The role of tyrosine-9 and the C-terminal helix in the catalytic mechanism of Alpha-class glutathione S-transferases

Biochemical Journal

Volumn 343, Issue 3, 1999, Pages 525-531

  Allardyce, Claire S ^a,c   McDonagh, Paul D ^a,d   Lian, Lu Yun ^a   Wolf, C Roland ^b   Roberts, Gordon C K ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c UNIVERSITY OF YORK   (United Kingdom)

^d Seattle Biomedical Research Center   (United States)

Author keywords

1 chloro 2,4 dinitrobenzene; Conjugation; Ethacrynic acid; Substrate activation

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; DITHIOTHREITOL; ETACRYNIC ACID; GLUTATHIONE; GLUTATHIONE TRANSFERASE; MERCAPTOETHANOL; MUTANT PROTEIN; PHENYLALANINE; TYROSINE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMINO ACID SUBSTITUTION; BINDING SITES; CATALYSIS; DINITROCHLOROBENZENE; ETHACRYNIC ACID; GLUTATHIONE TRANSFERASE; ISOENZYMES; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PHENYLALANINE; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TYROSINE;

FELIS CATUS;

EID: 0033230491     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3430525     Document Type: Article

References (40)

1. Mannervik, B. (1985) Adv. Enzymol. Relat. Areas Mol. Biol. 57, 357-391
2. Hayes, J. D. and Pulford, D. J. (1995) Crit. Rev. Biochem. Mol. Biol. 30, 445-600
3. Mannervik, B., Awasthi, Y. C., Board, P. G., Hayes, J. D., Di Ilio, C., Ketterer, B., Listowsky, I., Morgenstern, R., Muramatsu, M., Pearson, W. R. et al. (1992) Biochem. J. 282, 305-306
4. Wilce, M. C. J. and Parker, M. W. (1994) Biochim. Biophys. Acta 1205, 1-18
5. Reinemer, P., Dirr, H. W., Ladenstein, R., Schaffer, J., Gallay, O. and Huber, R. (1991) EMBO J. 10, 1997-2005
6. Ji, X., Zhang, P., Armstrong, R. N. and Gilliland, G. L. (1992) Biochemistry 31, 10169-10184
7. Ji, X. H., von Rosenvinge, E. C., Johnson, W. W., Tomarev, S. I., Piatigorsky, J., Armstrong, R. N. and Gilliland, G. L. (1995) Biochemistry 34, 5317-5328
8. Sinning, I., Kleywegt, G. J., Cowan, S. W., Reinemer, P., Dirr, H. W., Huber, R., Gilliland, G. Armstrong, R. N., Ji, X., Board, P. G. et al. (1993) J. Mol. Biol. 232, 192-212
9. Dirr, H., Reinemer, P. and Huber, R. (1994) J. Mol. Biol. 243, 72-92
10. Garcia-Saez, I., Parraga, A., Phillips, M. F., Mantle, T. J. and Coll, M. (1994) J. Mol. Biol. 237, 298-314
11. Raghunathan, S., Chandross, R. J., Kretsinger, R. H., Allison, T. J., Penington, C. J. and Rule, G. S. (1994) J. Mol. Biol. 238, 815-832
12. Cameron, A. D., Sinning, I., L'Hermite, G., Olin, B., Board, P. G., Mannervik, B. and Jones, T. A. (1995) Structure 3, 717-720
13. Wilce, M. C. J., Board, P. G., Feil, S. C. and Parker, M. W. (1995) EMBO J. 14, 2133-2143
14. Bruns, C. M., Hubatsch, I., Ridderstrm, M., Mannervik, B. and Tainer, J. A. (1999) J. Mol. Biol. 288, 427-439
15. Board, P. G. and Mannervik, B. (1991) Biochem. J. 275, 171-174
16. Armstrong, R. N. (1994) Adv. Enzymol. Relat. Areas Mol. Biol. 69, 1-44
17. Dirr, H., Reinemer, P. and Huber, R. (1994) Eur. J. Biochem. 220, 645-661
18. Stenberg, G., Board, P. G. and Mannervik, B. (1991) FEBS Letts. 293, 153-155
19. Liu, S., Zhang, P., Ji, X., Johnson, W. W., Gilliland, G. L. and Armstrong, R. N. (1992) J. Biol. Chem. 267, 4296
20. Kolm, R. H., Sroga, G. E. and Mannervik, B. (1992) Biochem. J. 285, 537-540
21. McDonagh, P. D. (1998) Ph.D. Thesis, University of Leicester
22. Kunkel, T. A. (1985) Proc. Natl. Acad. Sci. U.S.A. 82, 488-492
23. McDonagh, P. D., Judah, D. J., Hayes, J. D., Lian, L.-Y., Neal, G. D., Wolf, C. R. and Roberts, G. C. K (1999) Biochem. J. 339, 95-101
24. Simula, T. P., Glancey, M. J. and Wolf, C. R. (1993) Carcinogenesis 14, 1371-1376
25. Habig, W. H., Pabst, M. J. and Jakoby, W. B. (1974) J. Biol. Chem. 249, 7130-7139
26. Allardyce, C. S. (1996) Ph.D. Thesis, University of Leicester
27. Gill, S. C. and von Hippel, P. H. (1989) Anal. Biochem. 182, 319-326
28. Briggs, G. E. and Haldane, J. B. S. (1925) Biochem. J. 19, 338-339
29. Adang, A. E. P., Brussee, J., Meyer, D. J., Coles, B., Ketterer, B., van der Gen, A. and Mulder, G. J. (1988) Biochem. J. 255, 721-724
30. Atkins, W. M., Wang, R. W., Bird, A. W., Newton, D. J. and Lu, A. Y. H. (1993) J. Biol. Chem. 268, 19188-19191
31. McTigue, M. A., Williams, D. R. and Tainer, J. A. (1995) J. Mol. Biol. 246, 21-27
32. Sluis-Cremer, N., Naidoo, N. N., Kaplan, W. H., Manoharan, T. H., Fahl, W. E. and Dirr, H. W. (1996) Eur. J. Biochem. 242, 484-488
33. Barycki, J. J. and Colman, R. F. (1997) Arch. Biochem. Biophys. 345, 16-31
34. Caccuri, A. M., Ascenzi, P., Antonini, G., Parker, M. W., Oakley, A. J., Ciessi, E., Nuccetelli, M., Battistoni, A., Bellizia, A. and Ricci, G. (1996) J. Biol. Chem. 271, 16193-16198
35. Ricci, G., Caccuri, A. M., Lo Bello, M., Rosato, N., Mei, G., Nicotra, M., Chiessi, E., Mazzetti, A. P. and Federici, G. (1996) J. Biol. Chem. 271, 16187-16192
36. Nieslanik, B. S., Dabrowski, M. J., Lyon, R. P. and Atkins, W. M. (1999) Biochemistry 38, 6971-6980
37. Principato, G. B., Danielson, U. H. and Mannervik, B. (1988) FEBS Lett. 231, 155-158
38. Widerstern, M., Bjornestedt, R. and Mannervik, B. (1996) Biochemistry 35, 7731-7742
39. Lian, L.-Y. (1998) Cell. Mol. Life Sci. 54, 359-362
40. Barycki, J. J. and Colman, R. F. (1993) Biochemistry 32, 13002-13011