-
1
-
-
0032575688
-
The Bcl-2 protein family: Abiters of cell survival
-
Adams JM and Cory S (1998) The Bcl-2 protein family: arbiters of cell survival. Science 281: 1322-1326
-
(1998)
Science
, vol.281
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
2
-
-
0036716281
-
The Bcl2 family: Regulators of the cellular life-or-death switch
-
Cory S and Adams JM (2002) The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2: 647-656
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
4
-
-
0034786019
-
BCL-2, BCL-XL sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
-
Cheng EH, Wei M, Weiler S, Flavell RA, Mak TW, Lindsten T and Korsmeyer SJ (2001) BCL-2, BCL-XL sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol. Cell 8: 705-711
-
(2001)
Mol. Cell
, vol.8
, pp. 705-711
-
-
Cheng, E.H.1
Wei, M.2
Weiler, S.3
Flavell, R.A.4
Mak, T.W.5
Lindsten, T.6
Korsmeyer, S.J.7
-
5
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S and Korsmeyer SJ (2002) Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2: 183-192
-
(2002)
Cancer Cell
, vol.2
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
Sorcinelli, M.D.4
Weiler, S.5
Korsmeyer, S.J.6
-
6
-
-
19944432123
-
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
-
Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL, Adams JM and Huang DCS (2005) Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol. Cell 17: 393-403
-
(2005)
Mol. Cell
, vol.17
, pp. 393-403
-
-
Chen, L.1
Willis, S.N.2
Wei, A.3
Smith, B.J.4
Fletcher, J.I.5
Hinds, M.G.6
Colman, P.M.7
Day, C.L.8
Adams, J.M.9
Huang, D.C.S.10
-
7
-
-
0036726059
-
BH3 domains: Intracellular death-ligands critical for initiating apoptosis
-
Chittenden T (2002) BH3 domains: intracellular death-ligands critical for initiating apoptosis. Cancer Cell 2: 165-166
-
(2002)
Cancer Cell
, vol.2
, pp. 165-166
-
-
Chittenden, T.1
-
8
-
-
4444291734
-
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix
-
Walensky LD, Kung AL, Escher I, Malia TJ, Barbuto S, Wright RD, Wagner G, Verdine GL and Korsmeyer SJ (2004) Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix. Science 305: 1466-1470
-
(2004)
Science
, vol.305
, pp. 1466-1470
-
-
Walensky, L.D.1
Kung, A.L.2
Escher, I.3
Malia, T.J.4
Barbuto, S.5
Wright, R.D.6
Wagner, G.7
Verdine, G.L.8
Korsmeyer, S.J.9
-
9
-
-
0031930688
-
Modulation of cell death by Bcl-xL through caspase interaction
-
Clem RJ, Cheng EH, Karp CL, Kirsch DG, Ueno K, Takahashi A, Kastan MB, Griffin DE, Earnshaw WC, Veliuona MA and Hardwick JM (1998) Modulation of cell death by Bcl-xL through caspase interaction. Proc. Natl. Acad. Sci. USA 95: 554-559
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 554-559
-
-
Clem, R.J.1
Cheng, E.H.2
Karp, C.L.3
Kirsch, D.G.4
Ueno, K.5
Takahashi, A.6
Kastan, M.B.7
Griffin, D.E.8
Earnshaw, W.C.9
Veliuona, M.A.10
Hardwick, J.M.11
-
10
-
-
0031465443
-
Conversion of Bcl-2 to a Bax-like death effector by caspases
-
Cheng EH, Kirsch DG, Clem RJ, Ravi R, Kastan MB, Bedi A, Ueno K and Hardwick JM (1997) Conversion of Bcl-2 to a Bax-like death effector by caspases. Science 278: 1966-1968
-
(1997)
Science
, vol.278
, pp. 1966-1968
-
-
Cheng, E.H.1
Kirsch, D.G.2
Clem, R.J.3
Ravi, R.4
Kastan, M.B.5
Bedi, A.6
Ueno, K.7
Hardwick, J.M.8
-
11
-
-
0034698878
-
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
-
Nakagawa T and Yuan J (2000) Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J. Cell Biol. 150: 887-894
-
(2000)
J. Cell Biol.
, vol.150
, pp. 887-894
-
-
Nakagawa, T.1
Yuan, J.2
-
12
-
-
0033956278
-
Calpain or caspase: Can you tell the difference?
-
Wang K (2000) Calpain or caspase: can you tell the difference? Trends Neurosci. 23: 20-26
-
(2000)
Trends Neurosci.
, vol.23
, pp. 20-26
-
-
Wang, K.1
-
13
-
-
0033213973
-
Caspase and calpain substrates: Roles in synaptic plasticity and cell death
-
Chan SL and Mattson MP (1999) Caspase and calpain substrates: roles in synaptic plasticity and cell death. J. Neurosci. Res. 58: 167-190
-
(1999)
J. Neurosci. Res.
, vol.58
, pp. 167-190
-
-
Chan, S.L.1
Mattson, M.P.2
-
14
-
-
0028824266
-
A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow
-
Choi SS, Park I-C, Yun JW, Sung YC, Hong S-I and Shin H-S (1995) A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow. Oncogene 11: 1693-1698
-
(1995)
Oncogene
, vol.11
, pp. 1693-1698
-
-
Choi, S.S.1
Park, I.-C.2
Yun, J.W.3
Sung, Y.C.4
Hong, S.-I.5
Shin, H.-S.6
-
15
-
-
0027326012
-
Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2
-
Lin EY, Orlofsky A, Berger MS and Prystowsky MB (1993) Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2. J. Immunol. 151: 1979-1988
-
(1993)
J. Immunol.
, vol.151
, pp. 1979-1988
-
-
Lin, E.Y.1
Orlofsky, A.2
Berger, M.S.3
Prystowsky, M.B.4
-
16
-
-
0033575142
-
NH2-terminal BH4 domain of Bcl-2 is functional for heterodimerization with Bax and inhibition of apoptosis
-
Hirotani M, Zhang Y, Fujita N, Naito M and Tsuruo T (1999) NH2-terminal BH4 domain of Bcl-2 is functional for heterodimerization with Bax and inhibition of apoptosis. J. Biol. Chem. 274: 20415-20420
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20415-20420
-
-
Hirotani, M.1
Zhang, Y.2
Fujita, N.3
Naito, M.4
Tsuruo, T.5
-
17
-
-
0034646702
-
Structural basis of Bfl-1 for its interaction with Bax and anti-apoptotic action in mammalian and yeast cells
-
Zhang H, Cowan-Jacob SW, Simonen M, Greenhalf W, Heim J and Meyhack B (2000) Structural basis of Bfl-1 for its interaction with Bax and anti-apoptotic action in mammalian and yeast cells. J. Biol. Chem. 275: 11092-11099
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 11092-11099
-
-
Zhang, H.1
Cowan-Jacob, S.W.2
Simonen, M.3
Greenhalf, W.4
Heim, J.5
Meyhack, B.6
-
18
-
-
0029097470
-
Multiple Bcl-2 family members demonstrate selective dimerizations with Bax
-
(a)
-
(a) Sedlak TW, Oltvai ZN, Yang E, Wang K, Boise LH, Thompson CB and Korsmeyer SJ (1995) Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc. Natl. Acad. Sci. USA 92: 7834-7838
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7834-7838
-
-
Sedlak, T.W.1
Oltvai, Z.N.2
Yang, E.3
Wang, K.4
Boise, L.H.5
Thompson, C.B.6
Korsmeyer, S.J.7
-
19
-
-
0032543597
-
Functional dissection of Bfl-1, a Bcl-2 homolog: Anti-apoptosis, oncogene-cooperation and cell proliferation activities
-
D'Sa-Eipper C and Chirmadurai G (1998) Functional dissection of Bfl-1, a Bcl-2 homolog: anti-apoptosis, oncogene-cooperation and cell proliferation activities. Oncogene 16: 3105-3114
-
(1998)
Oncogene
, vol.16
, pp. 3105-3114
-
-
D'Sa-Eipper, C.1
Chirmadurai, G.2
-
20
-
-
0031920881
-
Multiple gene duplication and expression of mouse bcl-2-related genes, A1
-
Hatakeyama S, Hamasaki A, Negishi I, Loh DY, Sendo F and Nakayama K (1998) Multiple gene duplication and expression of mouse bcl-2-related genes, A1. Int. Immunol. 10: 631-637
-
(1998)
Int. Immunol.
, vol.10
, pp. 631-637
-
-
Hatakeyama, S.1
Hamasaki, A.2
Negishi, I.3
Loh, D.Y.4
Sendo, F.5
Nakayama, K.6
-
21
-
-
0037693201
-
Bfl-1S, a novel alternative splice variant of Bfl-1, localizes in the nucleus via its C-terminus and prevents cell death
-
Ko JK, Lee MJ, Cho SH, Cho JA, Lee BY, Koh JS, Lee SS, Shim YH and Kim CW (2003) Bfl-1S, a novel alternative splice variant of Bfl-1, localizes in the nucleus via its C-terminus and prevents cell death. Oncogene 22: 2457-2465
-
(2003)
Oncogene
, vol.22
, pp. 2457-2465
-
-
Ko, J.K.1
Lee, M.J.2
Cho, S.H.3
Cho, J.A.4
Lee, B.Y.5
Koh, J.S.6
Lee, S.S.7
Shim, Y.H.8
Kim, C.W.9
-
22
-
-
0030952952
-
GRS, a novel member of the Bcl-2 gene family, is highly expressed in multiple cancer cell lines and in normal leukocytes
-
Kenny JJ, Knobloch TJ, Augustus M, Carter KC, Rosen CA and Lang JC (1997) GRS, a novel member of the Bcl-2 gene family, is highly expressed in multiple cancer cell lines and in normal leukocytes. Oncogene 14: 997-1001
-
(1997)
Oncogene
, vol.14
, pp. 997-1001
-
-
Kenny, J.J.1
Knobloch, T.J.2
Augustus, M.3
Carter, K.C.4
Rosen, C.A.5
Lang, J.C.6
-
23
-
-
0033558215
-
The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis
-
Zong WX, Edelstein LC, Chen C, Bash J and Gélinas C (1999) The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis. Genes Dev. 13: 382-387
-
(1999)
Genes Dev.
, vol.13
, pp. 382-387
-
-
Zong, W.X.1
Edelstein, L.C.2
Chen, C.3
Bash, J.4
Gélinas, C.5
-
24
-
-
0032531994
-
Lipopolysaccharide induces the antiapoptotic molecules, A1 and A20, in microvascular endothelial cells
-
Hu X, Yee E, Harlan JM, Wong F and Karsan A (1998) Lipopolysaccharide induces the antiapoptotic molecules, A1 and A20, in microvascular endothelial cells. Blood 92: 2759-2765
-
(1998)
Blood
, vol.92
, pp. 2759-2765
-
-
Hu, X.1
Yee, E.2
Harlan, J.M.3
Wong, F.4
Karsan, A.5
-
25
-
-
0033529416
-
NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes
-
Lee HH, Dadgostar H, Cheng Q, Shu J and Cheng G (1999) NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes. Proc. Natl. Acad. Sci. USA 96: 9136-9141
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9136-9141
-
-
Lee, H.H.1
Dadgostar, H.2
Cheng, Q.3
Shu, J.4
Cheng, G.5
-
26
-
-
0032588317
-
NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis
-
Wang CY, Guttridge DC, Mayo MW and Baldwin Jr AS (1999) NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis. Mol. Cell. Biol. 19: 5923-5929
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 5923-5929
-
-
Wang, C.Y.1
Guttridge, D.C.2
Mayo, M.W.3
Baldwin Jr., A.S.4
-
27
-
-
0033557805
-
Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis
-
Grumont RJ, Rourke IJ and Gerondakis S (1999) Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis. Genes Dev. 13: 400-411
-
(1999)
Genes Dev.
, vol.13
, pp. 400-411
-
-
Grumont, R.J.1
Rourke, I.J.2
Gerondakis, S.3
-
28
-
-
0037384877
-
NF-κB-dependent assembly of an enhanceosome-like complex on the promoter region of apoptosis inhibitor Bf1-1/A1
-
(a)
-
(a) Edelstein LC, Lagos L, Simmons M, Tirumalai H and Gélinas C (2003) NF-κB-dependent assembly of an enhanceosome-like complex on the promoter region of apoptosis inhibitor Bf1-1/A1, Mol. Cell. Biol. 23: 2749-2761
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 2749-2761
-
-
Edelstein, L.C.1
Lagos, L.2
Simmons, M.3
Tirumalai, H.4
Gélinas, C.5
-
29
-
-
0034908490
-
Transient expression of the Bcl-2 family member, A1-a, results in nuclear localization and resistance to staurosporine-induced apoptosis
-
Somogyi RD, Wu Y, Orlofsky A and Prystowsky MB (2001) Transient expression of the Bcl-2 family member, A1-a, results in nuclear localization and resistance to staurosporine-induced apoptosis. Cell Death Diff. 8: 785-793
-
(2001)
Cell Death Diff.
, vol.8
, pp. 785-793
-
-
Somogyi, R.D.1
Wu, Y.2
Orlofsky, A.3
Prystowsky, M.B.4
-
30
-
-
0037151030
-
Bcl-2 family member Bfl-1/A1 sequesters truncated Bid to inhibit its collaboration with pro-apoptotic Bak or Bax
-
Werner AB, de Vries E, Tait SWG, Bontjer I and Borst J (2002) Bcl-2 family member Bfl-1/A1 sequesters truncated Bid to inhibit its collaboration with pro-apoptotic Bak or Bax. J. Biol. Chem. 277: 22781-22788
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 22781-22788
-
-
Werner, A.B.1
de Vries, E.2
Tait, S.W.G.3
Bontjer, I.4
Borst, J.5
-
31
-
-
0029815941
-
Bfl-1, a Bcl-2 homologue, suppresses p53-induced apoptosis and exhibits potent cooperative transforming activity
-
D'Sa-Eipper C, Subramanian T and Chinnadurai G (1996) Bfl-1, a Bcl-2 homologue, suppresses p53-induced apoptosis and exhibits potent cooperative transforming activity. Cancer Res. 56: 3879-3882
-
(1996)
Cancer Res.
, vol.56
, pp. 3879-3882
-
-
D'Sa-Eipper, C.1
Subramanian, T.2
Chinnadurai, G.3
-
32
-
-
0029861518
-
Endothelial cell death induced by tumor necrosis factor-alpha is inhibited by the Bcl-2 family member, A1
-
Karsan A, Yee E and Harlan JM (1996) Endothelial cell death induced by tumor necrosis factor-alpha is inhibited by the Bcl-2 family member, A1. J. Biol. Chem. 271: 27201-27204
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27201-27204
-
-
Karsan, A.1
Yee, E.2
Harlan, J.M.3
-
33
-
-
0036140941
-
Role of caspase-3-dependent Bcl-2 cleavage in potentiation of apoptosis by Bcl-2
-
Liang Y, Nylander KD, Yan C and Schor NF (2002) Role of caspase-3-dependent Bcl-2 cleavage in potentiation of apoptosis by Bcl-2. Mol. Pharmacol. 61: 142-149
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 142-149
-
-
Liang, Y.1
Nylander, K.D.2
Yan, C.3
Schor, N.F.4
-
34
-
-
0033597785
-
Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c
-
Kirsch DG, Doseff A, Chau BN, Lim DS, de Souza-Pinto NC, Hansford R, Kastan MB, Lazebnik YA and Hardwick JM (1999) Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c. J. Biol. Chem. 274: 21155-21161
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21155-21161
-
-
Kirsch, D.G.1
Doseff, A.2
Chau, B.N.3
Lim, D.S.4
de Souza-Pinto, N.C.5
Hansford, R.6
Kastan, M.B.7
Lazebnik, Y.A.8
Hardwick, J.M.9
-
35
-
-
0033603460
-
Bcl-2 and caspase inhibition cooperate to inhibit tumor necrosis factor-alpha-induced cell death in a Bcl-2 cleavage-independent fashion
-
Johnson BW and Boise LH (1999) Bcl-2 and caspase inhibition cooperate to inhibit tumor necrosis factor-alpha-induced cell death in a Bcl-2 cleavage-independent fashion. J. Biol. Chem. 274: 18552-18558
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18552-18558
-
-
Johnson, B.W.1
Boise, L.H.2
-
36
-
-
0027980319
-
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
-
Rock KL, Gramm C, Rothstein L, Clark K, Stein R, Dick L, Hwang D and Goldberg AL (1994) Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78: 761-771
-
(1994)
Cell
, vol.78
, pp. 761-771
-
-
Rock, K.L.1
Gramm, C.2
Rothstein, L.3
Clark, K.4
Stein, R.5
Dick, L.6
Hwang, D.7
Goldberg, A.L.8
-
37
-
-
0032541565
-
Stress-activated kinases regulate protein stability
-
Fuchs SY, Fried VA and Ronai Z (1998) Stress-activated kinases regulate protein stability. Oncogene 17: 1483-1490
-
(1998)
Oncogene
, vol.17
, pp. 1483-1490
-
-
Fuchs, S.Y.1
Fried, V.A.2
Ronai, Z.3
-
38
-
-
0036236471
-
Calpain-mediated Bid cleavage and calpain-independent Bak modulation: Two separate pathways in cisplatin-induced apoptosis
-
Mandic A, Viktorsson K, Strandberg L, Heiden T, Hansson J, Linder S and Shoshan MC (2002) Calpain-mediated Bid cleavage and calpain-independent Bak modulation: two separate pathways in cisplatin-induced apoptosis. Mol. Cell. Biol. 22: 3003-3013
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 3003-3013
-
-
Mandic, A.1
Viktorsson, K.2
Strandberg, L.3
Heiden, T.4
Hansson, J.5
Linder, S.6
Shoshan, M.C.7
-
39
-
-
0032480260
-
Bax cleavage is mediated by calpain during drug-induced apoptosis
-
Wood DE, Thomas A, Devi LA, Berman Y, Beavis RC, Reed JC and Newcomb EW (1998) Bax cleavage is mediated by calpain during drug-induced apoptosis. Oncogene 17: 1069-1078
-
(1998)
Oncogene
, vol.17
, pp. 1069-1078
-
-
Wood, D.E.1
Thomas, A.2
Devi, L.A.3
Berman, Y.4
Beavis, R.C.5
Reed, J.C.6
Newcomb, E.W.7
-
40
-
-
0034967241
-
Cleavage of Bax is mediated by caspase-dependent or - Independent calpain activation in dopaminergic neuronal cells: Protective role of Bcl-2
-
Choi WS, Lee EH, Chung CW, Jung YK, Jin BK, Kim SU, Oh TH, Saido TC and Oh YJ (2001) Cleavage of Bax is mediated by caspase-dependent or - independent calpain activation in dopaminergic neuronal cells: protective role of Bcl-2. J. Neurochem. 77: 1531-1541
-
(2001)
J. Neurochem.
, vol.77
, pp. 1531-1541
-
-
Choi, W.S.1
Lee, E.H.2
Chung, C.W.3
Jung, Y.K.4
Jin, B.K.5
Kim, S.U.6
Oh, T.H.7
Saido, T.C.8
Oh, Y.J.9
-
41
-
-
0030726132
-
Specificities of cell permeant peptidyl inhibitors for the proteinase activities of μ-calpain and the 20S proteasome
-
Mellgren RL (1997) Specificities of cell permeant peptidyl inhibitors for the proteinase activities of μ-calpain and the 20S proteasome. J. Biol. Chem. 272: 29899-29903
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 29899-29903
-
-
Mellgren, R.L.1
-
42
-
-
0028800908
-
Serine and cysteine proteinase inhibitors prevent nitric oxide production by activated macrophages by interfering with transcription of the inducible NO synthase gene
-
Griscavage JM, Wilk S and Ignarro LJ (1995) Serine and cysteine proteinase inhibitors prevent nitric oxide production by activated macrophages by interfering with transcription of the inducible NO synthase gene. Biochem. Biophys. Res. Commun. 215: 721-729
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.215
, pp. 721-729
-
-
Griscavage, J.M.1
Wilk, S.2
Ignarro, L.J.3
-
43
-
-
0034674551
-
A1 functions at the mitochondria to delay endothelial apoptosis in response to tumor necrosis factor
-
Duriez PJ, Wong F, Dorovini-Zis K, Shahidi R and Karsan A (2000) A1 functions at the mitochondria to delay endothelial apoptosis in response to tumor necrosis factor. J. Biol. Chem. 275: 18099-18107
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18099-18107
-
-
Duriez, P.J.1
Wong, F.2
Dorovini-Zis, K.3
Shahidi, R.4
Karsan, A.5
-
44
-
-
0142070961
-
Conversion of Bfl-1, an anti-apoptotic Bcl-2 family protein, to a potent pro-apoptotic protein by fusion with green fluorescent protein (GFP)
-
Ko JK, Choi KH, Kim HJ, Choi HY, Yeo DJ, Park SO, Yang WS, Kim YN and Kim CW (2003) Conversion of Bfl-1, an anti-apoptotic Bcl-2 family protein, to a potent pro-apoptotic protein by fusion with green fluorescent protein (GFP). FEBS Lett. 551: 29-36
-
(2003)
FEBS Lett.
, vol.551
, pp. 29-36
-
-
Ko, J.K.1
Choi, K.H.2
Kim, H.J.3
Choi, H.Y.4
Yeo, D.J.5
Park, S.O.6
Yang, W.S.7
Kim, Y.N.8
Kim, C.W.9
-
45
-
-
0348014686
-
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
-
Cuconati A, Mukherjee C, Perez D and White E (2003) DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells. Genes Dev. 17: 2922-2932
-
(2003)
Genes Dev.
, vol.17
, pp. 2922-2932
-
-
Cuconati, A.1
Mukherjee, C.2
Perez, D.3
White, E.4
-
46
-
-
0038046166
-
Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation
-
Nijhawan D, Fang M, Traer E, Zhong Q, Gao W, Du F and Wang X (2003) Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation. Genes Dev. 17: 1475-1486
-
(2003)
Genes Dev.
, vol.17
, pp. 1475-1486
-
-
Nijhawan, D.1
Fang, M.2
Traer, E.3
Zhong, Q.4
Gao, W.5
Du, F.6
Wang, X.7
-
47
-
-
0033532543
-
Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: A link between the apoptosome and the proteasome pathway
-
Dimmeler S, Breitschopf K, Haendeler J and Zeiher AM (1999) Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway. J. Exp. Med. 189: 1815-1822
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1815-1822
-
-
Dimmeler, S.1
Breitschopf, K.2
Haendeler, J.3
Zeiher, A.M.4
-
48
-
-
0033974063
-
Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: Molecular characterization of the involved signaling pathway
-
Breitschopf K, Haendeler J, Malchow P, Zeiher AM and Dimmeler S (2000) Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway. Mol. Cell. Biol. 20: 1886-1896
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1886-1896
-
-
Breitschopf, K.1
Haendeler, J.2
Malchow, P.3
Zeiher, A.M.4
Dimmeler, S.5
-
49
-
-
0347089015
-
Mono- and multisite phosphorylation enhances Bcl-2's antiapoptotic function and inhibition of cell cycle entry functions
-
Deng X, Gao F, Flagg T and May WS (2004) Mono- and multisite phosphorylation enhances Bcl-2's antiapoptotic function and inhibition of cell cycle entry functions. Proc. Natl. Acad. Sci. USA 101: 153-158
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 153-158
-
-
Deng, X.1
Gao, F.2
Flagg, T.3
May, W.S.4
-
50
-
-
0038337815
-
The calpain system
-
Goll DE, Thompson VF, Li H, Wei W and Cong J (2003) The calpain system. Physiol. Rev. 83: 731-801
-
(2003)
Physiol. Rev.
, vol.83
, pp. 731-801
-
-
Goll, D.E.1
Thompson, V.F.2
Li, H.3
Wei, W.4
Cong, J.5
-
51
-
-
0033568430
-
Implication of calpain in caspase activation during B cell clonal deletion
-
Ruiz-Vela A, Gonzalez de Buitrago G and Martinez AC (1999) Implication of calpain in caspase activation during B cell clonal deletion. EMBO J. 18: 4988-4998
-
(1999)
EMBO J.
, vol.18
, pp. 4988-4998
-
-
Ruiz-Vela, A.1
Gonzalez de Buitrago, G.2
Martinez, A.C.3
-
52
-
-
0033199115
-
Calpain functions in a caspase-independent manner to promote apoptosis-like events during platelet activation
-
Wolf BB, Goldstein JC, Beere H, Amarante-Mentes GP, Salvesen GS and Green DR (1999) Calpain functions in a caspase-independent manner to promote apoptosis-like events during platelet activation. Blood 94: 1683-1692
-
(1999)
Blood
, vol.94
, pp. 1683-1692
-
-
Wolf, B.B.1
Goldstein, J.C.2
Beere, H.3
Amarante-Mentes, G.P.4
Salvesen, G.S.5
Green, D.R.6
-
53
-
-
0001110114
-
Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases
-
Chua BT, Guo K and Li P (2000) Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases. J. Biol. Chem. 275: 5131-5135
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5131-5135
-
-
Chua, B.T.1
Guo, K.2
Li, P.3
-
54
-
-
0033575926
-
Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates
-
McGinnis KM, Gnegy ME, Park YH, Mukerjee N and Wang KK (1999) Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates. Biochem. Biophys. Res. Commun. 263: 94-99
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.263
, pp. 94-99
-
-
McGinnis, K.M.1
Gnegy, M.E.2
Park, Y.H.3
Mukerjee, N.4
Wang, K.K.5
-
55
-
-
0041018181
-
Cleavage of the calpain inhibitor, calpastatin, during apoptosis
-
Porn-Ares MI, Samali A and Orrenius S (1998) Cleavage of the calpain inhibitor, calpastatin, during apoptosis. Cell Death Differ. 5: 1028-1033
-
(1998)
Cell Death Differ.
, vol.5
, pp. 1028-1033
-
-
Porn-Ares, M.I.1
Samali, A.2
Orrenius, S.3
-
56
-
-
0032529621
-
Caspase-mediated fragmentation of calpain inhibitor protein calpastatin during apoptosis
-
Wang KK, Posmantur R, Nadimpalli R, Nath R, Mohan P, Nixon RA, Talanian RV, Keegan M, Herzog L and Allen H (1998) Caspase-mediated fragmentation of calpain inhibitor protein calpastatin during apoptosis. Arch. Biochem. Biophys. 356: 187-196
-
(1998)
Arch. Biochem. Biophys.
, vol.356
, pp. 187-196
-
-
Wang, K.K.1
Posmantur, R.2
Nadimpalli, R.3
Nath, R.4
Mohan, P.5
Nixon, R.A.6
Talanian, R.V.7
Keegan, M.8
Herzog, L.9
Allen, H.10
-
57
-
-
0028088153
-
Calpain: New perspectives in molecular diversity and physiological-pathological involvement
-
Saido TC, Sorimachi H and Suzuki K (1994) Calpain: new perspectives in molecular diversity and physiological-pathological involvement. FASEB J. 8: 814-822
-
(1994)
FASEB J.
, vol.8
, pp. 814-822
-
-
Saido, T.C.1
Sorimachi, H.2
Suzuki, K.3
-
58
-
-
1242316976
-
Calpain-1 regulates Bax and subsequent Smac-dependent caspase-3 activation in neutrophil apoptosis
-
Altznauer F, Conus S, Cavalli A, Folkers G and Simon HU (2004) Calpain-1 regulates Bax and subsequent Smac-dependent caspase-3 activation in neutrophil apoptosis. J. Biol. Chem. 279: 5947-5957
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5947-5957
-
-
Altznauer, F.1
Conus, S.2
Cavalli, A.3
Folkers, G.4
Simon, H.U.5
-
59
-
-
0028105796
-
Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes
-
Merino R, Ding L, Veis DJ, Korsmeyer SJ and Nunez G (1994) Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes. EMBO J. 13: 683-691
-
(1994)
EMBO J.
, vol.13
, pp. 683-691
-
-
Merino, R.1
Ding, L.2
Veis, D.J.3
Korsmeyer, S.J.4
Nunez, G.5
-
60
-
-
0029932478
-
A day in the life of the Bcl-2 protein: Does the turnover rate of Bcl-2 serve as a biological clock for cellular lifespan regulation?
-
Reed JC (1996) A day in the life of the Bcl-2 protein: does the turnover rate of Bcl-2 serve as a biological clock for cellular lifespan regulation? Leuk. Res. 20: 109-111
-
(1996)
Leuk. Res.
, vol.20
, pp. 109-111
-
-
Reed, J.C.1
-
61
-
-
0032505124
-
Acceleration of apoptotic cell death after cleavage of Bcl-xL protein by caspase-3-like proteases
-
Fujita N, Nagahashi A, Nagashima K, Rokudai S and Tsuruo T (1998) Acceleration of apoptotic cell death after cleavage of Bcl-xL protein by caspase-3-like proteases. Oncogene 17: 1295-1304
-
(1998)
Oncogene
, vol.17
, pp. 1295-1304
-
-
Fujita, N.1
Nagahashi, A.2
Nagashima, K.3
Rokudai, S.4
Tsuruo, T.5
-
63
-
-
0023003536
-
The involvement of calpain in the activation of protein kinase C in neutrophils stimulated by phorbol myrstic acid
-
Melloni E, Pontremoli S, Michetti M, Sacco O, Sparatore B and Horecker BL (1986) The involvement of calpain in the activation of protein kinase C in neutrophils stimulated by phorbol myrstic acid. J. Biol. Chem. 261: 4101-4105
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 4101-4105
-
-
Melloni, E.1
Pontremoli, S.2
Michetti, M.3
Sacco, O.4
Sparatore, B.5
Horecker, B.L.6
-
64
-
-
0028880026
-
The role of the calpain-calpastatin system in thyrotropin-releasing hormone-induced selective down-regulation of a protein kinase C isozyme, nPKC epsilon, in rat pituitary GH4C1 cells
-
Eto A, Akita Y, Saido TC, Suzuki K and Kawashima S (1995) The role of the calpain-calpastatin system in thyrotropin-releasing hormone-induced selective down-regulation of a protein kinase C isozyme, nPKC epsilon, in rat pituitary GH4C1 cells. J. Biol. Chem. 270: 25115-25120
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25115-25120
-
-
Eto, A.1
Akita, Y.2
Saido, T.C.3
Suzuki, K.4
Kawashima, S.5
-
65
-
-
0034598746
-
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
-
Alizadeh A, Eisen M, Davis R, Ma C, Lossos I, Rosenwald A, Boldrick JC, Sabet H, Tran T, Yu X, Powell JI, Yang L, Marti GE, Moore T, Hudson Jr J, Lu L, Lewis DB, Tibshirani R, Sherlock G, Chan WC, Greiner TC, Weisenburger DD, Armitage JO, Warnke R, Levy R, Wilson WH, Greyer MR, Byrd JC, Botstein D, Brown PO and Staudt LM (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403: 503-511
-
(2000)
Nature
, vol.403
, pp. 503-511
-
-
Alizadeh, A.1
Eisen, M.2
Davis, R.3
Ma, C.4
Lossos, I.5
Rosenwald, A.6
Boldrick, J.C.7
Sabet, H.8
Tran, T.9
Yu, X.10
Powell, J.I.11
Yang, L.12
Marti, G.E.13
Moore, T.14
Hudson Jr., J.15
Lu, L.16
Lewis, D.B.17
Tibshirani, R.18
Sherlock, G.19
Chan, W.C.20
Greiner, T.C.21
Weisenburger, D.D.22
Armitage, J.O.23
Warnke, R.24
Levy, R.25
Wilson, W.H.26
Greyer, M.R.27
Byrd, J.C.28
Botstein, D.29
Brown, P.O.30
Staudt, L.M.31
more..
-
66
-
-
0037069929
-
Chemotherapy: Targeting the mitochondrial cell death pathway
-
Debatin KM, Poncet D and Kroemer G (2002) Chemotherapy: targeting the mitochondrial cell death pathway. Oncogene 21: 8786-8803
-
(2002)
Oncogene
, vol.21
, pp. 8786-8803
-
-
Debatin, K.M.1
Poncet, D.2
Kroemer, G.3
-
67
-
-
0035324928
-
Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells
-
Hinz M, Loser P, Mathas S, Krappmann D, Dorken B and Scheidereit C (2001) Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells. Blood 97: 2798-2807
-
(2001)
Blood
, vol.97
, pp. 2798-2807
-
-
Hinz, M.1
Loser, P.2
Mathas, S.3
Krappmann, D.4
Dorken, B.5
Scheidereit, C.6
-
68
-
-
0027282044
-
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
-
Boise L, Gonzalez-Garcia M, Postema C, Ding L, Lindsten T, Turka L, Mao X, Nunez G and Thompson C (1993) bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74: 597-608
-
(1993)
Cell
, vol.74
, pp. 597-608
-
-
Boise, L.1
Gonzalez-Garcia, M.2
Postema, C.3
Ding, L.4
Lindsten, T.5
Turka, L.6
Mao, X.7
Nunez, G.8
Thompson, C.9
-
69
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
70
-
-
0033595636
-
The PEST domain of IkBa is necessary and sufficient for in vitro degradation by μ-calpain
-
Shumway SD, Maki M and Miyamoto S (1999) The PEST domain of IkBa is necessary and sufficient for in vitro degradation by μ-calpain. J. Biol. Chem. 274: 30874-30881
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30874-30881
-
-
Shumway, S.D.1
Maki, M.2
Miyamoto, S.3
|