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Volumn 21, Issue 25, 2002, Pages 4009-4019

Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

(7) Von Haefen, Clarissa a Wieder, Thomas a Gillissen, Bernd a Stärck, Lilian a Graupner, Vilma a Dörken, Bernd a Daniel, Peter T a

a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN (Germany)

Author keywords

Bax; Ceramide; DU 145 cells; HCT116 cells; Mitochondria; Proapoptotic genes

Indexed keywords

BENZYLOCARBONYLASPARTYLGLUTAMYLVALYLASPARTYLFLUOROMETHYLKETONE; BENZYLOCARBONYLVALYLALANYLASPARTYLFLUOROMETHYLKETONE; CASPASE 3; CASPASE 3 INHIBITOR; CERAMIDE; CYTOCHROME C; DNA FRAGMENT; GENE PRODUCT; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL ACTIVATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME RELEASE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; KNOCKOUT GENE; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN FAMILY; SIGNAL TRANSDUCTION; STRESS; WILD TYPE;

AMINO ACID CHLOROMETHYL KETONES; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL FRACTIONATION; CERAMIDES; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROME C GROUP; EPIRUBICIN; FLOW CYTOMETRY; HUMANS; MALE; MITOCHONDRIA; OLIGOPEPTIDES; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RETROVIRIDAE; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0037030465 PISSN: 09509232 EISSN: None Source Type: Journal
DOI: 10.1038/sj.onc.1205497 Document Type: Article

Times cited : (172)

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