Role of glutathione S-transferases in protection against lipid peroxidation: Overexpression of hGSTA2-2 in K562 cells protects against hydrogen peroxide-induced apoptosis and inhibits JNK and caspase 3 activation

Journal of Biological Chemistry

Volumn 276, Issue 22, 2001, Pages 19220-19230

  Yang, Yusong ^a   Cheng, Ji Zhong ^a   Singhal, Sharad S ^b   Saini, Manjit ^a   Pandya, Utpal ^a   Awasthi, Sanjay ^b   Awasthi, Yogesh C ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS AT ARLINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; PHOSPHOLIPIDS;

ISOENZYMES;

ENZYMES;

CASPASE 3; GLUTATHIONE TRANSFERASE; HUMAN GLUTATHIONE TRANSFERASE ALPHA1 1; HUMAN GLUTATHIONE TRANSFERASE ALPHA2 2; HYDROGEN PEROXIDE; HYDROPEROXIDE; ISOENZYME; LIPID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLCHOLINE HYDROPEROXIDE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; CASP3 PROTEIN, HUMAN; CASPASE; COMPLEMENTARY DNA; DNA; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; OXYGEN; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME MECHANISM; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LIVER; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; REDUCTION; SIGNAL TRANSDUCTION; TESTIS; CELL MEMBRANE; CELL STRAIN K 562; CHEMISTRY; ENZYME SPECIFICITY; ERYTHROCYTE; GENETIC TRANSFECTION; KINETICS; LIPID METABOLISM; METABOLISM; NICK END LABELING; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; SERODIAGNOSIS; TIME; TISSUE DISTRIBUTION; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL MEMBRANE; DNA; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; ERYTHROCYTES; GLUTATHIONE TRANSFERASE; HUMANS; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; JNK MITOGEN-ACTIVATED PROTEIN KINASES; K562 CELLS; KINETICS; LIPID METABOLISM; MAP KINASE KINASE 4; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; OXIDATIVE STRESS; OXYGEN; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN ISOFORMS; SUBSTRATE SPECIFICITY; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TIME FACTORS; TISSUE DISTRIBUTION; TRANSFECTION;

EID: 0035374455     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100551200     Document Type: Article

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