-
1
-
-
0036187036
-
Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation
-
Acehan, D., Jiang, X., Morgan, D.G., Heuser, J.E., Wang, X., and Akey, C.W. (2002). Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. Mol. Cell 9, 423-432.
-
(2002)
Mol. Cell
, vol.9
, pp. 423-432
-
-
Acehan, D.1
Jiang, X.2
Morgan, D.G.3
Heuser, J.E.4
Wang, X.5
Akey, C.W.6
-
2
-
-
0038726089
-
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK
-
Allan, L.A., Morrice, N., Brady, S., Magee, G., Pathak, S., and Clarke, P.R. (2003). Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK. Nat. Cell Biol. 5, 647-654.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 647-654
-
-
Allan, L.A.1
Morrice, N.2
Brady, S.3
Magee, G.4
Pathak, S.5
Clarke, P.R.6
-
3
-
-
0030746636
-
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
-
Ambrosini, G., Adida, C., and Altieri, D.C. (1997). A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat. Med. 3, 917-921.
-
(1997)
Nat. Med.
, vol.3
, pp. 917-921
-
-
Ambrosini, G.1
Adida, C.2
Altieri, D.C.3
-
4
-
-
0034708504
-
Expression and functional analysis of Apaf-1 isoforms. Extra WD-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9
-
Benedict, M.A., Hu, Y.M., Inohara, N., and Núñez, G. (2000). Expression and functional analysis of Apaf-1 isoforms. Extra WD-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9. J. Biol. Chem. 275, 8461-8468.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8461-8468
-
-
Benedict, M.A.1
Hu, Y.M.2
Inohara, N.3
Núñez, G.4
-
5
-
-
0037291871
-
A unified model for apical caspase activation
-
Boatright, K.M., Renatus, M., Scott, F.L., Sperandio, S., Shin, H., Pedersen, I.M., Ricci, J.E., Edris, W.A., Sutherlin, D.P., Green, D.R., and Salvesen, G.S. (2003). A unified model for apical caspase activation. Mol. Cell 11, 529-541.
-
(2003)
Mol. Cell
, vol.11
, pp. 529-541
-
-
Boatright, K.M.1
Renatus, M.2
Scott, F.L.3
Sperandio, S.4
Shin, H.5
Pedersen, I.M.6
Ricci, J.E.7
Edris, W.A.8
Sutherlin, D.P.9
Green, D.R.10
Salvesen, G.S.11
-
6
-
-
0035872199
-
Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation
-
Brognard, J., Clark, A.S., Ni, Y., and Dennis, P.A. (2001). Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation. Cancer Res. 61, 3986-3997.
-
(2001)
Cancer Res.
, vol.61
, pp. 3986-3997
-
-
Brognard, J.1
Clark, A.S.2
Ni, Y.3
Dennis, P.A.4
-
7
-
-
0033499729
-
Cytosolic delivery of granzyme B by bacterial toxins: Evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin
-
Browne, K.A., Blink, E., Sutton, V.R., Froelich, C.J., Jans, D.A., and Trapani, J.A. (1999). Cytosolic delivery of granzyme B by bacterial toxins: Evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin. Mol. Cell. Biol. 19, 8604-8615.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 8604-8615
-
-
Browne, K.A.1
Blink, E.2
Sutton, V.R.3
Froelich, C.J.4
Jans, D.A.5
Trapani, J.A.6
-
8
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone, M.H., Roy, N., Stennicke, H.R., Salvesen, G.S., Franke, T.F., Stanbridge, E., Frisch, S., and Reed, J.C. (1998). Regulation of cell death protease caspase-9 by phosphorylation. Science 282, 1318-1321.
-
(1998)
Science
, vol.282
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
Salvesen, G.S.4
Franke, T.F.5
Stanbridge, E.6
Frisch, S.7
Reed, J.C.8
-
9
-
-
0036035259
-
Involvement of redox events in caspase activation in zinc-depleted airway epithelial cells
-
Carter, J., Truong-Tran, A., Grosser, D., Ho, L., Ruffin, R., and Zalewski, P. (2002). Involvement of redox events in caspase activation in zinc-depleted airway epithelial cells. Biochem. Biophys. Res. Commun. 297, 1062-1070.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.297
, pp. 1062-1070
-
-
Carter, J.1
Truong-Tran, A.2
Grosser, D.3
Ho, L.4
Ruffin, R.5
Zalewski, P.6
-
10
-
-
0037066727
-
De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1
-
Chalfant, C.E., Rathman, K., Pinkerman, R.L., Wood, R.E., Obeid, L.M., Ogretmen, B., and Hannun, Y.A. (2002). De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1. J. Biol. Chem. 277, 12587-12595.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12587-12595
-
-
Chalfant, C.E.1
Rathman, K.2
Pinkerman, R.L.3
Wood, R.E.4
Obeid, L.M.5
Ogretmen, B.6
Hannun, Y.A.7
-
11
-
-
0037930793
-
Oligomerization is a general mechanism for the activation of apoptosis initiator and inflammatory procaspases
-
Chang, D.W., Ditsworth, D., Liu, H., Srinivasula, S.M., Alnemri, E.S., and Yang, X. (2003). Oligomerization is a general mechanism for the activation of apoptosis initiator and inflammatory procaspases. J. Biol. Chem. 278, 16466-16469.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16466-16469
-
-
Chang, D.W.1
Ditsworth, D.2
Liu, H.3
Srinivasula, S.M.4
Alnemri, E.S.5
Yang, X.6
-
12
-
-
0037069938
-
Down-regulation of caspase 3 in breast cancer: A possible mechanism for chemoresistance
-
Devarajan, E., Sahin, A.A., Chen, J.S., Krishnamurthy, R.R., Aggarwal, N., Brun, A.M., Sapino, A., Zhang, F., Sharma, D., Yang, X.H. et al. (2002). Down-regulation of caspase 3 in breast cancer: A possible mechanism for chemoresistance. Oncogene 21, 8843-8851.
-
(2002)
Oncogene
, vol.21
, pp. 8843-8851
-
-
Devarajan, E.1
Sahin, A.A.2
Chen, J.S.3
Krishnamurthy, R.R.4
Aggarwal, N.5
Brun, A.M.6
Sapino, A.7
Zhang, F.8
Sharma, D.9
Yang, X.H.10
-
13
-
-
0344053451
-
In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
-
Fernandes-Alnemri, T., Armstrong, R.C., Krebs, J., Srinivasula, S.M., Wang, L., Bullrich, F., Fritz, L.C., Trapani, J.A., Tomaselli, K.J., Litwack, G. et al. (1996). In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc. Natl. Acad. Sci. USA 93, 7464-7469.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7464-7469
-
-
Fernandes-Alnemri, T.1
Armstrong, R.C.2
Krebs, J.3
Srinivasula, S.M.4
Wang, L.5
Bullrich, F.6
Fritz, L.C.7
Trapani, J.A.8
Tomaselli, K.J.9
Litwack, G.10
-
14
-
-
0242432345
-
Many cuts to ruin: A comprehensive update of caspase substrates
-
Fischer, U., Jänicke, R.U., and Schulze-Osthoff, K. (2003). Many cuts to ruin: A comprehensive update of caspase substrates. Cell Death Differ. 10, 76-100.
-
(2003)
Cell Death Differ.
, vol.10
, pp. 76-100
-
-
Fischer, U.1
Jänicke, R.U.2
Schulze-Osthoff, K.3
-
15
-
-
0035901938
-
Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance
-
Friedrich, K., Wieder, T., von Haefen, C., Radetzki, S., Jänicke, R., Schulze-Osthoff, K., Dorken, B., and Daniel, P.T. (2001). Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance. Oncogene 20, 2749-2760.
-
(2001)
Oncogene
, vol.20
, pp. 2749-2760
-
-
Friedrich, K.1
Wieder, T.2
von Haefen, C.3
Radetzki, S.4
Jänicke, R.5
Schulze-Osthoff, K.6
Dorken, B.7
Daniel, P.T.8
-
16
-
-
0033890808
-
Reduced expression of ICE/caspase1 and CPP32/caspase3 in human hepatocellular carcinoma
-
Fujikawa, K., Shiraki, K., Sugimoto, K., Ito, T., Yamanaka, T., Takase, K., and Nakano, T. (2000). Reduced expression of ICE/caspase1 and CPP32/caspase3 in human hepatocellular carcinoma. Anticancer Res. 20, 1927-1932.
-
(2000)
Anticancer Res.
, vol.20
, pp. 1927-1932
-
-
Fujikawa, K.1
Shiraki, K.2
Sugimoto, K.3
Ito, T.4
Yamanaka, T.5
Takase, K.6
Nakano, T.7
-
17
-
-
0033136316
-
Apoptosis induced by granzyme B-glycosaminoglycan complexes: Implications for granule-mediated apoptosis in vivo
-
Galvin, J.P., Spaeny-Dekking, L.H.A., Wang, B., Seth, P., Hack, C.E., and Froelich, C.J. (1999). Apoptosis induced by granzyme B-glycosaminoglycan complexes: Implications for granule-mediated apoptosis in vivo. J. Immunol. 162, 5345-5350.
-
(1999)
J. Immunol.
, vol.162
, pp. 5345-5350
-
-
Galvin, J.P.1
Spaeny-Dekking, L.H.A.2
Wang, B.3
Seth, P.4
Hack, C.E.5
Froelich, C.J.6
-
18
-
-
0036463405
-
A matter of life and death
-
Green, D.R., and Evan, G.I. (2002). A matter of life and death. Cancer Cell 1, 19-30.
-
(2002)
Cancer Cell
, vol.1
, pp. 19-30
-
-
Green, D.R.1
Evan, G.I.2
-
19
-
-
0036729435
-
Glucocorticoids inhibit lung cancer cell growth through both the extracellular signal-related kinase pathway and cell cycle regulators
-
Greenberg, A.K., Hu, J., Basu, S., Hay, J., Reibman, J., Yie, T.A., Tchou-Wong, K.M., Rom, W.N., and Lee, T.C. (2002). Glucocorticoids inhibit lung cancer cell growth through both the extracellular signal-related kinase pathway and cell cycle regulators. Am. J. Respir. Cell Mol. Biol. 27, 320-328.
-
(2002)
Am. J. Respir. Cell Mol. Biol.
, vol.27
, pp. 320-328
-
-
Greenberg, A.K.1
Hu, J.2
Basu, S.3
Hay, J.4
Reibman, J.5
Yie, T.A.6
Tchou-Wong, K.M.7
Rom, W.N.8
Lee, T.C.9
-
20
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D., and Weinberg, R.A. (2000). The hallmarks of cancer. Cell 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
21
-
-
0020637308
-
India ink staining of proteins on nitrocellulose paper
-
Hancock, K., and Tsang, V.C.W. (1983). India ink staining of proteins on nitrocellulose paper. Anal. Biochem. 133, 157-162.
-
(1983)
Anal. Biochem.
, vol.133
, pp. 157-162
-
-
Hancock, K.1
Tsang, V.C.W.2
-
22
-
-
0032423527
-
Immunohistochemistry of caspase3/CPP32 in human stomach and its correlation with cell proliferation and apoptosis
-
Hoshi, T., Sasano, H., Kato, K., Yabuki, N., Ohara, S., Konno, R., Asaki, S., Toyota, T., Tateno, H., and Nagura, H. (1998). Immunohistochemistry of caspase3/CPP32 in human stomach and its correlation with cell proliferation and apoptosis. Anticancer Res. 18, 4347-4353.
-
(1998)
Anticancer Res.
, vol.18
, pp. 4347-4353
-
-
Hoshi, T.1
Sasano, H.2
Kato, K.3
Yabuki, N.4
Ohara, S.5
Konno, R.6
Asaki, S.7
Toyota, T.8
Tateno, H.9
Nagura, H.10
-
23
-
-
0040298568
-
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
-
Jänicke, R.U., Sprengart, M.L., Wati, M.R., and Porter, A.G. (1998). Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J. Biol. Chem. 273, 9357-9360.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9357-9360
-
-
Jänicke, R.U.1
Sprengart, M.L.2
Wati, M.R.3
Porter, A.G.4
-
24
-
-
0034613302
-
Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1
-
Jiang, X., and Wang, X. (2000). Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1. J. Biol. Chem. 275, 31199-31203.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31199-31203
-
-
Jiang, X.1
Wang, X.2
-
25
-
-
0037097012
-
The structure of procaspase 6 is similar to that of active mature caspase 6
-
Kang, B. H., Ko, E., Kwon, O. K., and Choi, K.Y. (2002). The structure of procaspase 6 is similar to that of active mature caspase 6. Biochem. J. 364, 629-634.
-
(2002)
Biochem. J.
, vol.364
, pp. 629-634
-
-
Kang, B.H.1
Ko, E.2
Kwon, O.K.3
Choi, K.Y.4
-
26
-
-
0036049348
-
Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells
-
Kim, K.B., Lotan, R., Yue, P., Sporn, M.B., Suh, N., Gribble, G.W., Honda, T., Wu, G.S., Hong, W.K., and Sun, S.Y. (2002). Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells. Mol. Cancer Ther. 1, 177-184.
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 177-184
-
-
Kim, K.B.1
Lotan, R.2
Yue, P.3
Sporn, M.B.4
Suh, N.5
Gribble, G.W.6
Honda, T.7
Wu, G.S.8
Hong, W.K.9
Sun, S.Y.10
-
27
-
-
0035824635
-
Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8
-
Kischkel, F.C., Lawrence, D.A., Tinel, A., LeBlanc, H., Virmani, A., Schow, P., Gazdar, A., Blenis, J., Arnott, D., and Ashkenazi, A. (2001). Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8. J. Biol. Chem. 276, 46639-46646.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46639-46646
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Tinel, A.3
LeBlanc, H.4
Virmani, A.5
Schow, P.6
Gazdar, A.7
Blenis, J.8
Arnott, D.9
Ashkenazi, A.10
-
28
-
-
0033564103
-
Dead or dying: Necrosis versus apoptosis in caspase-deficient human renal cell carcinoma
-
Kolenko, V., Uzzo, R.G., Bukowski, R., Bander, N.H., Novick, A.C., Hsi, E.D., and Finke, J.H. (1999). Dead or dying: Necrosis versus apoptosis in caspase-deficient human renal cell carcinoma. Cancer Res. 59, 2838-2842.
-
(1999)
Cancer Res.
, vol.59
, pp. 2838-2842
-
-
Kolenko, V.1
Uzzo, R.G.2
Bukowski, R.3
Bander, N.H.4
Novick, A.C.5
Hsi, E.D.6
Finke, J.H.7
-
29
-
-
0030960657
-
Immunohistochemical analysis of in vivo patterns of expression of CPP32 (caspase-3), a cell death protease
-
Krajewska, M., Wang, H.G., Krajewski, S., Zapata, J.M., Shabaik, A., Gascoyne, R., and Reed, J.C. (1997). Immunohistochemical analysis of in vivo patterns of expression of CPP32 (caspase-3), a cell death protease. Cancer Res. 57, 1605-1613.
-
(1997)
Cancer Res.
, vol.57
, pp. 1605-1613
-
-
Krajewska, M.1
Wang, H.G.2
Krajewski, S.3
Zapata, J.M.4
Shabaik, A.5
Gascoyne, R.6
Reed, J.C.7
-
30
-
-
0035206434
-
Cysteine proteinases in tumor cell growth and apoptosis
-
Křepela, E. (2001). Cysteine proteinases in tumor cell growth and apoptosis. Neoplasma 48, 332-349.
-
(2001)
Neoplasma
, vol.48
, pp. 332-349
-
-
Křepela, E.1
-
31
-
-
0036905316
-
Mitochondria-mediated apoptosis of lung epithelial cells in idiopathic interstitial pneumonias
-
Kuwano, K., Hagimoto, N., Maeyama, T., Fujita, M., Yoshimi, M., Inoshima, I., Nakashima, N., Hamada, N., Watanabe, K., and Hara, N. (2002). Mitochondria-mediated apoptosis of lung epithelial cells in idiopathic interstitial pneumonias. Lab. Invest. 82, 1695-1706.
-
(2002)
Lab. Invest.
, vol.82
, pp. 1695-1706
-
-
Kuwano, K.1
Hagimoto, N.2
Maeyama, T.3
Fujita, M.4
Yoshimi, M.5
Inoshima, I.6
Nakashima, N.7
Hamada, N.8
Watanabe, K.9
Hara, N.10
-
32
-
-
0036695853
-
Non-small cell lung cancers frequently express phosphorylated Akt; an immunohistochemical study
-
Lee, S.H., Kim, H.S., Park, W.S., Kim, S.Y., Lee, K.Y., Kim, S.H., Lee, J.Y., and Yoo, N.J. (2002). Non-small cell lung cancers frequently express phosphorylated Akt; an immunohistochemical study. APMIS 110, 587-592.
-
(2002)
APMIS
, vol.110
, pp. 587-592
-
-
Lee, S.H.1
Kim, H.S.2
Park, W.S.3
Kim, S.Y.4
Lee, K.Y.5
Kim, S.H.6
Lee, J.Y.7
Yoo, N.J.8
-
33
-
-
0032555215
-
The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis
-
Liu, X., Li, P., Widlak, P., Zou, H., Luo, X., Garrard, W.T., and Wang, X. (1998). The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis. Proc. Natl. Acad. Sci. USA 95, 8461-8466.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8461-8466
-
-
Liu, X.1
Li, P.2
Widlak, P.3
Zou, H.4
Luo, X.5
Garrard, W.T.6
Wang, X.7
-
35
-
-
0038182537
-
HBXIP functions as a cofactor of survivin in apoptosis suppression
-
Marusawa, H., Matsuzawa, S., Welsh, K., Zou, H., Armstrong, R., Tamm, I., and Reed, J.C. (2003). HBXIP functions as a cofactor of survivin in apoptosis suppression. EMBO J. 22, 2729-2740.
-
(2003)
EMBO J.
, vol.22
, pp. 2729-2740
-
-
Marusawa, H.1
Matsuzawa, S.2
Welsh, K.3
Zou, H.4
Armstrong, R.5
Tamm, I.6
Reed, J.C.7
-
36
-
-
0038505594
-
Expression of epidermal growth factor receptor (EGFR) and downstream-activated peptides in surgically excised non-small-cell lung cancer (NSCLC)
-
Mukohara, T., Kudoh, S., Yamauchi, S., Kimura, T., Yoshimura, N., Kanazawa, H., Hirata, K., Wanibuchi, H., Fukushima, S., Inoue, K. et al. (2003). Expression of epidermal growth factor receptor (EGFR) and downstream-activated peptides in surgically excised non-small-cell lung cancer (NSCLC). Lung Cancer 41, 123-130.
-
(2003)
Lung Cancer
, vol.41
, pp. 123-130
-
-
Mukohara, T.1
Kudoh, S.2
Yamauchi, S.3
Kimura, T.4
Yoshimura, N.5
Kanazawa, H.6
Hirata, K.7
Wanibuchi, H.8
Fukushima, S.9
Inoue, K.10
-
37
-
-
0032785021
-
Caspase structure, proteolytic substrates, and function during apoptotic cell death
-
Nicholson, D.W. (1999). Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ. 6, 1028-1042.
-
(1999)
Cell Death Differ.
, vol.6
, pp. 1028-1042
-
-
Nicholson, D.W.1
-
38
-
-
0037532397
-
APAF-1 -ALT, a novel alternative splicing form of APAF-1, potentially causes impeded ability of undergoing DNA damage-induced apoptosis in the LNCaP human prostate cancer cell line
-
Ogawa, T., Shiga, K., Hashimoto, S., Kobayashi, T., Horii, A., and Furukawa, T. (2003). APAF-1 -ALT, a novel alternative splicing form of APAF-1, potentially causes impeded ability of undergoing DNA damage-induced apoptosis in the LNCaP human prostate cancer cell line. Biochem. Biophys. Res. Commun. 306, 537-543.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.306
, pp. 537-543
-
-
Ogawa, T.1
Shiga, K.2
Hashimoto, S.3
Kobayashi, T.4
Horii, A.5
Furukawa, T.6
-
39
-
-
0034990676
-
Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma
-
Palmerini, F., Devilard, E., Jarry, A., Birg, F., and Xerri, L. (2001). Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma. Hum. Pathol. 32, 461-467.
-
(2001)
Hum. Pathol.
, vol.32
, pp. 461-467
-
-
Palmerini, F.1
Devilard, E.2
Jarry, A.3
Birg, F.4
Xerri, L.5
-
40
-
-
0033573020
-
Caspase-9 and Apaf-1 form an active holoenzyme
-
Rodriguez, J., and Lazebnik, Y. (1999). Caspase-9 and Apaf-1 form an active holoenzyme. Gene Dev. 13, 3179-3184.
-
(1999)
Gene Dev.
, vol.13
, pp. 3179-3184
-
-
Rodriguez, J.1
Lazebnik, Y.2
-
41
-
-
14344272939
-
Maintenance of caspase-3 proenzyme dormancy by an intrinsic safety catch regulatory tripeptide
-
Roy, S., Bayly, C.I., Gareau, Y., Houtzager, V.M., Kargman, S., Keen, S.L., Rowland, K., Seiden, I.M., Thomberry, N.A., and Nicholson, D.W. (2001). Maintenance of caspase-3 proenzyme dormancy by an intrinsic safety catch regulatory tripeptide. Proc. Natl. Acad. Sci. USA 98, 6132-6137.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 6132-6137
-
-
Roy, S.1
Bayly, C.I.2
Gareau, Y.3
Houtzager, V.M.4
Kargman, S.5
Keen, S.L.6
Rowland, K.7
Seiden, I.M.8
Thomberry, N.A.9
Nicholson, D.W.10
-
42
-
-
0033539067
-
Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation
-
Sahara, S., Aoto, M., Eguchi, Y., Imamoto, N., Yoneda, Y., and Tsujimoto, Y. (1999). Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation. Nature 401, 168-173.
-
(1999)
Nature
, vol.401
, pp. 168-173
-
-
Sahara, S.1
Aoto, M.2
Eguchi, Y.3
Imamoto, N.4
Yoneda, Y.5
Tsujimoto, Y.6
-
43
-
-
0036088471
-
IAP proteins: Blocking the road to death's door
-
Salvesen, G.S., and Duckett, C.S. (2002). IAP proteins: blocking the road to death's door. Nat. Rev. Mol. Cell Biol. 3, 401-410.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 401-410
-
-
Salvesen, G.S.1
Duckett, C.S.2
-
44
-
-
0033753206
-
The pattern of CPP32/caspase-3 expression reflects the biological behavior of the human pancreatic duct cell tumors
-
Satoh, K., Kaneko, K., Hirota, M., Toyota, T., and Shimosegawa, T. (2000). The pattern of CPP32/caspase-3 expression reflects the biological behavior of the human pancreatic duct cell tumors. Pancreas 21, 352-357.
-
(2000)
Pancreas
, vol.21
, pp. 352-357
-
-
Satoh, K.1
Kaneko, K.2
Hirota, M.3
Toyota, T.4
Shimosegawa, T.5
-
45
-
-
0023472472
-
Tricine-sodium dodecylsulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
-
Schägger, H., and von Jagow, G. (1987). Tricine-sodium dodecylsulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem. 166, 368-379.
-
(1987)
Anal. Biochem.
, vol.166
, pp. 368-379
-
-
Schägger, H.1
von Jagow, G.2
-
46
-
-
0033593201
-
A caspase-9 variant missing the catalytic site is an endogenous inhibitor of apoptosis
-
Seol, D.W., and Billiar, T.R. (1999). A caspase-9 variant missing the catalytic site is an endogenous inhibitor of apoptosis. J. Biol. Chem. 274, 2072-2076.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2072-2076
-
-
Seol, D.W.1
Billiar, T.R.2
-
47
-
-
0034194022
-
Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells
-
Shinoura, N., Muramatsu, Y., Yoshida, Y., Asai, A., Kirino, T., and Hamada, H. (2000). Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells. Exp. Cell Res. 256, 423-433.
-
(2000)
Exp. Cell Res.
, vol.256
, pp. 423-433
-
-
Shinoura, N.1
Muramatsu, Y.2
Yoshida, Y.3
Asai, A.4
Kirino, T.5
Hamada, H.6
-
48
-
-
0037291737
-
Mechanism of XIAP-mediated inhibition of caspase-9
-
Shiozaki, E.N., Chai, J., Rigotti, D.J., Riedl, S.J., Li, P., Srinivasula, S.M., Alnemri, E.S., Fairman, R., and Shi, Y. (2003). Mechanism of XIAP-mediated inhibition of caspase-9. Mol. Cell 11, 519-527.
-
(2003)
Mol. Cell
, vol.11
, pp. 519-527
-
-
Shiozaki, E.N.1
Chai, J.2
Rigotti, D.J.3
Riedl, S.J.4
Li, P.5
Srinivasula, S.M.6
Alnemri, E.S.7
Fairman, R.8
Shi, Y.9
-
49
-
-
0037028250
-
Loss of expression of death-inducing signaling complex (DISC) components in lung cancer cell lines and the influence of MYC amplification
-
Shivapurkar, N., Reddy, J., Matta, H., Sathyanarayana, U.G., Huang, C.X., Toyooka, S., Minna, J.D., Chaudhary, P.M., and Gazdar, A.F. (2002a). Loss of expression of death-inducing signaling complex (DISC) components in lung cancer cell lines and the influence of MYC amplification. Oncogene 21, 8510-8514.
-
(2002)
Oncogene
, vol.21
, pp. 8510-8514
-
-
Shivapurkar, N.1
Reddy, J.2
Matta, H.3
Sathyanarayana, U.G.4
Huang, C.X.5
Toyooka, S.6
Minna, J.D.7
Chaudhary, P.M.8
Gazdar, A.F.9
-
50
-
-
85047687948
-
Differential inactivation of caspase-8 in lung cancers
-
Shivapurkar, N., Toyooka, S., Eby, M.T., Huang, C.X., Sathyanarayana, U.G., Cunningham, H.T., Reddy, J.L., Brambilla, E., Takahashi, T., Minna, J.D., Chaudhary, P.M., and Gazdar, A.F. (2002b). Differential inactivation of caspase-8 in lung cancers. Cancer Biol. Ther. 1, 65-69.
-
(2002)
Cancer Biol. Ther.
, vol.1
, pp. 65-69
-
-
Shivapurkar, N.1
Toyooka, S.2
Eby, M.T.3
Huang, C.X.4
Sathyanarayana, U.G.5
Cunningham, H.T.6
Reddy, J.L.7
Brambilla, E.8
Takahashi, T.9
Minna, J.D.10
Chaudhary, P.M.11
Gazdar, A.F.12
-
51
-
-
0033601746
-
Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
-
Slee, E.A., Harte, M.T., Kluck, R.M., Wolf, B.B., Casiano, C.A., Newmeyer, D.D., Wang, H. G., Reed, J.C., Nicholson, D.W., Alnemri, E.S. et al. (1999). Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. J. Cell Biol. 144, 281-292.
-
(1999)
J. Cell Biol.
, vol.144
, pp. 281-292
-
-
Slee, E.A.1
Harte, M.T.2
Kluck, R.M.3
Wolf, B.B.4
Casiano, C.A.5
Newmeyer, D.D.6
Wang, H.G.7
Reed, J.C.8
Nicholson, D.W.9
Alnemri, E.S.10
-
52
-
-
0035831473
-
Executioner caspases-3, -6 and -7 perform distinct, non-redundant, roles during the demolition phase of apoptosis
-
Slee, E.A., Adrain, C., and Martin, S.J. (2001). Executioner caspases-3, -6 and -7 perform distinct, non-redundant, roles during the demolition phase of apoptosis. J. Biol. Chem. 276, 7320-7326.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 7320-7326
-
-
Slee, E.A.1
Adrain, C.2
Martin, S.J.3
-
53
-
-
0022186670
-
Measurement of protein using bicinchoninic acid
-
Smith, P.K., Krohn, R.I., Hermanson, G.T., Mallia, A.K., Gartner, F.H., Provenzano, M.D., Fujimoto, E.K., Goeke, N.M., Olson, B.J., and Klenk, D.C. (1985). Measurement of protein using bicinchoninic acid. Anal. Biochem. 150, 76-85.
-
(1985)
Anal. Biochem.
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
Gartner, F.H.5
Provenzano, M.D.6
Fujimoto, E.K.7
Goeke, N.M.8
Olson, B.J.9
Klenk, D.C.10
-
54
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
Soengas, M.S., Capodieci, P., Polsky, D., Mora, J., Esteller, M., Opitz-Araya, X., McCombie, R., Herman, J.G., Gerald, W.L., Lazebnik, Y.A. et al. (2001). Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature 409, 207-211.
-
(2001)
Nature
, vol.409
, pp. 207-211
-
-
Soengas, M.S.1
Capodieci, P.2
Polsky, D.3
Mora, J.4
Esteller, M.5
Opitz-Araya, X.6
McCombie, R.7
Herman, J.G.8
Gerald, W.L.9
Lazebnik, Y.A.10
-
55
-
-
0033104331
-
Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis
-
Srinivasula, S.M., Ahmad, M., Guo, Y., Zhan, Y., Lazebnik, Y., Fernandes-Alnemri, T., and Alnemri, E.S. (1999). Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis. Cancer Res. 59, 999-1002.
-
(1999)
Cancer Res.
, vol.59
, pp. 999-1002
-
-
Srinivasula, S.M.1
Ahmad, M.2
Guo, Y.3
Zhan, Y.4
Lazebnik, Y.5
Fernandes-Alnemri, T.6
Alnemri, E.S.7
-
56
-
-
0034615555
-
Caspases - Controlling intracellular signals by protease zymogen activation
-
Stennicke, H.R., and Salvesen, G.S. (2000). Caspases - controlling intracellular signals by protease zymogen activation. Biochim. Biophys. Acta 1477, 299-306.
-
(2000)
Biochim. Biophys. Acta
, vol.1477
, pp. 299-306
-
-
Stennicke, H.R.1
Salvesen, G.S.2
-
57
-
-
0032403126
-
IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs
-
Tamm, I., Wang, Y., Sausville, E., Scudiero, D.A., Vigna, N., Oltersdort, T., and Reed, J.C. (1998). IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res. 58, 5315-5320.
-
(1998)
Cancer Res.
, vol.58
, pp. 5315-5320
-
-
Tamm, I.1
Wang, Y.2
Sausville, E.3
Scudiero, D.A.4
Vigna, N.5
Oltersdort, T.6
Reed, J.C.7
-
58
-
-
0035879816
-
Expression of caspases-3, -6 and -8 and their relation to apoptosis in non-small cell lung carcinoma
-
Törmänen-Näpänkangas, U., Soini, Y., Kahlos, K., Kinnula, V., and Pääkkö, P. (2001). Expression of caspases-3, -6 and -8 and their relation to apoptosis in non-small cell lung carcinoma. Int. J. Cancer 93, 192-198.
-
(2001)
Int. J. Cancer
, vol.93
, pp. 192-198
-
-
Törmänen-Näpänkangas, U.1
Soini, Y.2
Kahlos, K.3
Kinnula, V.4
Pääkkö, P.5
-
59
-
-
0003425741
-
Histological typing of lung and pleural tumours
-
(Berlin, Germany: Springer Verlag)
-
Travis, W.D., Colby, T.V., Corrin, B., Shimosato, Y., and Brambilla, E. (1999). Histological typing of lung and pleural tumours (Berlin, Germany: Springer Verlag).
-
(1999)
-
-
Travis, W.D.1
Colby, T.V.2
Corrin, B.3
Shimosato, Y.4
Brambilla, E.5
-
60
-
-
19244376973
-
Apoptosis in gall-bladder carcinomas and dysplasias, its relation to the expression of caspases 3, 6 and 8 and apoptosis regulating proteins bcl-2, mcl-1 and bax
-
Turunen, N., Pääkkö, P., and Soini, Y. (2000). Apoptosis in gall-bladder carcinomas and dysplasias, its relation to the expression of caspases 3, 6 and 8 and apoptosis regulating proteins bcl-2, mcl-1 and bax. Histol. Histopathol. 15, 53-60.
-
(2000)
Histol. Histopathol.
, vol.15
, pp. 53-60
-
-
Turunen, N.1
Pääkkö, P.2
Soini, Y.3
-
61
-
-
0031770074
-
Apoptotic index and apoptosis influencing proteins bcl-2, mcl-1, bax and caspases 3, 6 and 8 in pancreatic carcinoma
-
Virkäjarvi, N., Pääkkö, P., and Soini, Y. (1998). Apoptotic index and apoptosis influencing proteins bcl-2, mcl-1, bax and caspases 3, 6 and 8 in pancreatic carcinoma. Histopathology 33, 432-439.
-
(1998)
Histopathology
, vol.33
, pp. 432-439
-
-
Virkäjarvi, N.1
Pääkkö, P.2
Soini, Y.3
-
62
-
-
0035117041
-
Loss of caspase-1 and caspase-3 protein expression in human prostate cancer
-
Winter, R.N., Kramer, A., Borkowski, A., and Kyprianou, N. (2001). Loss of caspase-1 and caspase-3 protein expression in human prostate cancer. Cancer Res. 61, 1227-1232.
-
(2001)
Cancer Res.
, vol.61
, pp. 1227-1232
-
-
Winter, R.N.1
Kramer, A.2
Borkowski, A.3
Kyprianou, N.4
-
63
-
-
0033393502
-
Cancer gene therapy using a pro-apoptotic gene, caspase-3
-
Yamabe, K., Shimizu, S., Ito, T., Yoshioka, Y., Nomura, M., Narita, M., Saito, I., Kanegae, Y., and Matsuda, H. (1999). Cancer gene therapy using a pro-apoptotic gene, caspase-3. Gene Ther. 6, 1952-1959.
-
(1999)
Gene Ther.
, vol.6
, pp. 1952-1959
-
-
Yamabe, K.1
Shimizu, S.2
Ito, T.3
Yoshioka, Y.4
Nomura, M.5
Narita, M.6
Saito, I.7
Kanegae, Y.8
Matsuda, H.9
-
64
-
-
0037442965
-
Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: Therapeutic effect of a novel polyarginine-conjugated Smac peptide
-
Yang, L., Mashima, T., Sato, S., Mochizuki, M., Sakamoto, H., Yamori, T., Oh-Hara, T., and Tsuruo, T. (2003). Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: Therapeutic effect of a novel polyarginine-conjugated Smac peptide. Cancer Res. 63, 831-837.
-
(2003)
Cancer Res.
, vol.63
, pp. 831-837
-
-
Yang, L.1
Mashima, T.2
Sato, S.3
Mochizuki, M.4
Sakamoto, H.5
Yamori, T.6
Oh-Hara, T.7
Tsuruo, T.8
-
65
-
-
0037424261
-
Regulation of the Apaf-1/caspase-9 apoptosome by caspase-3 and XIAP
-
Zou, H., Yang, R., Hao, J., Wang, J., Sun, C., Fesik, S.W., Wu, J.C., Tomaselli, K.J., and Armstrong, R.C. (2003). Regulation of the Apaf-1/caspase-9 apoptosome by caspase-3 and XIAP. J. Biol. Chem. 278, 8091-8098.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8091-8098
-
-
Zou, H.1
Yang, R.2
Hao, J.3
Wang, J.4
Sun, C.5
Fesik, S.W.6
Wu, J.C.7
Tomaselli, K.J.8
Armstrong, R.C.9
|