Vascular endothelial growth factor (VEGF) expression in prostate cancer and benign prostatic hyperplasia

Journal of Urology

Volumn 157, Issue 6, 1997, Pages 2323-2328

  Jackson, Michael W ^a   Bentel, Jacqueline M ^a   Tilley, Wayne D ^a  

^a FLINDERS UNIVERSITY   (Australia)

Author keywords

angiogenesis factor; immunoblotting; immunohistochemistry; prostatic neoplasms

Indexed keywords

ANGIOGENIC FACTOR; VASCULOTROPIN;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE HYPERTROPHY; PROTEIN LOCALIZATION; STROMA CELL;

EID: 0030993053     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(01)64774-8     Document Type: Article

References (52)

1. Greller, J.: Clinical review: 67: Approach to chemoprevention of prostate cancer. J. Clin. Endocrinol. Metab., 80: 717, 1995.
2. Gittes, R. F.: Carcinoma of the prostate. N. Engl. J. Med., 324: 236, 1991.
3. Garnick, M. B.: The dilemmas of prostate cancer. Sci. Am., 270: 72, 1994.
4. Folkman, J.: Tumor angiogenesis: therapeutic implications. N. Engl. J. Med., 285: 1182, 1971.
5. Folkman, J. and Shing, Y. Angiogenesis. J. Biol. Chem., 267: 10931, 1992.
6. Shing, Y., Folkman, J., Sullivan, R., Butterfield, C., Murray, J. and Klagsbrun, M.: Heparin affinity: purification of a tumor-derived capillary endothelial cell growth factor. Science., 223: 1296, 1984.
7. Fett, J. W., Strydom, D. J., Lobb, R. R., Alderman, E. M., Bethune, J. L., Riordan, J. F. and Vallee, B. L.: Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells. Biochemistry, 24: 5480, 1985.
8. Schott, R. J. and Morrow, L. A.: Growth factors and angiogenesis. Cardiovasc. Res., 27: 1155, 1993.
9. Connolly, D. T., Heuvelman, D. M., Nelson, R., Olander, J. V., Eppley, B. L., Delfino, J. J., Siegel, N. R., Leimgruber, R. M. and Feder, J.: Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J. Clin. Invest., 84: 1470, 1989.
10. Leung, D. W., Cachianes, G., Kuang, W. J., Goeddel, D. V. and Ferrara, N.: Vascular endothelial growth factor is a secreted angiogenic mitogen. Science, 246: 1306, 1989.
11. Liotta, L. A., Kleinerman, J. and Saidel, G. M.: Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation. Cancer Res., 34: 997, 1974.
12. Jiang, W. G., Puntis, M. C. and Hallett, M. B.: Molecular and cellular basis of cancer invasion and metastasis: implications for treatment. Br. J. Surg., 81: 1576, 1994.
13. Weidner, N., Semple, J. P., Welch, W. R. and Folkman, J.: Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N. Engl. J. Med., 324: 1, 1991.
14. Macchiarini, P., Fontanini, G., Dulmet, E., de Montpreville, V., Chapelier, A. R., Cerrina, J., Ladurie, F. L. and Dartevelle, P. G.: Angiogenesis: an indicator of metastasis in non-small cell lung cancer invading the thoracic inlet. Ann. Thorac. Surg., 57: 1534, 1994.
15. Takahashi, Y., Kitadai, Y., Bucana, C. D., Cleary, K. R. and Ellis, L. M.: Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer. Res., 55: 3964, 1995.
16. Weidner, N., Carroll, P. R., Flax, J., Blumenfeld, W. and Folkman, J.: Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am. J. Pathol., 143: 401, 1993.
17. Ferrara, N. and Henzel, W. J.: Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem. Biophys. Res. Commun., 161: 851, 1989.
18. Senger, D. R., Perruzzi, C. A., Feder, J. and Dvorak, H. F.: A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines. Cancer Res., 46: 5629, 1986.
19. Conn, G., Bayne, M. L., Soderman, D. D., Kwok, P. W., Sullivan, K. A., Palisi, T. M., Hope, D. A. and Thomas, K. A.: Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor. Proc. Natl. Acad. Sci. USA, 87: 2628, 1990.
20. Houck, K. A., Ferrara, N., Winer, J., Cachianes, G., Li, B. and Leung, D. W.: The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol. Endocrinol., 5: 1806, 1991.
21. Ferrara, N., Houck, K., Jakeman, L. and Leung, D. W.: Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocrine Reviews, 13: 18, 1992.
22. Ferrara, N., Houck, K. A., Jakeman, L. B., Winer, J. and Leung, D. W.: The vascular endothelial growth factor family of polypeptides. J. Cell. Biochem., 47: 211, 1991.
23. Charnock Jones, D. S., Sharkey, A. M., Rajput Williams, J., Burch, D., Schofield, J. P., Fountain, S. A., Boocock, C. A. and Smith, S. K.: Identification and localization of alternately spliced mRNAs for vascular endothelial growth factor in human uterus and estrogen regulation in endometrial carcinoma cell lines. Biol. Reprod., 48: 1120, 1993.
24. Plate, K. H., Breier, G., Weich, H. A. and Risau, W.: Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo. Nature, 359: 845, 1992.
25. Brown, L. F., Berse, B., Jackman, R. W., Tognazzi, K., Manseau, E. J., Senger, D. R. and Dvorak, H. F.: Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Res., 53: 4727, 1993.
26. Boocock, C. A., Charnock Jones, D. S., Sharkey, A. M., McLaren, J., Barker, P. J., Wright, K. A., Twentyman, P. R. and Smith, S. K.: Expression of vascular endothelial growth factor and its receptors fit and KDR in ovarian carcinoma. J. Natl. Cancer. Inst., 87: 506, 1995.
27. Brown, L. F., Berse, B., Jackman, R. W., Tognazzi, K., Guidi, A. J., Dvorak, H. F., Senger, D. R., Connolly, J. L. and Schnitt, S. J.: Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum. Pathol., 26: 86, 1995.
28. Yoshiji, H., Gomez, D. E., Shibuya, M. and Thorgeirsson, U. P.: Expression of vascular endothelial growth factor, its receptor, and other angiogenic factors in human breast cancer. Cancer Res., 56: 2013, 1996.
29. Claffey, K. P., Brown, L. F., del Aguila, L. F., Tognazzi, K., Yeo, K. T., Manseau, E. J. and Dvorak, H. F.: Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis. Cancer Res., 56: 172, 1996.
30. Saleh, M., Stacker, S. A. and Wilks, A. F.: Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence. Cancer Res., 56: 393, 1996.
31. Warren, R. S., Yuan, H., Matli, M. R., Gillett, N. A. and Ferrara, N.: Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis. J. Clin. Invest., 95: 1789, 1995.
32. Kim, K. J., Li, B., Winer, J., Armanini, M., Gillett, N., Phillips, H. S. and Ferrara, N.: Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo. Nature, 362: 841, 1993.
33. Toi, M., Inada, K., Suzuki, H. and Tominaga, T.: Tumor angiogenesis in breast cancer: its importance as a prognostic indicator and the association with vascular endothelial growth factor expression. Breast Cancer Res. Treat., 36: 193, 1995.
34. Brown, L. F., Yeo, K. T., Berse, B., Morgentaler, A. Dvorak, H. F. and Rosen, S.: Vascular permeability factor (vascular endothelial growth factor) is strongly expressed in the normal male genital tract and is present in substantial quantities in semen. J. Urol., 154: 576, 1995.
35. Harper, M. E., Glynne-Jones, E., Goddard, L., Thurston, V. J. and Griffiths, K.: Vascular endothelial growth factor (VEGF) expression in prostatic tumors and its relationship to neuroendocrine cells. Br. J. Cancer, 74: 910, 1996.
36. Khoury, S.: Staging of prostate cancer. In: Urology: Prostate Cancer. Edited by S. Khoury, C. Chatelain, G. Murphy and L. Denis. Boissy-le-Cutte, France: F.I.I.S, chapt. 9, pp. 149-53, 1990.
37. Cattoretti, G., Becker, M. H., Key, G., Duchrow, M., Schluter, C., Galle, J. and Gerdes, J.: Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J. Pathol., 168: 357, 1992.
38. Sambrook, J., Fritsch, E. F. and Maniatis, T. Molecular Cloning: A Laboratory Manual, 2nd ed., Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, pp. 7.19-7.22, 1989.
39. Ricciardelli, C., Horsfall, D. J., Sykes, P. J., Marshall, V. R. and Tilley, W. D.: Effects of 17β-estradiol and 5α-dihydrotestosterone on guinea pig smooth muscle cell proliferation and steroid receptor expression in vitro. J. Endocrinol., 140: 373, 1994.
40. Tilley, W. D., Buchanan, G., Hickey, T. E. and Bentel, J. M.: Mutations in the androgen receptor gene are associated with progression of human prostate cancer to androgen independence. Clin. Cancer Res., 2: 277, 1996.
41. Dvorak, H. F., Sioussat, T. M., Brown, L. F., Berse, B., Nagy, J. A., Sotrel, A., Manseau, E. J., Van de Water, L. and Senger, D. R.: Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: concentration in tumor blood vessels. J. Exp. Med., 174: 1275 1991.
42. Pe'er, J., Shweiki, D., Itin, A., Hemo, I., Gnessin, H. and Keshet, E.: Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularizing ocular diseases. Lab. Invest., 72: 638, 1995.
43. Tuder, R. M., Flook, B. E. and Voelkel, N. F.: Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. Modulation of gene expression by nitric oxide. J. Clin. Invest., 95: 1798, 1995.
44. Tsai, J. C., Goldman, C. K. and Gillespie, G. Y.: Vascular endothelial growth factor in human glioma cell lines: induced secretion by EGF, PDGF-BB, and bFGF. J. Neurosurg., 82: 864, 1995.
45. Wizigmann Voos, S., Breier, G., Risau, W. and Plate, K. H.: Up-regulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas. Cancer Res., 55: 1358, 1995.
46. Shiraishi, A., Ishiwata, T., Shoji, T. and Asano, G.: Expression of PCNA basic fibroblast growth factor, FGF-receptor and vascular endothelial growth factor in adenomas and carcinomas of human colon. Acta Histochem. Cytochem., 28: 21, 1995.
47. Vlodavsky, I., Bar Shavit, R., Ishai Michaeli, R., Bashkin, P. and Fuks, Z.: Extracellular sequestration and release of fibroblast growth factor: a regulatory mechanism? Trends Biochem. Sci., 16: 268, 1991.
48. Pepper, M. S., Ferrara, N., Orci, L. and Montesano, R.: Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem. Biophys. Res. Commun., 181: 902, 1991.
49. Unemori, E. N., Ferrara, N., Bauer, E. A. and Amento, E. P.: Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells. J. Cell Physiol., 153: 557, 1992.
50. Folkman, J.: Angiogenesis in cancer, vascular, rheumatoid and other diseases. Nature Medicine, 1: 27, 1995.
51. Ferrara, N., Winer, J. and Burton, T.: Aortic smooth muscle cells express and secrete vascular endothelial growth factor. Growth Factors, 5: 141, 1991.
52. Sommer, A. and Rifkin, D. B.: Interaction of heparin with human basic fibroblast growth factor: protection of the angiogenic protein from proteolytic degradation by a glycosaminoglycan. J. Cell Physiol., 138: 215, 1989.