia
    • Autrup JL, Hokland P, Pedersen L, Autrup H: Effect of glutathione S-transferases on the survival of patients with acute myeloid leukaemia. Eur. J. Pharmacol. 438(1-2), 15-18 (2002).
    • (2002) Eur. J. Pharmacol. , vol.438 , Issue.1-2 , pp. 15-18
    • Autrup, J.L.1    Hokland, P.2    Pedersen, L.3    Autrup, H.4
  • 48
    • 0031784414 scopus 로고    scopus 로고
    • Association of glutathione S-transferase GSTM1 and GSTT1 null genotypes with clinical outcome in epithelial ovarian cancer
    • Howells RE, Redman CW, Dhar KK et al.: Association of glutathione S-transferase GSTM1 and GSTT1 null genotypes with clinical outcome in epithelial ovarian cancer. Clin. Cancer Res. 4(10), 2439-2445 (1998).
    • (1998) Clin. Cancer Res. , vol.4 , Issue.10 , pp. 2439-2445
    • Howells, R.E.1    Redman, C.W.2    Dhar, K.K.3
  • 49
    • 0242490512 scopus 로고    scopus 로고
    • Glutathione S-transferases (GSTT1 and GSTM1) gene deletions in Tunisians: Susceptibility and prognostic implications in breast carcinoma
    • Khedhaier A, Remadi S, Corbex M et al.: Glutathione S-transferases (GSTT1 and GSTM1) gene deletions in Tunisians: susceptibility and prognostic implications in breast carcinoma. Br. J. Cancer 89(8), 1502-1507 (2003).
    • (2003) Br. J. Cancer , vol.89 , Issue.8 , pp. 1502-1507
    • Khedhaier, A.1    Remadi, S.2    Corbex, M.3
  • 50
    • 0035476887 scopus 로고    scopus 로고
    • Polymorphisms in glutathione S-transferases (GSTM1 and GSTT1) and survival after treatment for breast cancer
    • Ambrosone CB, Sweeney C, Coles BF et al.: Polymorphisms in glutathione S-transferases (GSTM1 and GSTT1) and survival after treatment for breast cancer. Cancer Res. 61(19), 7130-7135 (2001).
    • (2001) Cancer Res. , vol.61 , Issue.19 , pp. 7130-7135
    • Ambrosone, C.B.1    Sweeney, C.2    Coles, B.F.3
  • 51
    • 0042305238 scopus 로고    scopus 로고
    • Platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma: Glutathione S-transferase genetic polymorphisms as predictive biomarkers of disease outcome
    • Medeiros R, Pereira D, Afonso N et al.: Platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma: glutathione S-transferase genetic polymorphisms as predictive biomarkers of disease outcome. Int. J. Clin. Oncol. 8(3), 156-161 (2003).
    • (2003) Int. J. Clin. Oncol. , vol.8 , Issue.3 , pp. 156-161
    • Medeiros, R.1    Pereira, D.2    Afonso, N.3
  • 52
    • 5444227259 scopus 로고    scopus 로고
    • Association between aryl hydrocarbon receptor genotype and survival in soft tissue sarcoma
    • Berwick M, Matullo G, Song YS et al.: Association between aryl hydrocarbon receptor genotype and survival in soft tissue sarcoma. J. Clin. Oncol. 22(19), 3997-4001 (2004).
    • (2004) J. Clin. Oncol. , vol.22 , Issue.19 , pp. 3997-4001
    • Berwick, M.1    Matullo, G.2    Song, Y.S.3
  • 53
    • 0034667365 scopus 로고    scopus 로고
    • Association between survival after treatment for breast cancer and glutathione S-transferase P1 Ile105Val polymorphism
    • Sweeney C, McClure GY, Fares MY et al.: Association between survival after treatment for breast cancer and glutathione S-transferase P1 Ile105Val polymorphism. Cancer Res. 60(20), 5621-5624 (2000).
    • (2000) Cancer Res. , vol.60 , Issue.20 , pp. 5621-5624
    • Sweeney, C.1    McClure, G.Y.2    Fares, M.Y.3
  • 54
    • 10844234923 scopus 로고    scopus 로고
    • Genetic polymorphisms in glutathione-S-transferase genes (GSTM1, GSTT1, GSTP1) and survival after chemotherapy for invasive breast carcinoma
    • Yang G, Shu XO, Ruan ZX et al.: Genetic polymorphisms in glutathione-S-transferase genes (GSTM1, GSTT1, GSTP1) and survival after chemotherapy for invasive breast carcinoma. Cancer 103(1), 52-58 (2005).
    • (2005) Cancer , vol.103 , Issue.1 , pp. 52-58
    • Yang, G.1    Shu, X.O.2    Ruan, Z.X.3
  • 55
    • 0037698747 scopus 로고    scopus 로고
    • Polymorphism at the glutathione S-transferase π locus as a risk factor for ifosfamide nephrotoxicity in children
    • Zielinska E, Zubowska M, Bodalski J: Polymorphism at the glutathione S-transferase π locus as a risk factor for ifosfamide nephrotoxicity in children. Pol. Merkuriusz. Lek. 14(82), 295-298 (2003).
    • (2003) Pol. Merkuriusz. Lek. , vol.14 , Issue.82 , pp. 295-298
    • Zielinska, E.1    Zubowska, M.2    Bodalski, J.3
  • 56
    • 0031969286 scopus 로고    scopus 로고
    • Role of glutathione in cisplatin resistance in osteosarcoma cell lines
    • Komiya S, Gebhardt MC, Mangham DC, Inoue A: Role of glutathione in cisplatin resistance in osteosarcoma cell lines. J. Orthop. Res. 16(1), 15-22 (1998).
    • (1998) J. Orthop. Res. , vol.16 , Issue.1 , pp. 15-22
    • Komiya, S.1    Gebhardt, M.C.2    Mangham, D.C.3    Inoue, A.4
  • 57
    • 0031667511 scopus 로고    scopus 로고
    • P-glycoprotein-mediated methotrexate resistance in CCRF-CEM sublines deficient in methotrexate accumulation due to a point mutation in the reduced folate carrier gene
    • Gifford AJ, Kavallaris M, Madafiglio J et al.: P-glycoprotein-mediated methotrexate resistance in CCRF-CEM sublines deficient in methotrexate accumulation due to a point mutation in the reduced folate carrier gene. Int. J. Cancer 78(2), 176-181 (1998).
    • (1998) Int. J. Cancer , vol.78 , Issue.2 , pp. 176-181
    • Gifford, A.J.1    Kavallaris, M.2    Madafiglio, J.3
  • 58
    • 0028645499 scopus 로고
    • Expression of the human multidrug resistance gene (MDR1) and prognostic correlation in human osteogenic sarcoma
    • Imanishi T, Abe Y, Suto R et al.: Expression of the human multidrug resistance gene (MDR1) and prognostic correlation in human osteogenic sarcoma. Tokai J. Exp. Clin. Med. 19(1-2), 39-46 (1994).
    • (1994) Tokai J. Exp. Clin. Med. , vol.19 , Issue.1-2 , pp. 39-46
    • Imanishi, T.1    Abe, Y.2    Suto, R.3
  • 60
    • 0036351238 scopus 로고    scopus 로고
    • Multidrug resistance gene-1 is a useful predictor of paclitaxel-based chemotherapy for patients with ovarian cancer
    • Kamazawa S, Kigawa J, Kanamori Y et al.: Multidrug resistance gene-1 is a useful predictor of paclitaxel-based chemotherapy for patients with ovarian cancer. Gynecol. Oncol. 86(2), 171-176 (2002).
    • (2002) Gynecol. Oncol. , vol.86 , Issue.2 , pp. 171-176
    • Kamazawa, S.1    Kigawa, J.2    Kanamori, Y.3
  • 61
    • 0037443754 scopus 로고    scopus 로고
    • MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models
    • Mahon FX, Belloc F, Lagarde V et al.: MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models. Blood 101(6), 2368-2373 (2003).
    • (2003) Blood , vol.101 , Issue.6 , pp. 2368-2373
    • Mahon, F.X.1    Belloc, F.2    Lagarde, V.3
  • 62
    • 0036206860 scopus 로고    scopus 로고
    • Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: An association between single nucleotide polymorphisms in the 5′-untranslated region and exon 28
    • Itoda M, Saito Y, Soyama A et al.: Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: an association between single nucleotide polymorphisms in the 5′-untranslated region and exon 28. Drug Metab. Dispos. 30(4), 363-364 (2002).
    • (2002) Drug Metab. Dispos. , vol.30 , Issue.4 , pp. 363-364
    • Itoda, M.1    Saito, Y.2    Soyama, A.3
  • 63
    • 0036327586 scopus 로고    scopus 로고
    • Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary
    • Itamochi H, Kigawa J, Sultana H et al.: Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary. Jpn J. Cancer Res. 93(6), 723-728 (2002).
    • (2002) Jpn. J. Cancer Res. , vol.93 , Issue.6 , pp. 723-728
    • Itamochi, H.1    Kigawa, J.2    Sultana, H.3
  • 64
    • 0037317006 scopus 로고    scopus 로고
    • Sequence alterations in the reduced folate carrier are observed in osteosarcoma tumor samples
    • Yang R, Sowers R, Mazza B et al.: Sequence alterations in the reduced folate carrier are observed in osteosarcoma tumor samples. Clin. Cancer Res. 9(2), 837-844 (2003).
    • (2003) Clin. Cancer Res. , vol.9 , Issue.2 , pp. 837-844
    • Yang, R.1    Sowers, R.2    Mazza, B.3
  • 66
    • 0033001234 scopus 로고    scopus 로고
    • Mechanisms of methotrexate resistance in osteosarcoma
    • Guo W, Healey JH, Meyers PA et al.: Mechanisms of methotrexate resistance in osteosarcoma. Clin. Cancer Res. 5(3), 621-627 (1999).
    • (1999) Clin. Cancer Res. , vol.5 , Issue.3 , pp. 621-627
    • Guo, W.1    Healey, J.H.2    Meyers, P.A.3
  • 67
    • 16344368835 scopus 로고    scopus 로고
    • Expression of resistance markers to methotrexate predicts clinical improvement in patients with rheumatoid arthritis
    • Wolf J, Stranzl T, Filipits M et al.: Expression of resistance markers to methotrexate predicts clinical improvement in patients with rheumatoid arthritis. Ann. Rheum. Dis. 64(4), 564-568 (2004).
    • (2004) Ann. Rheum. Dis. , vol.64 , Issue.4 , pp. 564-568
    • Wolf, J.1    Stranzl, T.2    Filipits, M.3
  • 68
    • 0142150087 scopus 로고    scopus 로고
    • Reduced folate carrier protein expression in osteosarcoma: Implications for the prediction of tumor chemosensitivity
    • Ifergan I, Meller I, Issakov J, Assaraf YG: Reduced folate carrier protein expression in osteosarcoma: implications for the prediction of tumor chemosensitivity. Cancer 98(9), 1958-1966 (2003).
    • (2003) Cancer , vol.98 , Issue.9 , pp. 1958-1966
    • Ifergan, I.1    Meller, I.2    Issakov, J.3    Assaraf, Y.G.4
  • 69
    • 0033805360 scopus 로고    scopus 로고
    • A polymorphism (80G>A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia
    • Chango A, Emery-Fillon N, de Courcy GP et al.: A polymorphism (80G>A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia. Mol. Genet. Metab 70(4), 310-315 (2000).
    • (2000) Mol. Genet. Metab , vol.70 , Issue.4 , pp. 310-315
    • Chango, A.1    Emery-Fillon, N.2    de Courcy, G.P.3
  • 70
    • 0037110469 scopus 로고    scopus 로고
    • Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia
    • Laverdiere C, Chiasson S, Costea I, Moghrabi A, Krajinovic M: Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia. Blood 100(10), 3832-3834 (2002).
    • (2002) Blood , vol.100 , Issue.10 , pp. 3832-3834
    • Laverdiere, C.1    Chiasson, S.2    Costea, I.3    Moghrabi, A.4    Krajinovic, M.5
  • 71
    • 9144254448 scopus 로고    scopus 로고
    • Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells
    • Serra M, Reverter-Branch, Maurici D et al.: Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells. Ann. Oncol. 15(1), 151-160 (2004).
    • (2004) Ann. Oncol. , vol.15 , Issue.1 , pp. 151-160
    • Serra, M.1    Reverter-Branch2    Maurici, D.3
  • 72
    • 0024544238 scopus 로고
    • Amplification of a polymorphic dihydrofolate reductase gene expressing an enzyme with decreased binding to methotrexate in a human colon carcinoma cell line, HCT-8R4, resistant to this drug
    • Srimatkandada S, Schweitzer BI, Moroson BA, Dube S, Bertino JR: Amplification of a polymorphic dihydrofolate reductase gene expressing an enzyme with decreased binding to methotrexate in a human colon carcinoma cell line, HCT-8R4, resistant to this drug. J. Biol. Chem. 264(6), 3524-3528 (1989).
    • (1989) J. Biol. Chem. , vol.264 , Issue.6 , pp. 3524-3528
    • Srimatkandada, S.1    Schweitzer, B.I.2    Moroson, B.A.3    Dube, S.4    Bertino, J.R.5
  • 73
    • 0029122937 scopus 로고
    • Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase
    • Horie N, Aiba H, Oguro K, Hojo H, Takeishi K: Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase. Cell Struct. Funct. 20(3), 191-197 (1995).
    • (1995) Cell Struct. Funct. , vol.20 , Issue.3 , pp. 191-197
    • Horie, N.1    Aiba, H.2    Oguro, K.3    Hojo, H.4    Takeishi, K.5
  • 74
    • 0036765747 scopus 로고    scopus 로고
    • Thymidylate synthase: A novel genetic determinant of plasma homocysteine and folate levels
    • Trinh BN, Ong CN, Coetzee GA, Yu MC, Laird PW: Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels. Hum. Genet. 111(3), 299-302 (2002).
    • (2002) Hum. Genet. , vol.111 , Issue.3 , pp. 299-302
    • Trinh, B.N.1    Ong, C.N.2    Coetzee, G.A.3    Yu, M.C.4    Laird, P.W.5
  • 75
    • 0642286407 scopus 로고    scopus 로고
    • Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis
    • Kumagai K, Hiyama K, Oyama T, Maeda H, Kohno N: Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis. Int. J. Mol. Med. 11(5), 593-600 (2003).
    • (2003) Int. J. Mol. Med. , vol.11 , Issue.5 , pp. 593-600
    • Kumagai, K.1    Hiyama, K.2    Oyama, T.3    Maeda, H.4    Kohno, N.5
  • 76
    • 4444376725 scopus 로고    scopus 로고
    • Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis
    • Dervieux T, Furst D, Lein DO et al.: Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis. Arthritis Rheum. 50(9), 2766-2774 (2004).
    • (2004) Arthritis Rheum. , vol.50 , Issue.9 , pp. 2766-2774
    • Dervieux, T.1    Furst, D.2    Lein, D.O.3
  • 77
    • 0037454801 scopus 로고    scopus 로고
    • Effect of methylenetetrahydrofolate reductase 677C>T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients
    • Toffoli G, Russo A, Innocenti F et al.: Effect of methylenetetrahydrofolate reductase 677C>T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients. Int. J. Cancer 103(3), 294-299 (2003).
    • (2003) Int. J. Cancer , vol.103 , Issue.3 , pp. 294-299
    • Toffoli, G.1    Russo, A.2    Innocenti, F.3
  • 79
    • 0642368571 scopus 로고    scopus 로고
    • Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor
    • Heinrich MC, Corless CL, Demetri GD et al.: Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. J. Clin. Oncol. 21(23), 4342-4349 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , Issue.23 , pp. 4342-4349
    • Heinrich, M.C.1    Corless, C.L.2    Demetri, G.D.3
  • 80
    • 20844460619 scopus 로고    scopus 로고
    • A missense mutation in KIT kinase domain 1 correlates with imatinib resistance in gastrointestinal stromal tumors
    • Chen LL, Trent JC, Wu EF et al.: A missense mutation in KIT kinase domain 1 correlates with imatinib resistance in gastrointestinal stromal tumors. Cancer Res. 64(17), 5913-5919 (2004).
    • (2004) Cancer Res. , vol.64 , Issue.17 , pp. 5913-5919
    • Chen, L.L.1    Trent, J.C.2    Wu, E.F.3
  • 81
    • 0035066051 scopus 로고    scopus 로고
    • Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours
    • Hirota S, Nishida T, Isozaki K et al.: Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours. J. Pathol. 193(4), 505-510 (2001).
    • (2001) J. Pathol. , vol.193 , Issue.4 , pp. 505-510
    • Hirota, S.1    Nishida, T.2    Isozaki, K.3
  • 82
    • 21044451716 scopus 로고    scopus 로고
    • Analysis of KIT mutations in sporadic and familial gastrointestinal stromal tumors: Therapeutic implications through protein modeling
    • Tarn C, Merkel E, Canutescu AA et al.: Analysis of KIT mutations in sporadic and familial gastrointestinal stromal tumors: therapeutic implications through protein modeling. Clin. Cancer Res. 11(10), 3668-3677 (2005).
    • (2005) Clin. Cancer Res. , vol.11 , Issue.10 , pp. 3668-3677
    • Tarn, C.1    Merkel, E.2    Canutescu, A.A.3
  • 83
    • 0036907407 scopus 로고    scopus 로고
    • Polymorphisms in DNA repair genes and associations with cancer risk
    • Goode EL, Ulrich CM, Potter JD: Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol. Biomarkers Prev. 11(12), 1513-1530 (2002).
    • (2002) Cancer Epidemiol. Biomarkers Prev. , vol.11 , Issue.12 , pp. 1513-1530
    • Goode, E.L.1    Ulrich, C.M.2    Potter, J.D.3
  • 84
    • 4444256594 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms and outcome in docetaxel-cisplatin-treated advanced non-small-cell lung cancer
    • Isla D, Sarries C, Rosell R et al.: Single nucleotide polymorphisms and outcome in docetaxel-cisplatin-treated advanced non-small-cell lung cancer. Ann. Oncol. 15(8), 1194-1203 (2004).
    • (2004) Ann. Oncol. , vol.15 , Issue.8 , pp. 1194-1203
    • Isla, D.1    Sarries, C.2    Rosell, R.3
  • 85
    • 2342616723 scopus 로고    scopus 로고
    • Association between polymorphisms of ERCC1 and XPD and survival in nonsmall cell lung cancer patients treated with cisplatin combination chemotherapy
    • Ryu JS, Hong YC, Han HS et al.: Association between polymorphisms of ERCC1 and XPD and survival in nonsmall cell lung cancer patients treated with cisplatin combination chemotherapy. Lung Cancer 44(3), 311-316 (2004).
    • (2004) Lung Cancer , vol.44 , Issue.3 , pp. 311-316
    • Ryu, J.S.1    Hong, Y.C.2    Han, H.S.3
  • 86
    • 4143051317 scopus 로고    scopus 로고
    • Excision repair cross-complementation group 1 polymorphism predicts overall survival in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy
    • Zhou W, Gurubhagavatula S, Liu G et al.: Excision repair cross-complementation group 1 polymorphism predicts overall survival in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy. Clin. Cancer Res. 10(15), 4939-4943 (2004).
    • (2004) Clin. Cancer Res. , vol.10 , Issue.15 , pp. 4939-4943
    • Zhou, W.1    Gurubhagavatula, S.2    Liu, G.3
  • 87
    • 10744224719 scopus 로고    scopus 로고
    • Molecular predictors of response to chemotherapy in lung cancer
    • Rosell R, Taron M, Ariza A et al.: Molecular predictors of response to chemotherapy in lung cancer. Semin. Oncol. 31(Suppl. 1), 20-27 (2004).
    • (2004) Semin. Oncol. , vol.31 , Issue.SUPPL. 1 , pp. 20-27
    • Rosell, R.1    Taron, M.2    Ariza, A.3
  • 88
    • 0035874074 scopus 로고    scopus 로고
    • Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways
    • Damia G, Silvestri S, Carrassa L et al.: Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways. Int. J. Cancer 92(4), 583-588 (2001).
    • (2001) Int. J. Cancer , vol.92 , Issue.4 , pp. 583-588
    • Damia, G.1    Silvestri, S.2    Carrassa, L.3
  • 89
    • 17944374027 scopus 로고    scopus 로고
    • Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair
    • Takebayashi Y, Pourquier P, Zimonjic DB et al.: Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair. Nat. Med. 7(8), 961-966 (2001).
    • (2001) Nat. Med. , vol.7 , Issue.8 , pp. 961-966
    • Takebayashi, Y.1    Pourquier, P.2    Zimonjic, D.B.3
  • 90
    • 0142089888 scopus 로고    scopus 로고
    • The combination of yondelis and cisplatin is synergistic against human tumor xenografts
    • D'Incalci M, Colombo T, Ubezio P et al.: The combination of yondelis and cisplatin is synergistic against human tumor xenografts. Eur. J. Cancer 39(13), 1920-1926 (2003).
    • (2003) Eur. J. Cancer , vol.39 , Issue.13 , pp. 1920-1926
    • D'Incalci, M.1    Colombo, T.2    Ubezio, P.3
  • 91
    • 0036270039 scopus 로고    scopus 로고
    • ET-743: More than an innovative mechanism of action
    • Scotto KW: ET-743: more than an innovative mechanism of action. Anticancer Drugs 13(Suppl. 1), S3-S6 (2002).
    • (2002) Anticancer Drugs , vol.13 , Issue.SUPPL. 1
    • Scotto, K.W.1
  • 92
    • 4344567395 scopus 로고    scopus 로고
    • XPD and XRCC1 genetic polymorphisms are prognostic factors in advanced non-small-cell lung cancer patients treated with platinum chemotherapy
    • Gurubhagavatula S, Liu G, Park S et al.: XPD and XRCC1 genetic polymorphisms are prognostic factors in advanced non-small-cell lung cancer patients treated with platinum chemotherapy. J. Clin. Oncol. 22(13), 2594-2601 (2004).
    • (2004) J. Clin. Oncol. , vol.22 , Issue.13 , pp. 2594-2601
    • Gurubhagavatula, S.1    Liu, G.2    Park, S.3
  • 93
    • 16644395637 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in XRCC1 and clinical response to platin-based chemotherapy in advanced non-small cell lung cancer
    • Wang ZH, Miao XP, Tan W, Zhang XR, Xu BH, Lin DX: Single nucleotide polymorphisms in XRCC1 and clinical response to platin-based chemotherapy in advanced non-small cell lung cancer. Ai. Zheng. 23(8), 865-868 (2004).
    • (2004) Ai. Zheng. , vol.23 , Issue.8 , pp. 865-868
    • Wang, Z.H.1    Miao, X.P.2    Tan, W.3    Zhang, X.R.4    Xu, B.H.5    Lin, D.X.6
  • 94
    • 0023176119 scopus 로고
    • Randomized comparison of three adriamycin regimenns for metastatic soft tissue sarcomas
    • Borden EC, Amato DA, Rosenbaum C et al.: Randomized comparison of three adriamycin regimenns for metastatic soft tissue sarcomas. J. Clin. Oncol. 5(6), 840-850 (1987).
    • (1987) J. Clin. Oncol. , vol.5 , Issue.6 , pp. 840-850
    • Borden, E.C.1    Amato, D.A.2    Rosenbaum, C.3
  • 95
    • 0033036527 scopus 로고    scopus 로고
    • Dose-intensive first-line chemotherapy with epirubicin and continuous infusion ifosfamide in adult patients with advanced soft tissue sarcomas: A phase II study
    • Palumbo R, Neumaier C, Cosso M et al.: Dose-intensive first-line chemotherapy with epirubicin and continuous infusion ifosfamide in adult patients with advanced soft tissue sarcomas: a phase II study. Eur. J. Cancer 35(1), 66-72 (1999).
    • (1999) Eur. J. Cancer , vol.35 , Issue.1 , pp. 66-72
    • Palumbo, R.1    Neumaier, C.2    Cosso, M.3
  • 96
    • 0030699251 scopus 로고    scopus 로고
    • Preoperative chemotherapy for stage IIIB extremity soft tissue sarcoma: Long-term results from a single institution
    • Pisters PW, Patel SR, Varma DG et al.: Preoperative chemotherapy for stage IIIB extremity soft tissue sarcoma: long-term results from a single institution. J. Clin. Oncol. 15(12), 3481-3487 (1997).
    • (1997) J. Clin. Oncol. , vol.15 , Issue.12 , pp. 3481-3487
    • Pisters, P.W.1    Patel, S.R.2    Varma, D.G.3
  • 97
    • 0037096747 scopus 로고    scopus 로고
    • Gemcitabine and docetaxel in patients with unresectable leiomyosarcoma: Results of a Phase II trial
    • Hensley ML, Maki R, Venkatraman E et al.: Gemcitabine and docetaxel in patients with unresectable leiomyosarcoma: results of a Phase II trial. J. Clin. Oncol. 20(12), 2824-2831 (2002).
    • (2002) J. Clin. Oncol. , vol.20 , Issue.12 , pp. 2824-2831
    • Hensley, M.L.1    Maki, R.2    Venkatraman, E.3
  • 98
    • 0142181101 scopus 로고    scopus 로고
    • A Phase II trial of temozolomide in patients with unresectable or metastatic soft tissue sarcoma
    • Talbot SM, Keohan ML, Hesdorffer M et al.: A Phase II trial of temozolomide in patients with unresectable or metastatic soft tissue sarcoma. Cancer 98(9), 1942-1946 (2003).
    • (2003) Cancer , vol.98 , Issue.9 , pp. 1942-1946
    • Talbot, S.M.1    Keohan, M.L.2    Hesdorffer, M.3
  • 99
    • 0033571557 scopus 로고    scopus 로고
    • Paclitaxel in the treatment of patients with angiosarcoma of the scalp or face
    • Fata F, O'Reilly E, Ilson D et al.: Paclitaxel in the treatment of patients with angiosarcoma of the scalp or face. Cancer 86(10), 2034-2037 (1999).
    • (1999) Cancer , vol.86 , Issue.10 , pp. 2034-2037
    • Fata, F.1    O'Reilly, E.2    Ilson, D.3
  • 100
    • 0032764436 scopus 로고    scopus 로고
    • Phase II study of oral trofosfamide as palliative therapy in pretreated patients with metastatic soft-tissue sarcoma
    • Kollmannsberger C, Brugger W, Hartmann JT et al.: Phase II study of oral trofosfamide as palliative therapy in pretreated patients with metastatic soft-tissue sarcoma. Anticancer Drugs 10(5), 453-456 (1999).
    • (1999) Anticancer Drugs , vol.10 , Issue.5 , pp. 453-456
    • Kollmannsberger, C.1    Brugger, W.2    Hartmann, J.T.3
  • 101
    • 0027381042 scopus 로고
    • Primary chemotherapy and delayed surgery for nonmetastatic osteosarcoma of the extremities. Results in 164 patients preoperatively treated with high doses of methotrexate followed by cisplatin and doxorubicin
    • Bacci G, Picci P, Ferrari S et al.: Primary chemotherapy and delayed surgery for nonmetastatic osteosarcoma of the extremities. Results in 164 patients preoperatively treated with high doses of methotrexate followed by cisplatin and doxorubicin. Cancer 72(11), 3227-3238 (1993).
    • (1993) Cancer , vol.72 , Issue.11 , pp. 3227-3238
    • Bacci, G.1    Picci, P.2    Ferrari, S.3
  • 102
    • 0024215898 scopus 로고
    • Adjuvant chemotherapy for patients with high-grade soft-tissue sarcomas of the extremity
    • Chang AE, Kinsella T, Glatstein E et al.: Adjuvant chemotherapy for patients with high-grade soft-tissue sarcomas of the extremity. J. Clin. Oncol. 6(9), 1491-1500 (1988).
    • (1988) J. Clin. Oncol. , vol.6 , Issue.9 , pp. 1491-1500
    • Chang, A.E.1    Kinsella, T.2    Glatstein, E.3
  • 103
    • 0028334634 scopus 로고
    • Adjuvant CYVADIC chemotherapy for adult soft tissue sarcoma - Reduced local recurrence but no improvement in survival: A study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
    • Bramwell V, Rouesse J, Steward W et al.: Adjuvant CYVADIC chemotherapy for adult soft tissue sarcoma - reduced local recurrence but no improvement in survival: a study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group. J. Clin. Oncol. 12(6), 1137-1149 (1994).
    • (1994) J. Clin. Oncol. , vol.12 , Issue.6 , pp. 1137-1149
    • Bramwell, V.1    Rouesse, J.2    Steward, W.3
  • 104
    • 0019285848 scopus 로고
    • Adjuvant chemotherapy in nonmetastatic osteosarcoma: A Southwest Oncology Group Study
    • Herson J, Sutow WW, Elder K et al.: Adjuvant chemotherapy in nonmetastatic osteosarcoma: a Southwest Oncology Group Study. Med. Pediatr. Oncol. 8(4), 343-352 (1980).
    • (1980) Med. Pediatr. Oncol. , vol.8 , Issue.4 , pp. 343-352
    • Herson, J.1    Sutow, W.W.2    Elder, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.