메뉴 건너뛰기




Volumn 9, Issue 8, 1998, Pages 2185-2200

Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; BETA CATENIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; RAS PROTEIN; SCATTER FACTOR; UVOMORULIN;

EID: 0031829163     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.9.8.2185     Document Type: Article
Times cited : (301)

References (58)
  • 1
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo
    • Alessi, D.R., Cuenda, A., Cohen, P., Dudley, D.T., and Saltiel, A.R. (1995). PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo. J. Biol. Chem. 270, 27489-27494.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 3
    • 0023918616 scopus 로고
    • Characterization of ZO-1, a protein component of tight junction from mouse liver and Madin-Darby canine kidney cells
    • Anderson, J.M., Stevenson, B.R., Jesaitis, L.A., Goodenough, D.A., and Mooseker, M.S. (1988). Characterization of ZO-1, a protein component of tight junction from mouse liver and Madin-Darby canine kidney cells. J. Cell Biol. 106, 1141-1149.
    • (1988) J. Cell Biol. , vol.106 , pp. 1141-1149
    • Anderson, J.M.1    Stevenson, B.R.2    Jesaitis, L.A.3    Goodenough, D.A.4    Mooseker, M.S.5
  • 4
    • 0028175091 scopus 로고
    • Raf meets Ras: Completing the framework of a signal transduction pathway
    • Avruch, J., Zhang, X.-F., and Kyriakis, J.M. (1994). Raf meets Ras: completing the framework of a signal transduction pathway. Trends Biochem. Sci. 19, 279-283.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 279-283
    • Avruch, J.1    Zhang, X.-F.2    Kyriakis, J.M.3
  • 5
    • 0029799520 scopus 로고    scopus 로고
    • Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein
    • Balda, M.S., Whitney, J.A., Flores, C., Gonzáles, S., Cereijdo, M., and Matter, K. (1996). Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein. J. Cell Biol. 134, 1031-1049.
    • (1996) J. Cell Biol. , vol.134 , pp. 1031-1049
    • Balda, M.S.1    Whitney, J.A.2    Flores, C.3    Gonzáles, S.4    Cereijdo, M.5    Matter, K.6
  • 6
    • 0342327346 scopus 로고    scopus 로고
    • Cadherins, catenins and APC protein: Interplay between cytoskeletal complexes and signaling pathways
    • Barth, A.I.M., Näthke, I.S., and Nelson, W.J. (1997). Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways. Curr. Opin. Cell Biol. 9, 683-690.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 683-690
    • Barth, A.I.M.1    Näthke, I.S.2    Nelson, W.J.3
  • 7
    • 0027507028 scopus 로고
    • Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/ β-catenin complex in cells transformed with a temperature sensitive v-SRC gene
    • Behrens, J., Vakaet, L., Friis, R., Winterhager, E., van Roy, F., Mareel, M.M., and Birchmeier, W. (1993). Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/ β-catenin complex in cells transformed with a temperature sensitive v-SRC gene. J. Cell Biol. 120, 757-766.
    • (1993) J. Cell Biol. , vol.120 , pp. 757-766
    • Behrens, J.1    Vakaet, L.2    Friis, R.3    Winterhager, E.4    Van Roy, F.5    Mareel, M.M.6    Birchmeier, W.7
  • 8
    • 0028268338 scopus 로고
    • Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorgenicity
    • Bellusci, S., Moens, G., Gaudino, G., Comoglio, P., Nakamura, T., Thierry, J.P., and Jouanneau, J. (1994). Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorgenicity. Oncogene 9, 1091-1099.
    • (1994) Oncogene , vol.9 , pp. 1091-1099
    • Bellusci, S.1    Moens, G.2    Gaudino, G.3    Comoglio, P.4    Nakamura, T.5    Thierry, J.P.6    Jouanneau, J.7
  • 9
    • 0031050310 scopus 로고    scopus 로고
    • Cytoskeletal and adhesion proteins as tumor suppressors
    • Ben-Ze'ev, A. (1997). Cytoskeletal and adhesion proteins as tumor suppressors. Curr. Opin. Cell Biol. 9, 99-108.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 99-108
    • Ben-Ze'ev, A.1
  • 11
    • 0030968177 scopus 로고    scopus 로고
    • The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts
    • Braga, V.M.M., Machesky, L.M., Hall, A., and Hotchin, N.A. (1997). The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J. Cell Biol. 137, 1421-1431.
    • (1997) J. Cell Biol. , vol.137 , pp. 1421-1431
    • Braga, V.M.M.1    Machesky, L.M.2    Hall, A.3    Hotchin, N.A.4
  • 12
    • 0028228616 scopus 로고
    • Activation of the MAP kinase kinase is necessary and sufficient for PC12 differentiation and transformation of NIH 3T3 cells
    • Cowley, S., Paterson, H., Kemp, P., and Marshall, C.J. (1994). Activation of the MAP kinase kinase is necessary and sufficient for PC12 differentiation and transformation of NIH 3T3 cells. Cell 77, 841-852.
    • (1994) Cell , vol.77 , pp. 841-852
    • Cowley, S.1    Paterson, H.2    Kemp, P.3    Marshall, C.J.4
  • 13
    • 0026195967 scopus 로고
    • Scatter factor affects major changes in the cytoskeletal organization of epithelial cells
    • Dowrick, P.G., Prescott, A.R., and Warn, R.M. (1991). Scatter factor affects major changes in the cytoskeletal organization of epithelial cells. Cytokine 3, 299-310.
    • (1991) Cytokine , vol.3 , pp. 299-310
    • Dowrick, P.G.1    Prescott, A.R.2    Warn, R.M.3
  • 15
    • 0008222162 scopus 로고
    • Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement
    • Gherardi, E., Gray, J., Stoker, M., Perryman, M., and Furlong, R. (1989). Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement. Proc. Natl. Acad. Sci. USA 86, 5844-5848.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 5844-5848
    • Gherardi, E.1    Gray, J.2    Stoker, M.3    Perryman, M.4    Furlong, R.5
  • 16
    • 0025788025 scopus 로고
    • The tyrosine-phosphorylated hepatocyte growth factor/scatter factor receptor associates with phosphatidylinositol 3-kinase
    • Graziani, A., Gramaglia, D., Cantley, L.C., and Comoglio, P.M. (1991). The tyrosine-phosphorylated hepatocyte growth factor/scatter factor receptor associates with phosphatidylinositol 3-kinase. J. Biol. Chem. 266, 22087-22090.
    • (1991) J. Biol. Chem. , vol.266 , pp. 22087-22090
    • Graziani, A.1    Gramaglia, D.2    Cantley, L.C.3    Comoglio, P.M.4
  • 17
    • 0027322529 scopus 로고
    • Hepatocyte growth factor/scatter factor stimulates the rasguanine nucleotide exchanger
    • Graziani, A., Gramaglia, D., dalla Zonca, P., and Comoglio, P.M. (1993). Hepatocyte growth factor/scatter factor stimulates the rasguanine nucleotide exchanger. J. Biol. Chem. 268, 9165-9168.
    • (1993) J. Biol. Chem. , vol.268 , pp. 9165-9168
    • Graziani, A.1    Gramaglia, D.2    Dalla Zonca, P.3    Comoglio, P.M.4
  • 18
    • 0027715358 scopus 로고
    • Breaking through the tight junction barrier
    • Gumbiner, B. (1993). Breaking through the tight junction barrier. J. Cell Biol. 123, 1631-1633.
    • (1993) J. Cell Biol. , vol.123 , pp. 1631-1633
    • Gumbiner, B.1
  • 19
    • 0028170820 scopus 로고
    • Small GTP-binding proteins and the regulation of the actin cytoskeleton
    • Hall, A. (1994). Small GTP-binding proteins and the regulation of the actin cytoskeleton. Annu. Rev. Cell Biol. 10, 31-54.
    • (1994) Annu. Rev. Cell Biol. , vol.10 , pp. 31-54
    • Hall, A.1
  • 21
    • 15144353776 scopus 로고    scopus 로고
    • Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav
    • Han, J., Luby-Phelps, K., Das, B., Shu, X., Xia, Y., Mosteller, R.D., Krishna, U.M., Falck, J.R., White, M.A., and Broek, D. (1998). Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav. Science 279, 558-560.
    • (1998) Science , vol.279 , pp. 558-560
    • Han, J.1    Luby-Phelps, K.2    Das, B.3    Shu, X.4    Xia, Y.5    Mosteller, R.D.6    Krishna, U.M.7    Falck, J.R.8    White, M.A.9    Broek, D.10
  • 22
    • 0028142230 scopus 로고
    • The motility signal of scatter factor/hepatocyte growth factor mediated through the receptor tyrosine kinase met requires intracellular action of ras
    • Hartmann, G., Weidner, K.M., Schwarz, H., and Birchmeier, W. (1994). The motility signal of scatter factor/hepatocyte growth factor mediated through the receptor tyrosine kinase met requires intracellular action of ras. J. Cell Biol. 269, 21936-21939.
    • (1994) J. Cell Biol. , vol.269 , pp. 21936-21939
    • Hartmann, G.1    Weidner, K.M.2    Schwarz, H.3    Birchmeier, W.4
  • 23
    • 0029278739 scopus 로고
    • PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase
    • Hawkins, P.T. et al (1995). PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase. Curr. Biol. 5, 393-403.
    • (1995) Curr. Biol. , vol.5 , pp. 393-403
    • Hawkins, P.T.1
  • 24
    • 0030847535 scopus 로고    scopus 로고
    • 3 gets its message across
    • 3 gets its message across. Science 277, 534.
    • (1997) Science , vol.277 , pp. 534
    • Hemmings, B.A.1
  • 26
    • 0030045346 scopus 로고    scopus 로고
    • Cell migration: A physically integrated molecular process
    • Lauffenburger, D.A., and Horwitz, A.F. (1996). Cell migration: a physically integrated molecular process. Cell 84, 359-369.
    • (1996) Cell , vol.84 , pp. 359-369
    • Lauffenburger, D.A.1    Horwitz, A.F.2
  • 28
    • 0025824738 scopus 로고
    • Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor
    • Montesano, R., Matsumoto, K., Nakamura, T., and Orci, L. (1991). Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell 67, 901-908.
    • (1991) Cell , vol.67 , pp. 901-908
    • Montesano, R.1    Matsumoto, K.2    Nakamura, T.3    Orci, L.4
  • 30
    • 0029034774 scopus 로고
    • Inhibition of MAP kinase kinase blocks the differentiation of PC12 cells induced by nerve growth factor
    • Pang, L., Sawade, T., Decker, S.J., and Saltiel, A.R. (1995). Inhibition of MAP kinase kinase blocks the differentiation of PC12 cells induced by nerve growth factor. J. Biol. Chem. 270, 13585-13588.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13585-13588
    • Pang, L.1    Sawade, T.2    Decker, S.J.3    Saltiel, A.R.4
  • 31
    • 0029320454 scopus 로고
    • Intracellular signalling. PI 3-kinase puts GTP on the rac
    • Parker, P.J. (1995). Intracellular signalling. PI 3-kinase puts GTP on the rac. Curr. Biol. 5, 57-59.
    • (1995) Curr. Biol. , vol.5 , pp. 57-59
    • Parker, P.J.1
  • 32
    • 0023372476 scopus 로고
    • Structure and assembly of desmosome junctions: Biosynthesis, processing, and transport of the major protein and glycoprotein components in cultured epithelial cells
    • Penn, E.J., Hobson, C., Rees, D.A., and Magee, A.I. (1987). Structure and assembly of desmosome junctions: biosynthesis, processing, and transport of the major protein and glycoprotein components in cultured epithelial cells. J. Cell Biol. 205, 57-68.
    • (1987) J. Cell Biol. , vol.205 , pp. 57-68
    • Penn, E.J.1    Hobson, C.2    Rees, D.A.3    Magee, A.I.4
  • 33
    • 0027219258 scopus 로고
    • A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor
    • Ponzetto, C., Bardelli, A., Maina, F., Longati, P., Panayotou, G., Dhand, R., Waterfield, M.D., and Comoglio, P.M. (1993). A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor. Mol. Cell. Biol. 13, 4600-4608.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4600-4608
    • Ponzetto, C.1    Bardelli, A.2    Maina, F.3    Longati, P.4    Panayotou, G.5    Dhand, R.6    Waterfield, M.D.7    Comoglio, P.M.8
  • 34
    • 0028351702 scopus 로고
    • A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family
    • Ponzetto, C., Bardelli, A., Zhen, Z., Maina, F., dalla Zonca, P., Giordano, S., Graziani, A., Panayotou, G., and Comoglio, P.M. (1994). A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family. Cell 77, 261-271.
    • (1994) Cell , vol.77 , pp. 261-271
    • Ponzetto, C.1    Bardelli, A.2    Zhen, Z.3    Maina, F.4    Dalla Zonca, P.5    Giordano, S.6    Graziani, A.7    Panayotou, G.8    Comoglio, P.M.9
  • 35
    • 0028894787 scopus 로고
    • Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac and Rho in MDCK cells
    • Ridley, A.J., Comoglio, P.M., and Hall, A. (1995). Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac and Rho in MDCK cells. Mol. Cell. Biol. 15, 1110-1122.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1110-1122
    • Ridley, A.J.1    Comoglio, P.M.2    Hall, A.3
  • 36
    • 0026654125 scopus 로고
    • The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling
    • Ridley, A.J., Paterson, H.F., Johnston, C.L., Diekmann, D., and Hall, A. (1992). The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling. Cell 70, 401-410.
    • (1992) Cell , vol.70 , pp. 401-410
    • Ridley, A.J.1    Paterson, H.F.2    Johnston, C.L.3    Diekmann, D.4    Hall, A.5
  • 37
    • 0024315423 scopus 로고
    • Morphogenesis of the polarized epithelial cell phenotype
    • Rodriguez-Boulan, E., and Nelson, W.J. (1989). Morphogenesis of the polarized epithelial cell phenotype. Science 245, 718-725.
    • (1989) Science , vol.245 , pp. 718-725
    • Rodriguez-Boulan, E.1    Nelson, W.J.2
  • 41
    • 0028850053 scopus 로고
    • Hepatocyte growth factor-induced scatter of Madin-darby canine kidney cells requires phosphatidylinositol 3-kinase
    • Royal, I., and Park, M. (1995). Hepatocyte growth factor-induced scatter of Madin-darby canine kidney cells requires phosphatidylinositol 3-kinase. J. Biol. Chem. 270, 27780-27787.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27780-27787
    • Royal, I.1    Park, M.2
  • 42
    • 0031005659 scopus 로고    scopus 로고
    • The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition
    • Savagner, P., Yamada, K.M., and Thiery, J.P. (1997). The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition. J. Cell Biol. 137, 1403-1419.
    • (1997) J. Cell Biol. , vol.137 , pp. 1403-1419
    • Savagner, P.1    Yamada, K.M.2    Thiery, J.P.3
  • 44
    • 0025977370 scopus 로고
    • Multilayering and loss of apical polarity in MDCK cells transformed with K-ras
    • Schoenenberger, C.A., Zuk, A., Kendall, D., and Matlin, K.S. (1991). Multilayering and loss of apical polarity in MDCK cells transformed with K-ras. J. Cell Biol. 112, 873-889.
    • (1991) J. Cell Biol. , vol.112 , pp. 873-889
    • Schoenenberger, C.A.1    Zuk, A.2    Kendall, D.3    Matlin, K.S.4
  • 45
    • 0025933683 scopus 로고
    • Biosynthesis of the cell adhesion molecule uvomorulin (E-cadherin) in Madin-Darby canine kidney epithelial cells
    • Shore, E.M., and Nelson, W.J. (1991). Biosynthesis of the cell adhesion molecule uvomorulin (E-cadherin) in Madin-Darby canine kidney epithelial cells. J. Biol. Chem. 266, 19672-19680.
    • (1991) J. Biol. Chem. , vol.266 , pp. 19672-19680
    • Shore, E.M.1    Nelson, W.J.2
  • 46
    • 0024202115 scopus 로고
    • Localization of the tight junction protein, ZO-1, is modulated by extracellular calcium and cell-cell contact in Madin-Darby canine kidney epithelial cells
    • Siliciano, J.D., and Goodenough, D.A. (1988). Localization of the tight junction protein, ZO-1, is modulated by extracellular calcium and cell-cell contact in Madin-Darby canine kidney epithelial cells J. Cell Biol. 107, 2389-2399.
    • (1988) J. Cell Biol. , vol.107 , pp. 2389-2399
    • Siliciano, J.D.1    Goodenough, D.A.2
  • 47
    • 0023661693 scopus 로고
    • Scatter factor is a fibroblast-derived modulator of epithelial cell motility
    • Stoker, M., Gheradi, E., Perryman, M., and Gray, J. (1987). Scatter factor is a fibroblast-derived modulator of epithelial cell motility. Nature 327, 239-242.
    • (1987) Nature , vol.327 , pp. 239-242
    • Stoker, M.1    Gheradi, E.2    Perryman, M.3    Gray, J.4
  • 48
    • 0022269174 scopus 로고
    • An epithelial scatter factor released by embryo fibroblasts
    • Stoker, M., and Perryman, M. (1985). An epithelial scatter factor released by embryo fibroblasts. J. Cell Sci. 77, 209-223.
    • (1985) J. Cell Sci. , vol.77 , pp. 209-223
    • Stoker, M.1    Perryman, M.2
  • 49
    • 0030718609 scopus 로고    scopus 로고
    • Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells
    • Takaishi, K., Sasaki, T., Kotani, H., Nishioka, H., and Takai, Y. (1997). Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells. J. Cell Biol. 139, 1047-1059.
    • (1997) J. Cell Biol. , vol.139 , pp. 1047-1059
    • Takaishi, K.1    Sasaki, T.2    Kotani, H.3    Nishioka, H.4    Takai, Y.5
  • 50
    • 0029615381 scopus 로고
    • V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and β-catenin is not required for the shift
    • Takeda, H., Nagafuchi, A., Yonemura, S., Tsukita, S., Behrens, J., Birchmeier, W., and Tsukita, S. (1995). V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and β-catenin is not required for the shift. J. Cell Biol. 131, 1839-1847.
    • (1995) J. Cell Biol. , vol.131 , pp. 1839-1847
    • Takeda, H.1    Nagafuchi, A.2    Yonemura, S.3    Tsukita, S.4    Behrens, J.5    Birchmeier, W.6    Tsukita, S.7
  • 51
    • 0025894092 scopus 로고
    • Cadherin cell adhesion receptors as a morphogenetic regulator
    • Takeichi, M. (1991). Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251, 1451-1455.
    • (1991) Science , vol.251 , pp. 1451-1455
    • Takeichi, M.1
  • 52
    • 0031042493 scopus 로고    scopus 로고
    • Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton
    • Tapon, N., and Hall, A. (1997). Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton. Curr. Opin. Cell Biol. 9, 86-92.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 86-92
    • Tapon, N.1    Hall, A.2
  • 53
    • 0028911690 scopus 로고
    • Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor
    • Uehara, Y., Minowa, O., Mori, C., Shiota, K., Kuno, J., Noda, T., and Kitamura, N. (1995). Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor. Nature 373, 702-705.
    • (1995) Nature , vol.373 , pp. 702-705
    • Uehara, Y.1    Minowa, O.2    Mori, C.3    Shiota, K.4    Kuno, J.5    Noda, T.6    Kitamura, N.7
  • 55
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidlyinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
    • Vlahos, C.J., Matter, W.F., Hui, K.Y., and Brown, R.F. (1994). A specific inhibitor of phosphatidlyinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J. Cell Biol. 269, 5241-5248.
    • (1994) J. Cell Biol. , vol.269 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4
  • 56
    • 0027410889 scopus 로고
    • The met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter fcator/hepatocyte growth factor in epithelial cells
    • Weidner, K.M., Sachs, M., and Birchmeier, W. (1993). The met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter fcator/hepatocyte growth factor in epithelial cells. J. Cell Biol. 121, 145-154.
    • (1993) J. Cell Biol. , vol.121 , pp. 145-154
    • Weidner, K.M.1    Sachs, M.2    Birchmeier, W.3
  • 58
    • 0028999868 scopus 로고
    • The many faces of hepatocyte growth factor: From hepatopoiesis to hematopoiesis
    • Zarnegar, R., and Michalopoulos, G.K. (1995). The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis. J. Cell Biol. 129, 1177-1180.
    • (1995) J. Cell Biol. , vol.129 , pp. 1177-1180
    • Zarnegar, R.1    Michalopoulos, G.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.