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Volumn 43, Issue 16, 2000, Pages 3189-3192

Synthesis, characterization, and cytotoxicity of trifunctional dinuclear platinum complexes: Comparison of effects of geometry and polyfunctionality on biological activity

(6) Qu, Y a Rauter, H a Fontes, A P S a Bandarage, R a Kelland, L R b Farrell, N a

a VIRGINIA COMMONWEALTH UNIVERSITY (United States)

b INSTITUTE OF CANCER RESEARCH (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PLATINUM COMPLEX;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER; CANCER CHEMOTHERAPY; CYTOTOXICITY; DRUG DNA BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; GEOMETRY; HUMAN; HUMAN CELL;

AMINES; ANTINEOPLASTIC AGENTS; DNA, NEOPLASM; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; ORGANOMETALLIC COMPOUNDS; PLATINUM; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0034632874 PISSN: 00222623 EISSN: None Source Type: Journal
DOI: 10.1021/jm990536z Document Type: Article

Times cited : (66)

References (21)

1
- 0000561298
- Dinuclear and trinuclear platinum anticancer agents
- (1999) Uses of Inorganic Chemistry in Medicine; Farrell, N., Ed.; Royal Society of Chemistry: London , pp. 124-134
- Farrell, N.¹ Spinelli, S.²

2
- 0002606609
- Bis(platinum) complexes. Chemistry, antitumor activity and DNA-binding: Molecular basis of specificity
- Nucleic Acid-Drug Interactions; Pullman, B., Jortner, B., Eds.; Kluwer Academic: Dordrecht, The Netherlands
- (1990) , pp. 301-321
- Hoeschele, J.D.¹ Kraker, A.H.² Qu, Y.³ Van Houten, B.⁴ Farrell, N.⁵

3
- 0027080870
- Anticancer activity in murine and human tumor cell lines of bis(platinum) complexes incorporating straight-chain aliphatic diamine linker groups
- (1992) J. Med. Chem. , vol.35 , pp. 4526-4532
- Kraker, A.J.¹ Hoeschele, J.D.² Elliott, W.L.³ Showalter, H.D.⁴ Sercel, A.D.⁵ Farrell, N.P.⁶

4
- 0008667834
- Multifunctional DNA-binding metal complexes
- Topics in Biological Inorganic Chemistry; Clarke, M. J., Sadler, P. J., Eds.; Springer-Verlag: New York
- (1999) , pp. 99-115
- Farrell, N.¹ Qu, Y.² Roberts, J.D.³

5
- 0000037479
- DNA binding and chemistry of dinuclear platinum complexes
- (1994) Comments Inorg. Chem. , vol.16 , pp. 373-389
- Farrell, N.¹

6
- 0028879428
- Effects of geometric isomerism and ligand substitution in bifunctional dinuclear platinum complexes on binding properties and conformational changes in DNA
- (1995) Biochemistry , vol.34 , pp. 15480-15486
- Farrell, N.¹ Appleton, T.G.² Qu, Y.³ Roberts, J.D.⁴ Soares Fontes, A.P.⁵ Skov, K.A.⁶ Wu, P.⁷ Zou, Y.⁸

7
- 0001351573
- Structure-activity relationships within di- and trinuclear platinum phase I clinical agents
- 30 Years of Cisplatin - Chemistry and Biochemistry of a Leading Anticancer Drug; Lippert, B., Ed.; Verlag: Berlin
- (1999) , pp. 479-496
- Farrell, N.¹ Qu, Y.² Bierbach, U.³ Valsecchi, M.⁴ Menta, E.⁵

8
- 77957023153
- DNA Binding of Dinuclear Platinum Complexes Advances. DNA Sequence Specific Agents; JAI Press: Greenwich, CT
- (1996) , vol.2 , pp. 187-216
- Farrell, N.¹

9
- 0029966964
- Dinuclear platinum complexes form a novel intrastrand adduct with d(GpG) - an anti-syn conformation of the macrochelate as observed by NMR and molecular modeling
- (1996) J. Am. Chem. Soc. , vol.118 , pp. 9307-9313
- Qu, Y.¹ Bloemink, M.J.² Reedijk, J.³ Hambley, T.W.⁴ Farrell, N.⁵

10
- 0030452294
- Site-specific d(GpG) intrastrand cross-links formed by dinuclear platinum complexes. Bending and NMR studies
- (1996) Biochemistry , vol.35 , pp. 16705-16713
- Kasparkova, J.¹ Mellish, K.J.² Qu, Y.³ Brabec, V.⁴ Farrell, N.⁵

11
- 0002076397
- Methods for screening the potential antitumor activity of platinum compounds in combinatorial libraries
- 30 Years of Cisplatin - Chemistry and Biochemistry of a Leading Anticancer Drug; Lippert, B., Ed.; Verlag: Berlin
- (1999) , pp. 523-536
- Sandman, E.K.¹ Lippard, S.J.²

12
- 0008501611
- Factors affecting formation and structure of DNA intrastrand cross-links by dinuclear platinum complexes
- Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment; Hadjiliadis, N., Ed.; Kluwer Academic Publishers: London
- (1997) , vol.26 , pp. 435-439
- Qu, Y.¹ Bloemink, M.J.² Mellish, K.J.³ Rauter, H.⁴ Smeds, K.A.⁵ Farrell, N.⁶

13
- 0001615398
- Synthetic strategies for dinuclear platinum complexes containing inequivalent coordination spheres. Design of complexes capable of specific attack on one platinum center
- (1992) Inorg. Chim. Acta , pp. 123-129
- Qu, Y.¹ De Almeida, S.G.² Farrell, N.³

14
- 0000322084
- 2 units linked in a linear fashion
- (1993) Inorg. Chem. , vol.32 , pp. 2591-2593
- Qu, Y.¹ Appleton, T.G.² Hoeshele, J.D.³ Farrell, N.⁴

15
- 0001235898
- Antitumor activity of charged dinuclear platinum complexes with different coordination spheres
- (1994) Proc. AACR , vol.35 , pp. 2628
- Manzotti, C.¹ Pezzoni, G.² Giuliani, F.³ Valsecchi, M.⁴ Farrell, N.⁵ Tognella, S.⁶

16
- 0033390141
- Comparison of cytotoxicity and cellular accumulation of polynuclear platinum complexes in L1210 murine leukemia cell lines
- (1999) J. Inorg. Biochem. , vol.77 , pp. 51-57
- Roberts, J.D.¹ Peroutka, J.² Beggiolin, G.³ Manzotti, C.⁴ Piazzoni, L.⁵ Farrell, N.⁶

17
- 0027482289
- Homodinuclear (Pt,Pt) and heterodinuclear (Ru,Pt) metal compounds as DNA-protein cross-linking agents: Potential suicide DNA lesions
- (1993) Biochemistry , vol.32 , pp. 11794-11801
- Van Houten, B.¹ Illenye, S.² Qu, Y.³ Farrell, N.⁴

18
- 0008420484
- Multifunctional Homodinuclear Platinum Compounds as DNA-Protein Cross-linking Agents. 8th International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, Oxford, U.K., March 1999; Abstract 4
- (1999) , pp. 17
- Kloster, M.¹ Fontes, A.P.² Rauter, H.³ Cox, J.⁴ Qu, Y.⁵ Farrell, N.⁶

19
- 0026520306
- Human ovarian carcinoma cell lines and companion xenografts: A disease-orientated approach to new platinum anticancer drug discovery
- (1992) Cancer Chemother. Pharmacol. , vol.30 , pp. 43-50
- Kelland, L.R.¹ Jones, M.² Abel, G.³ Valenti, M.⁴ Gwynne, J.⁵ Karrap, K.R.⁶

20
- 0028143076
- A novel trans-platinum coordination complex possessing in vitro an in vivo antitumour activity
- (1994) Cancer Res , vol.54 , pp. 5618-5622
- Kelland, L.R.¹ Barnard, C.F.J.² Mellish, K.J.³ Jones, M.⁴ Goddard, P.M.⁵ Valenti, M.⁶ Bryant, A.⁷ Murrer, B.A.⁸ Harrap, K.R.⁹

21
- 0025341331
- New colorimetric cytotoxicity assay for anticancer drug screening
- (1990) J. Natl. Cancer Inst. , vol.82 , pp. 1107-1112
- Skehan, P.¹ Storeng, R.² Scudiero, D.³ Monks, A.⁴ Mcmahon, J.⁵ Visitica, D.⁶ Warren, J.⁷ Bokesch, H.⁸ Kennedy, S.⁹ Boyd, M.R.¹⁰

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