메뉴 건너뛰기




Volumn 28, Issue 3, 2003, Pages 138-141

Antimicrobial peptides - Their role in immunity and therapeutic potential

Author keywords

Antimicrobial peptides; Immunity

Indexed keywords

ALPHA DEFENSIN; ANTIINFECTIVE AGENT; BACTERIUM LIPOPOLYSACCHARIDE; BETA DEFENSIN; CAP 18; CATHELICIDIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CATHELIN; CATHELIN RELATED ANTIMICROBIAL PEPTIDE; CATHEPSIN G; CEPHALOSPORIN DERIVATIVE; COLISTIN; CYCLOSPORIN; CYSTEINE; DEFENSIN; DEFENSIN 1; DEFENSIN 2; DEFENSIN 3; HISTAMINE; HUMAN NEUTROPHIL PEPTIDE 4; INTERLEUKIN 1; LACTOFERRIN; LYSOZYME; MAGAININ DERIVATIVE; MESSENGER RNA; NEOMYCIN; OFLOXACIN; PENICILLIN DERIVATIVE; PEPTIDE DERIVATIVE; PEPTIDE SYNTHASE; PEXIGANAN; PMAP 23; POLYMYXIN B; POLYPEPTIDE ANTIBIOTIC AGENT; PR 39; PROTEGRIN; RL 37; SMAP 29; SMAP 34; SOMATOMEDIN C; TRIPEPTIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 20444504350     PISSN: 14263912     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (2)

References (54)
  • 1
    • 0037165196 scopus 로고    scopus 로고
    • Antimicrobial peptides of multicellular organisms
    • Zasloff M (2002): Antimicrobial peptides of multicellular organisms. Nature 415 (6870): 389-395.
    • (2002) Nature , vol.415 , Issue.6870 , pp. 389-395
    • Zasloff, M.1
  • 2
    • 0032826448 scopus 로고    scopus 로고
    • Polymyxin B sulfate and colistin: Old antibiotics for emerging multiresistant gram-negative bacteria
    • Evans ME, Feola DJ, Rapp RP (1999): Polymyxin B sulfate and colistin: old antibiotics for emerging multiresistant gram- negative bacteria. Ann Pharmacother 33 (9): 960-967.
    • (1999) Ann Pharmacother , vol.33 , Issue.9 , pp. 960-967
    • Evans, M.E.1    Feola, D.J.2    Rapp, R.P.3
  • 4
    • 0031039956 scopus 로고    scopus 로고
    • Peptide antibiotics
    • Hancock RE (1997): Peptide antibiotics. Lancet 349 (9049): 418-422.
    • (1997) Lancet , vol.349 , Issue.9049 , pp. 418-422
    • Hancock, R.E.1
  • 5
    • 0037005996 scopus 로고    scopus 로고
    • Current status of defensins and their role in innate and adoptive immunity
    • Raj PA, Dentino AR (2002): Current status of defensins and their role in innate and adoptive immunity. FEMS Microbiol Lett 206: 9-18.
    • (2002) FEMS Microbiol Lett , vol.206 , pp. 9-18
    • Raj, P.A.1    Dentino, A.R.2
  • 6
    • 0022402545 scopus 로고
    • Defensins: Natural peptide antibiotics of human neutrophils
    • Ganz T, Selsted ME, Szklarek D, et al. (1985): Defensins: natural peptide antibiotics of human neutrophils. J Clin Invest 76 (4): 1427-1435.
    • (1985) J Clin Invest , vol.76 , Issue.4 , pp. 1427-1435
    • Ganz, T.1    Selsted, M.E.2    Szklarek, D.3
  • 7
    • 0022395334 scopus 로고
    • Primary structures of three human neutrophil defensins
    • Selsted ME, Harwig SS, Ganz T, et al. (1985): Primary structures of three human neutrophil defensins. J Clin Invest 76 (4): 1436-1439.
    • (1985) J Clin Invest , vol.76 , Issue.4 , pp. 1436-1439
    • Selsted, M.E.1    Harwig, S.S.2    Ganz, T.3
  • 8
    • 0026660392 scopus 로고
    • Enteric defensins: Antibiotic peptide components of intestinal host defense
    • Selsted ME, Miller SI, Menschen AH, Ouellette AJ (1992): Enteric defensins: antibiotic peptide components of intestinal host defense. J Cell Biol 118: 929-936.
    • (1992) J Cell Biol , vol.118 , pp. 929-936
    • Selsted, M.E.1    Miller, S.I.2    Menschen, A.H.3    Ouellette, A.J.4
  • 9
    • 0031898688 scopus 로고    scopus 로고
    • Gene expression, immunolocalization and secretion of human defensin 5 in human female reproductive tract
    • Quayle AJ, Porter EM, Nussbaum AA, et al. (1998): Gene expression, immunolocalization and secretion of human defensin 5 in human female reproductive tract. Am J Pathol 152: 1247-1258.
    • (1998) Am J Pathol , vol.152 , pp. 1247-1258
    • Quayle, A.J.1    Porter, E.M.2    Nussbaum, A.A.3
  • 10
    • 0035128862 scopus 로고    scopus 로고
    • Human defensin 5 is stored in precursor form in normal Paneth cells and is expressed by some villous epithelial cells and by metaplastic Paneth cells in the colon in inflammatory bowel disease
    • Cunliffe RN, Rose FR, Keyte J, et al. (2001): Human defensin 5 is stored in precursor form in normal Paneth cells and is expressed by some villous epithelial cells and by metaplastic Paneth cells in the colon in inflammatory bowel disease. Gut 48: 176-185.
    • (2001) Gut , vol.48 , pp. 176-185
    • Cunliffe, R.N.1    Rose, F.R.2    Keyte, J.3
  • 11
    • 0036172988 scopus 로고    scopus 로고
    • Elevated levels of α-defensins in plasma and BAL fluid of patients with active pulmonary tuberculosis
    • Ashitani J, Mukae H, Hiratsuka T, et al. (2002): Elevated levels of α-defensins in plasma and BAL fluid of patients with active pulmonary tuberculosis. CHEST 121 (2): 519-526.
    • (2002) CHEST , vol.121 , Issue.2 , pp. 519-526
    • Ashitani, J.1    Mukae, H.2    Hiratsuka, T.3
  • 12
    • 0036141449 scopus 로고    scopus 로고
    • Plasma concentrations of defensins and lactoferrin in children with severe sepsis
    • Thomas NJ, Carcillo JA, Doughty LA, et al. (2002): Plasma concentrations of defensins and lactoferrin in children with severe sepsis. Pediatr Infct Dis J 21 (1): 34-38.
    • (2002) Pediatr Infct Dis J , vol.21 , Issue.1 , pp. 34-38
    • Thomas, N.J.1    Carcillo, J.A.2    Doughty, L.A.3
  • 13
    • 0025811874 scopus 로고
    • Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: Peptide isolation and cloning of cDNA
    • Diamond G, Zasloff M, Eck H, et al. (1991): Tracheal antimicrobial peptide, a cysteine- rich peptide from mammalian tracheal mucosa: peptide isolation and cloning of cDNA. Proc Natl Acad Sci USA 88: 3952-3956.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3952-3956
    • Diamond, G.1    Zasloff, M.2    Eck, H.3
  • 14
    • 0028981702 scopus 로고
    • hBD-1: A novel β-defensin from human plasma
    • Bensch K, Raida M, Magert HJ, et al. (1995): hBD-1: a novel β-defensin from human plasma. FEBS Lett 368: 331-335.
    • (1995) FEBS Lett , vol.368 , pp. 331-335
    • Bensch, K.1    Raida, M.2    Magert, H.J.3
  • 15
    • 0031093274 scopus 로고    scopus 로고
    • Human airway epithelia express a beta-defensin
    • McCray JP, Bentley L (1997): Human airway epithelia express a beta-defensin. Am J Respir Cell Mol Biol 16 (3): 343-349.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , Issue.3 , pp. 343-349
    • McCray, J.P.1    Bentley, L.2
  • 16
    • 0032523214 scopus 로고    scopus 로고
    • Human beta-defensin-1: An antimicrobial peptide of urogenital tissues
    • Valore EV, Park CH, Quayale AJ, et al. (1998): Human beta-defensin-1: an antimicrobial peptide of urogenital tissues. J Clin Invest 101 (8): 1633-1642.
    • (1998) J Clin Invest , vol.101 , Issue.8 , pp. 1633-1642
    • Valore, E.V.1    Park, C.H.2    Quayale, A.J.3
  • 17
    • 0031581544 scopus 로고    scopus 로고
    • Expression of natural peptide antibiotics in human skin
    • Fulton C, Anderson GM, Zasloff M, et al. (1997): Expression of natural peptide antibiotics in human skin. The Lancet 350: 1750-1751.
    • (1997) The Lancet , vol.350 , pp. 1750-1751
    • Fulton, C.1    Anderson, G.M.2    Zasloff, M.3
  • 18
    • 0034946112 scopus 로고    scopus 로고
    • Expression of the peptide antibiotics human β defensin-1 and human β defensin-2 in normal human skin
    • Ali RS, Falconer A, Ikram M, et al. (2001): Expression of the peptide antibiotics human β defensin-1 and human β defensin-2 in normal human skin. J Invest Dermatol 117: 106-111.
    • (2001) J Invest Dermatol , vol.117 , pp. 106-111
    • Ali, R.S.1    Falconer, A.2    Ikram, M.3
  • 20
    • 0036178642 scopus 로고    scopus 로고
    • Human β defensin-2 production in keratinocytes is regulated by IL1, bacteria, and the state of differentiation
    • Liu AY, Destoumieux D, Wong AV, et al. (2002): Human β defensin-2 production in keratinocytes is regulated by IL1, bacteria, and the state of differentiation. J Invest Dermatol 118: 275-281.
    • (2002) J Invest Dermatol , vol.118 , pp. 275-281
    • Liu, A.Y.1    Destoumieux, D.2    Wong, A.V.3
  • 21
    • 0037250369 scopus 로고    scopus 로고
    • Keratinocyte expression of human β defensin 2 following bacterial infection: Role in cutaneous host defence
    • Dinulos JGH, Mentele L, Fredericks LP, et al. (2003): Keratinocyte expression of human β defensin 2 following bacterial infection: role in cutaneous host defence. Clin Diagnost Lab Immunol 10 (1): 161-166.
    • (2003) Clin Diagnost Lab Immunol , vol.10 , Issue.1 , pp. 161-166
    • Dinulos, J.G.H.1    Mentele, L.2    Fredericks, L.P.3
  • 22
    • 0037218616 scopus 로고    scopus 로고
    • By IL1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide
    • Liu L, Roberts AA, Ganz T (2002): By IL1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide. J Immunol 170: 575-580.
    • (2002) J Immunol , vol.170 , pp. 575-580
    • Liu, L.1    Roberts, A.A.2    Ganz, T.3
  • 23
    • 0035937107 scopus 로고    scopus 로고
    • Isolation and characterization of human β defensin-3, a novel human inducible peptide antibiotic
    • Harder J, Bartels J, Christophers E, Schroeder JM (2001): Isolation and characterization of human β defensin-3, a novel human inducible peptide antibiotic. J Biol Chem 276 (8): 5707-5713.
    • (2001) J Biol Chem , vol.276 , Issue.8 , pp. 5707-5713
    • Harder, J.1    Bartels, J.2    Christophers, E.3    Schroeder, J.M.4
  • 24
    • 0035430147 scopus 로고    scopus 로고
    • Human β defensin-4: A novel inducible peptide with a specific salt-sensitive spectrum of antimocrobial activity
    • Garcia JR, Krause A, Schulz S, et al. (2001): Human β defensin-4: a novel inducible peptide with a specific salt-sensitive spectrum of antimocrobial activity. FASEB J 15 (10): 1819-1821.
    • (2001) FASEB J , vol.15 , Issue.10 , pp. 1819-1821
    • Garcia, J.R.1    Krause, A.2    Schulz, S.3
  • 25
    • 0037133295 scopus 로고    scopus 로고
    • Discovery of five conserved beta defensin gene clusters using a computational search strategy
    • Schutte BC, Mitros JP, Bartllet JA, et al. (2002): Discovery of five conserved beta defensin gene clusters using a computational search strategy. Proc Natl Acad Sci USA 99 (4): 2129-2133.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.4 , pp. 2129-2133
    • Schutte, B.C.1    Mitros, J.P.2    Bartllet, J.A.3
  • 26
    • 0036040263 scopus 로고    scopus 로고
    • Expression of β defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells
    • Duits LA, Ravensbergen B, Rademaker M, et al. (2002): Expression of β defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells. Immunol 106: 517-525.
    • (2002) Immunol , vol.106 , pp. 517-525
    • Duits, L.A.1    Ravensbergen, B.2    Rademaker, M.3
  • 27
    • 0033569410 scopus 로고    scopus 로고
    • A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha defensins
    • Tang YQ, Yaun J, Osapay G, et al. (1999): A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha defensins. Science 286: 498-502.
    • (1999) Science , vol.286 , pp. 498-502
    • Tang, Y.Q.1    Yaun, J.2    Osapay, G.3
  • 28
    • 0028844134 scopus 로고
    • Cathelicidins: A novel protein family with a common proregion and a variable C-terminal antimicrobial domain
    • Zanetti M, Gennaro R, Romeo D (1995): Cathelicidins: a novel protein family with a common proregion and a variable C-terminal antimicrobial domain. FEBS Lett 374: 1-5.
    • (1995) FEBS Lett , vol.374 , pp. 1-5
    • Zanetti, M.1    Gennaro, R.2    Romeo, D.3
  • 29
    • 0036379140 scopus 로고    scopus 로고
    • Cathelicidins, essential gene - Encoded mammalian antibiotics
    • Zaiou M, Gallo RL (2002): Cathelicidins, essential gene - encoded mammalian antibiotics. J Mol Med 80: 549-561.
    • (2002) J Mol Med , vol.80 , pp. 549-561
    • Zaiou, M.1    Gallo, R.L.2
  • 30
    • 0030880531 scopus 로고    scopus 로고
    • The human antibacterial cathelicidin, hCAP-18, is synthesized in myelocytes and metamyelocytes and localized to specific granules in neutrophils
    • Sorensen O, Arnljots K, Cowland JB, et al. (1997): The human antibacterial cathelicidin, hCAP-18, is synthesized in myelocytes and metamyelocytes and localized to specific granules in neutrophils. Blood 90: 2796-2803.
    • (1997) Blood , vol.90 , pp. 2796-2803
    • Sorensen, O.1    Arnljots, K.2    Cowland, J.B.3
  • 31
    • 0034332193 scopus 로고    scopus 로고
    • The human antimicrobial and chemotactic peptides LL37 and α defensins are expressed by specific lymphocytes and monocytes populations
    • Agerberth B, Charo J, Werr J, et al. (2000): The human antimicrobial and chemotactic peptides LL37 and α defensins are expressed by specific lymphocytes and monocytes populations. Blood 96: 3086-3093.
    • (2000) Blood , vol.96 , pp. 3086-3093
    • Agerberth, B.1    Charo, J.2    Werr, J.3
  • 32
    • 0032482980 scopus 로고    scopus 로고
    • The peptide antibiotic LL37/hCAP18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface
    • Bals R, Wang X, Zasloff M, Wilson JM (1998): The peptide antibiotic LL37/hCAP18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface. Proc Natl Acad Sci USA 95: 9541-9546.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9541-9546
    • Bals, R.1    Wang, X.2    Zasloff, M.3    Wilson, J.M.4
  • 33
    • 0032903987 scopus 로고    scopus 로고
    • The human cationic antimicrobial protein (hCAP18), a peptide antibiotic, is widely expressed in human squamous epithelia and colocalizes with IL6
    • Frohm Nilsson M, Sandstedt B, Sorensen O, et al. (1999): The human cationic antimicrobial protein (hCAP18), a peptide antibiotic, is widely expressed in human squamous epithelia and colocalizes with IL6. Infect Immunol 67: 2561-2566.
    • (1999) Infect Immunol , vol.67 , pp. 2561-2566
    • Frohm Nilsson, M.1    Sandstedt, B.2    Sorensen, O.3
  • 34
    • 0036151109 scopus 로고    scopus 로고
    • Cell differntiation is a key determinant of cathelicidin LL37/human cationic antimicrobial protein 18 expression by human colon epithelium
    • Hase K, Eckmann L, Leopard JD, et al. (2002): Cell differntiation is a key determinant of cathelicidin LL37/human cationic antimicrobial protein 18 expression by human colon epithelium. Infect Immun 70 (2): 953-963.
    • (2002) Infect Immun , vol.70 , Issue.2 , pp. 953-963
    • Hase, K.1    Eckmann, L.2    Leopard, J.D.3
  • 35
    • 0030956070 scopus 로고    scopus 로고
    • The expression of the gene coding for the antibacterial peptide LL37 is induced in human keratinocytes during inflammatory disorders
    • Frohm M., Agerberth B, Ahangari G, et al. (1997): The expression of the gene coding for the antibacterial peptide LL37 is induced in human keratinocytes during inflammatory disorders. J Biol Chem 272 (24): 15258-15263.
    • (1997) J Biol Chem , vol.272 , Issue.24 , pp. 15258-15263
    • Frohm, M.1    Agerberth, B.2    Ahangari, G.3
  • 36
    • 0037057645 scopus 로고    scopus 로고
    • Endogenous antimicrobial peptides and skin infections in atopic dermatitis
    • Ong PY, Ohtake T, Brandt C, et al. (2002): Endogenous antimicrobial peptides and skin infections in atopic dermatitis. Nengl J Med 347 (15): 1151-1160.
    • (2002) Nengl J Med , vol.347 , Issue.15 , pp. 1151-1160
    • Ong, P.Y.1    Ohtake, T.2    Brandt, C.3
  • 37
    • 0034946907 scopus 로고    scopus 로고
    • Cutaneous injury induces the release of cathelicidin antimicrobial peptides active against group A Streptococcus
    • Dorschner RA, Pestonjamasp VK, Tamakuwala S, et al. (2001): Cutaneous injury induces the release of cathelicidin antimicrobial peptides active against group A Streptococcus. J Invest Dermatol 117: 91-97.
    • (2001) J Invest Dermatol , vol.117 , pp. 91-97
    • Dorschner, R.A.1    Pestonjamasp, V.K.2    Tamakuwala, S.3
  • 38
    • 0038189571 scopus 로고    scopus 로고
    • Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors
    • Sorensen OE, Cowland JB, Theilgaard-Monch K, et al. (2003): Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors. J Immunol 170: 5583-5589.
    • (2003) J Immunol , vol.170 , pp. 5583-5589
    • Sorensen, O.E.1    Cowland, J.B.2    Theilgaard-Monch, K.3
  • 39
    • 0033529627 scopus 로고    scopus 로고
    • The human antibacterial cathelicidin, hCAP18, is bound to lipoproteins in plasma
    • Sorensen O, Bratt T, Johnsen AH, et al. (1999): The human antibacterial cathelicidin, hCAP18, is bound to lipoproteins in plasma. J Biol Chem 274: 22445-22451.
    • (1999) J Biol Chem , vol.274 , pp. 22445-22451
    • Sorensen, O.1    Bratt, T.2    Johnsen, A.H.3
  • 40
    • 0031009432 scopus 로고    scopus 로고
    • Identification of CRAMP, a cathelin related antimicrobial peptide expressed in the embryonic and adult mouse
    • Gallo RL, Kim KJ, Bernfield M, et al. (1997): Identification of CRAMP, a cathelin related antimicrobial peptide expressed in the embryonic and adult mouse. J Biol Chem 272: 13088-13093.
    • (1997) J Biol Chem , vol.272 , pp. 13088-13093
    • Gallo, R.L.1    Kim, K.J.2    Bernfield, M.3
  • 41
    • 0035936156 scopus 로고    scopus 로고
    • Innate abtimicrobial peptide protects the skin from invasive bacterial infection
    • Nizet V, Ohtake T, Lauth X, et al. (2001): Innate abtimicrobial peptide protects the skin from invasive bacterial infection. Nature 414: 454-457.
    • (2001) Nature , vol.414 , pp. 454-457
    • Nizet, V.1    Ohtake, T.2    Lauth, X.3
  • 42
    • 0037383501 scopus 로고    scopus 로고
    • Neonatal skin in mice and humans expresses increased levels of antimicrobial peptides: Innate immunity during development of the adaptive response
    • Dorschner RA, Lin KH, Murakami M, Gallo RL (2003): Neonatal skin in mice and humans expresses increased levels of antimicrobial peptides: innate immunity during development of the adaptive response. Pediatr Res 53 (4): 566-572.
    • (2003) Pediatr Res , vol.53 , Issue.4 , pp. 566-572
    • Dorschner, R.A.1    Lin, K.H.2    Murakami, M.3    Gallo, R.L.4
  • 43
    • 0035143050 scopus 로고    scopus 로고
    • Abundant human beta defensin 1 expression in milk and mammary gland epithelium
    • Jia HP, Stamer T, Ackermann M, et al. (2001): Abundant human beta defensin 1 expression in milk and mammary gland epithelium. J Pediatr 138: 109-112.
    • (2001) J Pediatr , vol.138 , pp. 109-112
    • Jia, H.P.1    Stamer, T.2    Ackermann, M.3
  • 44
    • 0033566011 scopus 로고    scopus 로고
    • Neutrophil defensins induce histamine secretion from mast cells: Mechanisms of action
    • Befus AD, Mowat C, Gilchrist M, et al. (1999): Neutrophil defensins induce histamine secretion from mast cells: mechanisms of action. J Immunol 163: 947-953.
    • (1999) J Immunol , vol.163 , pp. 947-953
    • Befus, A.D.1    Mowat, C.2    Gilchrist, M.3
  • 45
    • 0035058454 scopus 로고    scopus 로고
    • Evolution of the effect of peptide antibiotics human beta defensin 2 and LL37 on histamine release and prostaglandin D2 production from mast cells
    • Niyonsaba F, Someya A, Hirata M, et al. (2001): Evolution of the effect of peptide antibiotics human beta defensin 2 and LL37 on histamine release and prostaglandin D2 production from mast cells. Eur J Immunol 31: 1066-1075.
    • (2001) Eur J Immunol , vol.31 , pp. 1066-1075
    • Niyonsaba, F.1    Someya, A.2    Hirata, M.3
  • 46
    • 0024797674 scopus 로고
    • Monocyte-chemotactic activity of defensins from human neutrophils
    • Territo MC, Ganz T, Selsted ME, Lehler R (1989): Monocyte-chemotactic activity of defensins from human neutrophils. J Clin Invest 84: 2017-2020.
    • (1989) J Clin Invest , vol.84 , pp. 2017-2020
    • Territo, M.C.1    Ganz, T.2    Selsted, M.E.3    Lehler, R.4
  • 47
    • 0033569408 scopus 로고    scopus 로고
    • β defensins: Linking innate and adaptive immunity through dendritic and T cell CCR6
    • Yang D, Chertov O, Bykovskaia SN, et al. (1999): β defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science 286: 525-528.
    • (1999) Science , vol.286 , pp. 525-528
    • Yang, D.1    Chertov, O.2    Bykovskaia, S.N.3
  • 48
    • 0033844287 scopus 로고    scopus 로고
    • Human neutrophil defensins selectively chemoattract naive and immature dendritic cells
    • Yang D, Chen Q, Chertov O, et al. (2000): Human neutrophil defensins selectively chemoattract naive and immature dendritic cells. J Lukocyte Biol 68: 9-14.
    • (2000) J Lukocyte Biol , vol.68 , pp. 9-14
    • Yang, D.1    Chen, Q.2    Chertov, O.3
  • 49
    • 0036829687 scopus 로고    scopus 로고
    • Toll-like receptor 4-dependent activation of dendritic cells by β defensin 2
    • Biragyn A, Ruffini PA, Leiter CA, et al. (2002): Toll-like receptor 4-dependent activation of dendritic cells by β defensin 2. Science 298: 1025-1029.
    • (2002) Science , vol.298 , pp. 1025-1029
    • Biragyn, A.1    Ruffini, P.A.2    Leiter, C.A.3
  • 50
    • 0029892845 scopus 로고    scopus 로고
    • Defensin modulates tissue-type plasminogen activator and plasminogen binding to fibrin and endothelial cells
    • Higazi A, Ganz T, Kariko K, Cines DB (1996): Defensin modulates tissue-type plasminogen activator and plasminogen binding to fibrin and endothelial cells. J Biol Chem 271 (30): 17650-17655.
    • (1996) J Biol Chem , vol.271 , Issue.30 , pp. 17650-17655
    • Higazi, A.1    Ganz, T.2    Kariko, K.3    Cines, D.B.4
  • 51
    • 0037335205 scopus 로고    scopus 로고
    • The cathelicidin anti-microbial peptide LL37 is involved in re-epithelialization of human skin wound and its lacking in chronic ulcer epithelium
    • Heilborn JD, Frohm Nilsson M, Kratz G, et al. (2003): The cathelicidin anti-microbial peptide LL37 is involved in re-epithelialization of human skin wound and its lacking in chronic ulcer epithelium. J Invest Dermatol 120: 379-389.
    • (2003) J Invest Dermatol , vol.120 , pp. 379-389
    • Heilborn, J.D.1    Frohm Nilsson, M.2    Kratz, G.3
  • 52
    • 0028721118 scopus 로고
    • Potential therapeutic applications of magainins and other antimicrobial agents of animal origin
    • Jacob L, Zasloff M (1994): Potential therapeutic applications of magainins and other antimicrobial agents of animal origin. Ciba Found Symp 186: 197-216.
    • (1994) Ciba Found Symp , vol.186 , pp. 197-216
    • Jacob, L.1    Zasloff, M.2
  • 53
    • 0033948397 scopus 로고    scopus 로고
    • IB-367, a protegrin peptide with in vitro and in vivo activities against the microflora associated with oral mucositis
    • Mosca DA, Hurst MA, SO W, et al. (2000): IB-367, a protegrin peptide with in vitro and in vivo activities against the microflora associated with oral mucositis. Antimicrob Agents Chemother 44: 1803-1808.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 1803-1808
    • Mosca, D.A.1    Hurst, M.A.2
  • 54
    • 0033858613 scopus 로고    scopus 로고
    • Development of protegrins for the treatment and prevention of oral mucositis: Structure-activity relationships of synthetic protegrin analogues
    • Chen J, Falla TJ, Liu H, et al. (2000): Development of protegrins for the treatment and prevention of oral mucositis: structure-activity relationships of synthetic protegrin analogues. Biopolymers 55: 88-98.
    • (2000) Biopolymers , vol.55 , pp. 88-98
    • Chen, J.1    Falla, T.J.2    Liu, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.