Mutational analysis of the human 2B4 (CD244)/CD48 interaction: Lys 68 and Glu70 in the V domain of 2B4 are critical for CD48 binding and functional activation of NK cells

Journal of Immunology

Volumn 175, Issue 2, 2005, Pages 1005-1013

  Mathew, Stephen O ^a   Kumaresan, Pappanaicken R ^a,b   Lee, Jae Kyung ^a   Huynh, Van T ^a   Mathew, Porunelloor A ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ANTIGEN 2B4; CD2 ANTIGEN; CD244 ANTIGEN; CD48 ANTIGEN; FC RECEPTOR; GLUTAMIC ACID; HYBRID PROTEIN; LIGAND; LYSINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIGEN BINDING; ARTICLE; CALCIUM TRANSPORT; CELL ACTIVATION; CELL STRAIN COS7; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LIGAND BINDING; MELANOMA CELL; MOUSE; MUTATIONAL ANALYSIS; NATURAL KILLER CELL; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS;

EID: 23244449293     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.2.1005     Document Type: Article

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