An antisense oligonucleotide primer

Antisense and Nucleic Acid Drug Development

Volumn 9, Issue 4, 1999, Pages 351-357

  Hogrefe, Richard I ^a  

^a TriLink BioTechnologies Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE;

BIOTECHNOLOGY; COST; GENE EXPRESSION REGULATION; GENE THERAPY; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVIEW;

EID: 0032817254     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1999.9.351     Document Type: Review

References (8)

1. AGRAWAL, S., and GOODCHILD, J. (1987). Oligonucleoside methylphosphonates: Synthesis and enzymic degradation. Tetrahedron Lett. 28, 3539-3542.
2. AGRAWAL, K.L., and RIFTINA, F. (1979). Synthesis and enzymatic properties of deoxyribooligonucleotides containing methyl and phenylphosphonate linkages. Nucleic Acids Res. 6, 3009-3023.
3. AGRAWAL, S., TEMSAMANI, J., and TANG, J.Y. (1991). Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice. Proc. Natl. Acad. Sci. USA 88, 7595-7599.
4. AGRAWAL, S., ZHANG, X., LU, Z., ZHAO, H., TAMBURIN, J.M., VAN, J., CAI, H., DIASIO, R.B., HABUS, I, JIANG, Z., IYER, R.P., YU, D., and ZHANG, R. (1995). Absorption, tissue distribution and in vivo stability in rats of a hybrid antisense oligonucleotide following oral administration. Biochem. Pharmacol. 50, 571-576.
5. BLAKE, K., MURAKAMI, A., SPITZ, S.A., GLAVE, S.A., REDDY, M.P., TS'O, P.O.P., and MILLER, P.S. (1985). Hybridization arrest of globin synthesis in rabbit reticulocyte lysates and cells by oligodeoxyribonucleoside methylphosphonates. Biochemistry 24, 6139-6145.
6. BOGGS, R.T., McGRAW, K., CONDON, T., FLOURNOY, S., VILLIET, P., BENNETT, C.F., and MONIA, B.P. (1997). Characterization and modulation of immune stimulation by modified oligonucleotides. Antisense Nucleic Acid Drug Dev. 7, 461-471.
7. WOOLF, T.M., MELTON, D.A., and JENNINGS, C.G.B. (1992). Specificity of antisense oligonucleotides in vivo. Proc. Natl. Acad. Sci. USA 89, 7305-7309.
8. ZHOU, W., and AGRAWAL, S. (1998). Mixed-backbone oligonucleotides as second-generation antisense agents with reduced phosphorothioate-related side effects. Bioorg. Med. Chem. Lett. 8, 3269-3274.