메뉴 건너뛰기




Volumn 23, Issue , 2005, Pages 651-682

Understanding presentation of viral antigens to CD8+ T cells in vivo: The key to rational vaccine design

Author keywords

Antigen presentation; CTL; MHC; Virus

Indexed keywords

CD8 ANTIGEN; MEMBRANE PROTEIN; VACCINE; VIRUS ANTIGEN; VIRUS PROTEIN;

EID: 17644393143     PISSN: 07320582     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.immunol.23.021704.115702     Document Type: Review
Times cited : (183)

References (105)
  • 2
    • 0021829024 scopus 로고
    • The generative grammar of the immune system
    • Jerne NK. 1985. The generative grammar of the immune system. Science 229:1057-59
    • (1985) Science , vol.229 , pp. 1057-1059
    • Jerne, N.K.1
  • 3
    • 0030176270 scopus 로고    scopus 로고
    • Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response
    • Sykulev Y, Joo M, Vturina I, Tsomides TJ, Eisen HN. 1996. Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response. Immunity 4:565-11
    • (1996) Immunity , vol.4 , pp. 565-511
    • Sykulev, Y.1    Joo, M.2    Vturina, I.3    Tsomides, T.J.4    Eisen, H.N.5
  • 5
    • 0036852231 scopus 로고    scopus 로고
    • Viral interference with antigen presentation
    • Yewdell JW, Hill AB. 2002. Viral interference with antigen presentation. Nat. Immunol. 3:1019-25
    • (2002) Nat. Immunol. , vol.3 , pp. 1019-1025
    • Yewdell, J.W.1    Hill, A.B.2
  • 6
    • 0028955449 scopus 로고
    • Effect of TAP on the generation and intracellular trafficking of peptide-receptive major histocompatibility complex class I molecules
    • Day PM, Esquivel F, Lukszo J, Bennink JR, Yewdell JW. 1995. Effect of TAP on the generation and intracellular trafficking of peptide-receptive major histocompatibility complex class I molecules. Immunity 2:137-47
    • (1995) Immunity , vol.2 , pp. 137-147
    • Day, P.M.1    Esquivel, F.2    Lukszo, J.3    Bennink, J.R.4    Yewdell, J.W.5
  • 7
    • 0029993103 scopus 로고    scopus 로고
    • Roles of proteosomes, transporter for antigen presentation (TAP), and b2-microglobulin in the processing of bacterial or participate antigens via an alternate class I MHC processing pathway
    • Song R, Harding CV. 1996. Roles of proteosomes, transporter for antigen presentation (TAP), and b2-microglobulin in the processing of bacterial or participate antigens via an alternate class I MHC processing pathway. J. Immunol. 156:4182-90
    • (1996) J. Immunol. , vol.156 , pp. 4182-4190
    • Song, R.1    Harding, C.V.2
  • 10
    • 0035963379 scopus 로고    scopus 로고
    • Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction
    • Ochsenbein AF, Sierro S, Odermatt B, Pericin M, Karrer U, et al. 2001. Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction. Nature 411:1058-64
    • (2001) Nature , vol.411 , pp. 1058-1064
    • Ochsenbein, A.F.1    Sierro, S.2    Odermatt, B.3    Pericin, M.4    Karrer, U.5
  • 11
    • 0025991258 scopus 로고
    • Macrophages as accessory cells for class I MHC-restricted immune responses
    • Debrick JE, Campbell PA, Staerz UD. 1991. Macrophages as accessory cells for class I MHC-restricted immune responses. J. Immunol. 147:2846-51
    • (1991) J. Immunol. , vol.147 , pp. 2846-2851
    • Debrick, J.E.1    Campbell, P.A.2    Staerz, U.D.3
  • 13
    • 0033522179 scopus 로고    scopus 로고
    • Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen
    • Sigal LJ, Crotty S, Andino R, Rock KL. 1999. Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen. Nature 398:77-80
    • (1999) Nature , vol.398 , pp. 77-80
    • Sigal, L.J.1    Crotty, S.2    Andino, R.3    Rock, K.L.4
  • 14
    • 0036906526 scopus 로고    scopus 로고
    • Langerhans cells renew in the skin throughout life under steady-state conditions
    • Merad M, Manz MG, Karsunky H, Wagers A, Peters W, et al. 2002. Langerhans cells renew in the skin throughout life under steady-state conditions. Nat. Immunol. 3:1135-41
    • (2002) Nat. Immunol. , vol.3 , pp. 1135-1141
    • Merad, M.1    Manz, M.G.2    Karsunky, H.3    Wagers, A.4    Peters, W.5
  • 15
    • 0028208970 scopus 로고
    • TAP (transporter associated with antigen processing)-independent presentation of endogenously synthesized peptides is enhanced by endoplasmic reticulum insertion sequences located at the amino- but not carboxyl-terminus of the peptide
    • Bacik I, Cox JH, Anderson R, Yewdell JW, Bennink JR. 1994. TAP (transporter associated with antigen processing)-independent presentation of endogenously synthesized peptides is enhanced by endoplasmic reticulum insertion sequences located at the amino- but not carboxyl-terminus of the peptide. J. Immunol. 152:381-87
    • (1994) J. Immunol. , vol.152 , pp. 381-387
    • Bacik, I.1    Cox, J.H.2    Anderson, R.3    Yewdell, J.W.4    Bennink, J.R.5
  • 16
    • 0034675955 scopus 로고    scopus 로고
    • Requirements for bone marrow-derived antigen-presenting cells in priming cytotoxic T cell responses to intracellular pathogens
    • Lenz LL, Butz EA, Bevan MJ. 2000. Requirements for bone marrow-derived antigen-presenting cells in priming cytotoxic T cell responses to intracellular pathogens. J. Exp. Med. 192:1135-42
    • (2000) J. Exp. Med. , vol.192 , pp. 1135-1142
    • Lenz, L.L.1    Butz, E.A.2    Bevan, M.J.3
  • 17
    • 0034676087 scopus 로고    scopus 로고
    • Bone marrow-derived antigen-presenting cells are required for the generation of cytotoxic T lymphocyte responses to viruses and use transporter associated with antigen presentation (TAP)-dependent and -independent pathways of antigen presentation
    • Sigal LJ, Rock KL. 2000. Bone marrow-derived antigen-presenting cells are required for the generation of cytotoxic T lymphocyte responses to viruses and use transporter associated with antigen presentation (TAP)-dependent and -independent pathways of antigen presentation. J. Exp. Med. 192:1143-50
    • (2000) J. Exp. Med. , vol.192 , pp. 1143-1150
    • Sigal, L.J.1    Rock, K.L.2
  • 19
    • 0036518287 scopus 로고    scopus 로고
    • Mouse and human dendritic cell subtypes
    • Shortman K, Liu YJ. 2002. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2:151-61
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 151-161
    • Shortman, K.1    Liu, Y.J.2
  • 20
    • 2942541735 scopus 로고    scopus 로고
    • Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens
    • Heath WR, Belz GT, Behrens GM, Smith CM, Forehan SP, et al. 2004. Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens. Immunol. Rev. 199:9-26
    • (2004) Immunol. Rev. , vol.199 , pp. 9-26
    • Heath, W.R.1    Belz, G.T.2    Behrens, G.M.3    Smith, C.M.4    Forehan, S.P.5
  • 21
    • 0242668754 scopus 로고    scopus 로고
    • + dendritic cells are preferentially involved in CTL priming after footpad infection with herpes simplex virus-12
    • + dendritic cells are preferentially involved in CTL priming after footpad infection with herpes simplex virus-12. J. Immunol. 170:4437-40
    • (2003) J. Immunol. , vol.170 , pp. 4437-4440
    • Smith, C.M.1    Belz, G.T.2    Wilson, N.S.3    Villadangos, J.A.4    Shortman, K.5
  • 24
    • 2942593821 scopus 로고    scopus 로고
    • Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus
    • Belz GT, Smith CM, Kleinen L, Reading P, Brooks A, et al. 2004. Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus. Proc. Natl. Acad. Sci. USA 101:8670-75
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 8670-8675
    • Belz, G.T.1    Smith, C.M.2    Kleinen, L.3    Reading, P.4    Brooks, A.5
  • 25
    • 3142750530 scopus 로고    scopus 로고
    • + T cells during pulmonary influenza virus infection
    • + T cells during pulmonary influenza virus infection. J. Immunol. 173:1209-18
    • (2004) J. Immunol. , vol.173 , pp. 1209-1218
    • Lawrence, C.W.1    Braciale, T.J.2
  • 26
    • 0032714070 scopus 로고    scopus 로고
    • The use of carboxyfluorescein diacetate succinimidyl ester to determine the site, duration and cell type responsible for antigen presentation in vivo
    • Mintern J, Li M, Davey GM, Blanas E, Kurts C, et al. 1999. The use of carboxyfluorescein diacetate succinimidyl ester to determine the site, duration and cell type responsible for antigen presentation in vivo. Immunol. Cell Biol. 77:539-43
    • (1999) Immunol. Cell Biol. , vol.77 , pp. 539-543
    • Mintern, J.1    Li, M.2    Davey, G.M.3    Blanas, E.4    Kurts, C.5
  • 27
    • 0037332073 scopus 로고    scopus 로고
    • Accelerated migration of respiratory dendritic cells to the regional lymph nodes is limited to the early phase of pulmonary infection
    • Legge KL, Braciale TJ. 2003. Accelerated migration of respiratory dendritic cells to the regional lymph nodes is limited to the early phase of pulmonary infection. Immunity 18:265-77
    • (2003) Immunity , vol.18 , pp. 265-277
    • Legge, K.L.1    Braciale, T.J.2
  • 31
    • 0034693949 scopus 로고    scopus 로고
    • Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex
    • Gretz JE, Norbury CC, Anderson AO, Proudfoot AE, Shaw S. 2000. Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex. J. Exp. Med. 192:1425-40
    • (2000) J. Exp. Med. , vol.192 , pp. 1425-1440
    • Gretz, J.E.1    Norbury, C.C.2    Anderson, A.O.3    Proudfoot, A.E.4    Shaw, S.5
  • 33
    • 0034130060 scopus 로고    scopus 로고
    • Accessing complexity: The dynamics of virus-specific T cell responses
    • Doherty PC, Christensen JP. 2000. Accessing complexity: the dynamics of virus-specific T cell responses. Annu. Rev. Immunol. 18:561-92
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 561-592
    • Doherty, P.C.1    Christensen, J.P.2
  • 35
    • 0037080026 scopus 로고    scopus 로고
    • Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus 1
    • Coles RM, Mueller SN, Heath WR, Carbone FR, Brooks AG. 2002. Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus 1. J. Immunol. 168:834-38
    • (2002) J. Immunol. , vol.168 , pp. 834-838
    • Coles, R.M.1    Mueller, S.N.2    Heath, W.R.3    Carbone, F.R.4    Brooks, A.G.5
  • 36
    • 0347717903 scopus 로고    scopus 로고
    • T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
    • Mempel TR, Henrickson SE, Von Andrian UH. 2004. T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 427:154-59
    • (2004) Nature , vol.427 , pp. 154-159
    • Mempel, T.R.1    Henrickson, S.E.2    Von Andrian, U.H.3
  • 37
    • 0023847926 scopus 로고
    • Cells process exogenous proteins for recognition by cytotoxic T lymphocytes
    • Yewdell JW, Bennink JR, Hosaka Y. 1988. Cells process exogenous proteins for recognition by cytotoxic T lymphocytes. Science 239:637-40
    • (1988) Science , vol.239 , pp. 637-640
    • Yewdell, J.W.1    Bennink, J.R.2    Hosaka, Y.3
  • 38
    • 0025755277 scopus 로고
    • Class I MHC-restricted cytotoxic T lymphocyte recognition of cells infected with human cytomegalovirus does not require endogenous viral gene expression
    • Riddell SR, Rabin M, Geballe AP, Britt WJ, Greenberg PD. 1991. Class I MHC-restricted cytotoxic T lymphocyte recognition of cells infected with human cytomegalovirus does not require endogenous viral gene expression. J. Immunol. 146:2795-804
    • (1991) J. Immunol. , vol.146 , pp. 2795-2804
    • Riddell, S.R.1    Rabin, M.2    Geballe, A.P.3    Britt, W.J.4    Greenberg, P.D.5
  • 39
    • 0017126775 scopus 로고
    • Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay
    • Bevan MJ. 1976. Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J. Exp. Med. 143:1283-88
    • (1976) J. Exp. Med. , vol.143 , pp. 1283-1288
    • Bevan, M.J.1
  • 40
    • 0033062377 scopus 로고    scopus 로고
    • + T cell responses to infectious agents, tumors, transplants, and vaccines
    • + T cell responses to infectious agents, tumors, transplants, and vaccines. Adv. Immunol. 73:1-77
    • (1999) Adv. Immunol. , vol.73 , pp. 1-77
    • Yewdell, J.W.1    Norbury, C.C.2    Bennink, J.R.3
  • 41
    • 0036203799 scopus 로고    scopus 로고
    • Intercellular transfer of antigen-presenting cell determinants onto T cells: Molecular mechanisms and biological significance
    • Hudrisier D, Bongrand P. 2002. Intercellular transfer of antigen-presenting cell determinants onto T cells: molecular mechanisms and biological significance. FASEB J. 16:477-86
    • (2002) FASEB J. , vol.16 , pp. 477-486
    • Hudrisier, D.1    Bongrand, P.2
  • 42
    • 0033074360 scopus 로고    scopus 로고
    • + dendritic cells generate an immune response after subcutaneous injection without homing to the draining lymph node
    • + dendritic cells generate an immune response after subcutaneous injection without homing to the draining lymph node. J. Exp. Med. 189:593-98
    • (1999) J. Exp. Med. , vol.189 , pp. 593-598
    • Smith, A.L.1    Fazekas De St. Groth, B.2
  • 45
    • 0036737779 scopus 로고    scopus 로고
    • On cross-priming of MHC class I-specific CTL: Rule or exception?
    • Zinkernagel RM. 2002. On cross-priming of MHC class I-specific CTL: rule or exception? Eur. J. Immunol. 32:2385-92
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2385-2392
    • Zinkernagel, R.M.1
  • 47
    • 6344284232 scopus 로고    scopus 로고
    • + T cell responses to influenza A virus: Roles for cross-presentation and lysis-independent immunodomination
    • + T cell responses to influenza A virus: roles for cross-presentation and lysis-independent immunodomination. J. Immunol. 173:5021-27
    • (2004) J. Immunol. , vol.173 , pp. 5021-5027
    • Chen, W.1    Pang, K.2    Masterman, K.G.3    Basta, D.N.4    Hornung, F.5
  • 49
    • 0035871709 scopus 로고    scopus 로고
    • Cutting edge: Recombinant adenoviruses induce CD8 T cell responses to an inserted protein whose expression is limited to nonimmune cells
    • Prasad SA, Norbury CC, Chen W, Bennink JR, Yewdell JW. 2001. Cutting edge: recombinant adenoviruses induce CD8 T cell responses to an inserted protein whose expression is limited to nonimmune cells. J. Immunol. 166:4809-12
    • (2001) J. Immunol. , vol.166 , pp. 4809-4812
    • Prasad, S.A.1    Norbury, C.C.2    Chen, W.3    Bennink, J.R.4    Yewdell, J.W.5
  • 50
    • 0025179012 scopus 로고
    • Recombinant vaccinia viruses as vectors for studying T lymphocyte specificity and function
    • Bennink JR, Yewdell JW. 1990. Recombinant vaccinia viruses as vectors for studying T lymphocyte specificity and function. Curr. Top. Microbiol. Immunol. 163:153-84
    • (1990) Curr. Top. Microbiol. Immunol. , vol.163 , pp. 153-184
    • Bennink, J.R.1    Yewdell, J.W.2
  • 51
    • 0022871271 scopus 로고
    • Temporal regulation of influenza hemagglutinin expression in vaccinia virus recombinants and effects on the immune response
    • Coupar BEH, Andrew ME, Both GW, Boyle DB. 1986. Temporal regulation of influenza hemagglutinin expression in vaccinia virus recombinants and effects on the immune response. Eur. J. Immunol. 16:1479-87
    • (1986) Eur. J. Immunol. , vol.16 , pp. 1479-1487
    • Coupar, B.E.H.1    Andrew, M.E.2    Both, G.W.3    Boyle, D.B.4
  • 52
    • 0030915310 scopus 로고    scopus 로고
    • Antigen expression by dendritic cells correlates with the therapeutic effectiveness of a model recombinant poxvirus tumor vaccine
    • Bronte V, Carroll MW, Goletz TJ, Wang M, Overwijk WW, et al. 1997. Antigen expression by dendritic cells correlates with the therapeutic effectiveness of a model recombinant poxvirus tumor vaccine. Proc. Natl. Acad. Sci. USA 94:3183-88
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3183-3188
    • Bronte, V.1    Carroll, M.W.2    Goletz, T.J.3    Wang, M.4    Overwijk, W.W.5
  • 54
    • 0242331619 scopus 로고    scopus 로고
    • Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens
    • Ackerman AL, Kyritsis C, Tampe R, Cresswell P. 2003. Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens. Proc. Natl. Acad. Sci. USA 100:12889-94
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 12889-12894
    • Ackerman, A.L.1    Kyritsis, C.2    Tampe, R.3    Cresswell, P.4
  • 57
    • 4143146210 scopus 로고    scopus 로고
    • Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo
    • Shen L, Sigal LJ, Boes M, Rock KL. 2004. Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo. Immunity 21:155-65
    • (2004) Immunity , vol.21 , pp. 155-165
    • Shen, L.1    Sigal, L.J.2    Boes, M.3    Rock, K.L.4
  • 58
    • 0036644562 scopus 로고    scopus 로고
    • The murine cytomegalovirus immunomodulatory gene m152 prevents recognition of infected cells by M45-specific CTL but does not alter the immunodominance of the M45-specific CD8 T cell response in vivo
    • Gold MC, Munks MW, Wagner M, Koszinowski UH, Hill AB, Fling SP. 2002. The murine cytomegalovirus immunomodulatory gene m152 prevents recognition of infected cells by M45-specific CTL but does not alter the immunodominance of the M45-specific CD8 T cell response in vivo. J. Immunol. 169:359-65
    • (2002) J. Immunol. , vol.169 , pp. 359-365
    • Gold, M.C.1    Munks, M.W.2    Wagner, M.3    Koszinowski, U.H.4    Hill, A.B.5    Fling, S.P.6
  • 59
    • 0346655207 scopus 로고    scopus 로고
    • Cytomegalovirus misleads its host by priming of CD8 T cells specific for an epitope not presented in infected tissues
    • Holtappels R, Podlech J, Pahl-Seibert MF, Julch M, Thomas D, et al. 2004. Cytomegalovirus misleads its host by priming of CD8 T cells specific for an epitope not presented in infected tissues. J. Exp. Med. 199:131-36
    • (2004) J. Exp. Med. , vol.199 , pp. 131-136
    • Holtappels, R.1    Podlech, J.2    Pahl-Seibert, M.F.3    Julch, M.4    Thomas, D.5
  • 60
    • 0033900029 scopus 로고    scopus 로고
    • Macrophages escape inhibition of major histocompatibility complex class I-dependent antigen presentation by cytomegalovirus
    • Hengel H, Reusch U, Geginat G, Holtappels R, Ruppert T, et al. 2000. Macrophages escape inhibition of major histocompatibility complex class I-dependent antigen presentation by cytomegalovirus. J. Virol. 74:7861-68
    • (2000) J. Virol. , vol.74 , pp. 7861-7868
    • Hengel, H.1    Reusch, U.2    Geginat, G.3    Holtappels, R.4    Ruppert, T.5
  • 62
    • 0031414705 scopus 로고    scopus 로고
    • + T cell responses to EBV EBNA1: HLA class I presentation of the (Gly-Ala)-containing protein requires exogenous processing
    • + T cell responses to EBV EBNA1: HLA class I presentation of the (Gly-Ala)-containing protein requires exogenous processing. Immunity 7:791-802
    • (1997) Immunity , vol.7 , pp. 791-802
    • Blake, N.1    Lee, S.2    Redchenko, I.3    Thomas, W.4    Steven, N.5
  • 63
    • 2542446376 scopus 로고    scopus 로고
    • CD8 T cell recognition of endogenously expressed Epstein-Barr virus nuclear antigen 1
    • Lee SP, Brooks JM, Al-Jarrah H, Thomas WA, Haigh TA, et al. 2004. CD8 T cell recognition of endogenously expressed Epstein-Barr virus nuclear antigen 1. J. Exp. Med. 199:1409-20
    • (2004) J. Exp. Med. , vol.199 , pp. 1409-1420
    • Lee, S.P.1    Brooks, J.M.2    Al-Jarrah, H.3    Thomas, W.A.4    Haigh, T.A.5
  • 64
    • 0041971307 scopus 로고    scopus 로고
    • Self-inhibition of synthesis and antigen presentation by Epstein-Barr virus-encoded EBNA1
    • Yin Y, Manoury B, Fahraeus R. 2003. Self-inhibition of synthesis and antigen presentation by Epstein-Barr virus-encoded EBNA1. Science 301:1371-74
    • (2003) Science , vol.301 , pp. 1371-1374
    • Yin, Y.1    Manoury, B.2    Fahraeus, R.3
  • 66
    • 0042887514 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear antigen 1 (EBNA1) induced cytotoxicity in epithelial cells is associated with EBNA1 degradation and processing
    • Jones RJ, Smith LJ, Dawson CW, Haigh T, Blake NW, Young LS. 2003. Epstein-Barr virus nuclear antigen 1 (EBNA1) induced cytotoxicity in epithelial cells is associated with EBNA1 degradation and processing. Virology 313:663-76
    • (2003) Virology , vol.313 , pp. 663-676
    • Jones, R.J.1    Smith, L.J.2    Dawson, C.W.3    Haigh, T.4    Blake, N.W.5    Young, L.S.6
  • 68
    • 0242539823 scopus 로고    scopus 로고
    • Control of dendritic cell cross-presentation by the major histocompatibility complex class I cytoplasmic domain
    • Lizée G, Basha G, Tiong J, Julien JP, Tian M, et al. 2003. Control of dendritic cell cross-presentation by the major histocompatibility complex class I cytoplasmic domain. Nat. Immunol. 4:1065-73
    • (2003) Nat. Immunol. , vol.4 , pp. 1065-1073
    • Lizée, G.1    Basha, G.2    Tiong, J.3    Julien, J.P.4    Tian, M.5
  • 69
    • 0030849769 scopus 로고    scopus 로고
    • Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody
    • Porgador A, Yewdell JW, Deng Y, Bennink JR, Germain RN. 1997. Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody. Immunity 6:715-26
    • (1997) Immunity , vol.6 , pp. 715-726
    • Porgador, A.1    Yewdell, J.W.2    Deng, Y.3    Bennink, J.R.4    Germain, R.N.5
  • 71
    • 0036214288 scopus 로고    scopus 로고
    • Interaction of heat shock proteins with peptides and antigen presenting cells: Chaperoning of the innate and adaptive immune responses
    • Srivastava P. 2002. Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses. Annu. Rev. Immunol. 20:395-425
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 395-425
    • Srivastava, P.1
  • 72
    • 1542357672 scopus 로고    scopus 로고
    • Cellular protein is the source of cross-priming antigen in vivo
    • Shen L, Rock KL. 2004. Cellular protein is the source of cross-priming antigen in vivo. Proc. Natl. Acad. Sci. USA 101:3035-40
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 3035-3040
    • Shen, L.1    Rock, K.L.2
  • 74
    • 0037342270 scopus 로고    scopus 로고
    • Quantitating protein synthesis, degradation, and endogenous antigen processing
    • Princiotta MF, Finzi D, Qian SB, Gibbs J, Schuchmann S, et al. 2003. Quantitating protein synthesis, degradation, and endogenous antigen processing. Immunity 18:343-54
    • (2003) Immunity , vol.18 , pp. 343-354
    • Princiotta, M.F.1    Finzi, D.2    Qian, S.B.3    Gibbs, J.4    Schuchmann, S.5
  • 75
    • 0344585516 scopus 로고    scopus 로고
    • Cutting edge: Efficient MHC class I cross-presentation during early vaccinia infection requires the transfer of proteasomal intermediates between antigen donor and presenting cells
    • Serna A, Ramirez MC, Soukhanova A, Sigal LJ. 2003. Cutting edge: efficient MHC class I cross-presentation during early vaccinia infection requires the transfer of proteasomal intermediates between antigen donor and presenting cells. J. Immunol. 171:5668-72
    • (2003) J. Immunol. , vol.171 , pp. 5668-5672
    • Serna, A.1    Ramirez, M.C.2    Soukhanova, A.3    Sigal, L.J.4
  • 77
    • 0037011072 scopus 로고    scopus 로고
    • GRP94 (gp96) and GRP94 N-terminal geldanamycin binding domain elicit tissue nonrestricted tumor suppression
    • Baker-LePain JC, Sarzotti M, Fields TA, Li CY, Nicchitta CV. 2002. GRP94 (gp96) and GRP94 N-terminal geldanamycin binding domain elicit tissue nonrestricted tumor suppression. J. Exp. Med. 196:1447-59
    • (2002) J. Exp. Med. , vol.196 , pp. 1447-1459
    • Baker-LePain, J.C.1    Sarzotti, M.2    Fields, T.A.3    Li, C.Y.4    Nicchitta, C.V.5
  • 78
    • 0037290769 scopus 로고    scopus 로고
    • ISO: A critical evaluation of the role of peptides in heat shock/chaperone protein-mediated tumor rejection
    • Baker-LePain JC, Reed RC, Nicchitta CV. 2003. ISO: a critical evaluation of the role of peptides in heat shock/chaperone protein-mediated tumor rejection. Curr. Opin. Immunol. 15:89-94
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 89-94
    • Baker-LePain, J.C.1    Reed, R.C.2    Nicchitta, C.V.3
  • 80
    • 0042357122 scopus 로고    scopus 로고
    • GRP94/gp96 elicits ERK activation in murine macrophages: A role for endotoxin contamination in NF-κB activation and nitric oxide production
    • Reed RC, Berwin B, Baker JP, Nicchitta CV. 2003. GRP94/gp96 elicits ERK activation in murine macrophages: a role for endotoxin contamination in NF-κB activation and nitric oxide production. J. Biol. Chem. 278:31853-60
    • (2003) J. Biol. Chem. , vol.278 , pp. 31853-31860
    • Reed, R.C.1    Berwin, B.2    Baker, J.P.3    Nicchitta, C.V.4
  • 81
    • 0025155682 scopus 로고
    • Cellular peptide composition governed by major histocompatibility complex class I molecules
    • Falk K, Rötzschke O, Rammensee H-G. 1990. Cellular peptide composition governed by major histocompatibility complex class I molecules. Nature 348:248-51
    • (1990) Nature , vol.348 , pp. 248-251
    • Falk, K.1    Rötzschke, O.2    Rammensee, H.-G.3
  • 82
    • 0031569179 scopus 로고    scopus 로고
    • MHC class I-associated peptides produced from endogenous gene products with vastly different efficiencies
    • Anton LC, Yewdell JW, Bennink JR. 1997. MHC class I-associated peptides produced from endogenous gene products with vastly different efficiencies. J. Immunol. 158:2535-42
    • (1997) J. Immunol. , vol.158 , pp. 2535-2542
    • Anton, L.C.1    Yewdell, J.W.2    Bennink, J.R.3
  • 83
    • 0037242017 scopus 로고    scopus 로고
    • Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I
    • Reits E, Griekspoor A, Neijssen J, Groothuis T, Jalink K, et al. 2003. Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I. Immunity 18:97-108
    • (2003) Immunity , vol.18 , pp. 97-108
    • Reits, E.1    Griekspoor, A.2    Neijssen, J.3    Groothuis, T.4    Jalink, K.5
  • 84
    • 0037443409 scopus 로고    scopus 로고
    • Quantifying recruitment of cytosolic peptides for HLA class I presentation: Impact of TAP transport
    • Fruci D, Lauvau G, Saveanu L, Amicosante M, Butler RH, et al. 2003. Quantifying recruitment of cytosolic peptides for HLA class I presentation: impact of TAP transport. J. Immunol. 170:2977-84
    • (2003) J. Immunol. , vol.170 , pp. 2977-2984
    • Fruci, D.1    Lauvau, G.2    Saveanu, L.3    Amicosante, M.4    Butler, R.H.5
  • 85
    • 0141750441 scopus 로고    scopus 로고
    • The group II chaperonin TRiC protects proteolytic intermediates from degradation in the MHC class I antigen processing pathway
    • Kunisawa J, Shastri N. 2003. The group II chaperonin TRiC protects proteolytic intermediates from degradation in the MHC class I antigen processing pathway. Mol. Cell 12:565-76
    • (2003) Mol. Cell , vol.12 , pp. 565-576
    • Kunisawa, J.1    Shastri, N.2
  • 86
    • 1642456660 scopus 로고    scopus 로고
    • HSP70 peptide binding mutants separate antigen delivery from dendritic cell stimulation
    • MacAry PA, Javid B, Floto RA, Smith KG, Oehlmann W, et al. 2004. HSP70 peptide binding mutants separate antigen delivery from dendritic cell stimulation. Immunity 20:95-106
    • (2004) Immunity , vol.20 , pp. 95-106
    • MacAry, P.A.1    Javid, B.2    Floto, R.A.3    Smith, K.G.4    Oehlmann, W.5
  • 87
    • 2442550745 scopus 로고    scopus 로고
    • Loading of MHC class I and II presentation pathways by exogenous antigens: A quantitative in vivo comparison
    • Storni T, Bachmann MF. 2004. Loading of MHC class I and II presentation pathways by exogenous antigens: a quantitative in vivo comparison. J. Immunol. 172:6129-35
    • (2004) J. Immunol. , vol.172 , pp. 6129-6135
    • Storni, T.1    Bachmann, M.F.2
  • 88
    • 0036668249 scopus 로고    scopus 로고
    • Interactions between dead cells and dendritic cells in the induction of antiviral CTL responses
    • Fonteneau JF, Larsson M, Bhardwaj N. 2002. Interactions between dead cells and dendritic cells in the induction of antiviral CTL responses. Curr. Opin. Immunol. 14:471-77
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 471-477
    • Fonteneau, J.F.1    Larsson, M.2    Bhardwaj, N.3
  • 89
    • 1542511202 scopus 로고    scopus 로고
    • Death-defying immunity: Do apoptotic cells influence antigen processing and presentation?
    • Albert ML. 2004. Death-defying immunity: Do apoptotic cells influence antigen processing and presentation? Nat. Rev. Immunol 4:223-31
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 223-231
    • Albert, M.L.1
  • 90
    • 0037369603 scopus 로고    scopus 로고
    • A role for class A scavenger receptor in dendritic cell nibbling from live cells
    • Harshyne LA, Zimmer MI, Watkins SC, Barratt-Boyes SM. 2003. A role for class A scavenger receptor in dendritic cell nibbling from live cells. J. Immunol. 170:2302-9
    • (2003) J. Immunol. , vol.170 , pp. 2302-2309
    • Harshyne, L.A.1    Zimmer, M.I.2    Watkins, S.C.3    Barratt-Boyes, S.M.4
  • 91
    • 0035869278 scopus 로고    scopus 로고
    • Dendritic cells acquire antigens from live cells for cross-presentation to CTL
    • Harshyne LA, Watkins SC, Gambotto A, Barratt-Boyes SM. 2001. Dendritic cells acquire antigens from live cells for cross-presentation to CTL. J. Immunol. 166:3717-23
    • (2001) J. Immunol. , vol.166 , pp. 3717-3723
    • Harshyne, L.A.1    Watkins, S.C.2    Gambotto, A.3    Barratt-Boyes, S.M.4
  • 92
    • 17644411650 scopus 로고    scopus 로고
    • Regulation of antigen presentation and cross-presentation in the dendritic cell network: Facts, hypothesis, and immunological implications
    • In press
    • Wilson NS, Villadangos JA. 2004. Regulation of antigen presentation and cross-presentation in the dendritic cell network: facts, hypothesis, and immunological implications. Adv. Immunol. In press
    • (2004) Adv. Immunol.
    • Wilson, N.S.1    Villadangos, J.A.2
  • 93
    • 0037067649 scopus 로고    scopus 로고
    • Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages
    • Gagnon E, Duclos S, Rondeau C, Chevet E, Cameron PH, et al. 2002. Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages. Cell 110:119-31
    • (2002) Cell , vol.110 , pp. 119-131
    • Gagnon, E.1    Duclos, S.2    Rondeau, C.3    Chevet, E.4    Cameron, P.H.5
  • 94
    • 18344405138 scopus 로고    scopus 로고
    • Phagosomes are competent organelles for antigen cross-presentation
    • Houde M, Bertholet S, Gagnon E, Brunet S, Goyette G, et al. 2003. Phagosomes are competent organelles for antigen cross-presentation. Nature 425:402-6
    • (2003) Nature , vol.425 , pp. 402-406
    • Houde, M.1    Bertholet, S.2    Gagnon, E.3    Brunet, S.4    Goyette, G.5
  • 95
    • 0141707939 scopus 로고    scopus 로고
    • ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells
    • Guermonprez P, Saveanu L, Kleijmeer M, Davoust J, van Endert P, Amigorena S. 2003. ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells. Nature 425:397-402
    • (2003) Nature , vol.425 , pp. 397-402
    • Guermonprez, P.1    Saveanu, L.2    Kleijmeer, M.3    Davoust, J.4    Van Endert, P.5    Amigorena, S.6
  • 96
    • 0033203120 scopus 로고    scopus 로고
    • Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells
    • Rodriguez A, Regnault A, Kleijmeer M, Ricciardi-Castagnoli P, Amigorena S. 1999. Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells. Nat. Cell Biol. 1:362-68
    • (1999) Nat. Cell Biol. , vol.1 , pp. 362-368
    • Rodriguez, A.1    Regnault, A.2    Kleijmeer, M.3    Ricciardi-Castagnoli, P.4    Amigorena, S.5
  • 97
    • 0031030792 scopus 로고    scopus 로고
    • Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells
    • Norbury CC, Chambers BJ, Prescott AR, Ljunggren HG, Watts C. 1997. Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells. Eur. J. Immunol. 27:280-88
    • (1997) Eur. J. Immunol. , vol.27 , pp. 280-288
    • Norbury, C.C.1    Chambers, B.J.2    Prescott, A.R.3    Ljunggren, H.G.4    Watts, C.5
  • 98
    • 0346521283 scopus 로고    scopus 로고
    • Making sense of mass destruction: Quantitating MHC class I antigen presentation
    • Yewdell JW, Reits E, Neefjes J. 2003. Making sense of mass destruction: quantitating MHC class I antigen presentation. Nat. Rev. Immunol. 3:952-61
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 952-961
    • Yewdell, J.W.1    Reits, E.2    Neefjes, J.3
  • 99
    • 0028501143 scopus 로고
    • Efficiency of MHC class I antigen processing: A quantitative analysis
    • Villanueva MS, Fischer P, Feen K, Pamer EG. 1994. Efficiency of MHC class I antigen processing: a quantitative analysis. Immunity 1:479-89
    • (1994) Immunity , vol.1 , pp. 479-489
    • Villanueva, M.S.1    Fischer, P.2    Feen, K.3    Pamer, E.G.4
  • 100
    • 0037046536 scopus 로고    scopus 로고
    • Transient aggregation of ubiquitinated proteins during dendritic cell maturation
    • Lelouard H, Gatti E, Cappello F, Gresser O, Camosseto V, Pierre P. 2002. Transient aggregation of ubiquitinated proteins during dendritic cell maturation. Nature 417:177-82
    • (2002) Nature , vol.417 , pp. 177-182
    • Lelouard, H.1    Gatti, E.2    Cappello, F.3    Gresser, O.4    Camosseto, V.5    Pierre, P.6
  • 101
    • 1442358797 scopus 로고    scopus 로고
    • Dendritic cell aggresome-like induced structures are dedicated areas for ubiquitination and storage of newly synthesized defective proteins
    • Lelouard H, Ferrand V, Marguet D, Bania J, Camosseto V, et al. 2004. Dendritic cell aggresome-like induced structures are dedicated areas for ubiquitination and storage of newly synthesized defective proteins. J. Cell Biol. 164:667-75
    • (2004) J. Cell Biol. , vol.164 , pp. 667-675
    • Lelouard, H.1    Ferrand, V.2    Marguet, D.3    Bania, J.4    Camosseto, V.5
  • 102
    • 0141872929 scopus 로고    scopus 로고
    • Recombinant antibodies with MHC-restricted, peptide-specific. T-cell receptor-like specificity: New tools to study antigen presentation and TCR-peptide-MHC interactions
    • Cohen CJ, Denkberg G, Lev A, Epel M, Reiter Y. 2003. Recombinant antibodies with MHC-restricted, peptide-specific, T-cell receptor-like specificity: new tools to study antigen presentation and TCR-peptide-MHC interactions. J. Mol. Recognit. 16:324-32
    • (2003) J. Mol. Recognit. , vol.16 , pp. 324-332
    • Cohen, C.J.1    Denkberg, G.2    Lev, A.3    Epel, M.4    Reiter, Y.5
  • 103
    • 0036127888 scopus 로고    scopus 로고
    • Development and use of multimeric major histocompatibility complex molecules
    • Greten TF, Schneck JP. 2002. Development and use of multimeric major histocompatibility complex molecules. Clin. Diagn. Lab. Immunol. 9:216-20
    • (2002) Clin. Diagn. Lab. Immunol. , vol.9 , pp. 216-220
    • Greten, T.F.1    Schneck, J.P.2
  • 104
    • 3042616595 scopus 로고    scopus 로고
    • A membrane protein required for dislocation of misfolded proteins from the ER
    • Lilley BN, Ploegh HL. 2004. A membrane protein required for dislocation of misfolded proteins from the ER. Nature 429:834-40
    • (2004) Nature , vol.429 , pp. 834-840
    • Lilley, B.N.1    Ploegh, H.L.2
  • 105
    • 3042677637 scopus 로고    scopus 로고
    • A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
    • Ye Y, Shibata Y, Yun C, Ron D, Rapoport TA. 2004. A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature 429:841-47
    • (2004) Nature , vol.429 , pp. 841-847
    • Ye, Y.1    Shibata, Y.2    Yun, C.3    Ron, D.4    Rapoport, T.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.