Five years of research on health risks and benefits of Maillard reaction products: An update

Molecular Nutrition and Food Research

Volumn 49, Issue 7, 2005, Pages 663-672

  Somoza, Veronika ^a  

^a DEUTSCHE FORSCHUNGSANSTALT FÜR LEBENSMITTELCHEMIE   (Germany)

Author keywords

Antioxidative effects; Cancer; Chemoprevention; Glycation; Melanoidins; Metabolic transit; Microbial degradation; Review

Indexed keywords

ANTIOXIDANT; ENZYME; MELANOIDIN POLYMERS; MUTAGENIC AGENT; POLYMER; XENOBIOTIC AGENT;

CHEMISTRY; CHEMOPROPHYLAXIS; CONFERENCE PAPER; DIET; GLYCATION; GLYCOSYLATION; HEALTH PROMOTION; HUMAN; INTESTINE; METABOLISM; RISK FACTOR; TRANSPORT AT THE CELLULAR LEVEL;

ANTIOXIDANTS; BIOLOGICAL TRANSPORT; CHEMOPREVENTION; DIET; ENZYMES; GLYCOSYLATION; HEALTH PROMOTION; HUMANS; INTESTINES; MAILLARD REACTION; MUTAGENS; POLYMERS; RISK FACTORS; XENOBIOTICS;

ANIMALIA;

EID: 22444451523     PISSN: 16134125     EISSN: None     Source Type: Journal    
DOI: 10.1002/mnfr.200500034     Document Type: Conference Paper

References (65)

1. Skog, K., Johansson, M., Jägerstad, M., Carcinogenic heterocyclic amines in model systems and cooked foods: a review on formation, occurrence and intake. J. Food Chem. Toxicol. 1998, 36, 879-896.
2. Granvogl, M., Jezussek, M., Koehler, P., Schieberle, P., Quantitation of 3-aminopropionamide in potatoes - a minor but potent precursor in acrylamide formation. J. Agric. Food Chem. 2004, 52, 4751-4757.
3. Pintauro, S. J., Lee, T.-C., Chichester, C. O., Physiological, toxicological and nutritional aspects of various Maillard browned products. In: Waller, R., Feather, M. S. (Eds.), The Maillard Reaction in foods and nutrition. American Chemical Society, New York 1983, pp. 379-407.
4. Kitts, D. D., Wu, C. H., Powrie, W. D., Effect of glucose-lysine Maillard reaction product fractions on tissue xenobiotic enzyme systems. J. Agric. Food Chem. 1993, 41, 2359-2363.
5. Wenzel, E., Tasto, S., Erbersdobler, H. F., Faist, V., Effect of heat-treated proteins on selected parameters of the biotransformation system in the rat. Ann. Nutr. Metab. 2002, 46, 9-16.
6. Baynes, J. W., Monnier, V. M., The Maillard Reaction in Aging, Diabetes and Nutrition. A. R. Liss, New York 1989.
7. Vlassara, H., et al., Macrophage receptor-mediated processing and regulation of advanced glycosylation endproduct (AGE)-modified proteins: role in diabetes and aging. In: Baynes, J. W., Monnier, V. M. (Eds.), The Maillard Reaction in Aging, Diabetes and Nutrition, A. R. Liss, New York 1989.
8. Thornalley, P. J., Glutathione-dependent detoxification of alpha-oxoaldehydes by the glyoxalase system: involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors. Chem. Biol. Interact. 1998, 111-112, 137-151.
9. Ames, J. M., Wynne, A., Hofmann, A., Plos, S., Gibson, G. R., The effect of a model melanoidin mixture on faecal bacterial populations in vitro. Br. J. Nutr. 1999, 82, 489-495.
10. Dell'Aquila, C., Microbial degradation of heated gluten-glucose systems. Implications for gut health. In: Vegarud, G., Morales, F. (Eds.), Melanoidins in Food and Health, EC Directorate for Research 2003, Vol. 4, EUR 20722, pp.181-183.
11. Faist, V., Krome, K., Ames, J., Erbersdobler, H. F., Effects of Non-Enzymatic Browning Products formed by Roasting of Glucose/Glycine- and Glucose/Casein-Mixtures on NADPH-Cytochrome c-Reductase and Glutathione-S- transferase in Caco-2 Cells. In: Ames, J. M. (Ed.), Melanoidins in Food and Health, EC Directorate for Research 2001, Vol. 2, EUR 19881, pp. 95-106.
12. Powrie, W. D., Wu, C. H., Molund, V. P., Browning reaction systems as sources of mutagens and antimutagens. Environ. Health Perspect. 1986, 67, 47-54.
13. Solyakov, A., Skog, K., Jägerstad, M., Binding of mutagenic/ carcinogenic heterocyclic amines to MRPs under stimulated gastrointestinal conditions. In: Fogliano, V., Henle, T. (Eds.), Melanoidins in Food and Health, EC Directorate for Research (2002) Vol. 3, pp. 195-197.
14. Daglia, M., Tarsi, R., Papetti, A., Grisoli, P., et al., Antiadhesive effect of green and roasted coffee on Streptococcus mutans' adhesive properties on saliva-coated hydroxyapatite beads. J. Agric. Food Chem. 2002, 50, 1225-1229.
15. Faist, V., Erbersdobler, H. F., Metabolic transit and in vivo effects of melanoidins and precursor compounds deriving from the Maillard reaction. Ann. Nutr. Metab. 2001, 45, 1-12.
16. Homma, S., Fujimaki, M., Growth response of rats fed a diet containing nondialyzable melanoidin. Prog. Fd. Nutr. Sci. 1981, 5, 209-216.
17. Valle-Riestra, J., Barnes, R., Digestion of heat-damaged egg albumen by the rat. J. Nutr. 1969, 100, 873-882.
18. Finot, P. A., Magnenat, E., Metabolic transit of early and advanced Maillard products. Prog. Fd. Nutr. Sci. 1981, 5, 193-207.
19. Erbersdobler, H. F., Faist, V., Metabolic transit of Amadori products. Nahrung/Food 2001, 45, 177-181.
20. ε-Carboxymethyllysine. Czech. Journal of Food Science 2000, 18, 116.
21. Henle, T., Schwenger, V., Ritz, E., Preliminary Studies on the Renal Handling of Lactuloselysine from Milk Products. Czech. Journal of Food Sciences 2000, 18, 101-102.
22. Foerster, A., Henle, T., Glycation in food and metabolic transit of dietary AGEs (advanced glycation end-products): studies on the urinary excretion of pyrraline. Biochem. Soc. Trans. 2003, 31(Pt 6), 1383-1385.
23. Bergmann, R., Helling, R., Heichert, C., Scheunemann, M., et al., Radio fluorination and positron emission tomography (PET) as a new approach to study the in vivo distribution and elimination of the advanced glycation endproducts N epsilon-carboxymethyllysine (CML) and N-epsilon-carboxyethyllysine (CEL). Nahrung/Food 2001, 45, 182-188.
24. Wilkinson, J., Clapper, M. L., Detoxication enzymes and chemoprevention. Proc. Soc. Exp. Biol. Med. 1997, 216, 192-200.
25. Prochaska, H. J., Talalay, P., Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver. Cancer Res. 1988, 48, 4776-4782.
26. Hofmann, T., Ames, J., Krome, K., Faist, V., Determination of the molecular weight distribution of non-enzymatic browning products formed by roasting of glucose and glycine and studies on their effects on NADPH-cytochrome c-reductase and glutathione-S-transferase in Caco-2 cells. Nahrung/Food 2001, 45, 189-194.
27. Faist, V., Lindenmeier, M., Geisler, C., Erbersdobler, H. F., Hofmann, T., Influence of molecular weight fractions isolated from roasted malt on the enzyme activities of NADPH-cytochrome c-reductase and glutathione-S-transferase in Caco-2 cells. J. Agric. Food Chem. 2002, 50, 602-606.
28. Lindenmeier, M., Faist, V., Hofmann, T., Structural and functional characterization of pronyl-lysine, a novel protein modification in bread crust melanoidins showing in vitro antioxidative and phase I/II enzyme modulating activity. J. Agric. Food Chem. 2002, 50, 6997-7006.
29. Faist, V., Hofmann, T., Zill, H., Baynes, J. W., et al., Effects of dietary N-epsilon-Carboxymethyllysine on expression of the biotransformation enzyme, Glutathione S-transferase, in the rat. In: Horiuchi, S., Taniguchi, N., Hayase, F., Kurata, T., Osawa, T. (Eds.), The Maillard Reaction in Food Chemistry and Medical Science: Update to the postgenomic era. ICS Elsevier Press, Amsterdam, NL 2002, pp. 313-320.
30. Somoza, V., Lindenmeier, M., Wenzel, E., Frank, O., et al., Activity-guided identification of a chemopreventive compound in coffee beverage using in vitro and in vivo techniques. J. Agric. Food Chem. 2003, 51, 6861-6869.
31. Daglia, M., Papetti, A., Gregotti, C., Berte, F., Gazzani, G., In vitro antioxidant and ex vivo protective activities of green and roasted coffee. J. Agric. Food Chem. 2000, 48, 1449-1454.
32. Cioroi, M., The Antioxidant Character of Melanoidins. Czech. J. Food Sci. 2000, 18, 103-105.
33. Steinhart, H., Luger, A., Piost, J., Antioxidative Effect of Coffee Melanoidins. Colloque Scientifique International sur le Cafe 19th 2001, 67-74.
34. Borrelli, R. C., Visconti, A., Mennella, C., Anese, M., Fogliano, V., Chemical characterization and antioxidant properties of coffee melanoidins. J. Agric. Food Chem. 2002, 50, 6527-6533.
35. Wagner, K.-H., Derkits, S., Herr, M., Schuh, W., Elmadfa, I., Antioxidative potential of melanoidins isolated from a roasted glucose-glycine model. Food Chem. 2002, 78, 375-382.
36. Morales, F. J., Jimenez-Perez, S., Peroxyl radical scavenging activity of melanoidins in aqueous systems. Eur. Food Research and Technol. 2004, 218, 515-520.
37. Valls-Bellés, V., Torres, M. C., Muñiz, P., Boix, L., et al., The protective effect of melanoidins in adriamycin-induced oxidative stress in rat isolated hepatocytes. J. Sci. Food Agric. 2004, 84, 1701-1707.
38. Esposito, F., Morisco, F., Verde, V., Ritieni, A., et al., Moderate coffee consumption increases plasma glutathione but not homocysteine in healthy subjects. Alimentary Pharmacology & Therapeutics 2003, 17, 595-601.
39. Brands, C. M., Alink, G. M., van Boekel, M. A., Jongen, W. M., Mutagenicity of heated sugar-casein systems: effect of the Maillard reaction. J. Agric. Food Chem. 2000, 48, 2271-2275.
40. Taylor, J. L., Demyttenaere, J. C., Abbaspour Tehrani, K., Olave, C. A., et al., Genotoxicity of melanoidin fractions derived from a standard glucose/glycine model. J. Agric. Food Chem. 2004, 52, 318-323.
41. Gloesl, S., Wagner, K. H., Draxler, A., Kaniak, M., et al., Genotoxicity and mutagenicity of melanoidins isolated from a roasted glucose-glycine model in human lymphocyte cultures, intestinal Caco-2 cells and in the Salmonella typhimurium strains TA98 and TA102 applying the AMES test. Food Chem. Toxicol. 2004, 42, 1487-1495.
42. Kim, S. B., Hayase, F., Kato, H., Desmutagenic effects of melanoidins against amino acid and protein pyrolysates. In: Fujimaki, M., Namiki, N., Kato, H. (Eds.), Amino-carbonyl-reactions in food and biological systems, Developments in Food Science 13, Elsevier, Tokyo 1986, pp. 383-392.
43. Pintauro, S. J., Lucchina, L. A., Effects of Maillard browned egg albumin on drug-metabolizing enzyme systems in the rat. Food Chem. Toxicol. 1987, 25, 369-372.
44. Marko, D., Habermeyer, M., Kemeny, M., Weyand, U., et al., Maillard reaction products modulating the growth of human tumor cells in vitro. Chem. Res. Toxicol. 2003, 16, 48-55.
45. De Bry, L., Anthropological implications of the Maillard reaction: An insight. In: Labuza, T. P., Reineccius, G. A., Monnier, V. M., O'Brien, J., Baynes, J. W. (Eds.), Maillard Reactions in Chemistry, Food and Health. The Royal Society of Chemistry, Cambridge 1994, pp. 28-36.
46. Monnier, V. M., Cerami, A., Nonenzymatic browning in vivo, possible process for aging of long-lived proteins. Science 1981, 211, 491-493.
47. Cerami, A., Hypothesis. Glucose as a mediator of aging. J. Am. Geriatr. Soc. 1985, 33, 626-634.
48. Forbes, J. M., Cooper, M. E., Oldfield, M. D., Thomas, M. C., Role of advanced glycation end products in diabetic nephropathy. J. Am. Soc. Nephrol. 2003, 14, 254-258.
49. Stitt, A. W., The role of advanced glycation in the pathogenesis of diabetic retinopathy. Exp. Mol. Pathol. 2003, 75, 95-108.
50. Stitt, A. W., Frizzell, N., Thorpe, S. R., Advanced glycation and advanced lipoxidation: possible role in initiation and progression of diabetic retinopathy. Curr. Pharmaceut. Design 2004, 10, 3349-3360.
51. Muench, G., Schinzel, R., Loske, C., Wong, A., et al., Alzheimer's disease - synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts. J. Neural. Transm. 1998, 105, 439-461.
52. Pischetsrieder, M., Seidel, W., Munch, G., Schinzel, R., N(2)-(1-Carboxyethyl)deoxyguanosine, a nonenzymatic glycation adduct of DNA, induces single-strand breaks and increases mutation frequencies. Biochem. Biophys. Res. Commun. 1999, 264, 544-549.
53. Ortega, M., et al., Protective effects of melanoidins on DNA damage: studies in vitro. In: Vegarud, G., Morales, F. (Eds.), Melanoidins in Food and Health, EC Directorate for Research 2003, Vol. 4, EUR 20722, pp. 189-194.
54. Januszewski, A. S., Alderson, N. L., Metz, T. O., Thorpe, S. R., Baynes, J. W., Role of lipids in chemical modification of proteins and development of complications in diabetes. Biochem. Soc. Trans. 2003, 31, 1413-1416.
55. Schmidt, A. M., Yan, S. D., Wautier, J. L., Stern, D., Activation of receptor for advanced glycation end products: a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis. Circ. Res. 1999, 84, 489-497.
56. Schmidt, A. M., Yan, S. D., Yan, S. F., Stern, D. M., The multi-ligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J. Clin. Invest. 2001, 108, 949-955.
57. Argirova, M. D., Breipohl, W., Glycated proteins can enhance photooxidative stress in aged and diabetic lenses. Free Radical. Res. 2002, 36, 1251-1259.
58. Zill, H., Bek, S., Hofmann, T., Huber, J., et al., RAGE-mediated MAPK activation by food-derived AGE and non-AGE products. Biochem. Biophys. Res. Comm. 2003, 300, 311-315.
59. Koschinsky, T., He, C.-J., Mitsuhashi, T., Bucala, R., et al., Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy. Proc. Natl. Acad. Sci. 1997, 94, 6474-6479.
60. Vlassara, H., Cai, W., Crandall, J., Goldberg, T., et al., Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy. Proc. Natl. Acad. Sci. USA 2002, 99, 15596-15601.
61. Sebekova, K., Krajcoviova-Kudlackova, M., Schinzel, R., Faist, V., et al., Plasma levels of advanced glycation end products in healthy, long-term vegetarians and subjects on a western mixed diet. Eur. J. Nutrition 2001, 40, 275-281.
62. Henle, T., AGEs in foods: do they play a role in uremia? Kidney Int. Suppl. 2003, 84, 145-147.
63. Sebekova, K., Faist, V., Hofmann, T., Schinzel, R., Heidland, A., Effects of a diet rich in advanced glycation end products in the rat remnant kidney model. Am. J. Kidney Dis. 41 Suppl. 2003, 1, 48-51.
64. Zheng, F., He, C., Cai, W., Hattori, M., et al., Prevention of diabetic nephropathy in mice by a diet low in glycoxidation products. Diabetes Metab. Res. Rev. 2002, 18, 224-237. Erratum in: Diabetes Metab. Res. Rev. 2002, 18, 332-339.
65. Muench, G., Food-derived Maillard reaction products - possible contributions to inflammatory processes in the brain. In: Fogliano, V., Henle, T. (Eds.), Melanoidins in Food and Health, EC Directorate for Research 2002, Vol. 3, pp. 224-226.