Defensin modulates tissue-type plasminogen activator and plasminogen binding to fibrin and endothelial cells

Journal of Biological Chemistry

Volumn 271, Issue 30, 1996, Pages 17650-17655

  Higazi, Abd Al Roof ^a,c   Ganz, Tomas ^b   Kariko, Katalyn ^a   Cines, Douglas B ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEFENSIN; FIBRIN; PLASMINOGEN; PLASMINOGEN[GLUTAMIC ACID]; PLASMINOGEN[LYSINE]; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; FIBRINOLYSIS; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; UMBILICAL VEIN;

ANTI-INFECTIVE AGENTS; BLOOD PROTEINS; DEFENSINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; FIBRIN; HUMANS; LEUKOCYTES; PLASMINOGEN; PROTEIN BINDING; TISSUE PLASMINOGEN ACTIVATOR;

EID: 0029892845     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.30.17650     Document Type: Article

References (39)

1. Ganz, T., Selated, M. E., Szklarek, D., Harwig, S. S. L., Daher, K., Bainton, D. F., and Lehrer, R. I. (1985) J. Clin. Invest. 1427-1435
2. Selsted, M. E., Harwig, S. S. L., Ganz, T., Schilling, J. W., and Lehrer, R. I. (1985) J. Clin. Invest. 76, 1436-1439
3. Kagan, B. L., Ganz, T., and Lehrer, R. I. (1994) Toxicology 87, 131-149
4. Selsted, M. E., and Harwig, S. S. (1989) J. Biol. Chem. 264, 4003-4007
5. Hill, C. F., Yee, J., Delsted, M. E., and Eisenberg, D. (1991) Science 251, 1481-1485
6. Ganz, T. (1987) Infect. Immun. 55, 568-571
7. Jones, D. E., and Bevins, C. L. (1992) J. Biol. Chem. 267, 23216-23225
8. Jones, D. E., and Bevins, C. L. (1993) FEBS Lett. 315, 187-192
9. Bensch, K. W., Raida, M., Magen, H. J., Schulz-Knappe, F., and Forssmann, W. G. (1995) FEES Lett. 368, 331-335
10. Panyutich, A. V., Panyutich, E. A., Krapivin, V. A., Baturevich, E. A., and Ganz, T. (1993) J. Lab. Clin. Med. 122, 202-207
11. Lichtenstein, A., Ganz, T., Selsted, M. E., and Lehrer, R. I. (1986) Blood 1407-1410
12. Okrent, D. G., Lichtenstein, A. K., and Ganz, T. (1990) Am. Rev. Respir. Dis. 141, 179-185
13. Lichtenstein, A. K., Ganz, T., Selsted, M. E., and Lehrer, R. I. (1988) Cell Immunol. 114, 104-116
14. Lichtenstein, A. K., Ganz, T., Nguyen, T.-M., Selsted, M. E., and Lehrer, R. I. (1988) J. Immunol. 140, 2686-2694
15. Panyutich, A., and Ganz, T. (1991) Am. J. Respir. Cell Mol. Biol. 5, 101-106
16. Panyutich, A. V., Szold, O., Poon, P. H., Tseng, Y., and Ganz, T. (1994) FEBS Lett. 356, 169-173
17. Panyutich, A. V., Hiemstra, P. S., van Wetering, S., and Ganz, T. (1995) Am. J. Respir. Cell Mol. Biol. 12, 351-357
18. Higazi, A. A.-R, Barghouti, I.I., and Abu-Much, H. (1995) J. Biol. Chem. 270, 9472-9477
19. Edwards, R. L., and Rickles, F. R. (1978) Science 200, 541-543
20. Marder, V. J., Feinstein, D. I., Francis, C. W., and Colman, R. W. (1994) in Hemostasis and Thrombosis: Basic Principles and Clinical Practice (Colman, R. W., Hirsch, J., Marder, V. J., and Salzman, E. W., eds) pp. 1023-1063, J. B. Lippincott Co., Philadelphia
21. Menkin, V. (1938) Physiol. Rev. 18, 366-392
22. Fless, G. M., Rolih, C. A., and Scanu, A. M. (1984) J. Biol. Chem. 259, 11470-11478
23. Eaton, D. L., Fless, G. M., Kohr, W. J., McLean, J. W., Xu, Q. T., Miller, C. G., Lawn, R. M., and Scanu, A. M. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 3224-3228
24. Deutch, D. G., and Mertz, E. T. (1970) Science 170, 1095-1096
25. Barnathan, E. S., Kuo, A., van der Keyl, H., McCrae, K. R., Larsen, G. R., and Cines, D. B. (1988) J. Biol. Chem. 263, 7792-7799
26. Miles, L. A., Dahlberg, C. M., Plescia, J., Felez, J., Kato, K., and Plow, E. F. (1991) Biochemistry 30, 1682-1691
27. Beebe, D. P., Miles, L. A., and Plow, E. F. (1989) Blood 74, 2034-2037
28. Hajjar, K. A., and Hamel, N. M. 11990) J. Biol. Chem. 265, 2908-2916
29. Hajjar, K. A., Jacovina, A. T., and Checko, J. (1994) J. Biol. Chem. 269, 21191-21197
30. Cesarman, G. M., Guevara, C. A., and Hajjar, K. A. (1994) J Biol. Chem. 269, 21198-21203
31. Harwig, S. S., Ganz, T., and Lehrer, R. I. (1994) Methods Enzymol. 236, 160-172
32. Cines, D. B., Lyss, A. P., Reeber, M. J., Bina, M., and DeHoratius, E. (1984) J. Clin. Invest. 73, 611-625
33. Higazi, A. A.-R., Aziza, R., Samara, A. A., and Mayer, M. (1994) Biochem. J. 300, 251-255
34. Hajjar, K. A., and Nachman, R. L. (1988) J. Clin. Invest. 82, 1769-1778
35. de Vos, A. M., Ultsch, M. H., Kelley, R. F., Padmanabhan, K., Tulinsky, A., Westbrook, M., and Kossiakoff, A. A. (1992) Biochemistry 31, 270-279
36. Liu, J., Harpel, P. C., and Gurewich, V. (1994) Biochemistry 33, 2554-2560
37. Hajjar, K. A., Harpel, P. C., Jaffe, E. A., and Nachman, R. L. (1986) J. Biol. Chem. 261, 11656-11662
38. Hu, C.-K., Kohnert, U., Wilhelm, O., Fischer, S., and Llinas, M. (1994) Biochemistry 33, 11760-11766
39. Grainger, D. J., Kemp, P. R., Liu, A. C., Lawn, R. M., and Metcalfe, J. C. (1994) Nature 370, 460-462