Expression cloning and function of the rat NK activating and inhibitory receptors NKR-P1A and -P1B

International Immunology

Volumn 15, Issue 3, 2003, Pages 411-416

  Li, Jennifer ^a   Rabinovich, Brian A ^a   Hurren, Rose ^a   Shannon, John ^a   Miller, Richard G ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Calcium flux; Cytotoxicity; Lymphokine activated killer cell

Indexed keywords

CELL RECEPTOR; CHROMIUM 51; COMPLEMENTARY DNA; MONOCLONAL ANTIBODY; NATURAL KILLER CELL RECEPTOR; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASSAY; CALCIUM TRANSPORT; CELL CLONING; CELL FUNCTION; CELL LINE; CONTROLLED STUDY; DNA LIBRARY; FLUORESCENCE ACTIVATED CELL SORTING; GENE IDENTIFICATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RETROVIRUS;

ANIMALS; ANTIGENS, SURFACE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; KILLER CELLS, NATURAL; LECTINS, C-TYPE; MICE; RATS; RECEPTORS, IMMUNOLOGIC;

EID: 0037343043     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxg046     Document Type: Article

References (41)

1. Su, R. C., Kung, S. K., Gariepy, J., Barber, B. H. and Miller, R. G. 1998. NK cells can recognize different forms of class I MHC. J. Immunol. 161:755.
2. Lanier, L. L. 1998. NK cell receptors. Annu. Rev. Immunol. 16:359.
3. Kärre, K. 1991. MHC gene control of the natural killer system at the level of the target and the host. Semin. Cancer Biol. 2:295.
4. Kärre, K., Ljunggren, H. G., Piontek, G. and Kiessling, R. 1986. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. Nature 319:675.
5. Chambers, W. H., Vujanovic, N. L., DeLeo, A. B., Olszowy, M. W., Herberman, R. B. and Hiserodt, J. C. 1989. Monoclonal antibody to a triggering structure expressed on rat natural killer cells and adherent lymphokine-activated killer cells. J. Exp. Med. 169:1373.
6. Ryan, J. C., Niemi, E. C., Goldfien, R. D., Hiserodt, J. C. and Seaman, W. E. 1991. NKR-P1, an activating molecule on rat natural killer cells, stimulates phosphoinositide turnover and a rise in intracellular calcium. J. Immunol. 147:3244.
7. Chambers, W. H., Vujanovic, N. L., DeLeo, A. B., Olszowy, M. W., Herberman, R. B. and Hiserodt, J. C. 1989. Monoclonal antibody to a triggering structure expressed on rat natural killer cells and adherent lymphokine-activated killer cells. J. Exp. Med. 169:1373.
8. Giorda, R., Rudert, W. A., Vavassori, C., Chambers, W. H., Hiserodt, J. C. and Trucco, M. 1990. NKR-P1, a signal transduction molecule on natural killer cells. Science 249:1298.
9. Ryan, J. C., Niemi, E. C., Nakamura, M. C. and Seaman, W. E. 1995. NKR-P1A is a target-specific receptor that activates natural killer cell cytotoxicity. J. Exp. Med, 181:1911.
10. Burshtyn, D. N., Yang, W., Yi, T. and Long, E. O. 1997. A novel phosphotyrosine motif with a critical amino acid at position -2 for the SH2 domain-mediated activation of the tyrosine phosphatase SHP. J. Biol. Chem. 272:13066.
11. Long, E. O. and Wagtmann, N. 1997. Natural killer cell receptors. Curr. Opin. Immunol. 9:344.
12. Wu, J., Song, Y., Bakker, A. B., Bauer, S., Spies, T., Lanier, L. L. and Phillips, J. H. 1999. An activating immunoreceptor complex formed by NKG2D and DAP10. Science 285:730.
13. Moretta, A., Bottino, C., Vitale, M., Pende, D., Cantoni, C., Mingari, M. C., Biassoni, R. and Moretta, L. 2001. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu. Rev. Immunol. 19:197.
14. Lanier, L. L. 2001. On guard - activating NK cell receptors. Nat. Immunol. 2:23.
15. Giorda, R. and Trucco, M. 1991. Mouse NKR-P1. A family of genes selectively coexpressed in adherent lymphokine-activated killer cells. J. Immunol. 147:1701.
16. Plougastel, B., Matsumoto, K., Dubbelde, C. and Yokoyama, W. M. 2001. Analysis of a 1-Mb BAC contig overlapping the mouse Nkrp1 cluster of genes: cloning of three new Nkrp1 members, Nkrp1d, Nkrp1e, and Nkrp1f. Immunogenetics 53:592.
17. Kung, S. K., Su, R. C., Shannon, J. and Miller, R. G. 1999. The NKR-P1B gene product is an inhibitory receptor on SJL/J NK cells. J. Immunol. 162:5876.
18. Carlyle, J. R., Martin, A., Mehra, A., Attisano, L., Tsui, F. W. and Zuniga-Pflucker, J. C. 1999. Mouse NKR-P1B, a novel NK1.1 antigen with inhibitory function. J. Immunol. 162:5917.
19. + T cells. J. Exp. Med. 186:1957.
20. Karlhofer, F. M. and Yokoyama, W. M. 1991. Stimulation of murine natural killer (NK) cells by a monoclonal antibody specific for the NK1.1 antigen. IL-2-activated NK cells possess additional specific stimulation pathways. J. Immunol. 146:3662.
21. + T cells and natural killer cells share expression of NKR-P1A and NKR-P1D. Nat. Immun. 15:259.
22. Reynolds, C. W., Bere, E. W., Jr and Ward, J. M. 1984. Natural killer activity in the rat. III. Characterization of transplantable large granular lymphocyte (LGL) leukemias in the F344 rat. J. Immunol. 132:534.
23. Arase, H., Saito, T., Phillips, J. H. and Lanier, L. L. 2001. Cutting edge: the mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha(2) integrin, very late antigen-2). J. Immunol. 167:1141.
24. Onishi, M., Kinoshita, S., Morikawa, Y., Shibuya, A., Phillips, J., Lanier, L. L., Gorman, D. M., Nolan, G. P., Miyajima, A. and Kitamura, T. 1996. Applications of retrovirus-mediated expression cloning. Exp. Hematol. 24:324.
25. Morita, S., Kojima, T. and Kitamura, T. 2000. Plat-E: an efficient and stable system for transient packaging of retroviruses. Gene Ther. 7:1063.
26. Cohen, G. B., Gandhi, R. T., Davis, D. M., Mandelboim, O., Chen, B. K., Strominger, J. L. and Baltimore, D. 1999. The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells. Immunity 10:661.
27. Rabinovich, B. A., Shannon, J., Su, R. C. and Miller, R. G. 2000. Stress renders T cell blasts sensitive to killing by activated syngeneic NK cells. J. Immunol. 165:2390.
28. 2+-measurements with visible wavelength indicators in isolated cardiac myocytes. Cell Calcium 14:359.
29. Novak, E. J. and Rabinovitch, P. S. 1994. Improved sensitivity in flow cytometric intracellular ionized calcium measurement using fluo-3/Fura Red fluorescence ratios. Cytometry 17:135.
30. Burshtyn, D. and Long, E. 1997. Regulation through inhibitory receptors: lessons from natural killer cells. Trends Cell Biol. 7:473.
31. Blery, M., Kubagawa, H., Chen, C.-C., Vely, F., Cooper, M. D. and Vivier, E. 1998. The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP. Proc. Natl Acad. Sci. USA 95:2446.
32. Vely, F. and Vivier, E. 1997. Commentary: conservation of structural features reveals the existence of a large family of inhibitory cell surface receptors and noninhibitory/activatory counterparts. J. Immunol. 159:2075.
33. Ravetch, J. V. and Lanier, L. L. 2000. Immune inhibitory receptors. Science 290:84.
34. Rajagopalan, S., Fu, J. and Long, E. O. 2001. Cutting edge: induction of IFN-gamma production but not cytotoxicity by the Killer Cell Ig-Like Receptor KIR2DL4 (CD158d) in resting NK cells. J. Immunol. 167:1877.
35. Faure, M. and Long, E. O. 2002. KIR2DL4 (CD158d), an NK cell-activating receptor with inhibitory potential. J. Immunol. 168:6208.
36. Yusa, S.-I., Catina, T. L. and Campbell, K. S. 2002. SHP-1- and phosphotyrosine-independent inhibitory signaling by a killer cell Ig-like receptor cytoplasmic domain in human NK cells. J. Immunol. 168:5047.
37. Kaminsky, S. G., Nakamura, I. and Cudkowicz, G. 1983. Selective defect of natural killer and killer cell activity against lymphomas in SJL mice: low responsiveness to interferon inducers. J. Immunol. 130:1980.
38. Lin, T. Z. and Ponzio, N. M. 1991. Syngeneic B lymphoma cells provide a unique stimulus to natural killer (NK) cells in genetically low-NK SJL/J mice. J. Leukoc. Biol. 49:48.
39. Reynolds, C. W., Bere, E. W., Jr and Ward, J. M. 1984. Natural killer activity in the rat. III. Characterization of transplantable large granular lymphocyte (LGL) leukemias in the F344 rat. J. Immunol. 132:534.
40. Miller, J. S. 2002. Biology of natural killer cells in cancer and infection. Cancer Invest. 20:405.
41. Shi, F., Ljunggren, H. G. and Sarvetnick, N. 2001. Innate immunity and autoimmunity: from self-protection to self-destruction. Trends Immunol. 22:97.