NH2-terminal BH4 domain of Bcl-2 is functional for heterodimerization with Bax and inhibition of apoptosis

Journal of Biological Chemistry

Volumn 274, Issue 29, 1999, Pages 20415-20420

  Hirotani, Miki ^a   Zhang, Yongke ^a,c   Fujita, Naoya ^a   Naito, Mikihiko ^a   Tsuruo, Takashi ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b CANCER CHEMOTHERAPY CENTER   (Japan)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; INTERLEUKIN 2; PROTEIN BAX; PROTEIN BCL 2; PROTEINASE; STAUROSPORINE; BAX PROTEIN, HUMAN; BAX PROTEIN, MOUSE; CASPASE; ONCOPROTEIN;

APOPTOSIS; ARTICLE; CANCER THERAPY; CELL CULTURE; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVITY; GENETIC TRANSFECTION; PRIORITY JOURNAL; PROTEIN DOMAIN; REGULATORY MECHANISM; SITE DIRECTED MUTAGENESIS; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; ENZYME ACTIVATION; GENETICS; HUMAN; HYDROLYSIS; METABOLISM; MOLECULAR GENETICS; MOUSE; PROTEIN BINDING; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELL LINE; DIMERIZATION; ENZYME ACTIVATION; HUMANS; HYDROLYSIS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0033575142     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.29.20415     Document Type: Article

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