Effects of a novel trinuclear platinum complex in cisplatin-sensitive and cisplatin-resistant human ovarian cancer cell lines: Interference with cell cycle progression and induction of apoptosis

European Journal of Cancer

Volumn 37, Issue 5, 2001, Pages 649-659

  Orlandi, L ^a   Colella, G ^a   Bearzatto, A ^a   Abolafio, G ^a   Manzotti, C ^b   Daidone, M G ^a   Zaffaroni, N ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b Novuspharma SpA   (Italy)

Author keywords

Apoptosis; BBR 3464; Cell cycle perturbation; Cisplatin; Kinase activity; Mitochondrial membrane potential; Ovarian cancer

Indexed keywords

BBR 3464; CISPLATIN; DNA; LAMIN B; PLATINUM COMPLEX;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL DIVISION; CELL FRACTIONATION; CELL STRUCTURE; CONTROLLED STUDY; DEGRADATION; DNA DAMAGE; DNA MODIFICATION; DRUG ACCUMULATION; DRUG EXPOSURE; DRUG SENSITIVITY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; OVARY CARCINOMA; OVARY CELL; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CDC2 PROTEIN KINASE; CELL CYCLE; CYCLIN B; DRUG RESISTANCE, NEOPLASM; ELECTROPHORESIS, AGAR GEL; FEMALE; HUMANS; IMMUNOBLOTTING; ORGANOPLATINUM COMPOUNDS; OVARIAN NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0035062570     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(00)00445-7     Document Type: Article

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