In vitro activities of 2,4-diaminoquinazoline and 2,4-diaminopteridine derivatives against Plasmodium falciparum

Antimicrobial Agents and Chemotherapy

Volumn 48, Issue 10, 2004, Pages 3711-3714

  Ommeh, Sheila ^a   Nduati, Eunice ^a   Mberu, Eddy ^a   Kokwaro, Gilbert ^a   Marsh, Kevin ^a,b   Rosowsky, Andre ^d   Nzila, Alexis ^a,c  

^a KEMRI WELLCOME TRUST RESEARCH PROGRAMME   (Kenya)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 AMINO 4 DEOXY N 10 METHYLPTEROYL) 4 CARBETHOXYPIPERAZINE; 1 [N (4 AMINO 4 DEOXY N 10 METHYLPTEROYL)AMINO]ADAMANTANE; 2,4 DIAMINO 5 (2,5 DIMETHOXY N METHYLANILINO)METHYLQUINAZOLINE; 2,4 DIAMINO 5 (3,4,5 TRIMETHOXY N METHYLANILINO)METHYLQUINAZOLINE; 2,4 DIAMINO 5 [2 (2 BROMO 3,4,5 TRIMETHOXY)PHENYL]ETHYLTHIENOL[2,3 D]PYRIMIDINE; 2,4 DIAMINO 5 CHLORO 6 (2 BROMO 3,4,5 TRIMETHOXYANILINO)METHYLQUINAZOLINE; 2,4 DIAMINO 5 CHLORO 6 [2 (3,4,5 TRIMETHOXYPHENYL)ETHYL]AMINOQUINAZOLINE; 2,4 DIAMINO 5 CHLORO 6 [N (2,5 DIMETHOXYBENZYL)AMINO]QUINAZOLINE; 2,4 DIAMINO 5 CHLORO 6 [N (3,4,5 TRIMETHOXYBENZYL) N METHYLAMINO]QUINAZOLINE; 2,4 DIAMINO 5 CHLORO 6 [N (3,4,5 TRIMETHOXYBENZYL)AMINO]QUINAZOLINE; 2,4 DIAMINO 6 (2 METHOXYBENZYL) 5,6,7,8 TETRAHYDROQUINAZOLINE; 2,4 DIAMINO 6 (2 METHYLBENZYL) 5,6,7,8 TETRAHYDROQUINAZOLINE; 2,4 DIAMINO 6 (3 METHOXYBENZYL) 5,6,7,8 TETRAHYDROQUINAZOLINE; 2,4 DIAMINO 6 (4 METHOXYBENZYLIDENE) 5,6,7,8 TETRAHYDROQUINAZOLINE; 2,4 DIAMINO 6 (4 TRIFLUOROMETHOXYBENZYL) 5,6,7,8 TETRAHYDROQUINAZOLINE; 2,4 DIAMINO 6 [2 (2,5 DIMETHOXYPHENYL)ETHYL] 5 METHYLTHIENO[2,3 D]PYRIMIDINE; DAPSONE; DEXTRO,LEVO 2 [N (4 AMINO 4 DEOXY N 10 METHYLPTEROYL)]AMINOPENTANE; DEXTRO,LEVO 2 [N (4 AMINO 4 DEOXY N 10 METHYLPTEROYL)]AMINOPENTANE 1,5 DIOL; DIHYDROFOLATE REDUCTASE; METHOTREXATE ALPHA,GAMMA DI(N PROPYLAMIDE); METHOTREXATE ALPHA,GAMMA DI[3 (N,N DIMETHYLAMINO)PROPYL]AMIDE; METHOTREXATE ALPHA,GAMMA DIBENZYLAMIDE; METHOTREXATE ALPHA,GAMMA DICYCLOPENTYLAMIDE; N (4 AMINO 4 DEOXY N 10 METHYLPTEROYL)AMINOCYCLOHEXANE; PTERIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE; TETRAHYDROQUINAZOLINE DERIVATIVE; THIENO[2,3 D]PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG POTENTIATION; ENZYME INHIBITION; IC 50; IN VITRO STUDY; MULTIDRUG RESISTANCE; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

ANIMALS; ANTIMALARIALS; DAPSONE; DIHYDROPTEROATE SYNTHASE; DRUG RESISTANCE; FOLIC ACID ANTAGONISTS; PLASMODIUM FALCIPARUM; PTERIDINES; QUINAZOLINES; SACCHAROMYCES CEREVISIAE; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 4644291855     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.48.10.3711-3714.2004     Document Type: Article

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