Trifunctional dinuclear platinum complexes as DNA-protein cross-linking agents

Biochemistry

Volumn 43, Issue 24, 2004, Pages 7776-7786

  Kloster, Miriam ^a   Kostrhunova, Hana ^b   Zaludova, Renata ^b   Malina, Jaroslav ^b   Kasparkova, Jana ^b   Brabec, Viktor ^b   Farrell, Nicholas ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b INSTITUTE OF BIOPHYSICS   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; CROSSLINKING; DNA; FLUORESCENCE; PLATINUM COMPOUNDS; PROTEINS;

PALINDROMIC GENES;

BIOCHEMICAL ENGINEERING;

CHLORODIETHYLENETRIAMINEPLATINUM CHLORIDE; CISPLATIN; DNA; DNA BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE BETA; ETHIDIUM BROMIDE; KLENOW EXONUCLEASE; PALINDROMIC DNA; PLATINUM COMPLEX; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; PROTEIN; PROTEIN BAMHI; SODIUM CHLORIDE; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ARTICLE; BINDING SITE; CIRCULAR DICHROISM; COMPLEX FORMATION; COVALENT BOND; CROSS LINKING; DIFFERENTIAL PULSE POLAROGRAPHY; DNA ADDUCT; DNA CONFORMATION; DNA MODIFICATION; DNA SEQUENCE; DNA STRUCTURE; DRUG DNA BINDING; DRUG PROTEIN BINDING; DRUG TARGETING; IN VITRO STUDY; MELTING POINT; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN TARGETING; RNA TRANSCRIPTION;

CIRCULAR DICHROISM; CROSS-LINKING REAGENTS; DNA; PLATINUM COMPOUNDS; PROTEINS;

EID: 2942746524     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi030243e     Document Type: Article

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