Metabolic transit and in vivo effects of melanoidins and precursor compounds deriving from the Maillard reaction

Annals of Nutrition and Metabolism

Volumn 45, Issue 1, 2001, Pages 1-12

  Faist, Veronika ^a   Erbersdobler, Helmut F ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

Maillard reaction products; Melanoidins; Metabolic transit

Indexed keywords

ADVANCED GLYCATION END PRODUCT; CARBON 14; FRUCTOSE LYSINE; MELANOIDINE; MICROBIAL ENZYME; PREMELANOIDIN; PROTEIN; SCHIFF BASE; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

AGING; BIOACCUMULATION; BIOTRANSFORMATION; DIGESTION; ENZYME ACTIVATION; ENZYME ACTIVITY; FECES; FOOD INTAKE; GLYCATION; HEAT TREATMENT; HUMAN; INTESTINE ABSORPTION; METABOLISM; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; RADIOACTIVITY; REACTION ANALYSIS; REVIEW; STRUCTURE ACTIVITY RELATION; URINARY EXCRETION; XENOBIOTIC METABOLISM;

AMINO ACIDS; ANIMALS; FRUCTOSE; HUMANS; LYSINE; MAILLARD REACTION; POLYMERS; RATS;

ANIMALIA;

EID: 0035104096     PISSN: 02506807     EISSN: None     Source Type: Journal    
DOI: 10.1159/000046699     Document Type: Review

References (86)

1. Nutritional and physiological consequences of the Maillard reaction
2. Antioxidative activity of nonenzymatically browned proteins produced in oxidized lipid/protein reactions
3. The effect of a model melanoidin mixture on faecel bacterial populations in vitro
4. Interactions between Maillard's reaction products, the microflora of the digestive tract and mineral metabolism
5. Effects of Maillard's reaction products on apparent mineral absorption in different parts of the digestive tract: The role of microflora
6. The Linxian trials: Mortality rates by vitamin-mineral intervention group
7. Glutathione S-transferase subunit induction patterns of brussels sprouts, allyl isothiocyanate and goitrin in rat liver and small intestinal mucosa: A new approach for the identification of inducing xenobiotics
8. Mutagenicity of heated sugar-casein systems: Effect of the Maillard Reaction
9. Advanced protein glycosylation in diabetes and aging
10. Untersuchungen zur analytischen und physiologischen Charakterisierung der Aminosäurenschädigung bei Hitzebehandlung von Nahrungs- und Futtermitteln
11. Anthropological implications of the Maillard reaction: An insight
12. Determination of carboxymethyllysine in milk products by a modified reversed-phase-HPLC method
13. Untersuchungen zur analytischen und physiologischen Charakterisierung der Aminosäurenschädigung bei Hitzebehandlung
14. Abbau von Fruktoselysin durch die Darmflora
15. The biological significance of carbohydrate-lysine crosslinks during heat-treatment of food proteins
16. Transport and metabolism studies with fructose amino acids
17. Urinary excretion of fructoselysine in human volunteers and diabetic patients
18. Absorption and metabolism of heated protein-carbohydrate mixtures in humans
19. Untersuchungen zur analytischen und physiologischen Charakterisierung der Aminosäurenschädigung
20. Tissue specific induction of phase I and II xenobiotic enzymes and oxygen free radical metabolism in rats fed alkali-treated protein containing high levels of lysinolanine
21. Aging, metabolism and Alzheimer's disease: Review and hypotheses
22. Chemical modifications of the milk proteins during processing and storage. Nutritional, metabolic and physiological consequences
23. Metabolism and physiological effects of Maillard reaction products
24. Metabolic transit and toxicity of Maillard reaction products
25. Metabolic transit of early and advanced Maillard products
26. Modification of urinary zinc excretion in the rat associated with the feeding of Maillard reaction products
27. Novel degradation pathway of glycated amino acids into free fructosamine by a Pseudomonas sp. soil strain extract
28. 14C]-5-hydroxymethyl-2-furaldehyde administered orally or intravenously to rats
29. Scavenging of active oxygens by melanoidin
30. Dietary glycotoxins. Inhibition of reactive products by aminoguanidine facilitates renal clearance and reduces tissue sequestration
31. 4H-pyran-4-one (DDMP), a Maillard reaction product of glucose and glycine
32. Chemistry of browning reactions in model systems
33. Growth response of rats fed a diet containing nondialyzable melanoidin
34. Effects of browning products on the intestinal microflora of the rat
35. Chemistry, formation and occurrence of genotoxic heterocyclic amines identified in model systems and cooked foods
36. The Maillard reaction in foods
37. 2-Oxoaldehyde metabolising enzymes in animal tissues
38. Metabolism of 3-deoxyglucosone, an intermediate compound in the Maillard reaction, administered orally or intravenously to rats
39. Desmutagenic effects of melanoidins against amino acid and protein pyrolysates
40. Long-term feeding effects of browned egg albumin to rats
41. Effect of glucose-lysine Maillard reaction products fractions on tissue xenobiotic enzyme systems
42. Effect of diabetes and aging on carboxymethyllysine levels in human urine
43. Dietary modifiers of carcinogenesis
44. Orally absorbed reactive glycation products (glycotoxins): An environmental risk factor in diabetic retinopathy
45. Chemical pathways of the Maillard reaction
46. Physiological and safety aspects of Maillard browning of foods
47. Balance experiments on human volunteers with ε fructoselysine (FL) and lysinoalanine (LAL)
48. ε-carboxymethyllysine: A new Maillard reaction product in rat urine
49. Antioxidative effect of Maillard reaction products
50. The Maillard reaction in food: A critical review from the nutritional standpoint
51. Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus
52. Maillard reaction-mediated molecular damage to extracellular matrix and other tissue proteins in diabetes, aging, and uremia
53. 14C-L-lysine labeled casein browned by amino-carbonyl reaction
54. Alzheimer's disease-synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts
55. Absorption and distribution of a C14-glucose lysine reaction mixture in the rat
56. High molecular weight hyaluronic acid inhibits advanced glycation endproduct-induced NF-kappaB activation and cytokine expression
57. ε-L-deoxyfructosyl-lysine in urine after ingestion of a lactose-free, glucose-containing milk formula
58. Nutritional and toxicological aspects of the Maillard browning reaction in foods
59. Toxicological effects of dietary Maillard reaction products in the rat
60. Effect of Maillard reaction products on protein digestion: In vitro studies
61. Effect of Maillard reaction products on protein digestion. Studies on pure compounds
62. Physiological, toxicological and nutritional aspects of various Maillard browned products
63. Effects of Maillard browned egg albumin on drug-metabolizing enzyme systems in the rat
64. Browning reaction systems as sources of mutagens and antimutagens
65. Clastrogenic and mutagenic activities of Maillard reaction model systems
66. Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver
67. Effect of Maillard reaction products on bile acid binding, plasma and hepatic lipids and weight of gastrointestinal organs
68. The effects of antioxidants on the metabolism and mutagenicity of benzo[a]pyrene in vitro
69. Influence of age and long-term dietary restriction on enzymatically mediated crosslinks and nonenzymatic glycation of collagen in mice
70. Nutritional consequences of the Maillard reaction. Amino acid bioavailability from fructose-leucine and fructose-tryptophan in the rat
71. Cellular receptor for advanced glycation end products: Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions
72. Pan-fried meat containing high levels of heterocyclic aromatic amines but low levels of polycyclic aromatic hydrocarbons induces cytochrome P4501A2 activity in humans
73. Carcinogenic heterocyclic amines in model systems and cooked foods: A review on formation, occurrence and intake
74. Nutritional consequences on the Maillard reaction: The absorption of fructose-L-tryptophan in the large intestine of the rat
75. Cell activation by glycated proteins. AGE receptors, receptor recognition factors and functional classification of AGEs
76. Digestion of heat-damaged egg albumen by the rat
77. Accumulation of diabetic rat peripheral nerve myelin by macrophages increases with extent and duration of non-enzymatic glycosylation
78. Recognition and uptake of human diabetic peripheral nerve myelin by macrophages
79. Novel macrophage receptor for glucose-modified proteins is distinct from previously described scavenger receptors
80. Mechanisms of macronutrient carcinogenesis
81. Mechanism of autoxidative glycosylation - Identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose
82. ε-Carboxymethyllysine auf die NADPH-Cytochrom c-Reduktase und die Glutathion-S-Transferase in vitro und in vivo
83. ε-carboxymethyllysine, a constituent of human urine
84. Enhanced cellular oxidant stress by the interaction of advanced glycation and products with their receptors/binding proteins
85. Antioxidative effect of Maillard reaction products using glucose-glycine model system
86. Formation of reactive intermediates from Amadori compounds and physiological conditions