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Volumn 137, Issue 1, 2005, Pages 73-81

Epithelial defence by γδ T cells

Author keywords

T cells; Antimicrobial peptides; Chemokine receptors; Cytokines; Intraepithelial lymphocytes

Indexed keywords

DEFENSIN; ANTIMICROBIAL CATIONIC PEPTIDE; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 19444383661     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000085107     Document Type: Review
Times cited : (59)

References (100)
  • 1
    • 0034091286 scopus 로고    scopus 로고
    • γ/δ cells: A right time and a right place for a conserved third way of protection
    • Hayday AC: γ/δ cells: A right time and a right place for a conserved third way of protection. Annu Rev Immunol 2000;18:975-1026.
    • (2000) Annu Rev Immunol , vol.18 , pp. 975-1026
    • Hayday, A.C.1
  • 2
    • 0033015423 scopus 로고    scopus 로고
    • γ/δ T cells, their T cell receptor usage and role in human diseases
    • Kabelitz D, Wesch D, Hinz T: γ/δ T cells, their T cell receptor usage and role in human diseases. Springer Semin Immunopathol 1999;21:55-75.
    • (1999) Springer Semin Immunopathol , vol.21 , pp. 55-75
    • Kabelitz, D.1    Wesch, D.2    Hinz, T.3
  • 3
    • 0025668510 scopus 로고
    • Genetic organization of the human T-cell receptor gamma and delta loci
    • Lefranc MP, Rabbits TH: Genetic organization of the human T-cell receptor gamma and delta loci. Res Immunol 1990;141:565-577.
    • (1990) Res Immunol , vol.141 , pp. 565-577
    • Lefranc, M.P.1    Rabbits, T.H.2
  • 5
    • 0025921589 scopus 로고
    • Biology of the human γδ T-cell receptor
    • Porcelli SA, Brenner MB, Band H: Biology of the human γδ T-cell receptor. Immunol Rev 1991;120:137-183.
    • (1991) Immunol Rev , vol.120 , pp. 137-183
    • Porcelli, S.A.1    Brenner, M.B.2    Band, H.3
  • 7
    • 0025782480 scopus 로고
    • A major fraction of human intraepithelial lymphocytes simultaneously expresses the γ/δ T cell receptor, the CD8 accessory molecule and preferentially uses the Vδ1 gene segment
    • Deusch K, Luling F, Reich K, Classen M, Wagner H, Pfeffer K: A major fraction of human intraepithelial lymphocytes simultaneously expresses the γ/δ T cell receptor, the CD8 accessory molecule and preferentially uses the Vδ1 gene segment. Eur J Immunol 1991;21:1053-1059.
    • (1991) Eur J Immunol , vol.21 , pp. 1053-1059
    • Deusch, K.1    Luling, F.2    Reich, K.3    Classen, M.4    Wagner, H.5    Pfeffer, K.6
  • 8
    • 1242314217 scopus 로고    scopus 로고
    • Compartmentalization of γ/δ T cells and their putative role in mucosal immunity
    • Holtmeier W: Compartmentalization of γ/δ T cells and their putative role in mucosal immunity. Crit Rev Immunol 2003;23:473-488.
    • (2003) Crit Rev Immunol , vol.23 , pp. 473-488
    • Holtmeier, W.1
  • 9
    • 0029144848 scopus 로고
    • The δ T cell receptor repertoire in human colon and peripheral blood is oligoclonal irrespective of V region usage
    • Holtmeier W, Chowers Y, Lumeng A, Morzycka-Wroblewska E, Kagnoff MF: The δ T cell receptor repertoire in human colon and peripheral blood is oligoclonal irrespective of V region usage. J Clin Invest 1995;96:1108-1117.
    • (1995) J Clin Invest , vol.96 , pp. 1108-1117
    • Holtmeier, W.1    Chowers, Y.2    Lumeng, A.3    Morzycka-Wroblewska, E.4    Kagnoff, M.F.5
  • 11
    • 0031570390 scopus 로고    scopus 로고
    • The TCR-δ repertoire in human intestine undergoes characteristic changes during fetal to adult development
    • Holtmeier W, Witthöft T, Hennemann A, Winter HS, Kagnoff MF: The TCR-δ repertoire in human intestine undergoes characteristic changes during fetal to adult development. J Immunol 1997;158:5632-5641.
    • (1997) J Immunol , vol.158 , pp. 5632-5641
    • Holtmeier, W.1    Witthöft, T.2    Hennemann, A.3    Winter, H.S.4    Kagnoff, M.F.5
  • 13
    • 0028888156 scopus 로고
    • CDR3-independent γδ Vδ1+ T cell expansion in the peripheral blood of HIV-infected persons
    • Boullier S, Cochet M, Poccia F, Gougeon ML: CDR3-independent γδ Vδ1+ T cell expansion in the peripheral blood of HIV-infected persons. J Immunol 1995;154:1418-1431.
    • (1995) J Immunol , vol.154 , pp. 1418-1431
    • Boullier, S.1    Cochet, M.2    Poccia, F.3    Gougeon, M.L.4
  • 14
    • 0029898216 scopus 로고    scopus 로고
    • Peripheral Vγ9/Vδ2 T cell deletion and anergy to nonpeptidic mycobacterial antigens in asymptomatic HIV-1-infected persons
    • Poccia F, Boullier S, Lecoeur H, Cochet M, Poquet Y, Colizzi V, Fournie JJ, Gougeon ML: Peripheral Vγ9/Vδ2 T cell deletion and anergy to nonpeptidic mycobacterial antigens in asymptomatic HIV-1-infected persons. J Immunol 1996;157:449-461.
    • (1996) J Immunol , vol.157 , pp. 449-461
    • Poccia, F.1    Boullier, S.2    Lecoeur, H.3    Cochet, M.4    Poquet, Y.5    Colizzi, V.6    Fournie, J.J.7    Gougeon, M.L.8
  • 17
    • 0024276527 scopus 로고
    • Limited diversity of gamma/delta antigen receptor genes of Thy-1+ dendritic epidermal cells
    • Asarnow DM, Kuziel WA, Bonyhadi M, Tigelaar RE, Tucker PW, Allison JP: Limited diversity of gamma/delta antigen receptor genes of Thy-1+ dendritic epidermal cells. Cell 1988;55:837-847.
    • (1988) Cell , vol.55 , pp. 837-847
    • Asarnow, D.M.1    Kuziel, W.A.2    Bonyhadi, M.3    Tigelaar, R.E.4    Tucker, P.W.5    Allison, J.P.6
  • 18
    • 0022475348 scopus 로고
    • Diversity of murine γ-genes and expression in fetal and adult lymphocytes
    • Heilig JS, Tonegawa S: Diversity of murine γ-genes and expression in fetal and adult lymphocytes. Nature 1986;322:836-840.
    • (1986) Nature , vol.322 , pp. 836-840
    • Heilig, J.S.1    Tonegawa, S.2
  • 19
    • 0025166299 scopus 로고
    • Origin of Thy-1+ dendritic epidermal cells of adult mice from fetal thymic precursors
    • Havran WL, Allison JP: Origin of Thy-1+ dendritic epidermal cells of adult mice from fetal thymic precursors. Nature 1990;344:68-70.
    • (1990) Nature , vol.344 , pp. 68-70
    • Havran, W.L.1    Allison, J.P.2
  • 20
    • 0025731019 scopus 로고
    • Circulating CD3+/T cell receptor Vγ3+ fetal murine thymocytes home to the skin and give rise to proliferating dendritic epidermal cells
    • Payer E, Elbe A, Stingl G: Circulating CD3+/T cell receptor Vγ3+ fetal murine thymocytes home to the skin and give rise to proliferating dendritic epidermal cells. J Immunol 1991;146:2536-2543.
    • (1991) J Immunol , vol.146 , pp. 2536-2543
    • Payer, E.1    Elbe, A.2    Stingl, G.3
  • 22
    • 13544256622 scopus 로고    scopus 로고
    • Intestinal γδ T cells develop in mice lacking thymus, all lymph nodes, Peyer's patches, and isolated lymphoid follicles
    • Nonaka S, Naito T, Chen H, Yamamoto M, Moro K, Kiyono H, Hamada H, Ishikawa H: Intestinal γδ T cells develop in mice lacking thymus, all lymph nodes, Peyer's patches, and isolated lymphoid follicles. J Immunol 2005;174:1906-1912.
    • (2005) J Immunol , vol.174 , pp. 1906-1912
    • Nonaka, S.1    Naito, T.2    Chen, H.3    Yamamoto, M.4    Moro, K.5    Kiyono, H.6    Hamada, H.7    Ishikawa, H.8
  • 23
    • 0036166387 scopus 로고    scopus 로고
    • Chemokines and the tissue-specific migration of lymphocytes
    • Kunkel EJ, Butcher EC: Chemokines and the tissue-specific migration of lymphocytes. Immunity 2002;16:1-4.
    • (2002) Immunity , vol.16 , pp. 1-4
    • Kunkel, E.J.1    Butcher, E.C.2
  • 25
    • 0035525789 scopus 로고    scopus 로고
    • Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- And B-cell development and a reduction in T-cell receptor γδ+ gut intraepithelial lymphocytes
    • Wurbel MA, Malissen M, Guy-Grand D, Meffre E, Nussenzweig MC, Richelme M, Carrier A, Malissen B: Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor γδ+ gut intraepithelial lymphocytes. Blood 2001;98:2626-2632.
    • (2001) Blood , vol.98 , pp. 2626-2632
    • Wurbel, M.A.1    Malissen, M.2    Guy-Grand, D.3    Meffre, E.4    Nussenzweig, M.C.5    Richelme, M.6    Carrier, A.7    Malissen, B.8
  • 28
    • 0035914708 scopus 로고    scopus 로고
    • CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin
    • Reiss Y, Proudfoot AE, Power CA, Campbell JJ, Butcher EC: CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin. J Exp Med 2001;194:1541-1547.
    • (2001) J Exp Med , vol.194 , pp. 1541-1547
    • Reiss, Y.1    Proudfoot, A.E.2    Power, C.A.3    Campbell, J.J.4    Butcher, E.C.5
  • 31
    • 1242276411 scopus 로고    scopus 로고
    • Features and functions of γδ T lymphocytes: Focus on chemokines and their receptors
    • Kabelitz D, Wesch D: Features and functions of γδ T lymphocytes: Focus on chemokines and their receptors. Crit Rev Immunol 2003;23:339-370.
    • (2003) Crit Rev Immunol , vol.23 , pp. 339-370
    • Kabelitz, D.1    Wesch, D.2
  • 33
    • 7244248660 scopus 로고    scopus 로고
    • CCL25/CCR9 promotes the induction and function of CD103 on intestinal intraepithelial lymphocytes
    • Ericsson A, Svensson M, Arya A, Agace WA: CCL25/CCR9 promotes the induction and function of CD103 on intestinal intraepithelial lymphocytes. Eur J Immunol 2004;34:2720-2729.
    • (2004) Eur J Immunol , vol.34 , pp. 2720-2729
    • Ericsson, A.1    Svensson, M.2    Arya, A.3    Agace, W.A.4
  • 37
    • 0035575734 scopus 로고    scopus 로고
    • Human Vγ2Vδ2 T cells produce IFN-γ and TNF-α with an on/off/on cycling pattern in response to live bacterial products
    • Wang L, Das H, Kamath A, Bukowski JF: Human Vγ2Vδ2 T cells produce IFN-γ and TNF-α with an on/off/on cycling pattern in response to live bacterial products. J Immunol 2001;167:6195-6201.
    • (2001) J Immunol , vol.167 , pp. 6195-6201
    • Wang, L.1    Das, H.2    Kamath, A.3    Bukowski, J.F.4
  • 38
    • 0032513388 scopus 로고    scopus 로고
    • Recognition of stress-induced MHC molecules by intestinal epithelial γδ T cells
    • Groh V, Steinle A, Bauer S, Spies T: Recognition of stress-induced MHC molecules by intestinal epithelial γδ T cells. Science 1998;279:1737-1740.
    • (1998) Science , vol.279 , pp. 1737-1740
    • Groh, V.1    Steinle, A.2    Bauer, S.3    Spies, T.4
  • 39
    • 0032514613 scopus 로고    scopus 로고
    • Diversification, expression and γδ T cell recognition of evolutionarily distant members of the MIC family of major histocompatibility class I-related molecules
    • Steinle A, Groh V, Spies T: Diversification, expression and γδ T cell recognition of evolutionarily distant members of the MIC family of major histocompatibility class I-related molecules. Proc Natl Acad Sci USA 1998;95:12510-12515.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12510-12515
    • Steinle, A.1    Groh, V.2    Spies, T.3
  • 40
    • 0036681809 scopus 로고    scopus 로고
    • T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial γδ T cells
    • Wu J, Groh V, Spies T: T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial γδ T cells. J Immunol 2002;169:1236-1240.
    • (2002) J Immunol , vol.169 , pp. 1236-1240
    • Wu, J.1    Groh, V.2    Spies, T.3
  • 41
    • 0033618504 scopus 로고    scopus 로고
    • Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
    • Bauer S, Groh V, Wu J, Steinle A, Philipps JH, Lanier LL, Spies T: Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 1999;285:727-729.
    • (1999) Science , vol.285 , pp. 727-729
    • Bauer, S.1    Groh, V.2    Wu, J.3    Steinle, A.4    Philipps, J.H.5    Lanier, L.L.6    Spies, T.7
  • 42
    • 3142781416 scopus 로고    scopus 로고
    • Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKGD2
    • Bacon L, Eagle RA, Meyer M, Easom N, Young NT, Trowsdale J: Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKGD2. J Immunol 2004;173:1078-1084.
    • (2004) J Immunol , vol.173 , pp. 1078-1084
    • Bacon, L.1    Eagle, R.A.2    Meyer, M.3    Easom, N.4    Young, N.T.5    Trowsdale, J.6
  • 46
    • 0025836121 scopus 로고
    • Recognition of self antigens by skin-derived T cells with invariant γδ antigen receptors
    • Havran WL, Chien Y, Allison J: Recognition of self antigens by skin-derived T cells with invariant γδ antigen receptors. Science 1991;252:1430-1432.
    • (1991) Science , vol.252 , pp. 1430-1432
    • Havran, W.L.1    Chien, Y.2    Allison, J.3
  • 47
    • 0028117098 scopus 로고
    • Modulation of epithelial cell growth by γδ T cells
    • Boismenu R, Havran WL: Modulation of epithelial cell growth by γδ T cells. Science 1994;266:1253-1255.
    • (1994) Science , vol.266 , pp. 1253-1255
    • Boismenu, R.1    Havran, W.L.2
  • 49
    • 0035984016 scopus 로고    scopus 로고
    • γδ T cells promote a Th1 response during coxsackievirus B3 infection in vivo: Role of Fas and Fas ligand
    • Huber S, Shi C, Budd RC: γδ T cells promote a Th1 response during coxsackievirus B3 infection in vivo: Role of Fas and Fas ligand. J Virol 2002;76:6487-6494.
    • (2002) J Virol , vol.76 , pp. 6487-6494
    • Huber, S.1    Shi, C.2    Budd, R.C.3
  • 50
    • 0028980812 scopus 로고
    • Differential production of interferon-γ and interleukin-4 in response to Th1- And Th2-stimulating pathogens by γδ T cells in vivo
    • Ferrick DA, Schrenzel MD, Mulvania T, Hsieh B, Ferlin WG, Lepper H: Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo. Nature 1995;373:255-257.
    • (1995) Nature , vol.373 , pp. 255-257
    • Ferrick, D.A.1    Schrenzel, M.D.2    Mulvania, T.3    Hsieh, B.4    Ferlin, W.G.5    Lepper, H.6
  • 51
    • 0035885874 scopus 로고    scopus 로고
    • Differentiation of resting human peripheral blood γδ T cells toward Th1- Or Th2-phenotype
    • Wesch D, Glatzel A, Kabelitz D: Differentiation of resting human peripheral blood γδ T cells toward Th1- or Th2-phenotype. Cell Immunol 2001;212:110-117.
    • (2001) Cell Immunol , vol.212 , pp. 110-117
    • Wesch, D.1    Glatzel, A.2    Kabelitz, D.3
  • 52
    • 1642347836 scopus 로고    scopus 로고
    • Intestinal intraepithelial lymphocyte γδ-T cell-derived keratinocyte growth factor modulates epithelial growth in the mouse
    • Yang H, Antony PA, Wildhaber BE, Teitelbaum DH: Intestinal intraepithelial lymphocyte γδ-T cell-derived keratinocyte growth factor modulates epithelial growth in the mouse. J Immunol 2004;172:4151-4158.
    • (2004) J Immunol , vol.172 , pp. 4151-4158
    • Yang, H.1    Antony, P.A.2    Wildhaber, B.E.3    Teitelbaum, D.H.4
  • 53
    • 0037221567 scopus 로고    scopus 로고
    • Human γδ-T lymphocytes express and synthesize connective tissue growth factor: Effect of IL-15 and TGF-β1 and comparison with αβ-T lymphocytes
    • Workalemahu G, Foerster M, Kroegel C, Braun RK: Human γδ-T lymphocytes express and synthesize connective tissue growth factor: Effect of IL-15 and TGF-β1 and comparison with αβ-T lymphocytes. J Immunol 2003;170:153-157.
    • (2003) J Immunol , vol.170 , pp. 153-157
    • Workalemahu, G.1    Foerster, M.2    Kroegel, C.3    Braun, R.K.4
  • 54
    • 1642465536 scopus 로고    scopus 로고
    • Expression and synthesis of fibroblast growth factor-9 in human γδ T-lymphocytes. Response to isopentenyl pyrophosphate and TGF-β/IL-15
    • Workalemahu G, Förster M, Krögel C: Expression and synthesis of fibroblast growth factor-9 in human γδ T-lymphocytes. Response to isopentenyl pyrophosphate and TGF-β/IL-15. J Leukoc Biol 2004;75:657-663.
    • (2004) J Leukoc Biol , vol.75 , pp. 657-663
    • Workalemahu, G.1    Förster, M.2    Krögel, C.3
  • 56
    • 0037311546 scopus 로고    scopus 로고
    • Differential mRNA expression in circulating γδ T lymphocyte subsets defines unique tissue-specific functions
    • Hedges JF, Cockrell D, Jackiw L, Meissner N, Jutila MA: Differential mRNA expression in circulating γδ T lymphocyte subsets defines unique tissue-specific functions. J Leukoc Biol 2003;73:306-314.
    • (2003) J Leukoc Biol , vol.73 , pp. 306-314
    • Hedges, J.F.1    Cockrell, D.2    Jackiw, L.3    Meissner, N.4    Jutila, M.A.5
  • 57
    • 0037220469 scopus 로고    scopus 로고
    • Serial analysis of gene expression in circulating γδ cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles
    • Meissner N, Radke J, Hedges JF, White M, Behnke M, Bertolino S, Abrahamsen M, Jutila MA: Serial analysis of gene expression in circulating γδ cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles. J Immunol 2003;170:356-364.
    • (2003) J Immunol , vol.170 , pp. 356-364
    • Meissner, N.1    Radke, J.2    Hedges, J.F.3    White, M.4    Behnke, M.5    Bertolino, S.6    Abrahamsen, M.7    Jutila, M.A.8
  • 58
    • 0141799911 scopus 로고    scopus 로고
    • Defensins: Antimicrobial peptides of innate immunity
    • Ganz T: Defensins: Antimicrobial peptides of innate immunity. Nat Rev Immunol 2003;3:710-720.
    • (2003) Nat Rev Immunol , vol.3 , pp. 710-720
    • Ganz, T.1
  • 59
    • 2542480000 scopus 로고    scopus 로고
    • Multiple roles of antimicrobial defensins, cathelicidins and eosinophil-derived neurotoxin in host defense
    • Yang D, Biragyn A, Hoover DM, Lubkowski J, Oppenheim JJ: Multiple roles of antimicrobial defensins, cathelicidins and eosinophil-derived neurotoxin in host defense. Annu Rev Immunol 2004;22:181-215.
    • (2004) Annu Rev Immunol , vol.22 , pp. 181-215
    • Yang, D.1    Biragyn, A.2    Hoover, D.M.3    Lubkowski, J.4    Oppenheim, J.J.5
  • 60
    • 0037195896 scopus 로고    scopus 로고
    • RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin
    • Harder J, Schröder JM: RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin. J Biol Chem 2002;277:46779-46784.
    • (2002) J Biol Chem , vol.277 , pp. 46779-46784
    • Harder, J.1    Schröder, J.M.2
  • 62
    • 0024391711 scopus 로고
    • Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity
    • Lehrer RI, Barton A, Daher KA, Harwig SS, Ganz T, Selsted ME: Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity. J Clin Invest 1989;84:553-561.
    • (1989) J Clin Invest , vol.84 , pp. 553-561
    • Lehrer, R.I.1    Barton, A.2    Daher, K.A.3    Harwig, S.S.4    Ganz, T.5    Selsted, M.E.6
  • 66
    • 0035877995 scopus 로고    scopus 로고
    • Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3
    • Sorensen OE, Follin P, Johnsen AH, Calafat J, Tjabringa GS, Hiemstra PS, Borregaard N: Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3. Blood 2001;97:3951-3959.
    • (2001) Blood , vol.97 , pp. 3951-3959
    • Sorensen, O.E.1    Follin, P.2    Johnsen, A.H.3    Calafat, J.4    Tjabringa, G.S.5    Hiemstra, P.S.6    Borregaard, N.7
  • 67
    • 0036785559 scopus 로고    scopus 로고
    • The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses
    • Scott MG, Davidson DJ, Gold MR, Bowdish D, Hancock REW: The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses. J Immunol 2002;169:3883-3891.
    • (2002) J Immunol , vol.169 , pp. 3883-3891
    • Scott, M.G.1    Davidson, D.J.2    Gold, M.R.3    Bowdish, D.4    Hancock, R.E.W.5
  • 68
    • 1842581655 scopus 로고    scopus 로고
    • 7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1β processing and release
    • 7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1β processing and release. J Immunol 2004;172:4987-4994.
    • (2004) J Immunol , vol.172 , pp. 4987-4994
    • Eisner, A.1    Duncan, M.2    Gavrilin, M.3    Wewers, M.D.4
  • 70
    • 0346996865 scopus 로고    scopus 로고
    • The antimicrobial peptide LL-37 activates innate immunity and airway epithelial surface by transactivation of the epidermal growth factor receptor
    • Tjabringa GS, Aarbiou J, Ninaber DK, Drijifhout JW, Sorensen O, Borregaard N, Rabe KF, Hiemstra PS: The antimicrobial peptide LL-37 activates innate immunity and airway epithelial surface by transactivation of the epidermal growth factor receptor. J Immunol 2003;171:6690-6696.
    • (2003) J Immunol , vol.171 , pp. 6690-6696
    • Tjabringa, G.S.1    Aarbiou, J.2    Ninaber, D.K.3    Drijifhout, J.W.4    Sorensen, O.5    Borregaard, N.6    Rabe, K.F.7    Hiemstra, P.S.8
  • 71
    • 1542724426 scopus 로고    scopus 로고
    • The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes
    • Bowdish DME, Davidson DJ, Speert DP, Hancock REW: The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes. J Immunol 2004;172:3758-3765.
    • (2004) J Immunol , vol.172 , pp. 3758-3765
    • Bowdish, D.M.E.1    Davidson, D.J.2    Speert, D.P.3    Hancock, R.E.W.4
  • 72
    • 0029007198 scopus 로고
    • hCAP-18, a cathelin/probactenecin-like protein of human neutrophil specific granules
    • Cowland JB, Johnsen AH, Borregaard N: hCAP-18, a cathelin/probactenecin- like protein of human neutrophil specific granules. FEBS Lett 1995;368:173-176.
    • (1995) FEBS Lett , vol.368 , pp. 173-176
    • Cowland, J.B.1    Johnsen, A.H.2    Borregaard, N.3
  • 74
    • 0345074069 scopus 로고    scopus 로고
    • Cutting edge: Mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide
    • Di Nardo A, Vitiello A, Gallo RL: Cutting edge: Mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide. J Immunol 2003;170:2274-2278.
    • (2003) J Immunol , vol.170 , pp. 2274-2278
    • Di Nardo, A.1    Vitiello, A.2    Gallo, R.L.3
  • 76
    • 0036040263 scopus 로고    scopus 로고
    • Expression of β-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells
    • Duits LA, Ravensbergen B, Rademaker M, Hiemstra PS, Nibbering PH: Expression of β-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells. Immunology 2002;106:517-525.
    • (2002) Immunology , vol.106 , pp. 517-525
    • Duits, L.A.1    Ravensbergen, B.2    Rademaker, M.3    Hiemstra, P.S.4    Nibbering, P.H.5
  • 79
    • 1542514772 scopus 로고    scopus 로고
    • A keratinocyte-responsive γδ TCR is necessary for dendritic epidermal T cell activation by damaged keratinocytes and maintenance in the epidermis
    • Jameson JM, Cauvi G, Witherden DA, Havran WL: A keratinocyte-responsive γδ TCR is necessary for dendritic epidermal T cell activation by damaged keratinocytes and maintenance in the epidermis. J Immunol 2004;172:3573-3579.
    • (2004) J Immunol , vol.172 , pp. 3573-3579
    • Jameson, J.M.1    Cauvi, G.2    Witherden, D.A.3    Havran, W.L.4
  • 80
    • 0028117098 scopus 로고
    • Modulation of epithelial cell growth by intraepithelial γδ T cells
    • Boismenu R, Havran WL: Modulation of epithelial cell growth by intraepithelial γδ T cells. Science 1994;266:1253-1255.
    • (1994) Science , vol.266 , pp. 1253-1255
    • Boismenu, R.1    Havran, W.L.2
  • 82
    • 0036534776 scopus 로고    scopus 로고
    • Resident skin-specific gammadelta T cells provide local, nonredundant regulation of cutaneous inflammation
    • Girardi M, Lewis J, Glusac E, Filler RB, Geng L, Hayday AC, Tigelaar RE: Resident skin-specific gammadelta T cells provide local, nonredundant regulation of cutaneous inflammation. J Exp Med 2002;195:855-867.
    • (2002) J Exp Med , vol.195 , pp. 855-867
    • Girardi, M.1    Lewis, J.2    Glusac, E.3    Filler, R.B.4    Geng, L.5    Hayday, A.C.6    Tigelaar, R.E.7
  • 83
    • 0035984487 scopus 로고    scopus 로고
    • γδ T cells regulate the development of hapten-specific CD8+ effector T cells in contact hypersensitivity responses
    • Guan H, Zu G, Slater M, Elmets C, Xu H: γδ T cells regulate the development of hapten-specific CD8+ effector T cells in contact hypersensitivity responses. J Invest Dermatol 2002;119:137-142.
    • (2002) J Invest Dermatol , vol.119 , pp. 137-142
    • Guan, H.1    Zu, G.2    Slater, M.3    Elmets, C.4    Xu, H.5
  • 84
    • 0037363585 scopus 로고    scopus 로고
    • Immunoregulation by γδ T cells
    • Hayday A, Tigelaar R: Immunoregulation by γδ T cells. Nat Rev Immunol 2003;3:233-242.
    • (2003) Nat Rev Immunol , vol.3 , pp. 233-242
    • Hayday, A.1    Tigelaar, R.2
  • 86
    • 0041884744 scopus 로고    scopus 로고
    • The distinct contributions of murine T cell receptor (TCR)γδ+ and TCRαβ+ T cells to different stages of chemically induced skin cancer
    • Girardi M, Glusac E, Filler RB, Roberts SJ, Propperova I, Lewis J, Tigelaar RE, Hayday AC: The distinct contributions of murine T cell receptor (TCR)γδ+ and TCRαβ+ T cells to different stages of chemically induced skin cancer. J Exp Med 2003;198:747-755.
    • (2003) J Exp Med , vol.198 , pp. 747-755
    • Girardi, M.1    Glusac, E.2    Filler, R.B.3    Roberts, S.J.4    Propperova, I.5    Lewis, J.6    Tigelaar, R.E.7    Hayday, A.C.8
  • 88
    • 4644366900 scopus 로고    scopus 로고
    • Frontline: Interferon regulatory factor-1 as a protective gene in intestinal inflammation: Role of TCR γδ T cells and interleukin-18-binding protein
    • Siegmund B, Sennello JA, Lehr HA, Senaldi G, Dinarello CA, Fantuzzi G: Frontline: Interferon regulatory factor-1 as a protective gene in intestinal inflammation: Role of TCR γδ T cells and interleukin-18-binding protein. Eur J Immunol 2004;34:2356-2364.
    • (2004) Eur J Immunol , vol.34 , pp. 2356-2364
    • Siegmund, B.1    Sennello, J.A.2    Lehr, H.A.3    Senaldi, G.4    Dinarello, C.A.5    Fantuzzi, G.6
  • 89
    • 0029131501 scopus 로고
    • Intra-epithelial lymphocytes. Evidence for regional specialization and extrathymic maturation in the human gut
    • Lundquist C, Baranov V, Hammarström S, Athlin L, Hammarström ML: Intra-epithelial lymphocytes. Evidence for regional specialization and extrathymic maturation in the human gut. Int Immunol 1995;7:1473-1487.
    • (1995) Int Immunol , vol.7 , pp. 1473-1487
    • Lundquist, C.1    Baranov, V.2    Hammarström, S.3    Athlin, L.4    Hammarström, M.L.5
  • 90
    • 0033944066 scopus 로고    scopus 로고
    • Characterisation of mucosal lymphoid aggregates in ulcerative colitis: Immune cell phenotype and TCR γ/δ expression
    • Yeung MMW, Melgar S, Baranov V, Oberg A, Danielsson A, Hammarström S, Hammarström ML: Characterisation of mucosal lymphoid aggregates in ulcerative colitis: Immune cell phenotype and TCR γ/δ expression. Gut 2000;47:215-227.
    • (2000) Gut , vol.47 , pp. 215-227
    • Yeung, M.M.W.1    Melgar, S.2    Baranov, V.3    Oberg, A.4    Danielsson, A.5    Hammarström, S.6    Hammarström, M.L.7
  • 92
    • 0025807511 scopus 로고
    • Immunohistochemical characterization, distribution, and ultrastructure of lymphocytes bearing T-cell receptor γ/δ in inflammatory bowel disease
    • Fukushima K, Masuda T, Ohtani H, Sasaki I, Funayama Y, Matsuno S, Nagura H: Immunohistochemical characterization, distribution, and ultrastructure of lymphocytes bearing T-cell receptor γ/δ in inflammatory bowel disease. Gastroenterology 1991;101:670-678.
    • (1991) Gastroenterology , vol.101 , pp. 670-678
    • Fukushima, K.1    Masuda, T.2    Ohtani, H.3    Sasaki, I.4    Funayama, Y.5    Matsuno, S.6    Nagura, H.7
  • 94
    • 0029979529 scopus 로고    scopus 로고
    • Increased frequency of abnormal γ/δ T cells in blood of patients with inflammatory bowel disease
    • Söderström K, Bucht A, Halapi E, Grönberg A, Magnusson I, Kiessling R: Increased frequency of abnormal γ/δ T cells in blood of patients with inflammatory bowel disease. J Immunol 1996;156:2331-2339.
    • (1996) J Immunol , vol.156 , pp. 2331-2339
    • Söderström, K.1    Bucht, A.2    Halapi, E.3    Grönberg, A.4    Magnusson, I.5    Kiessling, R.6
  • 96
    • 4444298192 scopus 로고    scopus 로고
    • Diverse populations of T cells with NK cell receptors accumulate in the human intestine in health and in colorectal cancer
    • O'Keeffe J, Doherty DG, Kenna T, Sheahan K, O'Donoghe DP, Hyland JM, O'Farrelly C: Diverse populations of T cells with NK cell receptors accumulate in the human intestine in health and in colorectal cancer. Eur J Immunol 2004;34:2110-2118.
    • (2004) Eur J Immunol , vol.34 , pp. 2110-2118
    • O'Keeffe, J.1    Doherty, D.G.2    Kenna, T.3    Sheahan, K.4    O'Donoghe, D.P.5    Hyland, J.M.6    O'Farrelly, C.7
  • 97
    • 0029035233 scopus 로고
    • Regulatory role of γδ T cells in uterine intraepithelial lymphocytes in maternal antifetal response
    • Suzuki T, Hiromatsu K, Ando Y, Okamoto T, Tomoda Y, Yoshikai Y: Regulatory role of γδ T cells in uterine intraepithelial lymphocytes in maternal antifetal response. J Immunol 1995;154:4476-4484.
    • (1995) J Immunol , vol.154 , pp. 4476-4484
    • Suzuki, T.1    Hiromatsu, K.2    Ando, Y.3    Okamoto, T.4    Tomoda, Y.5    Yoshikai, Y.6
  • 100
    • 2942525398 scopus 로고    scopus 로고
    • Accumulation of γδ T cells in the lungs and their regulatory role in Th1 response and host defense against pulmonary infection with Cryptococcus neoformans
    • Uezu K, Kawakami K, Miyagi K, Kinjo Y, Kinjo T, Ishikawa H, Saito A: Accumulation of γδ T cells in the lungs and their regulatory role in Th1 response and host defense against pulmonary infection with Cryptococcus neoformans. J Immunol 2004;172:7629-7634.
    • (2004) J Immunol , vol.172 , pp. 7629-7634
    • Uezu, K.1    Kawakami, K.2    Miyagi, K.3    Kinjo, Y.4    Kinjo, T.5    Ishikawa, H.6    Saito, A.7


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