γδT cells regulate the development of hapten-specific CD8+ effector T cells in contact hypersensitivity responses

Journal of Investigative Dermatology

Volumn 119, Issue 1, 2002, Pages 137-142

  Guan, Hongbing ^a   Zu, Guorui ^a   Slater, Marlon ^a   Elmets, Craig ^a   Xu, Hui ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Cellular activation; Delayed type hypersensitivity; Skin; T lymphocytes

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; HAPTEN; INTERLEUKIN 10; INTERLEUKIN 4; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; CONTACT ALLERGY; CONTROLLED STUDY; DOWN REGULATION; HAPTEN CARRIER COMPLEX; LYMPH NODE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; WILD TYPE; ANIMAL; ARTICLE; BIOSYNTHESIS; C57BL MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CULTURE; CONTACT DERMATITIS; CYTOLOGY; DELAYED HYPERSENSITIVITY; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; SKIN;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DERMATITIS, CONTACT; HAPTENS; HYPERSENSITIVITY, DELAYED; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-4; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; SKIN;

EID: 0035984487     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2002.01830.x     Document Type: Conference Paper

References (43)

1. Anderson C, Hehr A, Robbins R, Hasan R, Athar M, Mukhtar H, Elmets CA: Metabolic requirements for induction of contact hypersensitivity to immunotoxic polyaromatic hydrocarbons. J Immunol 155:3530-3537, 1995
2. Askenase PW, Szczepanik M, Ptak M, Paliwal V, Ptak W: Gamma delta T cells in normal spleen assist immunized alpha beta T cells in the adoptive cell transfer of contact sensitivity. Effect of Bordetella pertussis, cyclophosphamide, and antibodies to determinants on suppressor cells. J Immunol 154:3644-3653, 1995
3. Berg DJ, Leach MW, Kuhn R, Rajewsky K, Muller W, Davidson NJ, Rennick D: Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses. J Exp Med 182:99-108, 1995
4. Born W, Cady C, Jones-Carson J, Mukasa A, Lahn M, O'Brien R: Immunoregulatory functions of gamma delta T cells. Adv Immunol 71:77-144, 1999
5. De Libero G: Sentinel function of broadly reactive human gamma delta T cells. Immunol Today 18:22-26, 1997
6. Dieli F, Asherson GL, Romano GC, Sireci G, Gervasi F, Salerno A: IL-4 is essential for the systemic transfer of delayed hypersensitivity by T cell lines. Role of gamma/delta cells. J Immunol 152:2698-2704, 1994
7. + T cell development from regulatory T helper to effector T helper cells alters the contact hypersensitivity response. Eur J Immunol 26:2606-2612, 1996
8. D'Souza CD, Cooper AM, Frank AA, Mazzaccaro RJ, Bloom BR, Orme IM: An anti-inflammatory role for gamma delta T lymphocytes in acquired immunity to Mycobacterium tuberculosis. J Immunol 158:1217-1221, 1997
9. Egan PJ, Carding SR: Downmodulation of the inflammatory response to bacterial infection by gammadelta T cells cytotoxic for activated macrophages. J Exp Med 191:2145-2158, 2000
10. Ferguson TA, Dube P, Griffith TS: Regulation of contact hypersensitivity by interleukin 10. J Exp Med 179:1597-1604, 1994
11. Ferrick DA, Schrenzel MD, Mulvania T, Hsieh B, Ferlin WG, Lepper H: Differential production of interferon-gamma and interleukin-4 in response to Th1- and Th2-stimulating pathogens by gamma delta T cells in vivo. Nature 373:255-257, 1995
12. Fujihashi K, McGhee JR, Kweon MN, et al: Gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses. J Exp Med 183:1929-1935, 1996
13. Fujihashi K, Dohi T, Kweon MN, et al: Gammadelta T cells regulate mucosally induced tolerance in a dose-dependent fashion. Intl Immunol 11:1907-1916, 1999
14. Gocinski BL, Tigelaar RE: Roles of CD4+ and CD8+ T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion. J Immunol 144:4121-4128, 1990
15. Grabbe S, Schwarz T: Immunregulatory mechanisms involved in elicitation of allergic contact hypersensitivity. Immunol Today 19:37-44, 1998
16. Grusby MJ, Auchincloss H Jr, Lee R, et al: Mice lacking major histocompatibility complex class I and class II molecules. Proc Natl Acad Sci USA 90:3913-3917, 1993
17. Hauser C: The interaction between Langerhans cells and CD4+ T cells. J Dermatol 19:722-725, 1992
18. Hayday AC: γδ cells: A right time and a right place for a conserved third way of protection. Annu Rev Immunol 18:975-1026, 2000
19. Hein WR, Mackay CR: Prominence of γ-δ T-cells in the ruminant immune system. Immunol Today 12:30-34, 1991
20. Huber H, Descossy P, van Brandwijk R, Knop J: Activation of murine epidermal TCR-gamma delta+ T cells by keratinocytes treated with contact sensitizers. J Immunol 155:2888-2894, 1995
21. Huber SA, Kupperman J, Newell MK: Hormonal regulation of CD4 (+) T-cell responses in coxsackievirus B3-induced myocarditis in mice. J Virol 73:4689-4695, 1999
22. Itohara S, Mombaerts P, Lafaille J, et al: T cell receptor delta gene mutant mice: Independent generation of alpha beta T cells and programmed rearrangements of gamma delta TCR genes. Cell 72:337-348, 1993
23. Kaufmann SH, Blum C, Yamamoto S: Crosstalk between alpha/beta T cells and gamma/delta T cells in vivo: Activation of alpha/beta T-cell responses after gamma/delta T-cell modulation with the monoclonal antibody GL3. Proc Natl Acad Sci USA 90:9620-9624, 1993
24. Ke Y, Pearce K, Lake JP, Ziegler HK, Kapp JA: Gamma delta T lymphocytes regulate the induction and maintenance of oral tolerance. J Immunol 158:3610-3618, 1997
25. Kehren J, Desvignes C, Krasteva M, et al: Cytotoxicity is mandatory for CD8 (+) T cell-mediated contact hypersensitivity. J Exp Med 189:779-786, 1999
26. Ladel CH, Blum C, Kaufmann SH: Control of natural killer cell-mediated innate resistance against the intracellular pathogen Listeria monocytogenes by gamma/delta T lymphocytes. Infect Immun 64:1744-1749, 1996
27. Maloy KJ, Odermatt B, Hengartner H, Zinkernagel RM: Interferon gamma-producing gammadelta T cell-dependent antibody isotype switching in the absence of germinal center formation during virus infection. Proc Natl Acad Sci USA 95:1160-1165, 1998
28. Mukasa A, Hiromatsu K, Matsuzaki G, O'Brien R, Born W, Nomoto K: Bacterial infection of the testis leading to autoaggressive immunity triggers apparently opposed responses of alpha beta and gamma delta T cells. J Immunol 155:2047-2056, 1995
29. Schild H, Mavaddat N, Litzenberger C, et al: The nature of major histocompatibility complex recognition by gamma delta T cells. Cell 76:29-37, 1994
30. Szczepanik M, Anderson LR, Ushio H, Ptak W, Owen MJ, Hayday AC, Askenase PW: Gamma delta T cells from tolerized alpha beta T cell receptor (TCR)-deficient mice inhibit contact sensitivity-effector T cells in vivo, and their interferon-gamma production in vitro. J Exp Med 184:2129-2139, 1996
31. Szczepanik M, Nowak B, Askenase PW, Ptak W: Cross-talk between gammadelta T lymphocytes and immune cells in humoral response. Immunology 95:612-617, 1998
32. Tang A, Judge TA, Turka LA: Blockade of CD40-CD40 ligand pathway induces tolerance in murine contact hypersensitivity. Eur J Immunol 27:3143-3150, 1997
33. Vincent MS, Roessner K, Lynch D, et al: Apoptosis of Fashigh CD4+ synovial T cells by borrelia-reactive Fas-ligand (high) gamma delta T cells in Lyme arthritis. J Exp Med 184:2109-2117, 1996
34. Wang B, Fujisawa H, Zhuang L, et al: CD4+ Th1 and CD8+ type 1 cytotoxic T cells both play a crucial role in the full development of contact hypersensitivity. J Immunol 165:6783-6790, 2000
35. Wang LF, Sun CC, Wu JT, Lin RH: Epicutaneous administration of hapten through patch application augments TH2 responses which can downregulate the elicitation of murine contact hypersensitivity. Clin Exp Allergy 29:271-279, 1999
36. Wen L, Roberts SJ, Viney JL, et al: Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in alpha beta (+) T cells. Nature 369:654-658, 1994
37. Wen L, Barber DF, Pao F, Wong FS, Owen MJ, Hayday A: Primary γδT cell clones can be defined phenotypically and functionally as Th1/Th2 cells and illustrate the association of CD4 with Th2 differentiation. J Immunol 160:1965-1974, 1998
38. Xu H, Dilulio NA, Fairchild RL: T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: Interferon γ-producing (Tc1) effector CD8+ T cells and interleukin 4/IL-10-producing (Th2) negative regulatory CD4+ T cells. J Exp Med 183:1001-1012, 1996
39. Xu H, Banerjee A, Dilulio NA, Fairchild RL: Development of effector CD8+ T cells in contact hypersensitivity occurs independently of CD4+ T cells. J Immunol 158:4721-4728, 1997a
40. Xu H, Heeger PS, Fairchild RL: Distinct roles of B7-1 and B7-2 determinants during priming of effector CD8+ Tc1 and regulatory CD4+ Th2 cells for contact hypersensitivity. J Immunol 159:4217-4226, 1997b
41. Xu H, Guan H, Zu G, Bullard D, Hanson J, Slater M, Elmets CA: The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node. Eur J Immunol 31:3085-3093, 2001
42. Yokozeki H, Watanabe K, Igawa K, Miyazaki Y, Katayama I, Nishioka K: Gammadelta T cells assist alphabeta T cells in the adoptive transfer of contact hypersensitivity to para-phenylenediamine. Clin Exp Immunol 125:351-359, 2001
43. Zuany-Amorim C, Ruffie C, Haile S, Vargaftig BB, Pereira P, Pretolani M: Requirement for gammadelta T cells in allergic airway inflammation. Science 280:1265-1267, 1998