Using NMR for ligand discovery and optimization

Current Opinion in Chemical Biology

Volumn 8, Issue 4, 2004, Pages 387-391

  Villar, Hugo O ^a   Yan, Jiangli ^a   Hansen, Mark R ^a  

^a Triad Therapeutics Inc   (United States)

Author keywords

ADME; availability, distribution, metabolism and excretion; SAR; saturation transfer difference; STD; structure activity relationship; water ligand observed via gradient spectroscopy; WaterLOGSY

Indexed keywords

LIGAND;

ANALYTIC METHOD; DRUG DESIGN; DRUG RESEARCH; HUMAN; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REVIEW;

DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR WEIGHT;

EID: 3342966009     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpa.2004.05.002     Document Type: Review

References (39)

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