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Volumn 5, Issue 3, 2005, Pages 267-279

Multi-nuclear platinum drugs: A new paradigm in chemotherapy

Author keywords

Anti cancer; BBR3005; BBR3464; BBR3571; BBR3610; Chemotherapy; Multi nuclear; Platinum

Indexed keywords

AMD 0473; AMD 494; AMD 508; AMD0473; AMD494; AMD508; AMMINEDICHLORO(2 METHYLPYRIDINE)PLATINUM; ANTIEMETIC AGENT; ANTINEOPLASTIC AGENT; BBR 3005; BBR 3464; BBR 3571; BBR 3610; BORON 10; CARBOPLATIN; CARBORANE DERIVATIVE; CISPLATIN; DRUG BINDING PROTEIN; EMETIC AGENT; JM 0473; JM0473; LOPERAMIDE; MANNITOL; MISMATCH REPAIR PROTEIN PMS2; NEW DRUG; OXALIPLATIN; PLASMA PROTEIN; PLATINUM DERIVATIVE; PROTEIN P53; SATRAPLATIN; UNCLASSIFIED DRUG;

EID: 18444405560     PISSN: 15680118     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568011053765994     Document Type: Review
Times cited : (108)

References (131)
  • 12
    • 18444369461 scopus 로고    scopus 로고
    • AMD494 contains a pyridine ring, with the chloro ligands in the platinum in the trans configuration. AMD508 contains the 2, 6-dimethylpyridine ligand
    • AMD494 contains a pyridine ring, with the chloro ligands in the platinum in the trans configuration. AMD508 contains the 2, 6-dimethylpyridine ligand.
  • 18
    • 18444401577 scopus 로고    scopus 로고
    • Anormed Product Profile: AMD0473 June
    • Anormed Product Profile: AMD0473 June 2004.
    • (2004)
  • 20
    • 18444412412 scopus 로고    scopus 로고
    • Cisplatin is currently sold around the world as an oncology drug by Bristol Myers-Squibb under the brand name Platinol™ and under the generic name CISplatin by Bedford. Sold as an aqueous solution (1 mg/mL with 9 mg/mL NaCl) it is used in the treatment of metastatic testicular tumours, metastatic ovarian tumours and advanced bladder cancer. Cisplatin is used as either a single agent, or in combination therapy with a range of other oncology drugs. Federal Drug Agency Product Label, Platinol, Oct
    • Cisplatin is currently sold around the world as an oncology drug by Bristol Myers-Squibb under the brand name Platinol™ and under the generic name CISplatin by Bedford. Sold as an aqueous solution (1 mg/mL with 9 mg/mL NaCl) it is used in the treatment of metastatic testicular tumours, metastatic ovarian tumours and advanced bladder cancer. Cisplatin is used as either a single agent, or in combination therapy with a range of other oncology drugs. Federal Drug Agency Product Label, Platinol, Oct 1999.
    • (1999)
  • 21
    • 18444404152 scopus 로고    scopus 로고
    • Federal Drug Agency Product Label, Paraplatin, Jun
    • Federal Drug Agency Product Label, Paraplatin, Jun 2001.
    • (2001)
  • 22
    • 0033861967 scopus 로고    scopus 로고
    • For a review of oxaliplatin see: Cassidy
    • For a review of oxaliplatin see: Cassidy, J. Int. J. Cancer Prevent., 2000, 54, 399.
    • (2000) J. Int. J. Cancer Prevent. , vol.54 , pp. 399
  • 26
    • 18444368271 scopus 로고    scopus 로고
    • Federal Drug Agency Product Label Eloxatin, Jan
    • Federal Drug Agency Product Label, Eloxatin, Jan 2004.
    • (2004)
  • 34
    • 18444404477 scopus 로고    scopus 로고
    • Farrell has an abbreviation scheme that relates the number of chloro ligands and their geometry on the metal complex in regard to the bridging linker. A complex with one chloro ligand on each platinum, trans to the bridging linker is referred to as 1,1/t,t. A complex with two cis chloro ligands is 2,2/c,c. A complex with one cis chloro ligand on the first platinum and two trans chloro ligands on the second platinum would be referred to as 1,2/c,t
    • Farrell has an abbreviation scheme that relates the number of chloro ligands and their geometry on the metal complex in regard to the bridging linker. A complex with one chloro ligand on each platinum, trans to the bridging linker is referred to as 1,1/t,t. A complex with two cis chloro ligands is 2,2/c,c. A complex with one cis chloro ligand on the first platinum and two trans chloro ligands on the second platinum would be referred to as 1,2/c,t.
  • 66
    • 18444384090 scopus 로고    scopus 로고
    • These drugs are currently being developed by Cell Technologies Inc (CTI) which merged with Novuspharma SpA in January Roche retains it right to first refusal over the drugs
    • These drugs are currently being developed by Cell Technologies Inc (CTI) which merged with Novuspharma SpA in January 2004. Roche retains it right to first refusal over the drugs.
    • (2004)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.