Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 17, 2005, Pages 5104-5112

  Andersen, Trine F ^a   Vogensen, Stine B ^a   Jensen, Lars S ^a   Knapp, Kolja M ^a   Strømgaard, Kristian ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

AMPA receptors; Glutamate receptors; Natural products; Polyamine toxins

Indexed keywords

AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; PHILANTHOTOXIN; PHILANTHOTOXIN 56; POLYAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM TRANSPORT; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; ISOTOPE LABELING; MEMBRANE PERMEABILITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RECEPTOR BINDING;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DESIGN; ISOTOPES; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR STRUCTURE; POLYAMINES; RECEPTORS, AMPA; SPECTROPHOTOMETRY, ULTRAVIOLET; TYROSINE;

EID: 22844445352     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.05.023     Document Type: Article

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