In vitro approaches to evaluate ADMET drug properties

Current Topics in Medicinal Chemistry

Volumn 4, Issue 7, 2004, Pages 701-706

  Li, Albert P ^a  

^a Advanced Pharmaceutical Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); ANTIHISTAMINIC AGENT; ANTIHYPERTENSIVE AGENT; ASTEMIZOLE; COMPLEMENTARY DNA; COUMARIN; CYCLOSPORIN; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2B1; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; DEXTROMETHORPHAN; DRUG METABOLIZING ENZYME; ERYTHROMYCIN; FURAFYLLINE; GLYCOPROTEIN P; ITRACONAZOLE; KETOCONAZOLE; MEPHENYTOIN; MIBEFRADIL; PHENACETIN; PHENYTOIN; RIFAMPICIN; SULFAPHENAZOLE; TERFENADINE; UNINDEXED DRUG; DRUG;

CARDIOTOXICITY; CELL MEMBRANE; CELL STRAIN CACO 2; CONCENTRATION (PARAMETERS); CROSS REACTION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DEVELOPMENT; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MARKETING; DRUG METABOLISM; DRUG TOXICITY; DRUG TRANSPORT; DRUG UPTAKE; DRUG WITHDRAWAL; FIRST PASS EFFECT; HEART ARRHYTHMIA; HUMAN; IN VITRO STUDY; INTESTINE ABSORPTION; LIVER CELL; LIVER MICROSOME; LIVER TOXICITY; NONHUMAN; PROBABILITY; REVIEW; ARTICLE; BIOAVAILABILITY; CELL CULTURE; CYTOLOGY; DRUG DESIGN; DRUG EFFECT; DRUG INTERACTION; DRUG SCREENING; DRUG STABILITY; LIVER; METABOLISM; METHODOLOGY;

BIOLOGICAL AVAILABILITY; CELLS, CULTURED; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; DRUG INTERACTIONS; DRUG STABILITY; DRUG TOXICITY; HUMANS; LIVER; PHARMACEUTICAL PREPARATIONS;

EID: 2342512256     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568026043451050     Document Type: Review

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