Xenomitochondrial embryonic stem cells and mice: Modeling human mitochondrial biology and disease

Gene Therapy and Regulation

Volumn 2, Issue 4, 2004, Pages 283-300

  Cannon, Matthew V ^a   Pinkert, Carl A ^a   Trounce, Ian A ^b  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Embryonic stem cells; Gene transfer; Genetic engineering; Heteroplasmy; Mitochondria; Rhodamine 6G; Transgenic animals

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; MITOCHONDRIAL DNA; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; RHODAMINE 6G;

APOPTOSIS; CELL DIVISION; CELL LINEAGE; CYBRID; DISEASE MODEL; DNA MODIFICATION; DNA SEQUENCE; EMBRYONIC STEM CELL; ENZYME INHIBITION; GENE AMPLIFICATION; GENE MUTATION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GENETIC ENGINEERING; HETEROPLASMY; HYBRID CELL; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT GENE; MEMBRANE POTENTIAL; MITOCHONDRIAL DNA DISORDER; MITOCHONDRIAL GENETICS; MITOCHONDRIAL MEMBRANE; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; RESPIRATORY CHAIN; REVIEW;

ANIMALIA;

EID: 21344467946     PISSN: 13889532     EISSN: None     Source Type: Journal    
DOI: 10.1163/1568558043967454     Document Type: Review

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