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Volumn 106, Issue 4, 2005, Pages 1147-1153

Lentiviral shRNA silencing of murine bone marrow cell CCR2 leads to persistent knockdown of CCR2 function in vivo

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR2; MESSENGER RNA; SHORT HAIRPIN RNA;

EID: 23744505924     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-12-4839     Document Type: Article
Times cited : (38)

References (51)
  • 1
    • 0036826849 scopus 로고    scopus 로고
    • Experimental basis of hematopoietic stem cell transplantation for treatment of autoimmune diseases
    • Van Bekkum DW. Experimental basis of hematopoietic stem cell transplantation for treatment of autoimmune diseases. J Leukoc Biol. 2002;72:609-620.
    • (2002) J Leukoc Biol , vol.72 , pp. 609-620
    • Van Bekkum, D.W.1
  • 2
    • 0032892490 scopus 로고    scopus 로고
    • Macrophages, lipoprotein metabolism, and atherosclerosis: Insights from murine bone marrow transplantation studies
    • Linton MF, Fazio S. Macrophages, lipoprotein metabolism, and atherosclerosis: insights from murine bone marrow transplantation studies. Curr Opin Lipidol. 1999;10:97-105.
    • (1999) Curr Opin Lipidol , vol.10 , pp. 97-105
    • Linton, M.F.1    Fazio, S.2
  • 3
    • 0029081525 scopus 로고
    • Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation
    • Boisvert WA, Spangenberg J, Curtiss LK. Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation. J Clin Invest. 1995;96:1118-1124.
    • (1995) J Clin Invest , vol.96 , pp. 1118-1124
    • Boisvert, W.A.1    Spangenberg, J.2    Curtiss, L.K.3
  • 4
  • 5
    • 0029794555 scopus 로고    scopus 로고
    • Targeted disruption of the murine tissue factor gene results in embryonic lethality
    • Toomey JR, Kratzer KE, Lasky NM, Stanton JJ, Broze GJ. Targeted disruption of the murine tissue factor gene results in embryonic lethality. Blood. 1996;88:1583-1587.
    • (1996) Blood , vol.88 , pp. 1583-1587
    • Toomey, J.R.1    Kratzer, K.E.2    Lasky, N.M.3    Stanton, J.J.4    Broze, G.J.5
  • 6
    • 9544227474 scopus 로고    scopus 로고
    • Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
    • Carmeliet P, Ferreira V, Breier G, et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature. 1996;383:73-75.
    • (1996) Nature , vol.383 , pp. 73-75
    • Carmeliet, P.1    Ferreira, V.2    Breier, G.3
  • 7
    • 0028864561 scopus 로고
    • Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency
    • Kohn DB, Weinberg KI, Nolta JA, et al. Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. Nat Med. 1995;1:1017-1023.
    • (1995) Nat Med , vol.1 , pp. 1017-1023
    • Kohn, D.B.1    Weinberg, K.I.2    Nolta, J.A.3
  • 8
    • 0036293903 scopus 로고    scopus 로고
    • Efficient oncoretroviral transduction of extended long-term culture-initiating cells and NOD/SCID repopulating cells: Enhanced reconstitution with gene-marked cells through an ex vivo expansion approach
    • Bjorgvinsdottir H, Bryder D, Sitnicka E, et al. Efficient oncoretroviral transduction of extended long-term culture-initiating cells and NOD/SCID repopulating cells: enhanced reconstitution with gene-marked cells through an ex vivo expansion approach. Hum Gene Ther. 2002;13:1061-1073.
    • (2002) Hum Gene Ther , vol.13 , pp. 1061-1073
    • Bjorgvinsdottir, H.1    Bryder, D.2    Sitnicka, E.3
  • 9
    • 0032573177 scopus 로고    scopus 로고
    • Reduction in levels of the cyclin-dependent kinase inhibitor p27(kip-1) coupled with transforming growth factor beta neutralization induces cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells
    • Dao MA, Taylor N, Nolta JA. Reduction in levels of the cyclin-dependent kinase inhibitor p27(kip-1) coupled with transforming growth factor beta neutralization induces cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells. Proc Natl Acad Sci USA. 1998;95:13006-130011.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13006-130011
    • Dao, M.A.1    Taylor, N.2    Nolta, J.A.3
  • 10
    • 0032535694 scopus 로고    scopus 로고
    • Adhesion to fibronectin maintains regenerative capacity during ex vivo culture and transduction of human hematopoietic stem and progenitor cells
    • Dao MA, Hashino K, Kato I, Nolta JA. Adhesion to fibronectin maintains regenerative capacity during ex vivo culture and transduction of human hematopoietic stem and progenitor cells. Blood. 1998;92:4612-4621.
    • (1998) Blood , vol.92 , pp. 4612-4621
    • Dao, M.A.1    Hashino, K.2    Kato, I.3    Nolta, J.A.4
  • 11
    • 0034131481 scopus 로고    scopus 로고
    • Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells
    • Abonour R, Williams DA, Einhorn L, et al. Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells. Nat Med. 2000;6:652-658.
    • (2000) Nat Med , vol.6 , pp. 652-658
    • Abonour, R.1    Williams, D.A.2    Einhorn, L.3
  • 12
    • 0031710033 scopus 로고    scopus 로고
    • A third-generation lentivirus vector with a conditional packaging, system
    • Dull T, Zufferey R, Kelly M, et al. A third-generation lentivirus vector with a conditional packaging, system. J Virol. 1998;72:8463-8471.
    • (1998) J Virol , vol.72 , pp. 8463-8471
    • Dull, T.1    Zufferey, R.2    Kelly, M.3
  • 13
    • 0031743608 scopus 로고    scopus 로고
    • Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
    • Zufferey R, Dull T Mandel RJ, et al. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J Virol. 1998;72:9873-9889.
    • (1998) J Virol , vol.72 , pp. 9873-9889
    • Zufferey, R.1    Dull, T.2    Mandel, R.J.3
  • 14
    • 0033865631 scopus 로고    scopus 로고
    • Apical gene transfer into quiescent human and canine polarized intestinal epithelial cells by lentivirus vectors
    • Seppen J, Barry SC, Klinkspoor JH, et al. Apical gene transfer into quiescent human and canine polarized intestinal epithelial cells by lentivirus vectors. J Virol. 2000;74:7642-7645.
    • (2000) J Virol , vol.74 , pp. 7642-7645
    • Seppen, J.1    Barry, S.C.2    Klinkspoor, J.H.3
  • 15
    • 0036116344 scopus 로고    scopus 로고
    • Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytes
    • Seppen J, Rijnberg M, Cooreman MP, Oude Elferink RPJ. Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytes. J Hepatol. 2002;36:459-465.
    • (2002) J Hepatol , vol.36 , pp. 459-465
    • Seppen, J.1    Rijnberg, M.2    Cooreman, M.P.3    Oude Elferink, R.P.J.4
  • 16
    • 0344305491 scopus 로고    scopus 로고
    • Correction of a mouse model of sickle cell disease: Lentiviral/ antisickling β-globin gene transduction of unmobilized, purified hematopoietic stem cells
    • Levasseur DN, Ryan TM, Pawlik KM, Townes TM. Correction of a mouse model of sickle cell disease: lentiviral/antisickling β-globin gene transduction of unmobilized, purified hematopoietic stem cells. Blood. 2003;102:4312-4319.
    • (2003) Blood , vol.102 , pp. 4312-4319
    • Levasseur, D.N.1    Ryan, T.M.2    Pawlik, K.M.3    Townes, T.M.4
  • 17
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 1998;391:806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 18
    • 0033669621 scopus 로고    scopus 로고
    • Post-transcriptional gene silencing across kingdoms
    • Cogoni C, Macino G. Post-transcriptional gene silencing across kingdoms. Curr Opin Genet Dev. 2000;10:638-643.
    • (2000) Curr Opin Genet Dev , vol.10 , pp. 638-643
    • Cogoni, C.1    Macino, G.2
  • 20
    • 0035942783 scopus 로고    scopus 로고
    • RNA interference, the short answer
    • Bass BL. RNA interference, the short answer. Nature. 2001;411:428-429.
    • (2001) Nature , vol.411 , pp. 428-429
    • Bass, B.L.1
  • 21
    • 0035261255 scopus 로고    scopus 로고
    • Post-transcriptional gene silencing by double-stranded RNA
    • Hammond SM, Gaudy AA, Hannon GJ. Post-transcriptional gene silencing by double-stranded RNA. Nat Rev Genet. 2001;2:110-119.
    • (2001) Nat Rev Genet , vol.2 , pp. 110-119
    • Hammond, S.M.1    Gaudy, A.A.2    Hannon, G.J.3
  • 23
    • 0035281741 scopus 로고    scopus 로고
    • RNA interference
    • Sharp PA. RNA interference. Genes Dev. 2001;15:485-490.
    • (2001) Genes Dev , vol.15 , pp. 485-490
    • Sharp, P.A.1
  • 24
    • 0035859046 scopus 로고    scopus 로고
    • Gene silencing as an adaptive defence against viruses
    • Waterhouse PM, Wang MB, Lough T. Gene silencing as an adaptive defence against viruses. Nature. 2001;411:834-842.
    • (2001) Nature , vol.411 , pp. 834-842
    • Waterhouse, P.M.1    Wang, M.B.2    Lough, T.3
  • 25
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 2001;411:494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 26
    • 0036066508 scopus 로고    scopus 로고
    • SiRNA-directed inhibition of HIV-1 infection
    • Novina CD, Murray MF, Dykxhoorn DM, et al. SiRNA-directed inhibition of HIV-1 infection. Nat Med. 2002;8:681-686.
    • (2002) Nat Med , vol.8 , pp. 681-686
    • Novina, C.D.1    Murray, M.F.2    Dykxhoorn, D.M.3
  • 27
    • 0037173610 scopus 로고    scopus 로고
    • Modulation of HIV-1 replication by RNA interference
    • Jacque JM, Triques K, Stevenson M. Modulation of HIV-1 replication by RNA interference. Nature. 2002;418:435-438.
    • (2002) Nature , vol.418 , pp. 435-438
    • Jacque, J.M.1    Triques, K.2    Stevenson, M.3
  • 28
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science. 2002;296:550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 29
    • 0037452812 scopus 로고    scopus 로고
    • A general method for gene knockdown in mice using lentiviral vectors expressing small interfering RNA
    • Tiscornia G. Singer O, Ikawa M, Verma IM. A general method for gene knockdown in mice using lentiviral vectors expressing small interfering RNA. Proc Natl Acad Sci USA. 2003;100:1844-1848.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1844-1848
    • Tiscornia, G.1    Singer, O.2    Ikawa, M.3    Verma, I.M.4
  • 30
    • 0037422583 scopus 로고    scopus 로고
    • Inhibiting HIV-1 infection in human Tcells by lentiviral-mediated delivery of small interfering RNA against CCR5
    • Qin XF, An DS, Chen IS, Baltimore D. Inhibiting HIV-1 infection in human Tcells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc Natl Acad Sci USA. 2003;100:183-188.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 183-188
    • Qin, X.F.1    An, D.S.2    Chen, I.S.3    Baltimore, D.4
  • 31
    • 0042267194 scopus 로고    scopus 로고
    • Efficient lentiviral vectors for short hairpin RNA delivery into human cells
    • An DS, Xie Y, Mao SH, Morizono K, Kung SK, Chen IS. Efficient lentiviral vectors for short hairpin RNA delivery into human cells. Hum Gene Ther. 2003;14:1207-1212.
    • (2003) Hum Gene Ther , vol.14 , pp. 1207-1212
    • An, D.S.1    Xie, Y.2    Mao, S.H.3    Morizono, K.4    Kung, S.K.5    Chen, I.S.6
  • 32
    • 1642441675 scopus 로고    scopus 로고
    • Inhibition of GM-CSF receptor function by stable RNA interference in a NOD/SCID mouse hematopoietic stem cell transplantation model
    • Scherr M, Battmer K, Dallmann I, Ganser A, Eder M. Inhibition of GM-CSF receptor function by stable RNA interference in a NOD/SCID mouse hematopoietic stem cell transplantation model. Oligonucleotides. 2003;13:353-363.
    • (2003) Oligonucleotides , vol.13 , pp. 353-363
    • Scherr, M.1    Battmer, K.2    Dallmann, I.3    Ganser, A.4    Eder, M.5
  • 33
    • 0032572719 scopus 로고    scopus 로고
    • -/- mice reveals a role for chemokines in the initiation of atherosclerosis
    • -/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature. 1998;394:894-897.
    • (1998) Nature , vol.394 , pp. 894-897
    • Boring, L.1    Gosling, J.2    Cleary, M.3    Charo, I.F.4
  • 34
    • 0033060017 scopus 로고    scopus 로고
    • Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient mice
    • Dawson TC, Kuziel WA, Osahar TA, Maeda N. Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient mice. Atherosclerosis. 1999;143:205-211.
    • (1999) Atherosclerosis , vol.143 , pp. 205-211
    • Dawson, T.C.1    Kuziel, W.A.2    Osahar, T.A.3    Maeda, N.4
  • 35
    • 0037343268 scopus 로고    scopus 로고
    • Transplantation of monocyte CC-chemokine receptor 2-deficient bone marrow into ApoE3-Leiden mice inhibits atherogenesis
    • Quo J, Van Eck M, Twisk J, et al. Transplantation of monocyte CC-chemokine receptor 2-deficient bone marrow into ApoE3-Leiden mice inhibits atherogenesis. Arterioscl Thromb Vasc Biol. 2003;23:447-453.
    • (2003) Arterioscl Thromb Vasc Biol , vol.23 , pp. 447-453
    • Quo, J.1    Van Eck, M.2    Twisk, J.3
  • 36
    • 1642452660 scopus 로고    scopus 로고
    • Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells
    • Nishitsuji H, Ikeda T, Miyoshi H, Ohashi T, Kannagi M, Masuda T. Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells. Microbes Infect. 2004;6:76-85.
    • (2004) Microbes Infect , vol.6 , pp. 76-85
    • Nishitsuji, H.1    Ikeda, T.2    Miyoshi, H.3    Ohashi, T.4    Kannagi, M.5    Masuda, T.6
  • 37
    • 0042163205 scopus 로고    scopus 로고
    • Aorta of ApoE-deficient mice responds to atherogenic stimuli by a prelesional increase and subsequent decrease in the expression of antioxidant enzymes
    • 't Hoen PA, Van der Lans CA, Van Eck M, Bijsterbosch MK, Van Berkel TJ, Twisk J. Aorta of ApoE-deficient mice responds to atherogenic stimuli by a prelesional increase and subsequent decrease in the expression of antioxidant enzymes. Circ Res. 2003;93:262-269.
    • (2003) Circ Res , vol.93 , pp. 262-269
    • Hoen, P.A.1    Van Der Lans, C.A.2    Van Eck, M.3    Bijsterbosch, M.K.4    Van Berkel, T.J.5    Twisk, J.6
  • 38
    • 0030819379 scopus 로고    scopus 로고
    • Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
    • Zufferey R, Nagy D, Mandel RJ, Naldini L, Trono D. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat Biotechnol. 1997;15:871-875.
    • (1997) Nat Biotechnol , vol.15 , pp. 871-875
    • Zufferey, R.1    Nagy, D.2    Mandel, R.J.3    Naldini, L.4    Trono, D.5
  • 39
    • 0036713630 scopus 로고    scopus 로고
    • Titering lentiviral vectors: Comparison of DNA, RNA and marker expression methods
    • Sastry L, Johnson T, Hobson MJ, Smucker B, Cornetta K. Titering lentiviral vectors: comparison of DNA, RNA and marker expression methods. Gene Ther. 2002;9:1155-1162.
    • (2002) Gene Ther , vol.9 , pp. 1155-1162
    • Sastry, L.1    Johnson, T.2    Hobson, M.J.3    Smucker, B.4    Cornetta, K.5
  • 40
    • 0027475379 scopus 로고
    • Long-term generation and expansion of human primitive hematopoietic progenitor cells in vitro
    • Srour EF, Brandt JE, Briddell RA, Grigsby S, Leemhuis T, Hoffman R. Long-term generation and expansion of human primitive hematopoietic progenitor cells in vitro. Blood. 1993;81:661-669.
    • (1993) Blood , vol.81 , pp. 661-669
    • Srour, E.F.1    Brandt, J.E.2    Briddell, R.A.3    Grigsby, S.4    Leemhuis, T.5    Hoffman, R.6
  • 41
    • 0034669932 scopus 로고    scopus 로고
    • High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors
    • Salmon P, Kindler V, Ducrey O, Chapuis B, Zubler RH, Trono D. High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors. Blood. 2000;96:3392-3398.
    • (2000) Blood , vol.96 , pp. 3392-3398
    • Salmon, P.1    Kindler, V.2    Ducrey, O.3    Chapuis, B.4    Zubler, R.H.5    Trono, D.6
  • 45
    • 0037441587 scopus 로고    scopus 로고
    • Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: Risk of insertional mutagenesis
    • Woods N-B, Muessig A, Schmidt M, et al. Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis. Blood. 2003;101:1284-1289.
    • (2003) Blood , vol.101 , pp. 1284-1289
    • Woods, N.-B.1    Muessig, A.2    Schmidt, M.3
  • 46
    • 0030699387 scopus 로고    scopus 로고
    • Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor
    • Kurihara T, Warr G, Loy J, Bravo R. Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor. J Exp Med. 1997;186:1757-1762.
    • (1997) J Exp Med , vol.186 , pp. 1757-1762
    • Kurihara, T.1    Warr, G.2    Loy, J.3    Bravo, R.4
  • 47
    • 12144286102 scopus 로고    scopus 로고
    • Gene therapy via blockade of monocyte chemoattractant protein-1 for renal fibrosis
    • Wada T, Furuichi K, Sakai N, et al. Gene therapy via blockade of monocyte chemoattractant protein-1 for renal fibrosis. J Am Soc Nephrol. 2004;15:940-948.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 940-948
    • Wada, T.1    Furuichi, K.2    Sakai, N.3
  • 48
    • 0037443571 scopus 로고    scopus 로고
    • Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: Role of the CCL2-CCR2 axis
    • Maus U, Waelsch K, Kuziel WA, et al. Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: role of the CCL2-CCR2 axis. J Immunol. 2003;170:3273-3278.
    • (2003) J Immunol , vol.170 , pp. 3273-3278
    • Maus, U.1    Waelsch, K.2    Kuziel, W.A.3
  • 49
    • 0038419800 scopus 로고    scopus 로고
    • Induction of an interferon response by RNAi vectors in mammalian cells
    • Bridge AJ, Pebernard S, Ducraux A, Nicoulaz, A-L, Iggo R. Induction of an interferon response by RNAi vectors in mammalian cells. Nat Gen. 2003;34:263-264.
    • (2003) Nat Gen , vol.34 , pp. 263-264
    • Bridge, A.J.1    Pebernard, S.2    Ducraux, A.3    Nicoulaz, A.-L.4    Iggo, R.5
  • 51
    • 0033021138 scopus 로고    scopus 로고
    • Position-dependent inhibition of class-switch recombination by PGK-neo cassettes inserted into the immunoglobulin heavy chain constant region locus
    • Seidl KJ, Manis JP, Bottaro A, et al. Position-dependent inhibition of class-switch recombination by PGK-neo cassettes inserted into the immunoglobulin heavy chain constant region locus. Proc Natl Acad Sci USA. 1999;96:3000-3005.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3000-3005
    • Seidl, K.J.1    Manis, J.P.2    Bottaro, A.3


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