-
2
-
-
0035895505
-
The sequence of the human genome
-
Venter J C, Adams M D, Myers E W, Li P W, Mural R J, Sutton G G, Smith H O, Yandell M, Evans C A, Holt R A, Gocayne J D, Amanatides P, Ballew R M & Huson D H et al., The sequence of the human genome, Science, 291 (2001) 1304-1351.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
Smith, H.O.7
Yandell, M.8
Evans, C.A.9
Holt, R.A.10
Gocayne, J.D.11
Amanatides, P.12
Ballew, R.M.13
Huson, D.H.14
-
3
-
-
0036137613
-
An integrated approach for finding overlooked genes in yeast
-
Kumar A, Harrison P M, Cheung K-H, Lan N, Echols N, Bertone P, Miller P, Gerstein M B & Snyder M, An integrated approach for finding overlooked genes in yeast, Nature Biotechnol, 20 (2002) 58-63.
-
(2002)
Nature Biotechnol
, vol.20
, pp. 58-63
-
-
Kumar, A.1
Harrison, P.M.2
Cheung, K.-H.3
Lan, N.4
Echols, N.5
Bertone, P.6
Miller, P.7
Gerstein, M.B.8
Snyder, M.9
-
4
-
-
0036175276
-
The past, present and future of genome, wide re- annatation
-
Comment 2001.1 - comment 2110.6
-
Ouzounis C A & Karp P D, The past, present and future of genome, wide re- annatation, Genome Biol, Comment (2002) 2001.1 - comment 2110.6
-
(2002)
Genome Biol
-
-
Ouzounis, C.A.1
Karp, P.D.2
-
5
-
-
0035132121
-
-
David Bentley interviewed by Rebecca Lawrence
-
David Bentley interviewed by Rebecca Lawrence, Drug Discovery Today, 6(1) (2001) 13.
-
(2001)
Drug Discovery Today
, vol.6
, Issue.1
, pp. 13
-
-
-
6
-
-
0037101902
-
Integrating diagnostics and therapeutics" Revolutionizing drug discovery and patient care
-
Ross J S & Ginsburg G S, Integrating diagnostics and therapeutics" revolutionizing drug discovery and patient care. Drug Discovery Today, 7(16) (2002) 859-864.
-
(2002)
Drug Discovery Today
, vol.7
, Issue.16
, pp. 859-864
-
-
Ross, J.S.1
Ginsburg, G.S.2
-
7
-
-
0000803821
-
A novel bifunctional fluorescent tag for use in molecular biology
-
Dubey K K, Singh R K & Misra K, A novel bifunctional fluorescent tag for use in molecular biology, Indian J Chem, 34B (1995) 876-78.
-
(1995)
Indian J Chem
, vol.34 B
, pp. 876-878
-
-
Dubey, K.K.1
Singh, R.K.2
Misra, K.3
-
9
-
-
0036290164
-
Synthesis, characterisation and fluorescence study of some novel naphthalimide derivatives
-
Singh Y, Misra A & Misra K, Synthesis, characterisation and fluorescence study of some novel naphthalimide derivatives, Indian J Chem, 41B (6) (2002) 1238-1345.
-
(2002)
Indian J Chem
, vol.41 B
, Issue.6
, pp. 1238-1345
-
-
Singh, Y.1
Misra, A.2
Misra, K.3
-
10
-
-
0029434489
-
Fluorophores for labeling of DNA/RNA fragments
-
Dubey K K, P Kumar P, Singh R K & Misra K, Fluorophores for labeling of DNA/RNA fragments, Nucl Acids Symp Ser, 34 (1995) 177-78.
-
(1995)
Nucl Acids Symp Ser
, vol.34
, pp. 78-177
-
-
Dubey, K.K.1
Kumar, P.P.2
Singh, R.K.3
Misra, K.4
-
11
-
-
7844230307
-
Modified oligonucleotides as fluorescent probes
-
Pandey R K, Dubey K K, Misra K & R K Singh, Modified oligonucleotides as fluorescent probes, Nucl Acids Symp Ser, 35 (1996) 199-200.
-
(1996)
Nucl Acids Symp Ser
, vol.35
, pp. 199-200
-
-
Pandey, R.K.1
Dubey, K.K.2
Misra, K.3
Singh, R.K.4
-
12
-
-
0031758714
-
Synthesis and hybridisation studies of oligonucleotide sequences with modified fluorescent nucleoside analogs
-
Pandey R K, Tripathi S & Misra K, Synthesis and hybridisation studies of oligonucleotide sequences with modified fluorescent nucleoside analogs, Nucleoside Nucleotide, 17 (1998) 9 - 11.
-
(1998)
Nucleoside Nucleotide
, vol.17
, pp. 9-11
-
-
Pandey, R.K.1
Tripathi, S.2
Misra, K.3
-
13
-
-
1842696429
-
An efficient and cost-effective strategy for selective N-acylation of purine and pyrimidine bases of deoxy and ribo nucleosides
-
Communicated
-
Tripathi S, Mishra R, Misra K & Yogesh S Sanghvi, An efficient and cost-effective strategy for selective N-acylation of purine and pyrimidine bases of deoxy and ribo nucleosides, Nucl Acids Res, (2003) (Communicated).
-
(2003)
Nucl Acids Res
-
-
Tripathi, S.1
Mishra, R.2
Misra, K.3
Sanghvi, Y.S.4
-
14
-
-
1842696430
-
Process for selective N- acylation of purine nucleosides
-
Aril 01
-
Tripathi S, Misra K & Yogesh S Sanghvi, Process for selective N- acylation of purine nucleosides, U S Pat No. 6, 541, 626 B2, Aril 01, 2003.
-
(2003)
U S Pat No. 6, 541, 626 B2
-
-
Tripathi, S.1
Misra, K.2
Sanghvi, Y.S.3
-
15
-
-
0034659898
-
Genomics, gene expression and DNA- arrays
-
Lockhart D J & Winzerler E A, Genomics, gene expression and DNA- arrays, Nature, 405 (2000) 827-836.
-
(2000)
Nature
, vol.405
, pp. 827-836
-
-
Lockhart, D.J.1
Winzerler, E.A.2
-
16
-
-
0035378234
-
Micro arrays: Lost in a storm of data?
-
Miles M F, Micro arrays: lost in a storm of data?, Nat Rev Neurosci, 2 (2001) 441-443.
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 441-443
-
-
Miles, M.F.1
-
17
-
-
0028073794
-
BRCA1 mutations in primary breast and ovarian carcinomas
-
Futreal PA, Liu Q, Shattuck-Eidens D, Cochran C, Harshman K, Tavtigian S, Bennett L M, Haugen-Strano A, Swensen J, Miki Y et al, BRCA1 mutations in primary breast and ovarian carcinomas, Science, 266 (1994) 120-122.
-
(1994)
Science
, vol.266
, pp. 120-122
-
-
Futreal, P.A.1
Liu, Q.2
Shattuck-Eidens, D.3
Cochran, C.4
Harshman, K.5
Tavtigian, S.6
Bennett, L.M.7
Haugen-Strano, A.8
Swensen, J.9
Miki, Y.10
-
18
-
-
0028006563
-
Localization of a breast cancer susceptibility gene, BRCA2 to chromosome Bq 12-13
-
Wooster R, Neuhausen S L, Mangion J, Quirk Y, Ford D, Collins N, Nguyen K, Seal S, Tran T, Averill D et al., Localization of a breast cancer susceptibility gene, BRCA2 to chromosome Bq 12-13, Science, 265 (1994) 2088-2090.
-
(1994)
Science
, vol.265
, pp. 2088-2090
-
-
Wooster, R.1
Neuhausen, S.L.2
Mangion, J.3
Quirk, Y.4
Ford, D.5
Collins, N.6
Nguyen, K.7
Seal, S.8
Tran, T.9
Averill, D.10
-
19
-
-
0035978651
-
Association of NoD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot J P, Chamaillard M, Zouali H, Lesage S, Cézard J-P, Belaiche J, Almer S, Tysk S, O'Morain C A, Gassull M, Binder V, Finkel Y, Cortot A, Modigliani R, Laurent-Pug P, Gowe-Rousseac C, Macry J, Colombel J-F, Sahbatou M & Thomas G, Association of NoD2 leucine-rich repeat variants with susceptibility to Crohn's disease, Nature, 411 (2001) 599-603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cézard, J.-P.5
Belaiche, J.6
Almer, S.7
Tysk, S.8
O'Morain, C.A.9
Gassull, M.10
Binder, V.11
Finkel, Y.12
Cortot, A.13
Modigliani, R.14
Laurent-Pug, P.15
Gowe-Rousseac, C.16
Macry, J.17
Colombel, J.-F.18
Sahbatou, M.19
Thomas, G.20
more..
-
20
-
-
1842797252
-
Genetic analysis of immunological disease in the mouse by RNAi
-
(Hynes Convention Center, Boston M A) (12 August)
-
Parijs L V, Genetic analysis of immunological disease in the mouse by RNAi, Drug Discovery Ser; IBC's Second Annu Model Organism Drug Discovery, (Hynes Convention Center, Boston M A) (12 August 2003).
-
(2003)
Drug Discovery Ser; IBC's Second Annu Model Organism Drug Discovery
-
-
Parijs, L.V.1
-
21
-
-
0033852468
-
A mouse phenome project
-
Paigen K & Eppig J T, A mouse phenome project, Mann Genome, 11 (2000) 715-717.
-
(2000)
Mann Genome
, vol.11
, pp. 715-717
-
-
Paigen, K.1
Eppig, J.T.2
-
22
-
-
1842646007
-
Deductive Genomes: Industrializing discovery biology and target validation using the mouse models
-
(Hynes Convention Center, Boston M A) (13 August)
-
Nehls M C, Deductive Genomes: Industrializing discovery biology and target validation using the mouse models, Drug Discovery Ser; IBC's Second Annu Model Organism Drug Discovey (Hynes Convention Center, Boston M A) (13 August 2003).
-
(2003)
Drug Discovery Ser; IBC's Second Annu Model Organism Drug Discovey
-
-
Nehls, M.C.1
-
23
-
-
1842696377
-
Development and characterisation of mouse models for complex diseases
-
(Hynes Convention Center, Boston M A) (13 August)
-
Glynn R, Development & characterisation of mouse models for complex diseases, Drug Discovery Ser; IBC's Second Annu Model Organism Drug Discovery, (Hynes Convention Center, Boston M A) (13 August 2003).
-
(2003)
Drug Discovery Ser; IBC's Second Annu Model Organism Drug Discovery
-
-
Glynn, R.1
-
25
-
-
0036525710
-
Human tissue in target identification and drug discovery
-
Palfreyman M G, Human tissue in target identification and drug discovery, Drug Discovery Today, 7(7) (2002) 407.
-
(2002)
Drug Discovery Today
, vol.7
, Issue.7
, pp. 407
-
-
Palfreyman, M.G.1
-
26
-
-
0037088998
-
Transgenic system in drug discovery from target identification to humanized mice
-
Tornell J & Snaith M, Transgenic system in drug discovery from target identification to humanized mice, Drug Discovery Today, 7(8) (2002) 461.
-
(2002)
Drug Discovery Today
, vol.7
, Issue.8
, pp. 461
-
-
Tornell, J.1
Snaith, M.2
-
28
-
-
0242568295
-
Germ line integration and mendelian transmission of the exogenous Moloney leukemia virus
-
Jacnisch R, Germ line integration and mendelian transmission of the exogenous Moloney leukemia virus, Proc Natl Acad Sci USA, 73 (1976) 1260-1264.
-
(1976)
Proc Natl Acad Sci USA
, vol.73
, pp. 1260-1264
-
-
Jacnisch, R.1
-
29
-
-
0019847283
-
Genetic transformation of mouse embryos by microinjection of purified DNA
-
Gordon J W & Ruddle F H, Genetic transformation of mouse embryos by microinjection of purified DNA, Science, 214 (1981) 1244-1246.
-
(1981)
Science
, vol.214
, pp. 1244-1246
-
-
Gordon, J.W.1
Ruddle, F.H.2
-
30
-
-
0020470466
-
Dramatic growth of mice that develop from eggs microinjected with metallothionein growth hormone fusion genes
-
Palmiter R D, Brinster R L, Hammer R E, Trumbauer M E, Rosenfeld M G, Birnberg N C & Evans R M, Dramatic growth of mice that develop from eggs microinjected with metallothionein growth hormone fusion genes. Nature, 300 (1982) 611-615.
-
(1982)
Nature
, vol.300
, pp. 611-615
-
-
Palmiter, R.D.1
Brinster, R.L.2
Hammer, R.E.3
Trumbauer, M.E.4
Rosenfeld, M.G.5
Birnberg, N.C.6
Evans, R.M.7
-
31
-
-
0028931102
-
CpG motif bacterial DNA trigger direct β - cell activation
-
Kreig A M, Yi A-K, Matson S, Waldschmidt T J, Bishop G A, Teasdale R, Koretsky G A & Klinman D M, CpG motif bacterial DNA trigger direct β - cell activation, Nature, 374 (1995) 546-549.
-
(1995)
Nature
, vol.374
, pp. 546-549
-
-
Kreig, A.M.1
Yi, A.-K.2
Matson, S.3
Waldschmidt, T.J.4
Bishop, G.A.5
Teasdale, R.6
Koretsky, G.A.7
Klinman, D.M.8
-
32
-
-
0041582974
-
Inhibition of Rous sarcoma virus replication and cell transformation by specific oligodeoxynucleotide
-
Zamecnik P C & Stephenson M L, Inhibition of Rous sarcoma virus replication and cell transformation by specific oligodeoxynucleotide, Proc Natl Acad Sci USA, 75 (1978) 80-284.
-
(1978)
Proc Natl Acad Sci USA
, vol.75
, pp. 80-284
-
-
Zamecnik, P.C.1
Stephenson, M.L.2
-
33
-
-
0035709416
-
Functional genomics and target validation approach using antisense oligonucleotide technology
-
Dean N M, Functional genomics and target validation approach using antisense oligonucleotide technology, Curr Opin Biotechnol, 12 (2001) 622-625.
-
(2001)
Curr Opin Biotechnol
, vol.12
, pp. 622-625
-
-
Dean, N.M.1
-
34
-
-
0036742715
-
Application of antisense and si RNAs during preclinical drug development
-
Thompson J D, Application of antisense and si RNAs during preclinical drug development, Drug Discovery Today, 7(17) (2002) 912-917.
-
(2002)
Drug Discovery Today
, vol.7
, Issue.17
, pp. 912-917
-
-
Thompson, J.D.1
-
35
-
-
0032817254
-
An antisense oligonucleotide primer
-
Hogrefe R I, An antisense oligonucleotide primer, Antisense Nucl Acid Drug Dev, 9 (1999) 351-357
-
(1999)
Antisense Nucl Acid Drug Dev
, vol.9
, pp. 351-357
-
-
Hogrefe, R.I.1
-
36
-
-
0034853258
-
Discovery and analysis of antisense oligonucleotide activity in cell culture
-
Baker B F, Condon T P, Koller E, Mackay R A, Siwkouski A M, Vickers T A & Monia B P, Discovery and analysis of antisense oligonucleotide activity in cell culture, Methods, 23 (2001) 191-198.
-
(2001)
Methods
, vol.23
, pp. 191-198
-
-
Baker, B.F.1
Condon, T.P.2
Koller, E.3
Mackay, R.A.4
Siwkouski, A.M.5
Vickers, T.A.6
Monia, B.P.7
-
37
-
-
0010565064
-
Sequencing - selective recognition of DNA by stand displacement with a thymine- substituted polyamide
-
Neilsen P E et al., Sequencing - selective recognition of DNA by stand displacement with a thymine- substituted polyamide, Cancer Res, 15 (1991) 5468-5473.
-
(1991)
Cancer Res
, vol.15
, pp. 5468-5473
-
-
Neilsen, P.E.1
-
38
-
-
0034939942
-
Phosphorodiamidate morpholino oligomers: Favorable properties for sequence- specific gene inactivation
-
Inversen P L, Phosphorodiamidate morpholino oligomers: Favorable properties for sequence- specific gene inactivation, Curr Opin Mol Ther, 3 (2001) 235-238.
-
(2001)
Curr Opin Mol Ther
, vol.3
, pp. 235-238
-
-
Inversen, P.L.1
-
39
-
-
0034938693
-
Locked Nucleic acids: A promising molecular family for gene function analysis and antisense drug development
-
Orum H & Wengel J, Locked Nucleic acids: a promising molecular family for gene function analysis and antisense drug development, Curr Opin Mol Ther, 3 (2001) 239-243.
-
(2001)
Curr Opin Mol Ther
, vol.3
, pp. 239-243
-
-
Orum, H.1
Wengel, J.2
-
40
-
-
0031027349
-
In vivo studies with antisense oligonucleotide
-
Akhtar S & Agrawal S, In vivo studies with antisense oligonucleotide, Trends Pharmacol Sci, 18 (1997) 12-18.
-
(1997)
Trends Pharmacol Sci
, vol.18
, pp. 12-18
-
-
Akhtar, S.1
Agrawal, S.2
-
43
-
-
0042388311
-
Immunostimulation, the sense in antisense technology
-
Pandey A, Mishra S & Misra K, Immunostimulation, the sense in antisense technology, Indian J Biotechnol, 2 (2) (2003) 175-183.
-
(2003)
Indian J Biotechnol
, vol.2
, Issue.2
, pp. 175-183
-
-
Pandey, A.1
Mishra, S.2
Misra, K.3
-
44
-
-
0037462875
-
CpG penta and hexadeoxyribonucleotides as potent immunomodulatory agents
-
Bhagat L, Zhu F- G, Yu D, Tang J, Wang H, Kandimallla E R, Zhang R & Agrawal S, CpG penta & hexadeoxyribonucleotides as potent immunomodulatory agents, Biomed Biophys Res Commun, 300 (2003) 853-861.
-
(2003)
Biomed Biophys Res Commun
, vol.300
, pp. 853-861
-
-
Bhagat, L.1
Zhu F-, G.2
Yu, D.3
Tang, J.4
Wang, H.5
Kandimallla, E.R.6
Zhang, R.7
Agrawal, S.8
-
45
-
-
0037295379
-
Requirement of nucleobase proximal to CpG dinucleotide for immunoistimulatory activity of synthetic CpG DNA
-
Yu D, Kandimalla E R, Zhao Q, Bhagat L, Cong Y & Agrawal S, Requirement of nucleobase proximal to CpG dinucleotide for immunoistimulatory activity of synthetic CpG DNA, Bioorg Med Chem, 11 (2003) 459-464.
-
(2003)
Bioorg Med Chem
, vol.11
, pp. 459-464
-
-
Yu, D.1
Kandimalla, E.R.2
Zhao, Q.3
Bhagat, L.4
Cong, Y.5
Agrawal, S.6
-
46
-
-
1842696375
-
Mechanism and applications of immunoistimulatory CpG oligos
-
(Mandalay Bay Resort and Casino, Las Vegas N V) April 30- May 2
-
Uhlmann E, Mechanism & applications of immunoistimulatory CpG oligos, Nucleic acids in drug discovery, innovations in tools and targets (Mandalay Bay Resort and Casino, Las Vegas N V) April 30- May 2 2003.
-
(2003)
Nucleic Acids in Drug Discovery, Innovations in Tools and Targets
-
-
Uhlmann, E.1
-
47
-
-
1842746759
-
Antisense approach for chemotherapy of some viral diseases
-
Review
-
Tiwari A and Misra K, Antisense approach for chemotherapy of some viral diseases (Review), Ann Neurosci, 3 (1992) 1-11.
-
(1992)
Ann Neurosci
, vol.3
, pp. 1-11
-
-
Tiwari, A.1
Misra, K.2
-
49
-
-
0032545933
-
Potent and specific genetic interference by double stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S Q, Montgomery M K, Kostas S A, Driver S E, Mello C C, Potent and specific genetic interference by double stranded RNA in Caenorhabditis elegans, Nature, 391 (1998) 806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, Q.2
Montgomery, M.K.3
Kostas, A.4
Driver, S.E.5
Mello, C.C.6
-
50
-
-
0029024475
-
Par-I, A gene required for establishing polarity in C. Elegans embryos, encodes a putative Ser/ Thr Kinase is asymmetrically distributed
-
Guo S & Kemphues K J, Par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/ Thr Kinase is asymmetrically distributed, Cell, 81 (1995) 611-620.
-
(1995)
Cell
, vol.81
, pp. 611-620
-
-
Guo, S.1
Kemphues, K.J.2
-
51
-
-
0037107886
-
RNAi: Gene silencing in therapeutic intervention
-
Shuey D J, McCallus, D E & Giordano T, RNAi: gene silencing in therapeutic intervention, Drug Discovery Today, 7(20) (2002) 1040-1046.
-
(2002)
Drug Discovery Today
, vol.7
, Issue.20
, pp. 1040-1046
-
-
Shuey, D.J.1
McCallus, D.E.2
Giordano, T.3
-
53
-
-
0035863097
-
NA interference is mediated by 21 and 22- nucleotide RNAs
-
Elbashir S M, Lendeckel W & Tuschl T, NA interference is mediated by 21 and 22- nucleotide RNAs, Genes Dev, 15 (2001) 188-200.
-
(2001)
Genes Dev
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
54
-
-
0037123639
-
RNA depended RNA polmerases, viruses, and RNA Silencing
-
Ahlquist P, RNA depended RNA polmerases, viruses, and RNA Silencing, Science, 296 (2002) 1270-1273.
-
(2002)
Science
, vol.296
, pp. 1270-1273
-
-
Ahlquist, P.1
-
55
-
-
0034737298
-
RNAi: Double stranded RNA directs the ATP- dependent cleavage of mRNA at 21-to 23 nucleotide interval
-
Zamore P D, Tuschl T, Sharp P A & Bartel D P, RNAi: double stranded RNA directs the ATP- dependent cleavage of mRNA at 21-to 23 nucleotide interval, Cell, 101 (2000) 25-33.
-
(2000)
Cell
, vol.101
, pp. 25-33
-
-
Zamore, P.D.1
Tuschl, T.2
Sharp, P.A.3
Bartel, D.P.4
-
56
-
-
0037197914
-
RNA interference by expression of short interfering RNAs and hairpin RNAs in mammalian Cells
-
Yu J Y, DeRuiter S L, & Turner D L, RNA interference by expression of short interfering RNAs and hairpin RNAs in mammalian Cells, Proc Natl Acad Sci USA, 99 (2002) 6047-6052.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6047-6052
-
-
Yu, J.Y.1
DeRuiter, S.L.2
Turner, D.L.3
-
57
-
-
0035798399
-
RNAi as random degradative PCR; siRNA primers convert mRNA into dsRNAs that are degraded to generate new si RNAs
-
Lipardi C, Wei O, & Paterson B M, RNAi as random degradative PCR; siRNA primers convert mRNA into dsRNAs that are degraded to generate new si RNAs, Cell, 107 (2001) 297-307.
-
(2001)
Cell
, vol.107
, pp. 297-307
-
-
Lipardi, C.1
Wei, O.2
Paterson, B.M.3
-
58
-
-
0037012907
-
Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila
-
Dobrosotskaya I Y, Seegmiller A C, Brown M S, Goldstein J L & Rawson R B, Regulation of SREBP Processing and membrane lipid production by phospholipids in Drosophila, Science, 296 (2002) 879-883.
-
(2002)
Science
, vol.296
, pp. 879-883
-
-
Dobrosotskaya, I.Y.1
Seegmiller, A.C.2
Brown, M.S.3
Goldstein, J.L.4
Rawson, R.B.5
-
59
-
-
0037448540
-
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
-
Kamath R S, Fraser A G, Dong, Y, Poulin G, Durbin R, Gotta M, Kanapin A, Bot N L, Moreno S, Sohrmonn M, Welchman D P, Zipperlen P & Ahringer J, Systematic functional analysis of the Caenorhabditis elegans genome using RNAi, Nature, 421 (2003) 231-237.
-
(2003)
Nature
, vol.421
, pp. 231-237
-
-
Kamath, R.S.1
Fraser, A.G.2
Dong, Y.3
Poulin, G.4
Durbin, R.5
Gotta, M.6
Kanapin, A.7
Bot, N.L.8
Moreno, S.9
Sohrmonn, M.10
Welchman, D.P.11
Zipperlen, P.12
Ahringer, J.13
-
60
-
-
0036351317
-
Analysis of gene function in somatic mammalian cells using small interfering RNAs
-
Elabashir S M, Harborth J, Weber K & Tuschl T, Analysis of gene function in somatic mammalian cells using small interfering RNAs, Methods, 26 (2002) 199-213.
-
(2002)
Methods
, vol.26
, pp. 199-213
-
-
Elabashir, S.M.1
Harborth, J.2
Weber, K.3
Tuschl, T.4
-
61
-
-
0036251639
-
Effective expression of small interfering RNA in human cells
-
Paul C P, Good P D, Winer I & Engelke D R, Effective Expression of small interfering RNA in human cells Nature Biotechnol, 20 (2002) 505-508.
-
(2002)
Nature Biotechnol
, vol.20
, pp. 505-508
-
-
Paul, C.P.1
Good, P.D.2
Winer, I.3
Engelke, D.R.4
-
62
-
-
0012756249
-
RNA interference in mammalian cells using siRNA synthesized with T7 RNA polymerase
-
Donze O & Picard D, RNA interference in mammalian cells using siRNA synthesized with T7 RNA polymerase. Nucl Acids Res, 30 (2002) c 46.
-
(2002)
Nucl Acids Res
, vol.30
-
-
Donze, O.1
Picard, D.2
-
63
-
-
0037022382
-
Stable suppression of gene expression by RNAi in mammalian cells
-
Paddison P J, Caudy A A & Hannon G J, Stable suppression of gene expression by RNAi in mammalian cells, Proc Natl Acad Sci USA, 99 (2002) 1443-1448.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 1443-1448
-
-
Paddison, P.J.1
Caudy, A.A.2
Hannon, G.J.3
-
64
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp T R, Bernards R, & Agami R, A system for stable expression of short interfering RNAs in mammalian cells, Science, 296 (2002) 550-553.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
65
-
-
0036256430
-
Expression of small interfering RNAs targeted against HIV- I rev Transcripts in human cells
-
Lee N S, Dohjima T, Bauer G, Li H, Li M-J, Ehsani A, Salvaterra P & Rossi J, Expression of small interfering RNAs targeted against HIV- I rev. Transcripts in human cells. Nat Biotechnol, 19 (2002) 500-505.
-
(2002)
Nat Biotechnol
, vol.19
, pp. 500-505
-
-
Lee, N.S.1
Dohjima, T.2
Bauer, G.3
Li, H.4
Li, M.-J.5
Ehsani, A.6
Salvaterra, P.7
Rossi, J.8
-
66
-
-
0035900651
-
On tire role of RNA amplification in ds RNA- triggered gene silencing
-
Sijen T, Fleenor J, Simmer F, Thijssen K L, Parrish S, Timmons L, Plasterk R H A, & Fire A, On tire role of RNA amplification in ds RNA- triggered gene Silencing, Cell, 107 (2001) 465-476.
-
(2001)
Cell
, vol.107
, pp. 465-476
-
-
Sijen, T.1
Fleenor, J.2
Simmer, F.3
Thijssen, K.L.4
Parrish, S.5
Timmons, L.6
Plasterk, R.H.A.7
Fire, A.8
-
67
-
-
1842797244
-
Genome- wide RNAi analysis of (elegans fat regulatory genes)
-
Mandalay Bay Resort and Casino Las Vegas, NV, USA April 28-May 1
-
Vargeese C, Ahringer J & Ruvkum G, Genome- wide RNAi analysis of (elegans fat regulatory genes) TIDES-oligonucleotide and peptide technology conference (Mandalay Bay Resort and Casino Las Vegas, NV, USA) (April 28-May 1, 2003).
-
(2003)
TIDES-oligonucleotide and Peptide Technology Conference
-
-
Vargeese, C.1
Ahringer, J.2
Ruvkum, G.3
-
69
-
-
0019856947
-
In vitro splicing of the ribosomal RNA precursor of Tetrahymena; Involvement of a guanosine nucleotide in the excision of the intervening sequence
-
Cech R, Zaug A J & Grabowski P J, In vitro splicing of the ribosomal RNA precursor of Tetrahymena; Involvement of a guanosine nucleotide in the excision of the intervening sequence, Cell, 29 1981) 487.
-
(1981)
Cell
, vol.29
, pp. 487
-
-
Cech, R.1
Zaug, A.J.2
Grabowski, P.J.3
-
70
-
-
0021013526
-
The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
-
Guerrier- Takada C, Gardiner K, Marsh T, Pace N & Altman S, The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme, Cell, 35 (1983) 849-857.
-
(1983)
Cell
, vol.35
, pp. 849-857
-
-
Guerrier- Takada, C.1
Gardiner, K.2
Marsh, T.3
Pace, N.4
Altman, S.5
-
71
-
-
0036818502
-
Ribozymes- a new approach for modeling gene expression
-
Singh Y, Misra A, Tripathi S & Misra K, Ribozymes- a new approach for modeling gene expression. J Sci Ind Res, 61 (2002) 775-785.
-
(2002)
J Sci Ind Res
, vol.61
, pp. 775-785
-
-
Singh, Y.1
Misra, A.2
Tripathi, S.3
Misra, K.4
-
72
-
-
0037062920
-
Emerging clinical applications of RNA
-
Sullenger B A & Gilboa E, Emerging clinical applications of RNA, Nature, 418 (2002) 252-258.
-
(2002)
Nature
, vol.418
, pp. 252-258
-
-
Sullenger, B.A.1
Gilboa, E.2
-
73
-
-
0033692912
-
Nuclease resistant synthetic ribozymes; developing a new class of therapeutics
-
Usman N & Blatt L M, Nuclease resistant synthetic ribozymes; developing a new class of therapeutics, J Clin Invest, 106 (2000) 1197-1202.
-
(2000)
J Clin Invest
, vol.106
, pp. 1197-1202
-
-
Usman, N.1
Blatt, L.M.2
-
74
-
-
0033198914
-
A phase 1 trail of autologous CD34+ hematopoietic progenitor cells transduced with an anti- HIV ribozyme
-
Amado R G, Mitsuyasu R T, Symonds G, Rosenblatt J D, Zack J, Sun L-Q & Miller M A phase 1 trail of autologous CD34+ hematopoietic progenitor cells transduced with an anti- HIV ribozyme, Hum Gen Ther, 10 (1999) 2255-2270.
-
(1999)
Hum Gen Ther
, vol.10
, pp. 2255-2270
-
-
Amado, R.G.1
Mitsuyasu, R.T.2
Symonds, G.3
Rosenblatt, J.D.4
Zack, J.5
Sun, L.-Q.6
Miller, M.7
-
75
-
-
0033692912
-
Nuclease resistant synthetic ribozymes; developing a new class of therapeutics
-
Usman N and Blatt L M, Nuclease resistant synthetic ribozymes; developing a new class of therapeutics, J Clin Invest, 106 (2000) 1197-1202.
-
(2000)
J Clin Invest
, vol.106
, pp. 1197-1202
-
-
Usman, N.1
Blatt, L.M.2
-
76
-
-
0034069028
-
Antitumor and antimetastatic activity of ribozyme targeting the m RNA of vascular endothelial growth factor receptor
-
Pavco P A, Bouhana K S, Gallegos A M, Agrawal A, Blanchard K S, Grimm S L, Jensen K L, Andrews L E, Wincott F E, Pitot P A, Tressler R J, Cushman C, Reynolds M A & Parry T J, Antitumor and antimetastatic activity of ribozyme targeting the m RNA of vascular endothelial growth factor receptor, Clin Cancer Res, 6 (2000) 2094-2103.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2094-2103
-
-
Pavco, P.A.1
Bouhana, K.S.2
Gallegos, A.M.3
Agrawal, A.4
Blanchard, K.S.5
Grimm, S.L.6
Jensen, K.L.7
Andrews, L.E.8
Wincott, F.E.9
Pitot, P.A.10
Tressler, R.J.11
Cushman, C.12
Reynolds, M.A.13
Parry, T.J.14
-
77
-
-
0035989626
-
RNA as the catalyst for drug screening
-
Gold L, RNA as the catalyst for drug screening, Nature Biotechnol, 20 (2002), 671-672.
-
(2002)
Nature Biotechnol
, vol.20
, pp. 671-672
-
-
Gold, L.1
-
78
-
-
0035989643
-
-
Hartig, J S, Najafi-Shoushtari S H, Grüne I, Yan A, Ellington A D & Famulok M, Nature Biotechnol, 20 (2002) 717-722.
-
(2002)
Nature Biotechnol
, vol.20
, pp. 717-722
-
-
Hartig, J.S.1
Najafi-Shoushtari, S.H.2
Grüne, I.3
Yan, A.4
Ellington, A.D.5
Famulok, M.6
-
79
-
-
1842746747
-
Developing allosteric ribozymes for diagnostic
-
(Mandalay Bay Resort and Casino, Las Vegas, NV) April 30- May 2
-
Seiwert S, Developing allosteric ribozymes for diagnostic, Nucleic acids discoveries-innovations in tools and targets (Mandalay Bay Resort and Casino, Las Vegas, NV) (April 30- May 2) 2003.
-
(2003)
Nucleic Acids Discoveries-Innovations in Tools and Targets
-
-
Seiwert, S.1
-
81
-
-
0037092191
-
Chip, chip array! Three chips for post genomic research
-
Rockett J C, Chip, chip array! Three chips for post genomic research, Drug Discovery Today, 7(8) (2002) 458-459.
-
(2002)
Drug Discovery Today
, vol.7
, Issue.8
, pp. 458-459
-
-
Rockett, J.C.1
-
82
-
-
0033569406
-
Molecular classification of cancer: Class discovery and class prediction by gene expression profiling
-
Golub T R, Slonim D K, Tamayo P, Huard C, Gaasenbeek M, Mesirov J P, Coller H, Loh M L, Downing J R, Caligiuri M A, Bloomfield C D, & Lander E S, Molecular classification of cancer: class discovery and class prediction by gene expression profiling, Science, 286 (1999) 531-537.
-
(1999)
Science
, vol.286
, pp. 531-537
-
-
Golub, T.R.1
Slonim, K.2
Tamayo, P.3
Huard, C.4
Gaasenbeek, M.5
Mesirov, J.P.6
Coller, H.7
Loh, M.L.8
Downing, J.R.9
Caligiuri, M.A.10
Bloomfield, C.D.11
Lander, E.S.12
-
83
-
-
18344396568
-
Minimum information about a microarray experiment (MIAME) - towards standards for microarray data
-
Brazma A, Hingamp P, Quackenbush J, Sherlock G, Spellman P, Stoeckert C, Aach J, Ansorge W, Ball C A, Causton H C, Wasteland T, Glenisson P, HolstegeF C P, Kim I F, Markowitz V, Matese J C, Parkinson H, Robinson A, Sarkans U, Schulze-Kremer S, Stewart J, Taylor R, Vilo J, & Vingron M, Minimum information about a microarray experiment (MIAME) - towards standards for microarray data. Nat Genet, 29 (2001) 365-371.
-
(2001)
Nat Genet
, vol.29
, pp. 365-371
-
-
Brazma, A.1
Hingamp, P.2
Quackenbush, J.3
Sherlock, G.4
Spellman, P.5
Stoeckert, C.6
Aach, J.7
Ansorge, W.8
Ball, C.A.9
Causton, H.C.10
Wasteland, T.11
Glenisson, P.12
Holstege, F.C.P.13
Kim, I.F.14
Markowitz, V.15
Matese J.C16
Parkinson, H.17
Robinson, A.18
Sarkans, U.19
Schulze-Kremer, S.20
Stewart, J.21
Taylor, R.22
Vilo, J.23
Vingron, M.24
more..
-
84
-
-
0036489209
-
Current themes in microarray experimental design and analysis
-
Foster W R & Huber R M, Current themes in microarray experimental design and analysis, Drug Discovery Today, 7(5) (2002) 290-292.
-
(2002)
Drug Discovery Today
, vol.7
, Issue.5
, pp. 290-292
-
-
Foster, W.R.1
Huber, R.M.2
-
85
-
-
0037096219
-
Chip based diagnostics for meningitis and food poisoning
-
Clayton J, Chip based diagnostics for meningitis and food poisoning, Drug Discovery Today, 7(12) (2002) 637-638.
-
(2002)
Drug Discovery Today
, vol.7
, Issue.12
, pp. 637-638
-
-
Clayton, J.1
-
86
-
-
0037129228
-
Biodiversity; microbial genomes multiply
-
Doolittle R F, Biodiversity; microbial genomes multiply, Nature, 416 (2002) 697-700.
-
(2002)
Nature
, vol.416
, pp. 697-700
-
-
Doolittle, R.F.1
-
87
-
-
0037443710
-
Of mouse and man- what is the value of the mouse in predicting gene expression in human
-
Coleman R A, Of mouse & man- what is the value of the mouse in predicting gene expression in human, Drug Discovery Today, 8(6) (2003) 233-235.
-
(2003)
Drug Discovery Today
, vol.8
, Issue.6
, pp. 233-235
-
-
Coleman, R.A.1
-
88
-
-
0035971103
-
DNA arrays-Aftymetrix settles suit, fixes chips
-
Marshall E, DNA arrays-Aftymetrix settles suit, fixes chips, Science, 291 (2001) 2535.
-
(2001)
Science
, vol.291
, pp. 2535
-
-
Marshall, E.1
-
89
-
-
0024836381
-
Isolation and characterization of multipotent clone of human embryonal carcinoma cells
-
Pera M E et al., Isolation and characterization of multipotent clone of human embryonal carcinoma cells, Differentiation, 42 (1989) 10-23.
-
(1989)
Differentiation
, vol.42
, pp. 10-23
-
-
Pera, M.E.1
-
90
-
-
0032506231
-
Derivation of pluripotent stem cells from cultured human primordial germ stem cells
-
Shamblott M J, Axelman J, Wang S, Bugg E M, Littlefield J W, Donovan P J, Blumenthal P D, Huggins G R & Gearhart J D, Derivation of pluripotent stem cells from cultured human primordial germ stem cells, Proc Natl Acad Sci USA, 95 (1998) 13726-13731.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13726-13731
-
-
Shamblott, M.J.1
Axelman, J.2
Wang, S.3
Bugg, E.M.4
Littlefield, J.W.5
Donovan, P.J.6
Blumenthal, P.D.7
Huggins, G.R.8
Gearhart, J.D.9
-
92
-
-
84881482645
-
Great expectations
-
Thayer A N, Great expectations, Chem Eng News, 10 (1998) 19-31.
-
(1998)
Chem Eng News
, vol.10
, pp. 19-31
-
-
Thayer, A.N.1
-
93
-
-
0035135845
-
Antibodies libraries in drug and target discovery
-
Rader C, Antibodies libraries in drug and target discovery, Drug Discovery Today, 6(1) (2001) 36-43.
-
(2001)
Drug Discovery Today
, vol.6
, Issue.1
, pp. 36-43
-
-
Rader, C.1
-
94
-
-
0034241572
-
Biopharmaceutical benchmarks
-
Walsh G, Biopharmaceutical benchmarks, Natl Biotechnol, 18 (2000) 831-833.
-
(2000)
Natl Biotechnol
, vol.18
, pp. 831-833
-
-
Walsh, G.1
-
96
-
-
0034213940
-
In vitro display technologies- new tools for drug discovery
-
FitzGerald K, In vitro display technologies- new tools for drug discovery, Drug Discovery Today, 5 (2000) 253-258.
-
(2000)
Drug Discovery Today
, vol.5
, pp. 253-258
-
-
FitzGerald, K.1
-
97
-
-
0033617248
-
Targeted gene delivery to mammalian cells by filamentasis bacteriophage
-
Poul M A & Marks J D, Targeted gene delivery to mammalian cells by filamentasis bacteriophage, J Mol Biol, 288 (1999) 203-211.
-
(1999)
J Mol Biol
, vol.288
, pp. 203-211
-
-
Poul, M.A.1
Marks, J.D.2
-
98
-
-
1842746750
-
Selection of oncology targets and development of human mAbs as antitumor agents
-
(Boston, M A) August 10-15
-
Keyt B, Selection of oncology targets and development of human mAbs as Antitumor agents, IBC's Eighth Annu World Congr Agents Discovery Technology™ (Boston, M A) (August 10-15, 2003).
-
(2003)
IBC's Eighth Annu World Congr Agents Discovery Technology™
-
-
Keyt, B.1
-
101
-
-
0034603154
-
Adaptive recognition by nucleic acid aptamers
-
Hermann T & Patel D J, Adaptive recognition by nucleic acid aptamers, Science, 287 (2000) 820-825.
-
(2000)
Science
, vol.287
, pp. 820-825
-
-
Hermann, T.1
Patel, D.J.2
-
102
-
-
0005620475
-
Aptamers as therapeutic and diagnostic agents
-
Brody E N & Gold L, Aptamers as therapeutic and diagnostic agents, J Biotechnol, 74 (2000) 5-13.
-
(2000)
J Biotechnol
, vol.74
, pp. 5-13
-
-
Brody, E.N.1
Gold, L.2
-
103
-
-
0037114941
-
Aptamers as tool for target prioritization and lead identification
-
Burgstaller P, Girod A & Blind M, Aptamers as tool for target prioritization and lead identification, Drug Discovery Today, 7(24) (2002) 1221-1228.
-
(2002)
Drug Discovery Today
, vol.7
, Issue.24
, pp. 1221-1228
-
-
Burgstaller, P.1
Girod, A.2
Blind, M.3
-
104
-
-
0033642508
-
In vitro selection of RNA-aptamers
-
Marshall K A & Ellington A D, In vitro selection of RNA-aptamers, Method Enzymol, 318 (2000) 193-214.
-
(2000)
Method Enzymol
, vol.318
, pp. 193-214
-
-
Marshall, K.A.1
Ellington, A.D.2
-
105
-
-
0034852021
-
Automated selection of anti protein aptamers
-
Cox J C & Ellington A D, Automated selection of anti protein aptamers, Bioorg Med Chem, 9 (2001) 2525-2531.
-
(2001)
Bioorg Med Chem
, vol.9
, pp. 2525-2531
-
-
Cox, J.C.1
Ellington, A.D.2
-
106
-
-
0344213748
-
Chemically modified nucleic acids aptamers for in vitro solutions: Evolving evolution
-
Kusser W, Chemically modified nucleic acids aptamers for in vitro solutions: evolving evolution, J Biotechnol, 74 (2000) 27-38.
-
(2000)
J Biotechnol
, vol.74
, pp. 27-38
-
-
Kusser, W.1
-
107
-
-
0036009326
-
GnRH binding RNA and DNA spiegelmers. A novel approach toward GnRH Antagonism
-
Leva S, Lichte A, Burmeister J, Muhn P, Jahnke B, Fesser D, Erfurth J, Burgstaller P & Klussmann S, GnRH binding RNA and DNA spiegelmers. A novel approach toward GnRH Antagonism, Chem Biol, 9 (2002) 351-359.
-
(2002)
Chem Biol
, vol.9
, pp. 351-359
-
-
Leva, S.1
Lichte, A.2
Burmeister, J.3
Muhn, P.4
Jahnke, B.5
Fesser, D.6
Erfurth, J.7
Burgstaller, P.8
Klussmann, S.9
-
108
-
-
0037173068
-
In vivo properties of an anti - GnRH spiegelemrs; an example of an oligonucleotide based therapeutic substanic class
-
Wlotzka B, Leva S, Eschgfäller B, Burmese J, Kleinjung F, Kaduk C, Muhn P, Hess-Stumpp H & Klussmann S, In vivo properties of an anti - GnRH spiegelemrs; an example of an oligonucleotide based therapeutic substanic class, Proc Natl Acad Sci USA, 99 (2002) 8898-8902.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8898-8902
-
-
Wlotzka, B.1
Leva, S.2
Eschgfäller, B.3
Burmese, J.4
Kleinjung, F.5
Kaduk, C.6
Muhn, P.7
Hess-Stumpp, H.8
Klussmann, S.9
-
109
-
-
0036469778
-
Engineered allosteric ribozymes as biosensor components
-
Breaker R R, Engineered allosteric ribozymes as biosensor components, Curr Opin Biotechnol, 13 (2002) 31-39.
-
(2002)
Curr Opin Biotechnol
, vol.13
, pp. 31-39
-
-
Breaker, R.R.1
-
110
-
-
1842797241
-
RNA- aptamer as a specific modulator of Wnt signaling mediated carcinogenesis
-
(Mandalay Bay Resort and Casino Las Vegas NV) April 30- May 2
-
Jeong S & Yu J, RNA- aptamer as a specific modulator of Wnt signaling mediated carcinogenesis, Nucleic acids in drug discovery innovations in tools and target (Mandalay Bay Resort and Casino Las Vegas NV) April 30- May 2 2003.
-
(2003)
Nucleic Acids in Drug Discovery Innovations in Tools and Target
-
-
Jeong, S.1
Yu, J.2
-
111
-
-
0034687063
-
Rev- binding aptamer and CMV promoter act as decoys to inhibit HIV replication
-
Konopka K, Lee N S, Rossi J & Düzgüne N, Rev- binding aptamer and CMV promoter act as decoys to inhibit HIV replication, Gene, 255 (2000) 235-244.
-
(2000)
Gene
, vol.255
, pp. 235-244
-
-
Konopka, K.1
Lee, N.S.2
Rossi, J.3
Düzgüne, N.4
-
112
-
-
0036256028
-
Bringing picomolar protein detecrtion into proximity
-
Famulok M, Bringing picomolar protein detecrtion into proximity, Natl Biotechnol, (2002) 448-4449.
-
(2002)
Natl Biotechnol
, pp. 448-4449
-
-
Famulok, M.1
-
113
-
-
13344269000
-
From proteins to proteomics; large-scale protein identification by two dimensional electrophoresis and amino acid analysis
-
Wilkins M R, Pasquali C, Appel R D, Ou K, Golaz O, Sanchez J.-C, Yan J X, Gooley A A, Hughes G, Humphery-Smith I, Williams K L & Hochstrasser D F., From proteins to proteomics; large-scale protein identification by two dimensional electrophoresis and amino acid analysis, Biotechnol, 14 (1996) 61-65.
-
(1996)
Biotechnol
, vol.14
, pp. 61-65
-
-
Wilkins, M.R.1
Pasquali, C.2
Appel, R.D.3
Ou, K.4
Golaz, O.5
Sanchez, J.-C.6
Yan, J.X.7
Gooley, A.A.8
Hughes, G.9
Humphery-Smith, I.10
Williams, K.L.11
Hochstrasser, D.F.12
-
114
-
-
0037434980
-
From genomics to proteomics
-
Tyres M & Mann M, From genomics to proteomics, Nature, 422 (6928) (2003) 193-197.
-
(2003)
Nature
, vol.422
, Issue.6928
, pp. 193-197
-
-
Tyres, M.1
Mann, M.2
-
116
-
-
0037435030
-
Mass- spectroscopy- based proteomics
-
Aebersold R & Mann M, Mass- spectroscopy- based proteomics, Nature, 422 (6928) (2003) 198-207.
-
(2003)
Nature
, vol.422
, Issue.6928
, pp. 198-207
-
-
Aebersold, R.1
Mann, M.2
-
117
-
-
0037435022
-
Protein analysis on a proteomics scale
-
Phizicky E, Bastiaens P I H, Zhu H, Snyder M & Fields S, Protein analysis on a proteomics scale, Nature, 422 (6928) (2003) 208-215.
-
(2003)
Nature
, vol.422
, Issue.6928
, pp. 208-215
-
-
Phizicky, E.1
Bastiaens, P.I.H.2
Zhu, H.3
Snyder, M.4
Fields, S.5
-
118
-
-
0037435031
-
From words to literature in structural proteomics
-
Sali A, Glaeser R, Earnest T & Baumeister W, From words to literature in structural proteomics, Nature, 422 (6928) (2003) 216-232.
-
(2003)
Nature
, vol.422
, Issue.6928
, pp. 216-232
-
-
Sali, A.1
Glaeser, R.2
Earnest, T.3
Baumeister, W.4
-
119
-
-
0037434981
-
Disease proteomics
-
Hanash S, Disease proteomics, Nature, 422 (6928) (2003) 226-232.
-
(2003)
Nature
, vol.422
, Issue.6928
, pp. 226-232
-
-
Hanash, S.1
-
120
-
-
0037434977
-
Biomedical informatics for proteomics
-
Boguski M S and McIntosh M W, Biomedical informatics for proteomics, Nature, 422 (6928) (2003) 233-237.
-
(2003)
Nature
, vol.422
, Issue.6928
, pp. 233-237
-
-
Boguski, M.S.1
McIntosh, M.W.2
-
122
-
-
18244366113
-
An NMR- approach to structural proteomics
-
Yee A, Chang X, Pineda-Lucena A, Wu B, Semesi A, Le B, Ramelot T, Lee G M, Bhattacharyya S, Gutierrez P, Denisov A, Lee C-H, Cort J R, Kozlov G, Liao J, Finak G, Chen L, Wishart D, Lee W, McIntosh L P, Gehring K, Kennedy M A, Edwards A M & Arrowsmith C H, An NMR- approach to structural proteomics. Proc Natl Acad Sci, USA, 99 (2002) 1825-1830.
-
(2002)
Proc Natl Acad Sci. USA
, vol.99
, pp. 1825-1830
-
-
Yee, A.1
Chang, X.2
Pineda-Lucena, A.3
Wu, B.4
Semesi, A.5
Le, B.6
Ramelot, T.7
Lee, G.M.8
Bhattacharyya, S.9
Gutierrez, P.10
Denisov, A.11
Lee, C.-H.12
Cort, J.R.13
Kozlov, G.14
Liao, J.15
Finak, G.16
Chen, L.17
Wishart, D.18
Lee, W.19
McIntosh, L.P.20
Gehring, K.21
Kennedy, M.A.22
Edwards, A.M.23
Arrowsmith, C.H.24
more..
-
123
-
-
0036089703
-
Single particle imaging of macromolecules by cry-electron microscopy
-
Frank J, Single particle imaging of macromolecules by Cry-electron microscopy, Annu Rev Biophy Biomol Struct, 31 (2002) 303-319.
-
(2002)
Annu Rev Biophy Biomol Struct
, vol.31
, pp. 303-319
-
-
Frank, J.1
-
124
-
-
0037050004
-
Systematic identification of protein complexes in saccharomyces cerevisiac by mass spectroscopy
-
Ho Y, Gruhler A, Heilbut A, Bader G D, Moore L, Adams S-L, Millar A, Taylor P, Bennett K, Boutilier K, Yang L et al., Systematic identification of protein complexes in saccharomyces cerevisiac by mass spectroscopy, Nature, 415 (2002) 180-183.
-
(2002)
Nature
, vol.415
, pp. 180-183
-
-
Ho, Y.1
Gruhler, A.2
Heilbut, A.3
Bader, G.D.4
Moore, L.5
Adams, S.-L.6
Millar, A.7
Taylor, P.8
Bennett, K.9
Boutilier, K.10
Yang, L.11
-
126
-
-
0037133275
-
Mapping by site directed mutagenesis of the region responsible for Cohesin-dockerin interaction on the surface of the seventh Cohesin domain of Clostridium thermocellum CipA
-
Miras I. Schaeffer F, Beguin P & Alzari P M, Mapping by site directed mutagenesis of the region responsible for Cohesin-dockerin interaction on the surface of the seventh Cohesin domain of Clostridium thermocellum CipA, Biochemistry, 41 (2002) 2115-2119.
-
(2002)
Biochemistry
, vol.41
, pp. 2115-2119
-
-
Miras, I.1
Schaeffer, F.2
Beguin, P.3
Alzari, P.M.4
-
127
-
-
0012522653
-
Protein chips from concept of practice
-
Lee Y-S & Mrksich M, Protein chips from concept of practice, Trends in Biotechnol (Suppl.) 20 (12) (2002) S 14-S 18.
-
(2002)
Trends in Biotechnol
, vol.20
, Issue.12 SUPPL.
-
-
Lee, Y.-S.1
Mrksich, M.2
-
128
-
-
0012574002
-
Affinity- capture reagents for protein arrays
-
Elia G, Silacci M, Scheurer S, Scheuermann J, & Neri D, Affinity- capture reagents for protein arrays, Trends in Biotechnol (Suppl.), 20 (12) (2002) S 19-S 22.
-
(2002)
Trends in Biotechnol
, vol.20
, Issue.12 SUPPL.
-
-
Elia, G.1
Silacci, M.2
Scheurer, S.3
Scheuermann, J.4
Neri, D.5
-
129
-
-
0009623305
-
Fluorescence resonance energy transfer: A diagnostic tool in oligonucleotide therapy
-
Singh Y, Pandey A, Dubey K K, Watal G & Misra K, Fluorescence Resonance Energy Transfer: A Diagnostic tool in oligonucleotide therapy, Curr Sci, 78(4) (2000) 487-492.
-
(2000)
Curr Sci
, vol.78
, Issue.4
, pp. 487-492
-
-
Singh, Y.1
Pandey, A.2
Dubey, K.K.3
Watal, G.4
Misra, K.5
-
130
-
-
1842746748
-
Design development and Synthesis of a novel labeled PNA monomer incorporated in DNA- Hexamer to act as a hybridization probe by FRET
-
Communicated
-
Shukla V, Mishra S, Watal G & Misra K, Design development and Synthesis of a novel labeled PNA monomer incorporated in DNA- hexamer to act as a hybridization probe by FRET, Org & Biomol Chem. (2003) (Communicated).
-
(2003)
Org and Biomol Chem.
-
-
Shukla, V.1
Mishra, S.2
Watal, G.3
Misra, K.4
-
131
-
-
0037116832
-
Proteomic analysis at the bedside; early detection of cancer
-
Petricoin E F, Ardekani A M, Hitt B A, Levine P J, Fusaro V A, Steinberg S M, Mills G B, Simone C & Fishman D A et al., Proteomic analysis at the bedside; early detection of cancer, Lancet, 359 (2002) 572-577.
-
(2002)
Lancet
, vol.359
, pp. 572-577
-
-
Petricoin, E.F.1
Ardekani, A.M.2
Hitt, B.A.3
Levine, P.J.4
Fusaro, V.A.5
Steinberg, S.M.6
Mills, G.B.7
Simone, C.8
Fishman, D.A.9
-
132
-
-
0036210918
-
Proteomics analysis and identification of new biomarkers and therapeutic targets for invasive ovarian
-
Jones M B, Krutzsch H, Shu H, Zhao Y, Liotta L A, Kohn E C & Petricoin E F, Proteomics analysis and identification of new biomarkers and therapeutic targets for invasive ovarian, Proteomics, 2 (2002) 76-84.
-
(2002)
Proteomics
, vol.2
, pp. 76-84
-
-
Jones, M.B.1
Krutzsch, H.2
Shu, H.3
Zhao, Y.4
Liotta, L.A.5
Kohn, E.C.6
Petricoin, E.F.7
-
133
-
-
0036645099
-
Serum protein fingerprinting coupled with a pattern matching algorithm distinguishes prostate cancer from begin prostate hyperplasic and healthy men
-
Adam B L, Qu Y, Davis J W, Ward M D, Clements M A, Cazares L H, Semmes O J, Schellhammer P F, Yasui Y, Feng Z & Jr. G L Wright., Serum protein fingerprinting coupled with a pattern matching algorithm distinguishes prostate cancer from begin prostate hyperplasic & Healthy, men, Cancer Res, 62 (2002) 3609-3614.
-
(2002)
Cancer Res
, vol.62
, pp. 3609-3614
-
-
Adam, B.L.1
Qu, Y.2
Davis, J.W.3
Ward, M.D.4
Clements, M.A.5
Cazares, L.H.6
Semmes, O.J.7
Schellhammer, P.F.8
Yasui, Y.9
Feng Jr., Z.10
Wright, G.L.11
-
134
-
-
18444387979
-
Purification and characterization of the mammaglobin lipophilin B complex, a promising diagnostic marker for breast cancer
-
Carter D, Douglass J F, Cornellison C D, Retter M W, Johnson J C, Bennington A A, Fleming T P, Reed S G, Houghton R L, Diamond D L & Vedvick T S, Purification and characterization of the mammaglobin lipophilin B complex, a promising diagnostic marker for breast cancer, Biochemistry, 28 (2002) 6714-6722.
-
(2002)
Biochemistry
, vol.28
, pp. 6714-6722
-
-
Carter, D.1
Douglass, J.F.2
Cornellison, C.D.3
Retter, M.W.4
Johnson, J.C.5
Bennington, A.A.6
Fleming, T.P.7
Reed, S.G.8
Houghton, R.L.9
Diamond, D.L.10
Vedvick, T.S.11
-
135
-
-
0036324715
-
Proteomics and bioinformatics approaches for identification of serum biomarkers to detect breast cancer
-
Li J, Zhang Z, Rosenzweig J, Wang Y Y & Chan D W Proteomics and bioinformatics approaches for identification of serum biomarkers to detect breast cancer, Clin Chem, 48 (2002) 1296-1304.
-
(2002)
Clin Chem
, vol.48
, pp. 1296-1304
-
-
Li, J.1
Zhang, Z.2
Rosenzweig, J.3
Wang, Y.Y.4
Chan, D.W.5
-
136
-
-
0036525708
-
Toxicoproteomics - A new preclinical
-
Bandara L R & Kennedy S, Toxicoproteomics - a new preclinical, Drug Discovery Today, 7(7) (2002) 411-418.
-
(2002)
Drug Discovery Today
, vol.7
, Issue.7
, pp. 411-418
-
-
Bandara, L.R.1
Kennedy, S.2
-
137
-
-
0033920278
-
Two dimensional data base of mouse liver proteins changes in hepatic protein levels following treatment with acetaminophen or its nontoxic egioisomer 3-occatamidophenol
-
Fountoulakis M, Berndt P, Boclsterli U A, Crameri F, Winter M, Albertini S, Jones M B, Krutzsch H, Shu H, Zhao Y, Liotta L A, Kohn E C, Two dimensional data base of mouse liver proteins changes in hepatic protein levels following treatment with acetaminophen or its nontoxic egioisomer 3-occatamidophenol, Electrophesis, 21 (2000) 2148-2161.
-
(2000)
Electrophesis
, vol.21
, pp. 2148-2161
-
-
Fountoulakis, M.1
Berndt, P.2
Boclsterli, U.A.3
Crameri, F.4
Winter, M.5
Albertini, S.6
Jones, M.B.7
Krutzsch, H.8
Shu, H.9
Zhao, Y.10
Liotta, L.A.11
Kohn, E.C.12
-
138
-
-
0008708652
-
Regional protein alternations in rat kidneys induced by lead exposure
-
Witzmann F A, Fultz C D, Grant R A, Wright L S, Kornguth S E & Siegel F L, Regional protein alternations in rat kidneys induced by lead exposure, Electrophoresis, 21 (1999) 976-984.
-
(1999)
Electrophoresis
, vol.21
, pp. 976-984
-
-
Witzmann, F.A.1
Fultz, C.D.2
Grant, R.A.3
Wright, L.S.4
Kornguth, S.E.5
Siegel, F.L.6
-
139
-
-
0035957603
-
Cardiovascular proteomics; evolution and potential
-
Arrell D K, Neverova I & Eyk J E V, Cardiovascular proteomics; evolution and potential, Circ Res, 88 (2001) 763-773.
-
(2001)
Circ Res
, vol.88
, pp. 763-773
-
-
Arrell, D.K.1
Neverova, I.2
Eyk, J.E.V.3
-
140
-
-
0035503380
-
Proteomic based identification of protein gene product 9.5 as a tumor antigen that induces a humoral immune response in lung
-
Brichory F, Beer D, LeNaour F, Giordano T & Hanash S, Proteomic based identification of protein gene product 9.5 as a tumor antigen that induces a humoral immune response in lung, Cancer Res, 61 (2001) 7908-7912.
-
(2001)
Cancer Res
, vol.61
, pp. 7908-7912
-
-
Brichory, F.1
Beer, D.2
LeNaour, F.3
Giordano, T.4
Hanash, S.5
-
141
-
-
0036499607
-
Is telomerase the cure all and end all?
-
Halt S E, Is telomerase the cure all and end all?, Drug Discovery Today, 7(5) (2002) 88.
-
(2002)
Drug Discovery Today
, vol.7
, Issue.5
, pp. 88
-
-
Halt, S.E.1
-
142
-
-
0041317162
-
Synthesis of a novel anticancer prodrug designed to target telomerase sequence
-
Mishra S, Tripathi S & Misra K, Synthesis of a novel anticancer prodrug designed to target telomerase sequence, Nucl Acids Res (suppl), No. 2 (2002) 277-278.
-
(2002)
Nucl Acids Res
, Issue.2 SUPPL.
, pp. 277-278
-
-
Mishra, S.1
Tripathi, S.2
Misra, K.3
-
143
-
-
0037203972
-
Antitumor polycyclic acridies Synthetic and telomerase inhibitory activity of methylated pentacyclic acridinium salts
-
Heald R A, Modi C, Cookson J C, Hutchinson I, Laughton C A, Gowan S M, Kelland L R & Stevens M F G, Antitumor polycyclic acridies Synthetic and telomerase inhibitory activity of methylated pentacyclic acridinium salts, J Med Chem, 45 (2002) 590-597.
-
(2002)
J Med Chem
, vol.45
, pp. 590-597
-
-
Heald, R.A.1
Modi, C.2
Cookson, J.C.3
Hutchinson, I.4
Laughton, C.A.5
Gowan, S.M.6
Kelland, L.R.7
Stevens, M.F.G.8
-
144
-
-
0035398526
-
A genomic perspective on human proteases as drug targets
-
Southan C, A genomic perspective on human proteases as drug targets, Drug Discovery Today, 6(13) (2001) 681-688.
-
(2001)
Drug Discovery Today
, vol.6
, Issue.13
, pp. 681-688
-
-
Southan, C.1
-
145
-
-
0036228770
-
Attenuation of leptin signal transduction obesity by protein tyrosine phosphatase 1β
-
Cheng A, Uetani N, Simoncic P D, Chaubey V P, Lee-Loy A, McGlade C J, Kennedy B P, & Tremblay M L, Attenuation of leptin signal transduction obesity by protein tyrosine phosphatase 1β, Dev Cell, 2 (2002) 497-503.
-
(2002)
Dev Cell
, vol.2
, pp. 497-503
-
-
Cheng, A.1
Uetani, N.2
Simoncic, P.D.3
Chaubey, V.P.4
Lee-Loy, A.5
McGlade, C.J.6
Kennedy, B.P.7
Tremblay, M.L.8
-
146
-
-
0036807325
-
Selecting protein tyrosine phosphate as drug targets
-
Huijsduijnen R H, Bombrun A & Swinnen D, Selecting protein tyrosine phosphate as drug targets, Drug Discovery Today, 7(9) (2002) 1013-1019.
-
(2002)
Drug Discovery Today
, vol.7
, Issue.9
, pp. 1013-1019
-
-
Huijsduijnen, R.H.1
Bombrun, A.2
Swinnen, D.3
-
147
-
-
0035137043
-
Carbohydrate sulfotransferases: Novel therapeutic targets for inflammation, viral infection and cancer
-
Hemmerich S, Carbohydrate sulfotransferases: novel therapeutic targets for inflammation, viral infection and cancer, Drug Discovery Today, 6(1) (2001) 27-35.
-
(2001)
Drug Discovery Today
, vol.6
, Issue.1
, pp. 27-35
-
-
Hemmerich, S.1
|