The nuclear receptor ligand-binding domain: A family-based structure analysis

Current Medicinal Chemistry

Volumn 12, Issue 9, 2005, Pages 1001-1016

  Folkertsma, Simon ^a   va Noort, Paula I ^b   Brandt, Ralph F J ^b   Bettler, Emmanuel ^c   Vriend, Gerrit ^a   de Vlieg, Jacob ^a,b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NV ORGANON   (Netherlands)

^c INSTITUT DE BIOLOGIE ET CHIMIE DES PROTÉINES   (France)

Author keywords

Cofactor binding; Data mining; Dimerization; Ligand binding; Nuclear receptor; Protein structure

Indexed keywords

ALITRETINOIN; CELL NUCLEUS RECEPTOR; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; METRIBOLONE; RETINOIC ACID; RETINOID X RECEPTOR; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; CANCER; CROSS REACTION; CRYSTAL STRUCTURE; DIABETES MELLITUS; DIMERIZATION; DNA BINDING; DRUG DESIGN; HUMAN; INFERTILITY; LIGAND BINDING; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; RESIDUE ANALYSIS; REVIEW; STRUCTURE ANALYSIS;

BINDING SITES; DATABASES, GENETIC; DIMERIZATION; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 18744391429     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867053764699     Document Type: Review

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