SCOPUS 정보 검색 플랫폼

Journal of Computer-Aided Molecular Design

Volumn 15, Issue 10, 2001, Pages 911-933

A genetic algorithm for structure-based de novo design

(3) Pegg, Scott C H a Haresco, Jose J a Kuntz, Irwin D a

a UNIVERSITY OF CALIFORNIA (United States)

Author keywords

ADAPT; Combinational chemistry; De novo design; DOCK; Genetic algorithm

Indexed keywords

ITERATIVE METHODS; LIGANDS;

ADAPT; COMBINATIONAL CHEMISTRY; DE NOVO DESIGN; DESIGN PROGRAMS; DOCKING CALCULATIONS; DRUG DESIGN; FITNESS FUNCTIONS; PROPERTY; SEARCH SPACES; STRUCTURE-BASED;

GENETIC ALGORITHMS;

1 PHENYL 3 (2 THIAZOLYL)THIOUREA; BENZOTHIADIAZINE DERIVATIVE; CATHEPSIN D; DELAVIRDINE; DIHYDROFOLATE REDUCTASE; EFAVIRENZ; EMIVIRINE; IMIDAZOPYRIDINE DERIVATIVE; L 697 661; L 737 126; LIGAND; MEN 10979; METHOTREXATE; N [4 CHLORO 3 (3 METHYL 2 BUTENYLOXY)PHENYL] 2 METHYL 3 FURANCARBOTHIOAMIDE; NSC 287474; PYRIDONE DERIVATIVE; PYRROLE DERIVATIVE; PYRROLOBENZOXAZEPINOME; QUINAXOLINONE; RD 4 2024; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; SULFONE DERIVATIVE; TNK 651; TRIVIRAPINE; UK 129 485; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

ARTICLE; CALCULATION; CHEMICAL STRUCTURE; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG BINDING SITE; DRUG DESIGN; GENETIC ALGORITHM; HUMAN IMMUNODEFICIENCY VIRUS 1; INFORMATION PROCESSING; METHODOLOGY; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN TARGETING; SAMPLING; STRUCTURE ACTIVITY RELATION;

EID: 0035570105 PISSN: 0920654X EISSN: None Source Type: Journal
DOI: 10.1023/A:1014389729000 Document Type: Article

Times cited : (126)

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