A day in the life of the Bcl-2 protein: Does the turnover rate of Bcl-2 serve as a biological clock for cellular lifespan regulation?

Leukemia Research

Volumn 20, Issue 2, 1996, Pages 109-111

  Reed, J C ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ONCOPROTEIN; PROTEIN BCL 2;

BIOLOGICAL RHYTHM; CELL DEATH; CELL STRAIN HL 60; CELL SURVIVAL; HUMAN; HUMAN CELL; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; PROTEIN METABOLISM; SHORT SURVEY;

EID: 0029932478     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/0145-2126(95)00135-2     Document Type: Note

References (24)

1. Y. Tsujimoto J. Cossman E. Jaffe C. Croce Involvement of the BCL-2 gene in human follicular lymphoma Science 228 1985 1440
2. D.L. Vaux S. Cory J.M. Adams BCL-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells Nature 335 1988 440
3. J.C. Reed Bcl-2 and the regulation of programmed cell death J. Cell Biol. 124 1994 1
4. J.C. Reed Bcl-2: prevention of apoptosis as a mechanism of drug resistance Hematol. Oncol. Clin. N. Am. 9 1995 451
5. D. Delia A. Aiello D. Soligo E. Fontanella C. Melani F. Pezzella M.A. Pierotti G.D. Porta BCL-2 proto-oncogene expression in normal and neoplastic human myeloid cells Blood 79 1992 1291
6. D.M. Hockenbery M. Zutter W. Hickey M. Nahm S.J. Korsmeyer Bcl-2 protein is topographically restricted in tissues characterized by apoptotic cell death Proc. natn. Acad. Sci. USA 88 1991 6961
7. L. Campos J.-P. Roualult O. Sabido N. Roubi C. Vasselon E. Archimbaud J.-P. Magaud D. Guyotat High expression of Bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy Blood 81 1993 3091
8. M. Hanada D. Delia A. Aiello E. Stadtmauer J.C. Reed BCL-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia Blood 82 1993 1820
9. D. Campana E. Coustan-Smith A. Manabe M. Buschle S.C. Raimondi F.G. Behm R. Ashmun M. Aricó A. Biondi C.-H. Pui Prolonged survival of B-lineage acute lymphoblastic leukemia cells is accompanied by overexpression of Bcl-2 protein Blood 81 1993 1025
10. J. Reed C. Stein S. Haldar C. Subasinghe C. Croce S. Yum J. Cohen Antisense-mediated inhibition of BCL-2 proto-oncogene expression and leukemic cell growth: Comparisons of phosphodiester and phosphorothioate oligodeoxynucleotides Cancer Res. 50 1990 6565
11. J. Reed S. Haldar M. Cuddy C. Croce D. Makover Bcl-2-mediated tumorigenicity in a T-lymphoid cell line: synergy with C-MYC and inhibition by BCL-2 antisense Proc. natn. Acad. Sci. USA 87 1990 3660
12. S. Kitada T. Miyashita S. Tanaka J.C. Reed Investigations of antisense oligonucleotides targeted against BCL-2 RNAs Antisense Res. Dev. 3 1993 157
13. S. Kitada S. Takayama K. DeRiel S. Tanaka J.C. Reed Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of BCL-2 gene expression Antisense Res. Dev. 4 1994 71
14. L. Campos O. Sabido J.-P. Rouault D. Guyotat Effects of BCL-2 antisense oligodeoxynucleotides on in vitro proliferation and survival of normal marrow progenitors and leukemic cells Blood 84 1994 595
15. M.V. Blagosklonny M. Alvarez A. Fojo L.M. Neckers Bcl-2 protein downregulation is not required for differentiation of multidrug resistant HL60 cells Leukemia Res. 20 1995 101
16. J.C. Reed Y. Tsujimoto J.D. Alpers C.M. Croce P.C. Nowell Regulation of BCL-2 proto-oncogene expression during normal human lymphocyte proliferation Science 236 1987 1295
17. T. Miyashita S. Krajewski M. Krajewska H.G. Wang H.K. Lin B. Hoffman D. Lieberman J.C. Reed Tumor suppressor p53 is a regulator of bcl-2 and bax in gene expression in vitro and in vivo Oncogene 9 1994 1799
18. D. Delia A. Aiello F. Formelli E. Fontanella A. Costa T. Miyashita J.C. Reed M.A. Pierott Regulation of apoptosis induced by the retinoid N-(4-hydroxyphenyl) retinamide and effect of deregulated Bcl-2 Blood 85 1995 59
19. E. Cuende J.E. Alés-Martinez L. Ding M. Gónzalez-Garcia A. Martinez G. Nunez Programmed cell death by Bcl-2-dependent and independent mechanisms in B lymphoma cells EMBO J. 12 1993 1555
20. T. Sato M. Hanada S. Bodrug S. Irie N. Iwama L.H. Boise C.B. Thompson E. Golemis L. Fong H.-G. Wang J.C. Reed Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system Proc. natn. Acad. Sci. USA 91 1994 9238
21. S. Takayama T. Sato S. Krajewski K. Kochel S. Irie J.A. Millan J.C. Reed Cloning and functional analysis of BAG-1: a novel Bcl-2 binding protein with anti-cell death activity Cell 80 1995 279
22. J.M. Boyd S. Malstrom T. Subramanian L.K. Venkatesch U. Schaeper B. Elangovan C. D'Sa-Epper G. Chinnadurai Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins Cell 79 1993 341
23. K.M. Kozopas T. Yang H.L. Buchan P. Zhou R. Craig Mcl-1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL-2 Proc. natn. Acad. Sci. USA 90 1993 3516
24. S. Haldar N. Jena C.M. Croce Inactivation of BCL-2 by phosphorylation Proc. natn. Acad. Sci. USA 92 1995 4507