Genomic analyses of anaerobically induced genes in Saccharomyces cerevisiae: Functional roles of Rox1 and other factors in mediating the anoxic response

Journal of Bacteriology

Volumn 184, Issue 1, 2002, Pages 250-265

  Kwast, K E ^a   Lai, L C ^a   Menda, N ^a   James III, D T ^a   Aref, S ^a   Burke, P V ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACONITATE HYDRATASE; ALDEHYDE DEHYDROGENASE; CITRATE SYNTHASE; CYTOCHROME C OXIDASE; DIHYDROLIPOAMIDE DEHYDROGENASE; DNA BINDING PROTEIN; FUMARATE HYDRATASE; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; HEME; ISOCITRATE DEHYDROGENASE; MESSENGER RNA; OXOGLUTARATE DEHYDROGENASE; OXYGEN; PROTEIN ROX1; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; SUCCINATE DEHYDROGENASE; TRANS ACTING FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR UPC2; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG;

ANAEROBIC METABOLISM; ARTICLE; CARBOHYDRATE METABOLISM; CELL HYPOXIA; CELL WALL; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE INDUCTION; GENOME; LIPID METABOLISM; NONHUMAN; OPEN READING FRAME; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; REGULON; SACCHAROMYCES CEREVISIAE; STRESS;

ANAEROBIOSIS; CARBOHYDRATE METABOLISM; CELL WALL; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; GENOME, FUNGAL; HEME; LIPID METABOLISM; MODELS, BIOLOGICAL; OXYGEN; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANS-ACTIVATORS;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0036135461     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.184.1.250-265.2002     Document Type: Article

References (85)

1. Reciprocal regulation of anaerobic and aerobic cell wall mannoprotein gene expression in Saccharomyces cerevisiae
2. Regulatory mechanisms controlling expression of the DAN/TIR mannoprotein genes during anaerobic remodeling of the cell wall in Saccharomyces cerevisiae
3. Global gene expression during short-term ethanol stress in Saccharomyces cerevisiae
4. Anaerobic nutrition of Saccharomyces cerevisiae. I. Ergosterol requirement for growth in a defined medium
5. Anaerobic nutrition of Saccharomyces cerevisiae. II. Unsaturated fatty acid requirement for growth in defined medium
6. The two isoenzymes for yeast NAD+-dependent glycerol 3-phosphate dehydrogenase encoded by GPD1 and GPD2 have distinct roles in osmoadaptation and redox regulation
7. Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae
8. The Rox1 repressor of the Saccharomyces cerevisiae hypoxic genes is a specific DNA-binding protein with a high-mobility-group motif
9. Two endoplasmic reticulum (ER) membrane proteins that facilitate ER-to-Golgi transport of glycosylphosphatidylinositol-anchored proteins
10. The Saccharomyces cerevisiae mevalonate diphosphate decarboxylase is essential for viability, and a single Leu-to-Pro mutation in a conserved sequence leads to thermosensitivity
11. A Rox1-independent hypoxic pathway in yeast. Antagonistic action of the repressor Ord1 and activator Yap1 for hypoxic expression of the SRP1/TIR1 gene
12. Positive regulation of the LPD1 gene of Saccharomyces cerevisiae by the HAP2/HAP3/HAP4 activation system
13. Oxygen dependence of expression of cytochrome c and cytochrome c oxidase genes in S. cerevisiae
14. A fermentor system for regulating oxygen at low concentrations in cultures of Saccharomyces cerevisiae
15. Effects of oxygen concentration on the expression of cytochrome c and cytochrome c oxidase genes in yeast
16. Phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and interrelationship with other metabolic processes
17. In silico identification of glycosyl-phosphatidylinositol-anchored plasma-membrane and cell wall proteins of Saccharomyces cerevisiae
18. Pregnenolone esterification in Saccharomyces cerevisiae. A potential detoxification mechanism
19. Remodeling of yeast genome expression in response to environmental changes
20. Regulatory elements that control transcription activation and unsaturated fatty acid-mediated repression of the Saccharomyces cerevisiae OLE1 gene
21. Induction and repression of DAN1 and the family of anaerobic mannoprotein genes in Saccharomyces cerevisiae occurs through a complex array of regulatory sites
22. A mutation in a purported regulatory gene affects control of sterol uptake in Saccharomyces cerevisiae
23. Two nonidentical forms of subunit V are functional in yeast cytochrome c oxidase
24. A protein kinase antigenically related to pp60v-src possibly involved in yeast cell cycle control: Positive in vivo regulation by sterol
25. Characterization of the DNA binding and bending HMG domain of the yeast hypoxic repressor Rox1
26. Multiple elements and auto-repression regulate Rox1, a repressor of hypoxic genes in Saccharomyces cerevisiae
27. Mutational analysis of Rox1, a DNA-bending repressor of hypoxic genes in Saccharomyces cerevisiae
28. The anatomy of a hypoxic operator in Saccharomyces cerevisiae
29. Exploring the metabolic and genetic control of gene expression on a genomic scale
30. Global regulation of mitochondrial biogenesis in Saccharomyces cerevisiae
31. Regulation by low temperatures and anaerobiosis of a yeast gene specifying a putative GPI-anchored plasma membrane protein
32. Genome-wide responses to mitochondrial dysfunction
33. Identification of regulatory regions within the Ty1 transposable element that regulate iso-2-cytochrome c production in the CYC7-H2 yeast mutant
34. The Acyl-CoA synthetases encoded within FAA1 and FAA4 in Saccharomyces cerevisiae function as components of the fatty acid transport system linking import, activation, and intracellular utilization
35. Reserve carbohydrates metabolism in the yeast Saccharomyces cerevisiae
36. Molecular mechanism of the multiple regulation of the Saccharomyces cerevisiae ATF1 gene encoding alcohol acetyltransferase
37. Transcriptional co-regulation of Saccharomyces cerevisiae alcohol acetyltransferase gene, ATF1 and delta-9 fatty acid desaturase gene, OLE1 by unsaturated fatty acids
38. Genomic expression programs in the response of yeast cells to environmental changes
39. Control of mitochondrial and cellular respiration by oxygen
40. Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins
41. Chitin synthases in yeast and fungi
42. Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae
43. Genome-wide analysis of gene expression regulated by the yeast cell wall integrity signaling pathway
44. Roles of transcription factor Mot3 and chromatin in repression of the hypoxic gene ANB1 in yeast
45. Rox1 mediated repression. Oxygen dependent repression in yeast
46. HAP1 and ROX1 form a regulatory pathway in the repression of HEM13 transcription in Saccharomyces cerevisiae
47. Global and specific translational regulation in the genomic response of Saccharomyces cerevisiae to a rapid transfer from a fermentable to a nonfermentable carbon source
48. REO1 and ROX1 are alleles of the same gene which encodes a transcriptional repressor of hypoxic genes in Saccharomyces cerevisiae
49. Oxygen sensing and the transcriptional regulation of oxygen-responsive genes in yeast
50. Oxygen sensing in yeast: Evidence for the involvement of the respiratory chain in regulating the transcription of a subset of hypoxic genes
51. Tetrapyrrole and heme biosynthesis in the yeast Saccharomyces cerevisiae
52. Biodiversity of the P450 catalytic cycle: Yeast cytochrome b5/NADH cytochrome b5 reductase complex efficiently drives the entire sterol 14-demethylation (CYP51) reaction
53. Dual targeting of Osh1p, a yeast homologue of oxysterol-binding protein, to both the Golgi and the nucleus-vacuole junction
54. Mitochondrial ABC transporters
55. A transcriptional switch in the expression of yeast tricarboxylic acid cycle genes in response to a reduction or loss of respiratory function
56. A hypoxic consensus operator and a constitutive activation region regulate the ANB1 gene of Saccharomyces cerevisiae
57. Oxygen regulation of anaerobic and aerobic genes mediated by a common factor in yeast
58. ROX1 encodes a heme-induced repression factor regulating ANB1 and CYC7 of Saccharomyces cerevisiae
59. Ability for anaerobic growth is not sufficient for development of the petite phenotype in Saccharomyces kluyveri
60. SUT1 is a putative Zn[11]2Cys6-transcription factor whose upregulation enhances both sterol uptake and synthesis in aerobically growing Saccharomyces cerevisiae cells
61. Flux distributions in anaerobic, glucose-limited continuous cultures of Saccharomyces cerevisiae
62. The mitochondrial genotype can influence nuclear gene expression in yeast
63. Effects of various types of stress on the metabolism of reserve carbohydrates in Saccharomyces cerevisiae: Genetic evidence for a stress-induced recycling of glycogen and trehalose
64. Origin of the duplicated regions in the yeast genomes
65. Organization of the regulatory region of the yeast CYC7 gene: Multiple factors are involved in regulation
66. Sut1p interaction with Cyc8p(Ssn6p) relieves hypoxic genes from Cyc8p-Tup1p repression in Saccharomyces cerevisiae
67. The transcriptional response of Saccharomyces cerevisiae to osmotic shock. Hot1p and Msn2p/Msn4p are required for the induction of subsets of high osmolarity glycerol pathway-dependent genes
68. Structure and regulation of KGD1, the structural gene for yeast alpha-ketoglutarate dehydrogenase
69. Transcriptional control of AAC3 gene encoding mitochondrial ADP/ATP translocator in Saccharomyces cerevisiae by oxygen, heme and ROX1 factor
70. Updated map of duplicated regions in the yeast genome
71. Getting started with yeast
72. Chromosome mapping of the CYC7 gene determining yeast iso-2-cytochrome c: Structural and regulatory regions
73. Turning genes off by Ssn6-Tup1: A conserved system of transcriptional repression in eukaryotes
74. Cell wall dynamics in yeast
75. Sterol metabolism and ERG2 gene regulation in the yeast Saccharomyces cerevisiae
76. Genome-wide transcriptional analysis of aerobic and anaerobic chemostat cultures of Saccharomyces cerevisiae
77. Positive and negative transcriptional control by heme of genes encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase in Saccharomyces cerevisiae
78. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
79. Differential regulation of the two genes encoding Saccharomyces cerevisiae cytochrome c oxidase subunit V by heme and the HAP2 and REO1 genes
80. Multiple regulatory elements control expression of the gene encoding the Saccharomyces cerevisiae cytochrome P450, lanosterol 14 alpha-demethylase (ERG11)
81. Identification and characterization of a low oxygen response element involved in the hypoxic induction of a family of Saccharomyces cerevisiae genes. Implications for the conservation of oxygen sensing in eukaryotes
82. Oxygen requirements of yeasts
83. Regulation of hypoxic gene expression in yeast
84. Regulation of gene expression by oxygen in Saccharomyces cerevisiae
85. Elements involved in oxygen regulation of the Saccharomyces cerevisiae CYC7 gene