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Volumn 47, Issue 2-3, 2000, Pages 85-118

Mycophenolate mofetil and its mechanisms of action

Author keywords

Adhesion molecules; CellCept ; Chronic rejection; Immunosuppression; Inosine monophosphate dehydrogenase; Mycophenolate mofetil; Mycophenolic acid; Nitric oxide

Indexed keywords

CELL ADHESION MOLECULE; GUANOSINE; INOSINATE DEHYDROGENASE; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

EID: 0034045586     PISSN: 01623109     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-3109(00)00188-0     Document Type: Article
Times cited : (1236)

References (161)
  • 1
    • 0041460959 scopus 로고    scopus 로고
    • Influenza vaccine antibody response in pediatric renal transplant patients treated with newer immunosuppressive agents
    • (Abstr)
    • Al-Akash S., Ettenger R., Gales B.et al. Influenza vaccine antibody response in pediatric renal transplant patients treated with newer immunosuppressive agents. J. Am. Soc. Nephrol. 9:1998;663A. (Abstr).
    • (1998) J. Am. Soc. Nephrol. , vol.9
    • Al-Akash, S.1    Ettenger, R.2    Gales, B.3
  • 2
    • 0027979333 scopus 로고
    • Effect of mycophenolic acid on Epstein-Barr virus infection of human B-lymphocytes
    • Alfieri C., Allison A.C., Kieff E. Effect of mycophenolic acid on Epstein-Barr virus infection of human B-lymphocytes. Antimicro. Agents Chemother. 38:1994;126-129.
    • (1994) Antimicro. Agents Chemother. , vol.38 , pp. 126-129
    • Alfieri, C.1    Allison, A.C.2    Kieff, E.3
  • 3
    • 0034098326 scopus 로고    scopus 로고
    • Immunosuppressive drugs: The first 50 years and a glance forward
    • Allison A.C. Immunosuppressive drugs: the first 50 years and a glance forward. Immunopharmacology. 47:2000;63-83.
    • (2000) Immunopharmacology , vol.47 , pp. 63-83
    • Allison, A.C.1
  • 4
    • 0025847662 scopus 로고
    • In vitro immunosuppressive effects of mycophenolic acid and an ester prodrug, RS-61443
    • Allison A.C., Almquist S.J., Muller C.D., Eugui E.M. In vitro immunosuppressive effects of mycophenolic acid and an ester prodrug, RS-61443. Transplant. Proc. 23(Suppl. 2):1991;10-14.
    • (1991) Transplant. Proc. , vol.23 , Issue.SUPPL. 2 , pp. 10-14
    • Allison, A.C.1    Almquist, S.J.2    Muller, C.D.3    Eugui, E.M.4
  • 5
    • 0027189955 scopus 로고
    • The design and development of an immunosuppressive drug, mycophenolate mofetil
    • Allison A.C., Eugui E.M. The design and development of an immunosuppressive drug, mycophenolate mofetil. Springer Semin. Immunopathol. 14:1993;353-380.
    • (1993) Springer Semin. Immunopathol. , vol.14 , pp. 353-380
    • Allison, A.C.1    Eugui, E.M.2
  • 6
    • 0016758998 scopus 로고
    • Immunological observations on patients with the Lesch-Nyhan syndrome, and on the role of de novo purine synthesis in lymphocyte transformation
    • Allison A.C., Hovi T., Watts R.W.E., Webster A.D.B. Immunological observations on patients with the Lesch-Nyhan syndrome, and on the role of de novo purine synthesis in lymphocyte transformation. Lancet. II:1975;1179-1183.
    • (1975) Lancet , vol.2 , pp. 1179-1183
    • Allison, A.C.1    Hovi, T.2    Watts, R.W.E.3    Webster, A.D.B.4
  • 8
    • 0027192031 scopus 로고
    • Mycophenolic acid and brequinar, inhibitors of purine and pyrimidine synthesis, block the glycosylation of adhesion molecules
    • Allison A.C., Kowalski W.J., Muller C.J.et al. Mycophenolic acid and brequinar, inhibitors of purine and pyrimidine synthesis, block the glycosylation of adhesion molecules. Transplant. Proc. 25(Suppl. 2):1993;67-70.
    • (1993) Transplant. Proc. , vol.25 , Issue.SUPPL. 2 , pp. 67-70
    • Allison, A.C.1    Kowalski, W.J.2    Muller, C.J.3
  • 9
    • 0024565485 scopus 로고
    • Cotransfection of ICAM-1 and HLA-DR reconstitutes human antigen-presenting function in mouse L cells
    • Altmann D.M., Hogg N., Trowsdale J., Wilkinson D. Cotransfection of ICAM-1 and HLA-DR reconstitutes human antigen-presenting function in mouse L cells. Nature. 338:1989;512-514.
    • (1989) Nature , vol.338 , pp. 512-514
    • Altmann, D.M.1    Hogg, N.2    Trowsdale, J.3    Wilkinson, D.4
  • 10
    • 0031155385 scopus 로고    scopus 로고
    • Perforin, Fas/Fas ligand and TNF-α pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL
    • Ando K., Hiroishi K., Kaneko T.et al. Perforin, Fas/Fas ligand and TNF-α pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL. J. Immunol. 158:1997;5283-5291.
    • (1997) J. Immunol. , vol.158 , pp. 5283-5291
    • Ando, K.1    Hiroishi, K.2    Kaneko, T.3
  • 11
    • 0028900764 scopus 로고
    • Effects of RS61443 on functional and morphological changes in chronically rejecting rat kidney allografts
    • Azuma H., Binder J., Heeman U.et al. Effects of RS61443 on functional and morphological changes in chronically rejecting rat kidney allografts. Transplantation. 59:1995;460-466.
    • (1995) Transplantation , vol.59 , pp. 460-466
    • Azuma, H.1    Binder, J.2    Heeman, U.3
  • 12
    • 0029592005 scopus 로고
    • Activation of the inducible nitric oxide synthase in brains of patients with multiple sclerosis
    • Bagasra D., Michaels F.H., Zheng Y.M.et al. Activation of the inducible nitric oxide synthase in brains of patients with multiple sclerosis. Proc. Natl. Acad. Sci. U. S. A. 92:1995;12041-12045.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 12041-12045
    • Bagasra, D.1    Michaels, F.H.2    Zheng, Y.M.3
  • 13
    • 9044246270 scopus 로고    scopus 로고
    • Increased serum nitrate concentration in cardiac transplant patients. A marker for acute allograft cellular rejection
    • Benvenuti C., Bories P.N., Loisance D. Increased serum nitrate concentration in cardiac transplant patients. A marker for acute allograft cellular rejection. Transplantation. 61:1996;745-749.
    • (1996) Transplantation , vol.61 , pp. 745-749
    • Benvenuti, C.1    Bories, P.N.2    Loisance, D.3
  • 14
    • 0019918051 scopus 로고
    • In vitro effects of mycophenolic acid and allopurinol against Leishmania tropica in human macrophages
    • Berman J.D., Webster H.K. In vitro effects of mycophenolic acid and allopurinol against Leishmania tropica in human macrophages. Antimicro. Agents Chemother. 21:1982;887-891.
    • (1982) Antimicro. Agents Chemother. , vol.21 , pp. 887-891
    • Berman, J.D.1    Webster, H.K.2
  • 15
    • 0343482534 scopus 로고
    • Cyclosporin A, lymphomata and Epstein-Barr virus
    • D.J. White. Amsterdam: Elsevier
    • Bird A.G. Cyclosporin A, lymphomata and Epstein-Barr virus. White D.J. Cyclosporin A. 1982;307-315 Elsevier, Amsterdam.
    • (1982) Cyclosporin a , pp. 307-315
    • Bird, A.G.1
  • 16
    • 0032533404 scopus 로고
    • Steroid-free immunosuppression after kidney transplantation with antithymocyte globulin induction and cyclosporine and mycophenolate mofetil maintenance therapy
    • Birkeland S.A. Steroid-free immunosuppression after kidney transplantation with antithymocyte globulin induction and cyclosporine and mycophenolate mofetil maintenance therapy. Transplantation. 66:1988;1207-1210.
    • (1988) Transplantation , vol.66 , pp. 1207-1210
    • Birkeland, S.A.1
  • 17
    • 0032987171 scopus 로고    scopus 로고
    • Mycophenolate mofetil impairs transendothelial migration of allogeneic CD4 and CD8 T-cells
    • Blaheta R.A., Leckel K., Wittig B.et al. Mycophenolate mofetil impairs transendothelial migration of allogeneic CD4 and CD8 T-cells. Transplant. Proc. 31:1999;1250-1252.
    • (1999) Transplant. Proc. , vol.31 , pp. 1250-1252
    • Blaheta, R.A.1    Leckel, K.2    Wittig, B.3
  • 18
    • 85074331779 scopus 로고    scopus 로고
    • Bullous pemphigoid treated with mycophenolate mofetil
    • Böhm M., Beissert S., Schwartz T.et al. Bullous pemphigoid treated with mycophenolate mofetil. Lancet. 1997;349-351.
    • (1997) Lancet , pp. 349-351
    • Böhm, M.1    Beissert, S.2    Schwartz, T.3
  • 19
    • 0017157814 scopus 로고
    • Biological effects of cyclosporein A: A new anti-lymphocyte agent
    • Borel J.F., Feurer C., Gubler H.V.et al. Biological effects of cyclosporein A: a new anti-lymphocyte agent. Agents Actions. 6:1976;468-475.
    • (1976) Agents Actions , vol.6 , pp. 468-475
    • Borel, J.F.1    Feurer, C.2    Gubler, H.V.3
  • 20
    • 17344373954 scopus 로고    scopus 로고
    • Successful mycophenolate mofetil treatment of glomerular disease
    • Briggs W.A., Choi M.J., Scheel P.J. Jr. Successful mycophenolate mofetil treatment of glomerular disease. Am. J. Kidney Dis. 31:1998;213-217.
    • (1998) Am. J. Kidney Dis. , vol.31 , pp. 213-217
    • Briggs, W.A.1    Choi, M.J.2    Scheel, P.j.jr.3
  • 21
    • 0014251127 scopus 로고
    • 51Cr-labelled allogeneic target cells in vitro; Inhibition by isoantibody and drugs
    • 51Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and drugs. J. Immunol. 14:1988;181-196.
    • (1988) J. Immunol. , vol.14 , pp. 181-196
    • Brunner, K.T.1    Mauel, J.2    Cerrotini, J.C.3    Chapuis, B.4
  • 23
    • 0027717956 scopus 로고
    • Characterization of human type I and type II IMP dehydrogenases
    • Carr S.F., Papp E., Wu J.C., Natsumeda Y. Characterization of human type I and type II IMP dehydrogenases. J. Biol. Chem. 268:1993;27286-272902.
    • (1993) J. Biol. Chem. , vol.268 , pp. 27286-272902
    • Carr, S.F.1    Papp, E.2    Wu, J.C.3    Natsumeda, Y.4
  • 24
    • 0028845643 scopus 로고
    • Inhibition of experimental autoimmune uveoretinitis by mycophenolate mofetil, an inhibitor of purine metabolism
    • Chanaud N.P. III, Vistica B.P., Eugui E.et al. Inhibition of experimental autoimmune uveoretinitis by mycophenolate mofetil, an inhibitor of purine metabolism. Exp. Eye Res. 61:1995;429-434.
    • (1995) Exp. Eye Res. , vol.61 , pp. 429-434
    • Chanaud N.P. III1    Vistica, B.P.2    Eugui, E.3
  • 25
    • 0027730750 scopus 로고
    • Brequinar sodium, mycophenolic acid, and cyclosporin A inhibit different stages of IL-4 or IL-3-induced human IgG4 and IgE production in vitro
    • Chang C.-C.J., Aversa G., Punnonen J., Yssel H., de Vries J. Brequinar sodium, mycophenolic acid, and cyclosporin A inhibit different stages of IL-4 or IL-3-induced human IgG4 and IgE production in vitro. Ann. N. Y. Acad. Sci. 696:1993;108-122.
    • (1993) Ann. N. Y. Acad. Sci. , vol.696 , pp. 108-122
    • Chang, C.-C.J.1    Aversa, G.2    Punnonen, J.3    Yssel, H.4    De Vries, J.5
  • 27
    • 0033567353 scopus 로고    scopus 로고
    • Mycophenolic acid increases apoptosis, lysosomes and lipid droplets in human lymphoid and monocytic cell lines
    • Cohn R.G., Mirkovich A., Dunlap B.et al. Mycophenolic acid increases apoptosis, lysosomes and lipid droplets in human lymphoid and monocytic cell lines. Transplantation. 68:1996;411-418.
    • (1996) Transplantation , vol.68 , pp. 411-418
    • Cohn, R.G.1    Mirkovich, A.2    Dunlap, B.3
  • 28
    • 0030944041 scopus 로고    scopus 로고
    • Mycophenolate mofetil limits renal damage and prolongs life in murine lupus autoimmune disease
    • Corna D., Morigi M., Facchinettiet al. Mycophenolate mofetil limits renal damage and prolongs life in murine lupus autoimmune disease. Kidney Int. 51:1997;1583-1589.
    • (1997) Kidney Int. , vol.51 , pp. 1583-1589
    • Corna, D.1    Morigi, M.2    Facchinettiet, al.3
  • 29
    • 0032570298 scopus 로고    scopus 로고
    • Mycophenolate mofetil: A promising new immunosuppressant that does not cause bone loss in the rat
    • Dissanayake I.R., Goodman G.R., Bowman A.R.et al. Mycophenolate mofetil: a promising new immunosuppressant that does not cause bone loss in the rat. Transplantation. 65:1998;275-278.
    • (1998) Transplantation , vol.65 , pp. 275-278
    • Dissanayake, I.R.1    Goodman, G.R.2    Bowman, A.R.3
  • 30
    • 0343482601 scopus 로고    scopus 로고
    • Rapamycin induces TGF-β production in lymphocytes
    • Dodge I.L., Li X.C., Ström T.B. Rapamycin induces TGF-β production in lymphocytes. Transplantation. 67:1999;S50.
    • (1999) Transplantation , vol.67 , pp. 50
    • Dodge, I.L.1    Li, X.C.2    Ström, T.B.3
  • 31
    • 0031693336 scopus 로고    scopus 로고
    • Treatment of relapsing idiopathic nodular panniculitis (Pfeiffer-Weber-Christian disease) with mycophenolate mofetil
    • Enk A.H., Knop J. Treatment of relapsing idiopathic nodular panniculitis (Pfeiffer-Weber-Christian disease) with mycophenolate mofetil. J. Am. Acad. Dermatol. 39:1998;508-509.
    • (1998) J. Am. Acad. Dermatol. , vol.39 , pp. 508-509
    • Enk, A.H.1    Knop, J.2
  • 32
    • 0344450757 scopus 로고    scopus 로고
    • Mycophenolate mofetil is effective in the treatment of pemphigus vulgaris
    • Enk A.H., Knop J. Mycophenolate mofetil is effective in the treatment of pemphigus vulgaris. Arch. Dermatol. 135:1999;54-56.
    • (1999) Arch. Dermatol. , vol.135 , pp. 54-56
    • Enk, A.H.1    Knop, J.2
  • 33
    • 0026034886 scopus 로고
    • Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: Role of deoxyguanosine nucleotide depletion
    • Eugui E.M., Almquist S., Muller C.D., Allison A.C. Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: role of deoxyguanosine nucleotide depletion. Scand. J. Immunol. 33:1991;161-173.
    • (1991) Scand. J. Immunol. , vol.33 , pp. 161-173
    • Eugui, E.M.1    Almquist, S.2    Muller, C.D.3    Allison, A.C.4
  • 34
    • 0026081633 scopus 로고
    • Lymphocyte-selective antiproliferative and immunosuppressive effects of mycophenolic acid in mice
    • Eugui E.M., Mirkovich A., Allison A.C. Lymphocyte-selective antiproliferative and immunosuppressive effects of mycophenolic acid in mice. Scand. J. Immunol. 33:1991;175-183.
    • (1991) Scand. J. Immunol. , vol.33 , pp. 175-183
    • Eugui, E.M.1    Mirkovich, A.2    Allison, A.C.3
  • 35
    • 85081191038 scopus 로고
    • Effect of mycophenolic acid on antibody titers and isotypes in mice vaccinated with influenza virus hemagglutinin
    • Eugui E.M., Nakano G.M., Byars N.E. Effect of mycophenolic acid on antibody titers and isotypes in mice vaccinated with influenza virus hemagglutinin. 9th Internat. Congr. Immunology, Abstracts 5073. 1995.
    • (1995) 9th Internat. Congr. Immunology, Abstracts 5073
    • Eugui, E.M.1    Nakano, G.M.2    Byars, N.E.3
  • 36
    • 0029585361 scopus 로고
    • Importance of ribonucleotide availability to proliferating T-lymphocytes from healthy humans. Disproportionate expansion of pyrimidine pools and contrasting effects of de novo synthesis inhibitors
    • Fairbanks L.D., Bofill M., Ruckemann K., Simmonds H.A. Importance of ribonucleotide availability to proliferating T-lymphocytes from healthy humans. Disproportionate expansion of pyrimidine pools and contrasting effects of de novo synthesis inhibitors. J. Biol. Chem. 270:1995;29682-29689.
    • (1995) J. Biol. Chem. , vol.270 , pp. 29682-29689
    • Fairbanks, L.D.1    Bofill, M.2    Ruckemann, K.3    Simmonds, H.A.4
  • 37
    • 0014546166 scopus 로고
    • The inhibition of nucleic acid synthesis by mycophenolic acid
    • Franklin T.J., Cook J.M. The inhibition of nucleic acid synthesis by mycophenolic acid. Biochem. J. 113:1969;515-524.
    • (1969) Biochem. J. , vol.113 , pp. 515-524
    • Franklin, T.J.1    Cook, J.M.2
  • 38
    • 0029550055 scopus 로고
    • Suppression by mycophenolate mofetil of the neointimal thickening caused by vascular injury in a rat arterial stenosis model
    • Fraser-Smith E.B., Rosette J.D., Schatzman R.C. Suppression by mycophenolate mofetil of the neointimal thickening caused by vascular injury in a rat arterial stenosis model. J. Pharmacol. Exp. Ther. 275:1995;1204-1208.
    • (1995) J. Pharmacol. Exp. Ther. , vol.275 , pp. 1204-1208
    • Fraser-Smith, E.B.1    Rosette, J.D.2    Schatzman, R.C.3
  • 39
    • 0031725546 scopus 로고    scopus 로고
    • Mycophenolate mofetil attenuates renal injury in the rat remnant kidney
    • Fujihara C.K., Malheiros D.M., Zatz R., Noronha I.D. Mycophenolate mofetil attenuates renal injury in the rat remnant kidney. Kidney Int. 45:1998;1510-1519.
    • (1998) Kidney Int. , vol.45 , pp. 1510-1519
    • Fujihara, C.K.1    Malheiros, D.M.2    Zatz, R.3    Noronha, I.D.4
  • 40
    • 0017653422 scopus 로고
    • Control of phosphoribosyl pyrophosphate synthesis in human lymphocytes
    • Garcia R.C., Leoni P., Allison A.C. Control of phosphoribosyl pyrophosphate synthesis in human lymphocytes. Biochem. Biophys. Res. Commun. 77:1977;1067-1073.
    • (1977) Biochem. Biophys. Res. Commun. , vol.77 , pp. 1067-1073
    • Garcia, R.C.1    Leoni, P.2    Allison, A.C.3
  • 42
    • 0015515283 scopus 로고
    • Adenosine deaminase deficiency in two patients with severely impaired cellular immunity
    • Giblett E.R., Anderson J.E., Cohen F., Meuwissen H.J. Adenosine deaminase deficiency in two patients with severely impaired cellular immunity. Lancet. II:1972;1067-1069.
    • (1972) Lancet , vol.2 , pp. 1067-1069
    • Giblett, E.R.1    Anderson, J.E.2    Cohen, F.3    Meuwissen, H.J.4
  • 43
    • 0031880581 scopus 로고    scopus 로고
    • Mycophenolate mofetil therapy for lupus nephritis refractory to intravenous cyclophosphamide
    • Glinklich D., Acharya A. Mycophenolate mofetil therapy for lupus nephritis refractory to intravenous cyclophosphamide. Am. J. Kidney Dis. 32:1998;318-322.
    • (1998) Am. J. Kidney Dis. , vol.32 , pp. 318-322
    • Glinklich, D.1    Acharya, A.2
  • 44
    • 0027156705 scopus 로고
    • Therapy of rheumatoid arthritis with mycophenolate mofetil
    • (Suppl.)
    • Goldblum R. Therapy of rheumatoid arthritis with mycophenolate mofetil. Clin. Exp. Rheumatol. 11:1993;S117-119. (Suppl.).
    • (1993) Clin. Exp. Rheumatol. , vol.11 , pp. 117-119
    • Goldblum, R.1
  • 45
    • 0030761958 scopus 로고    scopus 로고
    • Phenotype and localization of macrophages expressing inducible nitric oxide synthase in rat hepatic allograft rejection
    • Goto M., Yamaguchi Y., Ichiguchi O.et al. Phenotype and localization of macrophages expressing inducible nitric oxide synthase in rat hepatic allograft rejection. Transplantation. 64:1997;303-310.
    • (1997) Transplantation , vol.64 , pp. 303-310
    • Goto, M.1    Yamaguchi, Y.2    Ichiguchi, O.3
  • 47
    • 0017814565 scopus 로고
    • Extensive prolongation of rabbit kidney allograft survival after short-term cyclosporin A treatment
    • Green C.J., Allison A.C. Extensive prolongation of rabbit kidney allograft survival after short-term cyclosporin A treatment. Lancet. ii:1978;1182-1184.
    • (1978) Lancet , vol.2 , pp. 1182-1184
    • Green, C.J.1    Allison, A.C.2
  • 48
    • 0018770392 scopus 로고
    • Induction of specific tolerance in rabbits by kidney allografting and short period of cyclosporin A therapy
    • Green C.J., Allison A.C., Precious S. Induction of specific tolerance in rabbits by kidney allografting and short period of cyclosporin A therapy. Lancet. ii:1979;123-125.
    • (1979) Lancet , vol.2 , pp. 123-125
    • Green, C.J.1    Allison, A.C.2    Precious, S.3
  • 49
    • 0028909630 scopus 로고
    • Treatment with rapamycin and mycophenolic acid reduces arterial intimal thickening produced by mechanical injury and allows endothelial replacement
    • Gregory C.R., Huang X.et al. Treatment with rapamycin and mycophenolic acid reduces arterial intimal thickening produced by mechanical injury and allows endothelial replacement. Transplantation. 59:1995;655-661.
    • (1995) Transplantation , vol.59 , pp. 655-661
    • Gregory, C.R.1    Huang, X.2
  • 50
    • 0023762901 scopus 로고
    • Down regulation of cell adhesion molecules LFA-3 and ICAM-1 in Epstein-Barr virus-positive Burkitt's lymphoma underlies tumor cell escape from virus-specific T cell surveillance
    • Gregory C.D., Murray R.J., Edwards C.F., Rickinson A.D. Down regulation of cell adhesion molecules LFA-3 and ICAM-1 in Epstein-Barr virus-positive Burkitt's lymphoma underlies tumor cell escape from virus-specific T cell surveillance. J. Exp. Med. 167:1988;1811-1824.
    • (1988) J. Exp. Med. , vol.167 , pp. 1811-1824
    • Gregory, C.D.1    Murray, R.J.2    Edwards, C.F.3    Rickinson, A.D.4
  • 51
    • 0027529376 scopus 로고
    • Effects of treatment with cyclosporine, FK-506, rapamycin, mycophenolic acid, or dexoyspergualin on vascular muscle proliferation in vitro and in vivo
    • Gregory C.R., Pratt R.E., Huie P.et al. Effects of treatment with cyclosporine, FK-506, rapamycin, mycophenolic acid, or dexoyspergualin on vascular muscle proliferation in vitro and in vivo. Transplant Proc. 25:1993;770-771.
    • (1993) Transplant Proc. , vol.25 , pp. 770-771
    • Gregory, C.R.1    Pratt, R.E.2    Huie, P.3
  • 52
    • 0032998159 scopus 로고    scopus 로고
    • Mycophenolate mofetil: A new therapeutic option in the treatment of blistering autoimmune diseases
    • Grundmann-Kollman M., Korting H.C.et al. Mycophenolate mofetil: a new therapeutic option in the treatment of blistering autoimmune diseases. J. Am. Acad. Dermatol. 40:1999;957-960.
    • (1999) J. Am. Acad. Dermatol. , vol.40 , pp. 957-960
    • Grundmann-Kollman, M.1    Korting, H.C.2
  • 53
    • 0026578676 scopus 로고
    • Facilitation of tolerance induction in adult mice by RS-61443
    • Hao L., Calcinaro F., Gill R.G.et al. Facilitation of tolerance induction in adult mice by RS-61443. Transplantation. 53:1992;590-595.
    • (1992) Transplantation , vol.53 , pp. 590-595
    • Hao, L.1    Calcinaro, F.2    Gill, R.G.3
  • 54
    • 0027729166 scopus 로고
    • Mycophenolate mofetil can prevent the development of diabetes in BB rats
    • Hao L.M., Chan S.M., Lafferty K.J. Mycophenolate mofetil can prevent the development of diabetes in BB rats. Ann. N. Y. Acad. Sci. 696:1993;328-332.
    • (1993) Ann. N. Y. Acad. Sci. , vol.696 , pp. 328-332
    • Hao, L.M.1    Chan, S.M.2    Lafferty, K.J.3
  • 55
    • 0025321482 scopus 로고
    • RS-61443 allows islet allografting and specific tolerance induction in adult mice
    • Hao L., Lafferty K.J., Allison A.C., Eugui E.M. RS-61443 allows islet allografting and specific tolerance induction in adult mice. Transplant Proc. 22:1990;876-879.
    • (1990) Transplant Proc. , vol.22 , pp. 876-879
    • Hao, L.1    Lafferty, K.J.2    Allison, A.C.3    Eugui, E.M.4
  • 57
    • 0032913242 scopus 로고    scopus 로고
    • Mycophenolate mofetil: Therapeutic applications in kidney transplantation and immune-mediated renal disease
    • Hauser I.A., Bernd Sterzel R. Mycophenolate mofetil: therapeutic applications in kidney transplantation and immune-mediated renal disease. Curr. Opin. Nephrol. Hypertens. 8:1999;1-6.
    • (1999) Curr. Opin. Nephrol. Hypertens. , vol.8 , pp. 1-6
    • Hauser, I.A.1    Bernd Sterzel, R.2
  • 58
    • 0031752263 scopus 로고    scopus 로고
    • Successful treatment of a patient with severe refractory myasthenia gravis using mycophenolate mofetil
    • Hauser R.A., Malek A.R., Rosen R. Successful treatment of a patient with severe refractory myasthenia gravis using mycophenolate mofetil. Neurology. 51:1998;912-913.
    • (1998) Neurology , vol.51 , pp. 912-913
    • Hauser, R.A.1    Malek, A.R.2    Rosen, R.3
  • 59
    • 0030733294 scopus 로고    scopus 로고
    • Effect of mycophenolic acid on TNF alpha-induced expression of cell adhesion molecules in human venous endothelial cells in vitro
    • Hauser I.A., Johnson D.R., Thévenod F., Goppelt-Strübe M. Effect of mycophenolic acid on TNF alpha-induced expression of cell adhesion molecules in human venous endothelial cells in vitro. Br. J. Pharmacol. 122:1997a;1315-1322.
    • (1997) Br. J. Pharmacol. , vol.122 , pp. 1315-1322
    • Hauser, I.A.1    Johnson, D.R.2    Thévenod, F.3    Goppelt-Strübe, M.4
  • 60
    • 85081193616 scopus 로고    scopus 로고
    • Mycophenolate mofetil, but not cyclosporin A or FK506, inhibits rat mesangial cell proliferation in vitro
    • (Abstr)
    • Hauser I.A., Renders L., Merkel C., Goppelt-Struebe M. Mycophenolate mofetil, but not cyclosporin A or FK506, inhibits rat mesangial cell proliferation in vitro. J. Am. Soc. Nephrol. 9:1997b;496A. (Abstr).
    • (1997) J. Am. Soc. Nephrol. , vol.9
    • Hauser, I.A.1    Renders, L.2    Merkel, C.3    Goppelt-Struebe, M.4
  • 62
    • 0029990776 scopus 로고    scopus 로고
    • Mycophenolate mofetil inhibits lymphocyte binding and the upregulation of adhesion molecules in acute rejection of rat kidney allografts
    • Heemann U., Azuma H., Hamar P.et al. Mycophenolate mofetil inhibits lymphocyte binding and the upregulation of adhesion molecules in acute rejection of rat kidney allografts. Transplant. Immunol. 4:1996;64-67.
    • (1996) Transplant. Immunol. , vol.4 , pp. 64-67
    • Heemann, U.1    Azuma, H.2    Hamar, P.3
  • 63
    • 0001318799 scopus 로고    scopus 로고
    • MMF reduces proteinuria in passive Heymann nephritis
    • (Abstr)
    • Heering P., Heise G., Hess A. MMF reduces proteinuria in passive Heymann nephritis. J. Am. Soc. Nephrol. 9:1998;456A-457A. (Abstr).
    • (1998) J. Am. Soc. Nephrol. , vol.9
    • Heering, P.1    Heise, G.2    Hess, A.3
  • 64
    • 0345627998 scopus 로고    scopus 로고
    • Mycophenolate mofetil and cyclosporin treatment for recalcitrant pyoderma gangrenosum
    • Hohenleutner U., Mohr V.D., Michel S., Landthaler M. Mycophenolate mofetil and cyclosporin treatment for recalcitrant pyoderma gangrenosum. Lancet. 350:1997;1748.
    • (1997) Lancet , vol.350 , pp. 1748
    • Hohenleutner, U.1    Mohr, V.D.2    Michel, S.3    Landthaler, M.4
  • 65
    • 0016741871 scopus 로고
    • Rapid increase of phosphoribosyl pyrophosphate concentration after mitogenic stimulation of lymphocytes
    • Hovi T., Allison A.C., Allsop J. Rapid increase of phosphoribosyl pyrophosphate concentration after mitogenic stimulation of lymphocytes. FEBS Lett. 55:1975;291-293.
    • (1975) FEBS Lett. , vol.55 , pp. 291-293
    • Hovi, T.1    Allison, A.C.2    Allsop, J.3
  • 67
    • 85081192942 scopus 로고    scopus 로고
    • Effect of mycophenolate mofetil on anti-Thy-1 mesangial proliferative glomerulonephritis
    • Huang Q.-Y., Ye W.-L., Zheng F.-L. Effect of mycophenolate mofetil on anti-Thy-1 mesangial proliferative glomerulonephritis. J. Am. Soc. Nephrol. 9:1998;496A.
    • (1998) J. Am. Soc. Nephrol. , vol.9
    • Huang, Q.-Y.1    Ye, W.-L.2    Zheng, F.-L.3
  • 68
    • 0023028511 scopus 로고
    • IMP dehydrogenase from the intracellular parasitic protozoan Eimeria tenella and its inhibition by mycophenolic acid
    • Hupe D.J., Azzolina B.A., Behrens N.D. IMP dehydrogenase from the intracellular parasitic protozoan Eimeria tenella and its inhibition by mycophenolic acid. J. Biol. Chem. 261:1986;8363-8369.
    • (1986) J. Biol. Chem. , vol.261 , pp. 8363-8369
    • Hupe, D.J.1    Azzolina, B.A.2    Behrens, N.D.3
  • 69
    • 0029116425 scopus 로고
    • Polymerase substrate depletion: A novel strategy for inhibiting the replication of the human immunodeficiency virus
    • Ichimura H., Levy J.A. Polymerase substrate depletion: a novel strategy for inhibiting the replication of the human immunodeficiency virus. Virology. 211:1995;554-560.
    • (1995) Virology , vol.211 , pp. 554-560
    • Ichimura, H.1    Levy, J.A.2
  • 70
    • 0026579147 scopus 로고
    • Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1
    • Isobe M., Yagita H., Okumura K., Ihara A. Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1. Science. 255:1992;1125-1127.
    • (1992) Science , vol.255 , pp. 1125-1127
    • Isobe, M.1    Yagita, H.2    Okumura, K.3    Ihara, A.4
  • 71
    • 0017687199 scopus 로고
    • Partial purification, properties and regulation of inosine 5′-phosphate dehydrogenase in normal and malignant rat tissues
    • Jackson R.C., Morris H.P., Weber G. Partial purification, properties and regulation of inosine 5′-phosphate dehydrogenase in normal and malignant rat tissues. Biochem. J. 166:1977;1-10.
    • (1977) Biochem. J. , vol.166 , pp. 1-10
    • Jackson, R.C.1    Morris, H.P.2    Weber, G.3
  • 72
    • 0006986048 scopus 로고    scopus 로고
    • A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation
    • Keown P.A.et al. A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation. Transplantation. 61:1996;1029-1037.
    • (1996) Transplantation , vol.61 , pp. 1029-1037
    • Keown, P.A.1
  • 73
    • 0343482511 scopus 로고    scopus 로고
    • TGF-beta provides the rationale for the synergistic immunosuppression with rapamycin (RAPA), cyclosporine (CsA) and tacrolimus (TAC) calcineurin inhibitors sparing immunosuppression protocol
    • Khanna A. TGF-beta provides the rationale for the synergistic immunosuppression with rapamycin (RAPA), cyclosporine (CsA) and tacrolimus (TAC) calcineurin inhibitors sparing immunosuppression protocol. Transplantation. 67:1999;S58.
    • (1999) Transplantation , vol.67 , pp. 58
    • Khanna, A.1
  • 74
    • 0032931313 scopus 로고    scopus 로고
    • Attenuated acute cardiac rejection in NOS2-/- recipients
    • Koglin J., Granville D.J., Glysing-Jensen T.et al. Attenuated acute cardiac rejection in NOS2-/- recipients. Circulation. 99:1999;836-842.
    • (1999) Circulation , vol.99 , pp. 836-842
    • Koglin, J.1    Granville, D.J.2    Glysing-Jensen, T.3
  • 75
    • 0031768307 scopus 로고    scopus 로고
    • NOS2 mediates opposing effects in models of acute and chronic cardiac rejection: Insights from NOS2-knockout mice
    • Koglin J., Glysing-Jensen T., Mudgett S.S., Russell M.E. NOS2 mediates opposing effects in models of acute and chronic cardiac rejection: insights from NOS2-knockout mice. Am. J. Pathol. 153:1998;1371-1376.
    • (1998) Am. J. Pathol. , vol.153 , pp. 1371-1376
    • Koglin, J.1    Glysing-Jensen, T.2    Mudgett, S.S.3    Russell, M.E.4
  • 76
    • 0025961794 scopus 로고
    • Expression of IMP dehydrogenase types I and II in Escherichia coli and distribution in normal human lymphocytes and leukemic cell lines
    • Konno Y., Natsumeda Y., Nagai M.et al. Expression of IMP dehydrogenase types I and II in Escherichia coli and distribution in normal human lymphocytes and leukemic cell lines. J. Biol. Chem. 266:1991;506-509.
    • (1991) J. Biol. Chem. , vol.266 , pp. 506-509
    • Konno, Y.1    Natsumeda, Y.2    Nagai, M.3
  • 77
    • 0004004917 scopus 로고
    • Structure of glycoproteins and their oligosaccharide units
    • W.J. Lennarz. New York: Plenum
    • Kornfeld R., Kornfeld S. Structure of glycoproteins and their oligosaccharide units. Lennarz W.J. Biochemistry Glycoproteins and Proteoglycans. 1980;1-137 Plenum, New York.
    • (1980) Biochemistry Glycoproteins and Proteoglycans , pp. 1-137
    • Kornfeld, R.1    Kornfeld, S.2
  • 78
    • 0033506431 scopus 로고    scopus 로고
    • Mycophenolate mofetil. A useful immunosuppressive in inflammatory eye disease
    • Larkin G., Lightman S. Mycophenolate mofetil. A useful immunosuppressive in inflammatory eye disease. Ophthomology. 106:1999;370-374.
    • (1999) Ophthomology , vol.106 , pp. 370-374
    • Larkin, G.1    Lightman, S.2
  • 79
    • 0026445723 scopus 로고
    • Selectins: Interpreters of cell-specific carbohydrate information during inflammation
    • Laski L.A. Selectins: interpreters of cell-specific carbohydrate information during inflammation. Science. 258:1992;964-969.
    • (1992) Science , vol.258 , pp. 964-969
    • Laski, L.A.1
  • 80
    • 0030071890 scopus 로고    scopus 로고
    • Mycophenolic acid suppresses protein N-linked glycosylation in human monocytes and their adhesion to endothelial cells and some substrates
    • Laurent A.F., Dumont S., Poindron P., Muller C.D. Mycophenolic acid suppresses protein N-linked glycosylation in human monocytes and their adhesion to endothelial cells and some substrates. Exp. Hematol. 24:1996;59-67.
    • (1996) Exp. Hematol. , vol.24 , pp. 59-67
    • Laurent, A.F.1    Dumont, S.2    Poindron, P.3    Muller, C.D.4
  • 81
    • 0025281073 scopus 로고
    • Bioavailability improvement of mycophenolic acid through amino ester derivitization
    • Lee W.A., Gu L., Miksztal A.R., Chu N.et al. Bioavailability improvement of mycophenolic acid through amino ester derivitization. Pharm. Res. 7:1990;161-166.
    • (1990) Pharm. Res. , vol.7 , pp. 161-166
    • Lee, W.A.1    Gu, L.2    Miksztal, A.R.3    Chu, N.4
  • 82
    • 0018226516 scopus 로고
    • Effects of cyclosporin A on human lymphocytes in culture
    • Leoni P., Garcia R.C., Allison A.C. Effects of cyclosporin A on human lymphocytes in culture. J. Lab. Clin. Immunol. 1:1978;67-75.
    • (1978) J. Lab. Clin. Immunol. , vol.1 , pp. 67-75
    • Leoni, P.1    Garcia, R.C.2    Allison, A.C.3
  • 83
    • 0000084110 scopus 로고    scopus 로고
    • Mycophenolate mofetil showed inhibitory effect on VCAM expression during successful treatment of diffuse proliferative lupus nephritis (SLE-DPGN) with vascular lesions
    • Li L.-S., Liu Z.-H., Hong Z., Hu W.-X. Mycophenolate mofetil showed inhibitory effect on VCAM expression during successful treatment of diffuse proliferative lupus nephritis (SLE-DPGN) with vascular lesions. J. Am. Soc. Nephrol. 9:1998;153A.
    • (1998) J. Am. Soc. Nephrol. , vol.9
    • Li, L.-S.1    Liu, Z.-H.2    Hong, Z.3    Hu, W.-X.4
  • 84
    • 0032841022 scopus 로고    scopus 로고
    • Abacavir and mycophenolic acid, an inhibitor of inosine monophosphate dehydrogenase, have profound and synergistic anti-HIV activity
    • (in press)
    • Margolis D., Heredia A., Gaywee J. Abacavir and mycophenolic acid, an inhibitor of inosine monophosphate dehydrogenase, have profound and synergistic anti-HIV activity. J. AIDS. 1999;. (in press).
    • (1999) J. AIDS
    • Margolis, D.1    Heredia, A.2    Gaywee, J.3
  • 85
    • 85081194144 scopus 로고    scopus 로고
    • Mycophenolate mofetil (MMF) prevents acute rejection and assures high one-year graft survival also in the case of delayed graft function
    • (Abstr)
    • Maurizio S., Bertoni E., Rosati A.et al. Mycophenolate mofetil (MMF) prevents acute rejection and assures high one-year graft survival also in the case of delayed graft function. J. Am. Soc. Nephrol. 9:1998;696A. (Abstr).
    • (1998) J. Am. Soc. Nephrol. , vol.9
    • Maurizio, S.1    Bertoni, E.2    Rosati, A.3
  • 86
    • 0031796741 scopus 로고    scopus 로고
    • Mycophenolate mofetil suppresses autoimmunity and mortality in the female (NZB×NZW)F1 mouse model of systemic lupus erythematosis
    • McMurray R.W., Ellbourne K., Lagoo A.et al. Mycophenolate mofetil suppresses autoimmunity and mortality in the female (NZB×NZW)F1 mouse model of systemic lupus erythematosis. J. Rheumatol. 25:1998;2364-2370.
    • (1998) J. Rheumatol. , vol.25 , pp. 2364-2370
    • McMurray, R.W.1    Ellbourne, K.2    Lagoo, A.3
  • 87
    • 85081194585 scopus 로고
    • Prevention of murine graft-versus-host disease (GVHD) by mycophenolate mofetil
    • Mirkovich A., Eugui E.M. Prevention of murine graft-versus-host disease (GVHD) by mycophenolate mofetil. 9th Internat. Congr. Immunol. (Abstr). 1995;2523.
    • (1995) 9th Internat. Congr. Immunol. (Abstr) , pp. 2523
    • Mirkovich, A.1    Eugui, E.M.2
  • 88
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology and pharmacology
    • Moncada S., Palmer R.M.J., Higgs E.A. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev. 43:1991;109-142.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 89
    • 0025087579 scopus 로고
    • Mycophenolic acid morpholinoethylester (RS-61443) is a new immunosuppressant that prevents and halts heart allograft rejection by selective inhibition of T and B cell purine synthesis
    • Morris R.E., Hoyt E.G., Murphy M.P., Eugui E.M., Allison A.C. Mycophenolic acid morpholinoethylester (RS-61443) is a new immunosuppressant that prevents and halts heart allograft rejection by selective inhibition of T and B cell purine synthesis. Transplant. Proc. 22:1990;1659-1662.
    • (1990) Transplant. Proc. , vol.22 , pp. 1659-1662
    • Morris, R.E.1    Hoyt, E.G.2    Murphy, M.P.3    Eugui, E.M.4    Allison, A.C.5
  • 90
    • 0025875138 scopus 로고
    • Immunosuppressive effects of the morpholinoethyl ester of mycophenolic acid (RS-61443) in rat and nonhuman primate recipients of heart allografts
    • Morris R.E., Wang J., Blum J.R.et al. Immunosuppressive effects of the morpholinoethyl ester of mycophenolic acid (RS-61443) in rat and nonhuman primate recipients of heart allografts. Transplant. Proc. 23(Suppl. 2):1991;19-25.
    • (1991) Transplant. Proc. , vol.23 , Issue.SUPPL. 2 , pp. 19-25
    • Morris, R.E.1    Wang, J.2    Blum, J.R.3
  • 91
    • 0032086655 scopus 로고    scopus 로고
    • Effect of mycophenolate mofetil on the in vivo infiltration of lymphocytes in the rat remnant kidney
    • Mueller V., Hamar P., Szabo A.et al. Effect of mycophenolate mofetil on the in vivo infiltration of lymphocytes in the rat remnant kidney. Transplant. Proc. 30:1998;982.
    • (1998) Transplant. Proc. , vol.30 , pp. 982
    • Mueller, V.1    Hamar, P.2    Szabo, A.3
  • 92
    • 0026635981 scopus 로고
    • Mycophenolic acid inhibits the degranulation of rat peritoneal mast cells
    • Mulkins M.A., Ng M., Lewis R.G. Mycophenolic acid inhibits the degranulation of rat peritoneal mast cells. Cell. Immunol. 141:1992;508-517.
    • (1992) Cell. Immunol. , vol.141 , pp. 508-517
    • Mulkins, M.A.1    Ng, M.2    Lewis, R.G.3
  • 93
    • 0343918280 scopus 로고    scopus 로고
    • Mycophenolate mofetil therapy in patients with cyclophosphamide-(CyP) resistant or relapsing diffuse proliferative lupus nephritis (SLE-DPGN)
    • Nachman P.H., Dooley M.A., Hogan S.L.et al. Mycophenolate mofetil therapy in patients with cyclophosphamide-(CyP) resistant or relapsing diffuse proliferative lupus nephritis (SLE-DPGN). J. Am. Soc. Nephrol. 9:1997;94A.
    • (1997) J. Am. Soc. Nephrol. , vol.9
    • Nachman, P.H.1    Dooley, M.A.2    Hogan, S.L.3
  • 94
    • 0030461540 scopus 로고    scopus 로고
    • Sequential cytokine expression in renal allografts in rats immunosuppressed with maintenance cyclosporine or mycophenolate mofetil
    • Nadeau K.C., Azuma H., Tilney N.L. Sequential cytokine expression in renal allografts in rats immunosuppressed with maintenance cyclosporine or mycophenolate mofetil. Transplantation. 62:1996;1363-1366.
    • (1996) Transplantation , vol.62 , pp. 1363-1366
    • Nadeau, K.C.1    Azuma, H.2    Tilney, N.L.3
  • 95
    • 0026546968 scopus 로고
    • Proliferation-linked regulation of the type II IMP dehydrogenase gene in human normal lymphocytes and HL-60 leukemic cells
    • Nagai M., Natsumeda Y., Weber G. Proliferation-linked regulation of the type II IMP dehydrogenase gene in human normal lymphocytes and HL-60 leukemic cells. Cancer Res. 52:1992;258-261.
    • (1992) Cancer Res. , vol.52 , pp. 258-261
    • Nagai, M.1    Natsumeda, Y.2    Weber, G.3
  • 96
    • 0027179319 scopus 로고
    • Effect of mycophenolate mofetil (RS-61443) on cytokine production: Inhibition of superantigen-induced cytokines
    • Nagy S.E., Andersson J.P., Andersson U.G. Effect of mycophenolate mofetil (RS-61443) on cytokine production: inhibition of superantigen-induced cytokines. Immunopharmacology. 26:1993;11-20.
    • (1993) Immunopharmacology , vol.26 , pp. 11-20
    • Nagy, S.E.1    Andersson, J.P.2    Andersson, U.G.3
  • 97
    • 0025232817 scopus 로고
    • Two distinct cDNAs for human IMP dehydrogenase
    • Natsumeda Y., Ohno S., Kawasaki H.et al. Two distinct cDNAs for human IMP dehydrogenase. J. Biol. Chem. 265:1990;5292-5295.
    • (1990) J. Biol. Chem. , vol.265 , pp. 5292-5295
    • Natsumeda, Y.1    Ohno, S.2    Kawasaki, H.3
  • 98
    • 0000737487 scopus 로고    scopus 로고
    • The role of mycophenolate mofetil in the management of refractory inflammatory bowel disease (IBD)
    • Nehme O.S., Overley C.A., O'Brien J.J. The role of mycophenolate mofetil in the management of refractory inflammatory bowel disease (IBD). Gastroenterology. 114(4 (Pt. 2)):1998;A1049.
    • (1998) Gastroenterology , vol.114 , Issue.4 PT. 2 , pp. 1049
    • Nehme, O.S.1    Overley, C.A.2    O'Brien, J.J.3
  • 99
    • 85029242571 scopus 로고    scopus 로고
    • Randomized trial of mycophenolate mofetil versus azathioprine for treatment of chronic active Crohn's disease
    • Neurath M.F., Wanitschke R., Peters M.et al. Randomized trial of mycophenolate mofetil versus azathioprine for treatment of chronic active Crohn's disease. Gastroenterology. 114(4 (Pt. 2)):1998;A1050.
    • (1998) Gastroenterology , vol.114 , Issue.4 PT. 2 , pp. 1050
    • Neurath, M.F.1    Wanitschke, R.2    Peters, M.3
  • 100
    • 0031952851 scopus 로고    scopus 로고
    • The novel immunosuppressive agent mycophenolate mofetil markedly potentiates the antiherpesvirus activities of acyclovir, ganciclovir, and penciclovir in vitro and in vivo
    • Neyts J., Andrei G., De Clercq E. The novel immunosuppressive agent mycophenolate mofetil markedly potentiates the antiherpesvirus activities of acyclovir, ganciclovir, and penciclovir in vitro and in vivo. Antimicro. Agents Chemother. 42:1998;216-222.
    • (1998) Antimicro. Agents Chemother. , vol.42 , pp. 216-222
    • Neyts, J.1    Andrei, G.2    De Clercq, E.3
  • 101
    • 0031758701 scopus 로고    scopus 로고
    • The antiherpesvirus activity of H2G is markedly enhanced by the novel immunosuppressive agent mycophenolate mofetil
    • Neyts J., Andrei G., De Clercq E. The antiherpesvirus activity of H2G is markedly enhanced by the novel immunosuppressive agent mycophenolate mofetil. Antimicro. Agents Chemother. 42:1998;3285-3289.
    • (1998) Antimicro. Agents Chemother. , vol.42 , pp. 3285-3289
    • Neyts, J.1    Andrei, G.2    De Clercq, E.3
  • 102
    • 0029888393 scopus 로고    scopus 로고
    • Use of the yellow fever virus vaccine strain 17D for the study of strategies for the treatment of yellow fever virus infection
    • Neyts J., Meerbach A., McKenna P., De Chercq E. Use of the yellow fever virus vaccine strain 17D for the study of strategies for the treatment of yellow fever virus infection. Antiviral Res. 30:1996;125-132.
    • (1996) Antiviral Res. , vol.30 , pp. 125-132
    • Neyts, J.1    Meerbach, A.2    McKenna, P.3    De Chercq, E.4
  • 103
    • 0000685778 scopus 로고    scopus 로고
    • Enhanced interstitial expression of angiotensin II and TGF-β In the renal ablation model: Effect of mycophenolate mofetil
    • (Abstr)
    • Noronha I.L., Fujihara C.K., Oliviera I.B., Leitao T.G., Zatz R. Enhanced interstitial expression of angiotensin II and TGF-β in the renal ablation model: effect of mycophenolate mofetil. J. Am. Soc. Nephrol. 9:1998;618A. (Abstr).
    • (1998) J. Am. Soc. Nephrol. , vol.9
    • Noronha, I.L.1    Fujihara, C.K.2    Oliviera, I.B.3    Leitao, T.G.4    Zatz, R.5
  • 104
    • 0031665851 scopus 로고    scopus 로고
    • Successful therapy for bullous pemphigoid with mycophenolate mofetil
    • Nousari H.C., Griffin W.A., Anhalt G.J. Successful therapy for bullous pemphigoid with mycophenolate mofetil. J. Am. Acad. Dermatol. 39:1998a;497-498.
    • (1998) J. Am. Acad. Dermatol. , vol.39 , pp. 497-498
    • Nousari, H.C.1    Griffin, W.A.2    Anhalt, G.J.3
  • 105
    • 0032417023 scopus 로고    scopus 로고
    • The effectiveness of mycophenolate mofetil in refractory pyoderma gangrenosum
    • Nousari H.C., Lynch W., Anhalt G.J., Petri M. The effectiveness of mycophenolate mofetil in refractory pyoderma gangrenosum. Arch. Dermatol. 134:1998;1509-1511.
    • (1998) Arch. Dermatol. , vol.134 , pp. 1509-1511
    • Nousari, H.C.1    Lynch, W.2    Anhalt, G.J.3    Petri, M.4
  • 106
    • 0343472033 scopus 로고    scopus 로고
    • Mycophenolate mofetil for systemic vasculitis and IgA nephropathy
    • Nowack R., Birch R., Van de Woude F.J. Mycophenolate mofetil for systemic vasculitis and IgA nephropathy. Lancet. 349:1997;774.
    • (1997) Lancet , vol.349 , pp. 774
    • Nowack, R.1    Birch, R.2    Van De Woude, F.J.3
  • 109
    • 0028032807 scopus 로고
    • Inhibition of chronic vascular rejection in primate cardiac xenografts using mycophenolate mofetil
    • O'Hair D.P., McManus R.P., Komorowski R. Inhibition of chronic vascular rejection in primate cardiac xenografts using mycophenolate mofetil. Ann. Thorac. Surg. 58:1994;1311-1315.
    • (1994) Ann. Thorac. Surg. , vol.58 , pp. 1311-1315
    • O'Hair, D.P.1    McManus, R.P.2    Komorowski, R.3
  • 110
    • 0030944969 scopus 로고    scopus 로고
    • Novel anti-Pneumocystis carinii effects of the immunosuppressant mycophenolate mofetil in contrast to the provocative effects of tacrolimus, sirolimus and dexamethasone
    • Ozchgfhj H.S., Hughes W.T. Novel anti-Pneumocystis carinii effects of the immunosuppressant mycophenolate mofetil in contrast to the provocative effects of tacrolimus, sirolimus and dexamethasone. J. Infect. Dis. 175:1997;901-904.
    • (1997) J. Infect. Dis. , vol.175 , pp. 901-904
    • Ozchgfhj, H.S.1    Hughes, W.T.2
  • 111
    • 0033058907 scopus 로고    scopus 로고
    • Decrease of apoptosis rate in patients treated with mycophenolate mofetil
    • Pardo-Mindán F.J., Errasti P., Panizo A.et al. Decrease of apoptosis rate in patients treated with mycophenolate mofetil. Nephron. 82:1999;232-237.
    • (1999) Nephron , vol.82 , pp. 232-237
    • Pardo-Mindán, F.J.1    Errasti, P.2    Panizo, A.3
  • 112
    • 85081191127 scopus 로고    scopus 로고
    • Donor pretreatment with mycophenolate mofetil protects against ischemia-reperfusion injury
    • Paul L.C., Muzaffar S., Valentin J.-F. Donor pretreatment with mycophenolate mofetil protects against ischemia-reperfusion injury. Transplantation. 65:1998;1193-1195.
    • (1998) Transplantation , vol.65 , pp. 1193-1195
    • Paul, L.C.1    Muzaffar, S.2    Valentin, J.-F.3
  • 113
    • 0029858088 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibition is associated with decreased survival of cardiac allografts in the rat
    • Paul L.C., Myllärniemi M., Muzaffar S., Benediktsson H. Nitric oxide synthase inhibition is associated with decreased survival of cardiac allografts in the rat. Transplantation. 65:1996;1193-1195.
    • (1996) Transplantation , vol.65 , pp. 1193-1195
    • Paul, L.C.1    Myllärniemi, M.2    Muzaffar, S.3    Benediktsson, H.4
  • 114
    • 0031725135 scopus 로고    scopus 로고
    • Mycophenolate mofetil prevents the induction of active Heymann nephritis: Association with Th2 cytokine inhibition
    • Penny M.J., Boyd R.A., Hall B.M. Mycophenolate mofetil prevents the induction of active Heymann nephritis: association with Th2 cytokine inhibition. J. Am. Soc. Nephrol. 9:1998;2272-2282.
    • (1998) J. Am. Soc. Nephrol. , vol.9 , pp. 2272-2282
    • Penny, M.J.1    Boyd, R.A.2    Hall, B.M.3
  • 115
    • 0019970608 scopus 로고
    • Effects of adenosine and deoxyadenosine on PHA stimulation of lymphocytes of man, horse and pig
    • Peters G.J., Oosterhof A., Verkamp J.H. Effects of adenosine and deoxyadenosine on PHA stimulation of lymphocytes of man, horse and pig. Int. J. Biochem. 14:1982;377-385.
    • (1982) Int. J. Biochem. , vol.14 , pp. 377-385
    • Peters, G.J.1    Oosterhof, A.2    Verkamp, J.H.3
  • 116
    • 0031936145 scopus 로고    scopus 로고
    • Dyshidrotic eczema treated with mycophenolate mofetil
    • Pickenacker A., Luger T.A., Schwarz T. Dyshidrotic eczema treated with mycophenolate mofetil. Arch. Dermatol. 134:1998;378-379.
    • (1998) Arch. Dermatol. , vol.134 , pp. 378-379
    • Pickenacker, A.1    Luger, T.A.2    Schwarz, T.3
  • 117
    • 0026003086 scopus 로고
    • RS-61443 for reversal of acute rejection in canine renal allografts
    • Platz K.P., Eckhoff D., Bechstein W.O.et al. RS-61443 for reversal of acute rejection in canine renal allografts. Surgery. 110:1991;736-741.
    • (1991) Surgery , vol.110 , pp. 736-741
    • Platz, K.P.1    Eckhoff, D.2    Bechstein, W.O.3
  • 118
    • 0031833485 scopus 로고    scopus 로고
    • Indications for mycophenolate mofetil therapy in hepatitis C patients undergoing liver transplantation
    • Platz K.P., Mueller A.R., Willimeki C.et al. Indications for mycophenolate mofetil therapy in hepatitis C patients undergoing liver transplantation. Transplant. Proc. 30:1998;1468-1469.
    • (1998) Transplant. Proc. , vol.30 , pp. 1468-1469
    • Platz, K.P.1    Mueller, A.R.2    Willimeki, C.3
  • 119
  • 120
    • 0029609949 scopus 로고
    • Mycophenolate mofetil (MMF, RS-61443) inhibits proliferation of rat aortic allografts
    • Räisänen-Sokolowski A., Vuoristo P.et al. Mycophenolate mofetil (MMF, RS-61443) inhibits proliferation of rat aortic allografts. Transplant. Immunol. 3:1995;342-351.
    • (1995) Transplant. Immunol. , vol.3 , pp. 342-351
    • Räisänen-Sokolowski, A.1    Vuoristo, P.2
  • 121
    • 0032407223 scopus 로고    scopus 로고
    • Mycophenolate mofetil in ocular immunological disorders. A survey of the literature with 3 case reports
    • Reis A., Reinhard T., Sundmacher R.et al. Mycophenolate mofetil in ocular immunological disorders. A survey of the literature with 3 case reports. Klin. Monatsbl. Augenheilkd. 213:1998;257-261.
    • (1998) Klin. Monatsbl. Augenheilkd. , vol.213 , pp. 257-261
    • Reis, A.1    Reinhard, T.2    Sundmacher, R.3
  • 122
    • 0023578993 scopus 로고
    • Failure of dideoxynucleosides to inhibit HIV replication in cultured human macrophages
    • Richman D.D., Kornbluth R.S., Carson P.A. Failure of dideoxynucleosides to inhibit HIV replication in cultured human macrophages. J. Exp. Med. 166:1987;1144-1149.
    • (1987) J. Exp. Med. , vol.166 , pp. 1144-1149
    • Richman, D.D.1    Kornbluth, R.S.2    Carson, P.A.3
  • 123
    • 0011373544 scopus 로고    scopus 로고
    • Mycophenolate mofetil prevents the progressive renal failure induced by 5/6 renal ablation in rats
    • Romero F., Rodriguez-Iturbe B., Parra G.et al. Mycophenolate mofetil prevents the progressive renal failure induced by 5/6 renal ablation in rats. Kidney Int. 55:1999;945-955.
    • (1999) Kidney Int. , vol.55 , pp. 945-955
    • Romero, F.1    Rodriguez-Iturbe, B.2    Parra, G.3
  • 124
    • 0026748867 scopus 로고
    • Cellular basis of skin graft rejection: An in vivo model of immune-mediated tissue destruction
    • Rosenberg A.S., Singer A. Cellular basis of skin graft rejection: an in vivo model of immune-mediated tissue destruction. Annu. Rev. Immunol. 10:1992;333-358.
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 333-358
    • Rosenberg, A.S.1    Singer, A.2
  • 125
    • 0000891538 scopus 로고    scopus 로고
    • CellCept (mycophenolate mofetil-MMF), a new treatment for RA: A 12-week, double-blind, randomized, placebo-controlled withdrawal trial
    • Schiff M.H., Leishman B. CellCept (mycophenolate mofetil-MMF), a new treatment for RA: a 12-week, double-blind, randomized, placebo-controlled withdrawal trial. Arthritis Rheum. 41(Suppl. 9):1998;S364.
    • (1998) Arthritis Rheum. , vol.41 , Issue.SUPPL. 9 , pp. 364
    • Schiff, M.H.1    Leishman, B.2
  • 126
    • 0028889795 scopus 로고
    • Mycophenolic acid, an inhibitor of IMP dehydrogenase that is also an immunosuppressive agent, suppresses the cytokine-induced nitric oxide production in mouse and rat vascular endothelial cells
    • Senda M., DeLustro B., Eugui E., Natsumeda Y. Mycophenolic acid, an inhibitor of IMP dehydrogenase that is also an immunosuppressive agent, suppresses the cytokine-induced nitric oxide production in mouse and rat vascular endothelial cells. Transplantation. 60:1995;1143-1148.
    • (1995) Transplantation , vol.60 , pp. 1143-1148
    • Senda, M.1    Delustro, B.2    Eugui, E.3    Natsumeda, Y.4
  • 127
    • 0026661404 scopus 로고
    • Small bowel transplantation in rats using RS-61443: Effect on GVHD and rejections
    • Shaffer D., Blakely M.L., Gottschalk R., Monaco A.P. Small bowel transplantation in rats using RS-61443: effect on GVHD and rejections. Transplant. Proc. 24:1992;1159-1160.
    • (1992) Transplant. Proc. , vol.24 , pp. 1159-1160
    • Shaffer, D.1    Blakely, M.L.2    Gottschalk, R.3    Monaco, A.P.4
  • 128
    • 0027469016 scopus 로고
    • Prevention of graft-versus-host disease by RS-61443 in two different rodent models
    • Shaffer D., Muanza T., Blakely M.L.et al. Prevention of graft-versus-host disease by RS-61443 in two different rodent models. Transplantation. 55:1993;221-223.
    • (1993) Transplantation , vol.55 , pp. 221-223
    • Shaffer, D.1    Muanza, T.2    Blakely, M.L.3
  • 129
    • 0030727904 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase suppresses the development of allograft arteriosclerosis
    • Shears L.L., Kawaharada N., Tzeng E.et al. Inducible nitric oxide synthase suppresses the development of allograft arteriosclerosis. J. Clin. Invest. 100:1997;2035-2042.
    • (1997) J. Clin. Invest. , vol.100 , pp. 2035-2042
    • Shears, L.L.1    Kawaharada, N.2    Tzeng, E.3
  • 130
    • 0028136980 scopus 로고
    • Effect of topical preparation of mycophenolic acid on experimental allergic contact dermatitis of guinea-pigs induced by dinitrofluorobenzene
    • Shoji Y. Effect of topical preparation of mycophenolic acid on experimental allergic contact dermatitis of guinea-pigs induced by dinitrofluorobenzene. J. Pharm. Pharmacol. 46:1994;643-646.
    • (1994) J. Pharm. Pharmacol. , vol.46 , pp. 643-646
    • Shoji, Y.1
  • 131
    • 0034121721 scopus 로고    scopus 로고
    • The structure of inosine monophosphate dehydrogenase and the design of novel inhibitors
    • Sintchak M.D., Nimmesgern E. The structure of inosine monophosphate dehydrogenase and the design of novel inhibitors. Immunopharmacology. 47:2000;163-184.
    • (2000) Immunopharmacology , vol.47 , pp. 163-184
    • Sintchak, M.D.1    Nimmesgern, E.2
  • 132
    • 0027419734 scopus 로고
    • Effects of immunosuppressive therapy on the rat aortic allograft model
    • Steele D.M., Hullett D.A., Bechstein W.O.et al. Effects of immunosuppressive therapy on the rat aortic allograft model. Transplant. Proc. 25:1993;754-755.
    • (1993) Transplant. Proc. , vol.25 , pp. 754-755
    • Steele, D.M.1    Hullett, D.A.2    Bechstein, W.O.3
  • 133
    • 0030068297 scopus 로고    scopus 로고
    • Enhanced renal allograft rejection by inhibitors of alloreactivity
    • Stojanovic T., Grave H.J., Gieseler R.K.et al. Enhanced renal allograft rejection by inhibitors of alloreactivity. Lab. Invest. 74:1996;496-512.
    • (1996) Lab. Invest. , vol.74 , pp. 496-512
    • Stojanovic, T.1    Grave, H.J.2    Gieseler, R.K.3
  • 134
    • 0343046652 scopus 로고
    • Biosynthesis of nucleotides
    • New York: Freeman
    • Stryer L. Biosynthesis of nucleotides. Biochemistry. 3rd edn. 1988;602-626 Freeman, New York.
    • (1988) Biochemistry 3rd Edn. , pp. 602-626
    • Stryer, L.1
  • 135
    • 0029778443 scopus 로고    scopus 로고
    • Apoptosis of cardiac myocytes during cardiac allograft rejection. Relation to inhibition of nitric oxide synthase
    • Szabolcs M., Michler R.E., Yang X.et al. Apoptosis of cardiac myocytes during cardiac allograft rejection. Relation to inhibition of nitric oxide synthase. Circulation. 94:1996;1665-1673.
    • (1996) Circulation , vol.94 , pp. 1665-1673
    • Szabolcs, M.1    Michler, R.E.2    Yang, X.3
  • 136
    • 0032571288 scopus 로고    scopus 로고
    • Apoptosis and increased expression of inducible nitric oxide synthase in human allograft rejection
    • Szabolcs M.J., Ravalli S., Minanov O.et al. Apoptosis and increased expression of inducible nitric oxide synthase in human allograft rejection. Transplantation. 65:1998;804-812.
    • (1998) Transplantation , vol.65 , pp. 804-812
    • Szabolcs, M.J.1    Ravalli, S.2    Minanov, O.3
  • 137
    • 0027831688 scopus 로고
    • Effects of combined administration of FK-506 and the purine biosynthesis inhibitors mizoribine or mycophenolic acid on lymphocyte DNA synthesis and T-cell activation molecule expression in human mixed lymphocyte cultures
    • Thomson A.W., Woo J., Yao G.Z.et al. Effects of combined administration of FK-506 and the purine biosynthesis inhibitors mizoribine or mycophenolic acid on lymphocyte DNA synthesis and T-cell activation molecule expression in human mixed lymphocyte cultures. Transplant. Immunol. 1:1993;146-150.
    • (1993) Transplant. Immunol. , vol.1 , pp. 146-150
    • Thomson, A.W.1    Woo, J.2    Yao, G.Z.3
  • 138
    • 85066230267 scopus 로고
    • Use of cyclosporin A in allogeneic bone marrow transplantation in the rat
    • Tutschka P.J., Beschorner W.E., Allison A.C.et al. Use of cyclosporin A in allogeneic bone marrow transplantation in the rat. Nature. 280:1979;148-150.
    • (1979) Nature , vol.280 , pp. 148-150
    • Tutschka, P.J.1    Beschorner, W.E.2    Allison, A.C.3
  • 140
    • 0023279580 scopus 로고
    • Purification, characterization and kinetic analysis of inosine-5′monophosphate dehydrogenase of Trichomonas foetus
    • Verham R., Meek T.D., Hedstrom L., Wang C.C. Purification, characterization and kinetic analysis of inosine-5′monophosphate dehydrogenase of Trichomonas foetus. Mol. Biochem. Parasitol. 24:1987;1-12.
    • (1987) Mol. Biochem. Parasitol. , vol.24 , pp. 1-12
    • Verham, R.1    Meek, T.D.2    Hedstrom, L.3    Wang, C.C.4
  • 142
    • 0032531068 scopus 로고    scopus 로고
    • Alterations in mRNA for inducible endothelial nitric oxide synthase and plasma nitric oxide with rejection and/or infection of allotransplanted lungs
    • Wang X., Lewis D.A., Kim H.K.et al. Alterations in mRNA for inducible endothelial nitric oxide synthase and plasma nitric oxide with rejection and/or infection of allotransplanted lungs. Transplantation. 66:1998;567-572.
    • (1998) Transplantation , vol.66 , pp. 567-572
    • Wang, X.1    Lewis, D.A.2    Kim, H.K.3
  • 143
    • 0010490454 scopus 로고    scopus 로고
    • Mycophenolate mofetil protects against renal ischemia-reperfusion injury by inhibiting osteopontin and ICAM-1 expression
    • (Abstr)
    • Wang W., Tong M.K.H., Lee S.H., Chan L. Mycophenolate mofetil protects against renal ischemia-reperfusion injury by inhibiting osteopontin and ICAM-1 expression. Transplantation. 67:1999;537. (Abstr).
    • (1999) Transplantation , vol.67 , pp. 537
    • Wang, W.1    Tong, M.K.H.2    Lee, S.H.3    Chan, L.4
  • 144
    • 0021270424 scopus 로고
    • Differential effects of inhibitors of purine metabolism on two trichomonad species
    • Wang C.C., Verham R., Cheng H.W.et al. Differential effects of inhibitors of purine metabolism on two trichomonad species. Biochem. Pharmacol. 33:1984;1323-1329.
    • (1984) Biochem. Pharmacol. , vol.33 , pp. 1323-1329
    • Wang, C.C.1    Verham, R.2    Cheng, H.W.3
  • 145
    • 0001881610 scopus 로고    scopus 로고
    • Nitric oxide production in renal transplant recipients and iNOS expression in renal allografts
    • (Abstr)
    • Watarai Y., Takeuchi I., Togashi H., Yoshioka M.et al. Nitric oxide production in renal transplant recipients and iNOS expression in renal allografts. Transplantation. 67:1999;S9. (Abstr).
    • (1999) Transplantation , vol.67 , pp. 9
    • Watarai, Y.1    Takeuchi, I.2    Togashi, H.3    Yoshioka, M.4
  • 146
    • 0027763315 scopus 로고
    • Mycophenolic acid and some antioxidants induce differentiation of monocytic lineage cells and augment production of the IL-1 receptor antagonist
    • Waters R., Webster D., Allison A.C. Mycophenolic acid and some antioxidants induce differentiation of monocytic lineage cells and augment production of the IL-1 receptor antagonist. Ann. N. Y. Acad. Sci. 696:1993;185-196.
    • (1993) Ann. N. Y. Acad. Sci. , vol.696 , pp. 185-196
    • Waters, R.1    Webster, D.2    Allison, A.C.3
  • 147
    • 85081191993 scopus 로고    scopus 로고
    • Mycophenolic acid (MPA) inhibits the over-expression of osteopontin and ICAM-1 proteins in ischemia/reperfusion injury
    • (Abstr)
    • Wei W., Tong M.K.H., Chan L. Mycophenolic acid (MPA) inhibits the over-expression of osteopontin and ICAM-1 proteins in ischemia/reperfusion injury. J. Am. Soc. Nephrol. 9:1999;660A. (Abstr).
    • (1999) J. Am. Soc. Nephrol. , vol.9
    • Wei, W.1    Tong, M.K.H.2    Chan, L.3
  • 148
    • 0342612538 scopus 로고    scopus 로고
    • Monocyte responses in patients with chronic renal transplant rejection: Beneficial effects of MMF-based immunosuppression
    • (Abstr)
    • Weimer R., Melk A., Daniel V.et al. Monocyte responses in patients with chronic renal transplant rejection: beneficial effects of MMF-based immunosuppression. Transplantation. 67:1999;27. (Abstr).
    • (1999) Transplantation , vol.67 , pp. 27
    • Weimer, R.1    Melk, A.2    Daniel, V.3
  • 150
    • 85081191263 scopus 로고    scopus 로고
    • Mycophenolate inhibits nitric oxide (NO) production via iNOS in renal allograft recipients
    • Winklhofer F., Dai F.-X., Cowley B.D. Jr.et al. Mycophenolate inhibits nitric oxide (NO) production via iNOS in renal allograft recipients. Transplantation. 67:1999;S218.
    • (1999) Transplantation , vol.67 , pp. 218
    • Winklhofer, F.1    Dai, F.-X.2    Cowley B.D., Jr.3
  • 151
    • 0342505924 scopus 로고
    • Antipurines and purine metabolism
    • Wolberg G. Antipurines and purine metabolism. Handb. Exp. Pharmacol. 85:1988;517-550.
    • (1988) Handb. Exp. Pharmacol. , vol.85 , pp. 517-550
    • Wolberg, G.1
  • 152
    • 0013665671 scopus 로고    scopus 로고
    • Treatment of high risk chronic GVHD with FK506, mycophenolate mofetil (MMF) and methylprednisolone (MP)
    • Wolff D., Kuerschner D., Skibbe T.et al. Treatment of high risk chronic GVHD with FK506, mycophenolate mofetil (MMF) and methylprednisolone (MP). Br. J. Haematol. 102:1998;210.
    • (1998) Br. J. Haematol. , vol.102 , pp. 210
    • Wolff, D.1    Kuerschner, D.2    Skibbe, T.3
  • 153
    • 0032915605 scopus 로고    scopus 로고
    • Time course and cellular localization of indicible nitric oxide synthases expression during cardiac allograft rejection
    • Worrall N.K., Misko P.P., Botney M.D.et al. Time course and cellular localization of indicible nitric oxide synthases expression during cardiac allograft rejection. Ann. Thorac. Surg. 67:1999;716-722.
    • (1999) Ann. Thorac. Surg. , vol.67 , pp. 716-722
    • Worrall, N.K.1    Misko, P.P.2    Botney, M.D.3
  • 154
    • 34249770076 scopus 로고
    • Mycophenolate mofetil: Mechanisms of action
    • Wu J.C. Mycophenolate mofetil: mechanisms of action. Perspect. Drug Discov. Design. 2:1994;185-204.
    • (1994) Perspect. Drug Discov. Design , vol.2 , pp. 185-204
    • Wu, J.C.1
  • 155
    • 0033019478 scopus 로고    scopus 로고
    • Peroxynitrite formation during rat hepatic allograft rejection
    • Yamaguchi Y., Olsabe K., Matsumura F.et al. Peroxynitrite formation during rat hepatic allograft rejection. Hepatology. 29:1999;777-784.
    • (1999) Hepatology , vol.29 , pp. 777-784
    • Yamaguchi, Y.1    Olsabe, K.2    Matsumura, F.3
  • 156
    • 0032055163 scopus 로고    scopus 로고
    • Synergism between mycophenolate mofetil and cyclosporine in preventing graft-versus-host disease among lethally irradiated dogs given DLA-nonidentical marrow grafts
    • Yu C., Seidel K., Nash R.A., Deeg H.J., Sandmaier B.M., Barsoukov A. Synergism between mycophenolate mofetil and cyclosporine in preventing graft-versus-host disease among lethally irradiated dogs given DLA-nonidentical marrow grafts. Blood. 91:1998;2581-2587.
    • (1998) Blood , vol.91 , pp. 2581-2587
    • Yu, C.1    Seidel, K.2    Nash, R.A.3    Deeg, H.J.4    Sandmaier, B.M.5    Barsoukov, A.6
  • 157
    • 0008909802 scopus 로고    scopus 로고
    • Mycophenolate mofetil reduces tissue damage in an experimental model of colitis in rats
    • Zeeh J.M., Zorlu I., Riley N.E., Goebell H., Dignass A.U. Mycophenolate mofetil reduces tissue damage in an experimental model of colitis in rats. Gastroenterology. 114(4 (Pt. 2)):1998;A1122.
    • (1998) Gastroenterology , vol.114 , Issue.4 PT. 2 , pp. 1122
    • Zeeh, J.M.1    Zorlu, I.2    Riley, N.E.3    Goebell, H.4    Dignass, A.U.5
  • 158
    • 0030879283 scopus 로고    scopus 로고
    • Mycophenolate mofetil for severe autoimmune haemolytic anaemia
    • Zimmer-Molsberger B., Knauf W., Thiel E. Mycophenolate mofetil for severe autoimmune haemolytic anaemia. Lancet. 350:1997;1003-1004.
    • (1997) Lancet , vol.350 , pp. 1003-1004
    • Zimmer-Molsberger, B.1    Knauf, W.2    Thiel, E.3
  • 160
    • 0032077499 scopus 로고    scopus 로고
    • Myocytes isolated from rejecting transplanted hearts exhibit reduced basal shortening which is reversible by aminoguanidine
    • Ziolo M.T., Bollinger S.S., Wabler G.M. Myocytes isolated from rejecting transplanted hearts exhibit reduced basal shortening which is reversible by aminoguanidine. J. Mol. Cell Cardiol. 30:1998;1009-1017.
    • (1998) J. Mol. Cell Cardiol. , vol.30 , pp. 1009-1017
    • Ziolo, M.T.1    Bollinger, S.S.2    Wabler, G.M.3
  • 161
    • 0031759148 scopus 로고    scopus 로고
    • Mycophenolic acid: A new approach to the therapy of experimental mesangial proliferative glomerulonephritis
    • Ziswiler R., Steinman-Niggli K., Kappeler A.et al. Mycophenolic acid: a new approach to the therapy of experimental mesangial proliferative glomerulonephritis. J. Am. Soc. Nephrol. 9:1998;2055-2066.
    • (1998) J. Am. Soc. Nephrol. , vol.9 , pp. 2055-2066
    • Ziswiler, R.1    Steinman-Niggli, K.2    Kappeler, A.3


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