Residue 219 Impacts on the Dynamics of the C-Terminal Region in Glutathione Transferase A1-1: Implications for Stability and Catalytic and Ligandin Functions

Biochemistry

Volumn 42, Issue 51, 2003, Pages 15326-15332

  Mosebi, Salerwe ^a   Sayed, Yasien ^a   Burke, Jonathan ^a   Dirr, Heini W ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME ACTIVITY;

AROMATIC COMPOUNDS; CATALYST ACTIVITY; CONFORMATIONS; DYES; ENZYME INHIBITION; FLUORESCENCE; QUENCHING; STOICHIOMETRY; WATER;

ENZYMES;

1 CHLORO 2,4 DINITROBENZENE; 8 ANILINO 1 NAPHTHALENESULFONIC ACID; ALANINE; AMINO ACID; ANION; DYE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; ISOLEUCINE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CATALYST; DYNAMICS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME STABILITY; ENZYME SUBSTRATE COMPLEX; FLUORESCENCE; HUMAN; HYDROPHOBICITY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; STOICHIOMETRY;

ALANINE; AMINO ACID SUBSTITUTION; ANILINO NAPHTHALENESULFONATES; ANIMALS; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; ENZYME STABILITY; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; ISOLEUCINE; KINETICS; MICE; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; THERMODYNAMICS; TYROSINE;

EID: 0346963150     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035671z     Document Type: Article

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