Tertiary interactions stabilise the C-terminal region of human glutathione transferase A1-1: A crystallographic and calorimetric study

Journal of Molecular Biology

Volumn 349, Issue 4, 2005, Pages 825-838

  Kuhnert, Diane C ^a   Sayed, Yasien ^a   Mosebi, Salerwe ^a   Sayed, Muhammed ^b   Sewell, Trevor ^c   Dirr, Heini W ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b UNIVERSITY OF THE WESTERN CAPE   (South Africa)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Conformational dynamics; Crystallography; Isothermal titration calorimetry; Protein ligand interaction; Thermodynamics

Indexed keywords

GLUTATHIONE; GLUTATHIONE TRANSFERASE A1; ISOENZYME; ISOLEUCINE; MUTANT PROTEIN; S HEXYLGLUTATHIONE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME LOCALIZATION; ENZYME STABILITY; ENZYME STRUCTURE; LIGAND BINDING; MICROCALORIMETRY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MUTANT; PRIORITY JOURNAL; PROTEIN BINDING; THERMODYNAMICS; WILD TYPE; X RAY CRYSTALLOGRAPHY;

EID: 19444371485     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.04.025     Document Type: Article

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