DNA modifications by a novel bifunctional trinuclear platinum Phase I anticancer agent

Biochemistry

Volumn 38, Issue 21, 1999, Pages 6781-6790

  Brabec, Viktor ^a   Kašpárková, Jana ^a   Vrána, Oldøich ^a   Nováková, Olga ^a   Cox, John W ^b   Qu, Yun ^b   Farrell, Nicholas ^b  

^a INSTITUTE OF BIOPHYSICS   (Czech Republic)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BBR 3005; BBR 3464; CISPLATIN; CISPLATIN DERIVATIVE; PLATINUM COMPLEX; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DNA ADDUCT; DNA CROSS LINKING; DNA MODIFICATION; DNA SEQUENCE; DRUG DNA BINDING; DRUG POTENCY; DRUG STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

ANTINEOPLASTIC AGENTS; BASE SEQUENCE; BINDING SITES; BINDING SITES, ANTIBODY; BINDING, COMPETITIVE; CROSS-LINKING REAGENTS; DNA; DNA ADDUCTS; ETHIDIUM; FLUORESCENT DYES; HEAT; IMMUNOCHEMISTRY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; NUCLEIC ACID DENATURATION; ORGANOPLATINUM COMPOUNDS;

ANIMALIA;

EID: 0040610786     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990124s     Document Type: Article

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