Comparison of cytotoxicity and cellular accumulation of polynuclear platinum complexes in L1210 murine leukemia cell lines

Journal of Inorganic Biochemistry

Volumn 77, Issue 1-2, 1999, Pages 47-50

  Roberts, John D ^a,b   Peroutka, John ^a,b   Beggiolin, G ^d   Manzotti, C ^d   Piazzoni, L ^d   Farrell, Nicholas ^a,c  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^d Novuspharma SpA   (Italy)

Author keywords

Cisplatin polynuclear platinum complexes

Indexed keywords

BBR 3005; BBR 3464; BBR 3571; CISPLATIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CLINICAL TRIAL; COMPLEX FORMATION; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG RESISTANCE; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOUSE; NONHUMAN; PHASE 1 CLINICAL TRIAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CISPLATIN; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; LEUKEMIA L1210; MICE; MITOGUAZONE; ORGANOPLATINUM COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0033390141     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-0134(99)00137-3     Document Type: Article

References (12)

1. N. Farrell, S. Spinelli, in: N. Farrell (Ed.), Uses of Inorganic Chemistry in Medicine, Royal Society of Chemistry, Cambridge, UK, 1999, pp. 124-134.
2. Brabec V., Kašpárková J., Vrána O., Nováková O., Cox J., Qu Y., Farrell N. Biochemistry. 38:1999;6781.
3. J.D. Roberts, J. Peroutka, N. Farrell, J. Inorg. Biochem. 77 (1999) 51.
4. Perego P., Caserini C., Gatti L., Carenini N., Romanelli S., Supino R., Colangelo D., Viano I., Spinelli S., Pezzoni G., Manzotti C., Farrell N., Zunino F. Mol. Pharmacol. 55:1999;528.
5. N. Farrell, Y. Qu, U. Bierbach, M. Valsecchi, E. Menta, in: B. Lippert (Ed.), 30 Years of Cisplatin - Chemistry and Biochemistry of a Leading Anticancer Drug, Springer, Berlin, 1999, pp. 479-496.
6. Rauter H., Di Domenico R., Menta E., Oliva A., Qu Y., Farrell N. Inorg. Chem. 36:1997;3919.
7. Eastman A., Illenye S. Cancer Treat. Rep. 68:1984;1189.
8. Hacker M.P., Khokhar A.R., Brown D.B., McCormack J.J., Krakoff I.H. Cancer Res. 45:1985;4748.
9. Roberts J.D., Schmidt W.J., Tong W.P., Hacker M.P. Inorg. Chim. Acta. 153:1988;123.
10. Khan N.A., Quemener V., Moulinoux J. J. Cell Biol. Int. Rep. 15:1991;9.
11. Persson L., Holm I., Ask A., Heby O. Cancer Res. 48:1988;4807.
12. W.D.W. Heston, Cancer Surveys 11: Prostate Cancer (1991) 217.