Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: Risk of insertional mutagenesis

Blood

Volumn 101, Issue 4, 2003, Pages 1284-1289

  Woods, Niels Bjarne ^b   Muessig, Arne ^b   Schmidt, Manfred ^b   Flygare, Johan ^b   Olsson, Karin ^b   Salmon, Patrick ^b   Trono, Didier ^b   Von Kalle, Christof ^a   Karlsson, Stefan ^b  

^a CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ELONGATION FACTOR 1; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLONY FORMING UNIT GM; CONTROLLED STUDY; DNA SEQUENCE; FLUORESCENCE ACTIVATED CELL SORTER; GENE EXPRESSION; GENE INSERTION; GENETIC TRANSDUCTION; HEMATOLOGIC DISEASE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; ONCOGENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCID MOUSE; TRANSGENE; TUMOR SUPPRESSOR GENE; UMBILICAL CORD BLOOD;

EID: 0037441587     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-07-2238     Document Type: Article

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