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Journal of the American Chemical Society

Volumn 123, Issue 7, 2001, Pages 1316-1326

Kinetic analysis of the stepwise formation of a long-range DNA interstrand cross-link by a dinuclear platinum antitumor complex: Evidence for aquated intermediates and formation of both kinetically and thermodynamically controlled conformers

(5) Cox, J W a Berners Price, S J b Davies, M S b Qu, Y a Farrell, N a

a GRIFFITH UNIVERSITY (Australia)

b VIRGINIA COMMONWEALTH UNIVERSITY (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GUANINE; PLATINUM;

ANTINEOPLASTIC ACTIVITY; ARTICLE; COMPLEX FORMATION; CROSS LINKING; DRUG SYNTHESIS; ELECTRICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN BOND; KINETICS; MOLECULAR INTERACTION; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; THERMODYNAMICS;

ANTINEOPLASTIC AGENTS; DNA ADDUCTS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; ORGANOPLATINUM COMPOUNDS; PROTEIN BINDING; THERMODYNAMICS;

EID: 0035925158 PISSN: 00027863 EISSN: None Source Type: Journal
DOI: 10.1021/ja0012772 Document Type: Article

Times cited : (105)

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